Refine
Year of publication
- 2019 (435) (remove)
Document Type
- Journal article (435) (remove)
Language
- English (435) (remove)
Keywords
- apoptosis (8)
- boron (6)
- inflammation (6)
- ischemic stroke (5)
- DNA methylation (4)
- cancer (4)
- cancer therapy (4)
- children (4)
- deep brain stimulation (4)
- infection (4)
- measles virus (4)
- multiple myeloma (4)
- sphingolipids (4)
- GABA (3)
- Meningitis (3)
- Monte-Carlo (3)
- Neisseria meningitidis (3)
- Physics (3)
- Survival (3)
- Ureaplasma parvum (3)
- Ureaplasma urealyticum (3)
- aging (3)
- blood–brain barrier (3)
- boranes (3)
- climate change (3)
- cytokines (3)
- cytotoxicity (3)
- death receptors (3)
- epigenetics (3)
- gephyrin (3)
- length of stenosis (3)
- leukemic cells (3)
- lysosome (3)
- machine learning (3)
- metagenomics (3)
- microbiome (3)
- psychiatric disorders (3)
- remote sensing (3)
- stem cells (3)
- tissue engineering (3)
- virtual reality (3)
- 3D tissue model (2)
- Bees (2)
- Biomedical engineering (2)
- C-reactive protein (2)
- CXCR4 (2)
- Cancer (2)
- Candida albicans (2)
- Colonization (2)
- Constraints (2)
- Cross-Section (2)
- Cryo-EM (2)
- Decay (2)
- Exercise capacity (2)
- Expression (2)
- FKBP5 (2)
- GABAA receptors (2)
- HBMEC (2)
- HBV (2)
- HIV (2)
- Hadron colliders (2)
- HeLa cells (2)
- Imaging techniques (2)
- Impact (2)
- MSC (2)
- Metabolomics (2)
- Methylation (2)
- NHC (2)
- Neural circuits (2)
- Neurons (2)
- PIP2 (2)
- Pair Production (2)
- Parton Distributions (2)
- Parton distributions (2)
- Radiative-corrections (2)
- Reduction (2)
- S-ADAPT (2)
- Sentinel-1 (2)
- Solution-state NMR (2)
- Stem cells (2)
- TNF receptor superfamily (2)
- TNF superfamily (2)
- TNFR1 (2)
- TRAIL (2)
- Tanzania (2)
- Top-Quark (2)
- VEGF (2)
- adolescents (2)
- allometric scaling (2)
- antibody (2)
- antibody fusion proteins (2)
- artemisinin (2)
- autophagy (2)
- bacteria (2)
- blood-brain barrier (2)
- body composition (2)
- body size (2)
- cAArC (2)
- calcium phosphate cement (2)
- cardiomyopathy (2)
- carotid atherosclerosis (2)
- carotid stenosis (2)
- carotid ultrasound (2)
- caspase-8 (2)
- cell death (2)
- cell imaging (2)
- chemistry (2)
- colorectal cancer (2)
- complexes (2)
- copper (2)
- cystic fibrosis patients (2)
- degree of stenosis (2)
- dendritic cells (2)
- density functional calculations (2)
- depression (2)
- diazepam (2)
- ecology (2)
- fluorescence (2)
- genetics (2)
- genome annotation (2)
- genome assembly (2)
- geomorphology (2)
- glioblastoma multiforme (2)
- glucocorticoid receptor (2)
- healthy volunteers (2)
- immunotherapy (2)
- inhibitory neurotransmission (2)
- interleukin-8 (2)
- irradiation (2)
- knockout (2)
- magnetic resonance imaging (2)
- melt electrospinning writing (2)
- meningitis (2)
- mental health (2)
- mesencephalic locomotor region (2)
- metabolic adaptation (2)
- migration (2)
- mitochondria (2)
- mouse (2)
- multiple sclerosis (2)
- neuroinflammation (2)
- neurology (2)
- neuroprotection (2)
- oncolytic virus (2)
- outcome (2)
- p53 (2)
- pathogens (2)
- performance (2)
- personalized medicine (2)
- photothrombotic stroke (2)
- polycyclic aromatic hydrocarbons (2)
- polymers (2)
- population pharmacokinetics (2)
- presence (2)
- radicals (2)
- recurrence (2)
- relapse (2)
- ring-expansion reaction (2)
- risk factors (2)
- smartphone app (2)
- stroke (2)
- structure (2)
- surgery (2)
- survival (2)
- tight junction (2)
- trade-offs (2)
- two-photon excited fluorescence (2)
- ubiquitin (2)
- (classical and atypical) Werner syndrome (1)
- + (1)
- ++ (1)
- 18F-FDS (1)
- 2 Jets (1)
- 2-deoxy-2-18F-fluoro-D-sorbitol (1)
- 25-hydroxycholesterol 7 alpha-hydroxylase (1)
- 2Dimensionale Spektroskopie (1)
- 3-coordinate organoboron compounds (1)
- 3D (1)
- 3D printing (1)
- 3D remote sensing (1)
- 3 T (1)
- 4D flow (1)
- ABP1 (1)
