Oncolytic Virotherapy of Canine and Feline Cancer
Zitieren Sie bitte immer diese URN: urn:nbn:de:bvb:20-opus-119753
- Cancer is the leading cause of disease-related death in companion animals such as dogs and cats. Despite recent progress in the diagnosis and treatment of advanced canine and feline cancer, overall patient treatment outcome has not been substantially improved. Virotherapy using oncolytic viruses is one promising new strategy for cancer therapy. Oncolytic viruses (OVs) preferentially infect and lyse cancer cells, without causing excessive damage to surrounding healthy tissue, and initiate tumor-specific immunity. The current review describes theCancer is the leading cause of disease-related death in companion animals such as dogs and cats. Despite recent progress in the diagnosis and treatment of advanced canine and feline cancer, overall patient treatment outcome has not been substantially improved. Virotherapy using oncolytic viruses is one promising new strategy for cancer therapy. Oncolytic viruses (OVs) preferentially infect and lyse cancer cells, without causing excessive damage to surrounding healthy tissue, and initiate tumor-specific immunity. The current review describes the use of different oncolytic viruses for cancer therapy and their application to canine and feline cancer.…
Autor(en): | Ivaylo Gentschev, Sadeep S. Patil, Ivan Petrov, Joseph Cappello, Marion Adelfinger, Aladar A. Szalay |
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URN: | urn:nbn:de:bvb:20-opus-119753 |
Dokumentart: | Artikel / Aufsatz in einer Zeitschrift |
Institute der Universität: | Fakultät für Chemie und Pharmazie / Lehrstuhl für Biochemie |
Sprache der Veröffentlichung: | Englisch |
Titel des übergeordneten Werkes / der Zeitschrift (Englisch): | Viruses |
Erscheinungsjahr: | 2014 |
Band / Jahrgang: | 6 |
Heft / Ausgabe: | 5 |
Seitenangabe: | 2122-2137 |
Originalveröffentlichung / Quelle: | Viruses 2014, 6, 2122-2137; doi:10.3390/v6052122 |
DOI: | https://doi.org/10.3390/v6052122 |
Allgemeine fachliche Zuordnung (DDC-Klassifikation): | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Freie Schlagwort(e): | cancer; canine and feline cancer therapy; oncolysis; oncolytic virus |
Datum der Freischaltung: | 12.11.2015 |
Lizenz (Deutsch): | CC BY: Creative-Commons-Lizenz: Namensnennung |