Comorbidity in bullous pemphigoid: up-date and clinical implications
Please always quote using this URN: urn:nbn:de:bvb:20-opus-321671
- Bullous pemphigoid is the most common autoimmune blistering disease in industrialized countries and particularly affects the elderly. In this patient population, comorbid diseases are frequent and may complicate management and treatment of bullous pemphigoid. A better understanding why distinct diseases are more frequent in bullous pemphigoid patients may lead to new pathophysiological insights and - as a consequence - result in better patient care. The association of bullous pemphigoid with neurological and psychiatric diseases is well knownBullous pemphigoid is the most common autoimmune blistering disease in industrialized countries and particularly affects the elderly. In this patient population, comorbid diseases are frequent and may complicate management and treatment of bullous pemphigoid. A better understanding why distinct diseases are more frequent in bullous pemphigoid patients may lead to new pathophysiological insights and - as a consequence - result in better patient care. The association of bullous pemphigoid with neurological and psychiatric diseases is well known and confirmed by several case-control studies. Association with further diseases such as malignancy and metabolic diseases are still discussed controversially. In recent years new relationships between bullous pemphigoid and autoimmune as well as inflammatory skin diseases have been reported. This review provides a systematic overview on studies addressing comorbidity in bullous pemphigoid patients. Increasing the awareness of both, common and rare comorbid diseases, may enable clinicians to optimize patient support and individualized treatment of bullous pemphigoid.…
Author: | Johanna Huttelmaier, Sandra Benoit, Matthias Goebeler |
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URN: | urn:nbn:de:bvb:20-opus-321671 |
Document Type: | Journal article |
Faculties: | Medizinische Fakultät / Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie |
Language: | English |
Parent Title (English): | Frontiers in Immunology |
Year of Completion: | 2023 |
Volume: | 14 |
Article Number: | 1196999 |
Source: | Frontiers in Immunology (2023) 14:1196999. https://doi.org/10.3389/fimmu.2023.1196999 |
DOI: | https://doi.org/10.3389/fimmu.2023.1196999 |
Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Tag: | autoimmune skin blistering disease; bullous pemphigoid; comorbidity; inflammatory disease; malignancy; metabolic disease; neurologic disease |
Release Date: | 2024/05/31 |
Licence (German): | CC BY: Creative-Commons-Lizenz: Namensnennung 4.0 International |