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Role of milk-derived antibacterial peptides in modern food biotechnology: their synthesis, applications and future perspectives
Zitieren Sie bitte immer diese URN: urn:nbn:de:bvb:20-opus-197610
- Milk-derived antibacterial peptides (ABPs) are protein fragments with a positive influence on the functions and conditions of a living organism. Milk-derived ABPs have several useful properties important for human health, comprising a significant antibacterial effect against various pathogens, but contain toxic side-effects. These compounds are mainly produced from milk proteins via fermentation and protein hydrolysis. However, they can also be produced using recombinant DNA techniques or organic synthesis. This review describes the role ofMilk-derived antibacterial peptides (ABPs) are protein fragments with a positive influence on the functions and conditions of a living organism. Milk-derived ABPs have several useful properties important for human health, comprising a significant antibacterial effect against various pathogens, but contain toxic side-effects. These compounds are mainly produced from milk proteins via fermentation and protein hydrolysis. However, they can also be produced using recombinant DNA techniques or organic synthesis. This review describes the role of milk-derived ABPs in modern food biotechnology with an emphasis on their synthesis and applications. Additionally, we also discuss the mechanisms of action and the main bioproperties of ABPs. Finally, we explore future perspectives for improving ABP physicochemical properties and diminishing their toxic side-effects.…
Autor(en): | Muhammad Usman Khan, Maryam Pirzadeh, Carola Yvette Förster, Sergey Shityakov, Mohammad Ali Shariati |
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URN: | urn:nbn:de:bvb:20-opus-197610 |
Dokumentart: | Artikel / Aufsatz in einer Zeitschrift |
Institute der Universität: | Medizinische Fakultät / Klinik und Poliklinik für Anästhesiologie (ab 2004) |
Sprache der Veröffentlichung: | Englisch |
Titel des übergeordneten Werkes / der Zeitschrift (Englisch): | Biomolecules |
ISSN: | 2218-273X |
Erscheinungsjahr: | 2018 |
Band / Jahrgang: | 8 |
Heft / Ausgabe: | 4 |
Seitenangabe: | 110 |
Originalveröffentlichung / Quelle: | Biomolecules 2018, 8(4), 110; https://doi.org/10.3390/biom8040110 |
DOI: | https://doi.org/10.3390/biom8040110 |
Allgemeine fachliche Zuordnung (DDC-Klassifikation): | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Freie Schlagwort(e): | antibacterial activity; bioactive peptide; fermentation; milk proteins; peptide synthesis; protein hydrolysis; recombinant DNA |
Datum der Freischaltung: | 06.05.2020 |
Datum der Erstveröffentlichung: | 05.10.2018 |
Lizenz (Deutsch): | CC BY: Creative-Commons-Lizenz: Namensnennung 4.0 International |