Regular consumption of Lactobacillus reuteri-containing lozenges reduces pregnancy gingivitis: an RCT
Zitieren Sie bitte immer diese URN: urn:nbn:de:bvb:20-opus-186783
- Aim: This randomized controlled trial assessed the impact of Lactobacillus reuteri on pregnancy gingivitis in healthy women. Materials and Methods: Forty-five healthy women (24 test/21 placebo) with pregnancy gingivitis in the third trimester of pregnancy were enrolled. At baseline Gingival Index (GI) and Plaque Index (PlI) were assessed at the Ramfjord teeth and venous blood taken for TNF-alpha analysis. Subsequently participants were randomly provided with lozenges to be consumed 2 9 daily until birth (approx. 7 weeks) containing >=Aim: This randomized controlled trial assessed the impact of Lactobacillus reuteri on pregnancy gingivitis in healthy women. Materials and Methods: Forty-five healthy women (24 test/21 placebo) with pregnancy gingivitis in the third trimester of pregnancy were enrolled. At baseline Gingival Index (GI) and Plaque Index (PlI) were assessed at the Ramfjord teeth and venous blood taken for TNF-alpha analysis. Subsequently participants were randomly provided with lozenges to be consumed 2 9 daily until birth (approx. 7 weeks) containing >= 10(8) CFU L. reuteri ATCC PTA 5289 and >= 10(8) CFU L. reuteri DSM 17938 (test) or being devoid of L. reuteri (placebo). Within 2 days after birth recording of GI, PlI and blood sampling were repeated. Results: At baseline, mean GI and mean PlI did not differ significantly between both groups. In the test group mean TNF-alpha serum level was significantly (p < 0.02) lower than in the placebo group. At reevaluation, mean GI and mean PlI of the test group were both significantly (p < 0.0001) lower than in the placebo group. Mean TNF-alpha serum level did no longer differ significantly between the groups. Conclusions: The consumption of L. reuteri lozenges may be a useful adjunct in the control of pregnancy gingivitis.…
Autor(en): | Ulrich Schlagenhauf, Lena Jakob, Martin Eigenthaler, Sabine Segerer, Yvonne Jockel-Schneider, Monika Rehn |
---|---|
URN: | urn:nbn:de:bvb:20-opus-186783 |
Dokumentart: | Artikel / Aufsatz in einer Zeitschrift |
Institute der Universität: | Medizinische Fakultät / Frauenklinik und Poliklinik |
Medizinische Fakultät / Klinik und Polikliniken für Zahn-, Mund- und Kieferkrankheiten | |
Medizinische Fakultät / Abteilung für Parodontologie (in der Poliklinik für Zahnerhaltung und Parodontologie) | |
Sprache der Veröffentlichung: | Englisch |
Titel des übergeordneten Werkes / der Zeitschrift (Englisch): | Journal of Clinical Periodontology |
Erscheinungsjahr: | 2016 |
Band / Jahrgang: | 43 |
Heft / Ausgabe: | 11 |
Seitenangabe: | 948-954 |
Originalveröffentlichung / Quelle: | Journal of Clinical Periodontology |
DOI: | https://doi.org/10.1111/jcpe.12606 |
Allgemeine fachliche Zuordnung (DDC-Klassifikation): | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Freie Schlagwort(e): | L. reuteri; bacteria; chronic periodontitis; disease; microbiota; plaque; postpartum; pregnancy; pregnancy gingivitis; probiotic lozenges; subgingival |
Datum der Freischaltung: | 27.05.2020 |
Lizenz (Deutsch): | CC BY: Creative-Commons-Lizenz: Namensnennung 4.0 International |