Sila-Analoga des Mebrophenhydramins
Sila-Analogues of Mebrophenhydramine
Please always quote using this URN: urn:nbn:de:bvb:20-opus-63542
- Sila-analogues A 2, B 2 and C 2 of the drug mebrophenhydramine from the class of benzhydryl ethers -were synthesized for the first time by the steps shown in scheme 1, and they and their precurso:rs I-Ill were characterized by their physical (Table 1) and chemical properties, a.nd their structures confirmed by NMR, mass and infrared spectroscopy (Tables 3-5). The histaminolytic and anticholinergic effects of A 2 and C 2 were investigated and compared with some structure-activity relationships of analogue carbon compounds.
| Author: | Reinhold Tacke, U. Wannagat |
|---|---|
| URN: | urn:nbn:de:bvb:20-opus-63542 |
| Document Type: | Journal article |
| Faculties: | Fakultät für Chemie und Pharmazie / Institut für Anorganische Chemie |
| Language: | German |
| Year of Completion: | 1976 |
| Source: | In: Monatshefte für Chemie (1976) 107, 2, 439-447. |
| Dewey Decimal Classification: | 5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften |
| GND Keyword: | Anorganische Chemie |
| Release Date: | 2012/02/01 |
| Licence (German): |  Deutsches Urheberrecht |