Refine
Has Fulltext
- yes (11)
Is part of the Bibliography
- yes (11)
Document Type
- Journal article (10)
- Other (1)
Language
- English (11) (remove)
Keywords
- pregnancy (11) (remove)
Institute
- Klinik und Poliklinik für Psychiatrie, Psychosomatik und Psychotherapie (4)
- Frauenklinik und Poliklinik (2)
- Klinik und Poliklinik für Anästhesiologie (ab 2004) (2)
- Abteilung für Parodontologie (in der Poliklinik für Zahnerhaltung und Parodontologie) (1)
- Institut für Pharmakologie und Toxikologie (1)
- Institut für Psychologie (1)
- Institut für Systemimmunologie (1)
- Kinderklinik und Poliklinik (1)
- Klinik und Polikliniken für Zahn-, Mund- und Kieferkrankheiten (1)
- Theodor-Boveri-Institut für Biowissenschaften (1)
In 55 chronic schizophrenics, the occurrence of infectious diseases during their mothers' pregnancies was investigated. Different psychiatrie diagnostic systems were compared. Infections were reported by the mothers of familial and sporadic DSM I1I-R schizophrenics in equal proportion. However, applying Leonhard's classification, the frequency of infections was found to be significantly increased in 'systematic' schizophrenia (mainly exogenously induced in the view of Leonhard) compared to 'unsystematic' schizophrenia (mainly genetically determined according to Leonhard's findings). Most of the infections occurred during the second trimester (nine out of 13). Thus, in the 'systematic' forms of schizophrenia (low genetic loading), maternal infections in this crucial period of neurodevelopment would appear to be important causative factors in the cytoarchitectural deviance detected in the central nervous system of schizophrenics.