Dual-energy CT angiography in suspected pulmonary embolism: influence of injection protocols on image quality and perfused blood volume
Please always quote using this URN: urn:nbn:de:bvb:20-opus-314739
- Abstract To compare intravenous contrast material (CM) injection protocols for dual-energy CT pulmonary angiography (CTPA) in patients with suspected acute pulmonary embolism with regard to image quality and pulmonary perfused blood volume (PBV) values. A total of 198 studies performed with four CM injection protocols varying in CM volume and iodine delivery rates (IDR) were retrospectively included: (A) 60 ml at 5 ml/s (IDR = 1.75gI/s), (B) 50 ml at 5 ml/s (IDR = 1.75gI/s), (C) 50 ml at 4 ml/s (IDR = 1.40gI/s), (D) 40 ml at 3 ml/sAbstract To compare intravenous contrast material (CM) injection protocols for dual-energy CT pulmonary angiography (CTPA) in patients with suspected acute pulmonary embolism with regard to image quality and pulmonary perfused blood volume (PBV) values. A total of 198 studies performed with four CM injection protocols varying in CM volume and iodine delivery rates (IDR) were retrospectively included: (A) 60 ml at 5 ml/s (IDR = 1.75gI/s), (B) 50 ml at 5 ml/s (IDR = 1.75gI/s), (C) 50 ml at 4 ml/s (IDR = 1.40gI/s), (D) 40 ml at 3 ml/s (IDR = 1.05gI/s). Image quality and PBV values at different resolution settings were compared. Pulmonary arterial tract attenuation was highest for protocol A (397 ± 110 HU; p vs. B = 0.13; vs. C = 0.02; vs. D < 0.001). CTPA image quality of protocol A was rated superior compared to protocols B and D by reader 1 (p = 0.01; < 0.001), and superior to protocols B, C and D by reader 2 (p < 0.001; 0.02; < 0.001). Otherwise, there were no significant differences in CTPA quality ratings. Subjective iodine map ratings did not vary significantly between protocols A, B, and C. Both readers rated protocol D inferior to all other protocols (p < 0.05). PBV values did not vary significantly between protocols A and B at resolution settings of 1, 4 and 10 (p = 0.10; 0.10; 0.09), while otherwise PBV values displayed a decreasing trend from protocol A to D (p < 0.05). Higher CM volume and IDR are associated with superior CTPA and iodine map quality and higher absolute PBV values.…
Author: | Aleksander KosmalaORCiD, Philipp GruschwitzORCiD, Simon VeldhoenORCiD, Andreas Max WengORCiD, Bernhard Krauss, Thorsten Alexander Bley, Bernhard PetritschORCiD |
---|---|
URN: | urn:nbn:de:bvb:20-opus-314739 |
Document Type: | Journal article |
Faculties: | Medizinische Fakultät / Institut für diagnostische und interventionelle Radiologie (Institut für Röntgendiagnostik) |
Language: | English |
Parent Title (English): | The International Journal of Cardiovascular Imaging |
ISSN: | 1569-5794 |
ISSN: | 1573-0743 |
Year of Completion: | 2020 |
Volume: | 36 |
Issue: | 10 |
Pagenumber: | 2051-2059 |
Source: | The International Journal of Cardiovascular Imaging (2020) 36:10, 2051-2059. https://doi.org/10.1007/s10554-020-01911-8 |
DOI: | https://doi.org/10.1007/s10554-020-01911-8 |
Pubmed Id: | https://pubmed.ncbi.nlm.nih.gov/32506286 |
Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Tag: | CT; contrast media; dual-energy CT; pulmonary embolism |
Release Date: | 2024/06/18 |
Date of first Publication: | 2020/10/01 |
Licence (German): | CC BY: Creative-Commons-Lizenz: Namensnennung 4.0 International |