- AHRR (1)
- ALAN (1)
- AMP-activated kinases (1)
- APRI (1)
- ARCI (1)
- ARCI EM type III (1)
- ATP generation (1)
- AUX1 (1)
- Accurate (1)
- Acids (1)
- Activation (1)
- Active disease (1)
- Acute myeloid leukemia (AML) (1)
- AdS-CFT Correspondence (1)
- Adherens junction (1)
- Adolescent (1)
- Adult (1)
- Akt/PKB (1)
- Alcohol dependence (1)
- Algorithm (1)
- Alien limb syndrome (1)
- Allogeneic transplantation (1)
- Alpine habitats (1)
- Alzheimer's disease (1)
- Anarchic limb syndrome (1)
- Andalusian varieties (1)
- Annotation (1)
- Anomalous magnetic-moment (1)
- Antarctica (1)
- Anthropocene (1)
- Antioxidants (1)
- Anxiety (1)
- Aortic arch (1)
- Apidae (1)
- Apis mellifera (1)
- Aplastic anemia (1)
- Apoptosis (1)
- Applied physics (1)
- Archaeology (1)
- Arylborylene Complexes (1)
- Ascaris lumbricoides (1)
- Aspergillus (1)
- Aspergillus fumigalus (1)
- Associative learning (1)
- Astrophysical neutrino sources (1)
- Atacama (1)
- Atmospheric muons (1)
- Atomic and molecular interactions with photons (1)
- Atrial fibrillation (1)
- Autologous hematopoietic stem cell transplantation (1)
- B cell malignancies (1)
- B cells (1)
- B,N-heterocylcles (1)
- B-B bond activation (1)
- B-MYB (1)
- B7-H1 (1)
- BAL (1)
- BCG (1)
- BMI (1)
- BRAF mutation (1)
- BRCA1 (1)
- Barrier (1)
- Behavioural ecology (1)
- Benzimidazole (1)
- Berberine (1)
- Bevacizumab (1)
- Bhabha Scattering (1)
- Binge drinking (1)
- Biomarke (1)
- Biophysics (1)
- Bipolar disorder (1)
- Bistability (1)
- Black Holes in String Theory (1)
- Black-hole (1)
- Blood (1)
- Body schema (1)
- Boson (1)
- Bosons (1)
- Brain cancer (1)
- Brain diseases (1)
- Brain endothelial cells (1)
- Branching fractions (1)
- Bronchopulmonary dysplasia (1)
- By-Light Scattering (1)
- B−H activation (1)
- C-60 fullerene (1)
- C-C coupling (1)
- C3a (1)
- C3aR (1)
- C5a (1)
- C5aR1 (1)
- C5aR2 (1)
- C60 fullerene (1)
- CAR T cells (1)
- CCI (1)
- CD274 (1)
- CD4+ T cells (1)
- CD8+ T cells (1)
- CD95 (1)
- CERN (1)
- CIDP (1)
- CMV (1)
- CO sensing (1)
- CO‐releasing molecules (CORMs) (1)
- CRH1 (1)
- CRMO (1)
- CXCL5 (1)
- CXCL8 (1)
- CXCR2 (1)
- CYP1B1 (1)
- C\(_{60}\) fullerene (1)
- Callyspongia siphonella (1)
- Cancer Cell (1)
- Cancer genetics (1)
- Capicua transcriptional repressor (1)
- Cardiac ventricles (1)
- Cardiovascular diseases (1)
- Cardiovascular risk factors (1)
- Cardiovascular risk prediction (1)
- Carotid intima-media thickness (CIMT) (1)
- Carotid segment (1)
- Carotid ultrasound (1)
- Caspase (1)
- Cell stainin (1)
- Cellular neuroscience (1)
- Central nervous system (1)
- Chambers (1)
- Characterization and analytical techniques (1)
- Chemical composition (1)
- Cherenkov underwater neutrino telescope (1)
- Children (1)
- Chile (1)
- Chili RNA Aptamer (1)
- Chlamydia trachomatis (1)
- Choice Behavior/physiology (1)
- Circinella (1)
- Circular dichroism (1)
- Clinically silent stroke (1)
- Cognitive behavior (1)
- Cognitive neuroscience (1)
- Community-acquired methicillin-resistant Staphylococcus aureus (1)
- Computational and Systems Biology (1)
- Computed axial tomography (1)
- Computer modelling (1)
- Conditioning regimen (1)
- Confocal microscopy (1)
- Conifers (1)
- Conservation (1)
- Consistent partial least squares (1)
- Corticobasal syndrome (1)
- Corticosteroids (1)
- Cosmic-rays (1)
- Couplings (1)
- CpG (1)
- Cranial sutures (1)
- Cross-section (1)
- Cushing’s disease (1)
- Cutaneous lymphoma (1)
- Cystic fibrosis (1)
- Cytochrome P 450 pathway (1)
- Cytosol (1)
- DC gate (1)
- DEM (1)
- DLS and AFM measurements (1)
- DNA damage (1)
- DNA electronic transport (1)
- DNA methyltransferases (1)
- DNA repair (1)
- DNA sequencing (1)
- DNA weight (1)
- DNA-repair (1)
- DNA-repair genes (1)
- DSB focus substructure (1)
- DSM (1)
- Dark-Matter (1)
- Dark-matter (1)
- Data acquisition (1)
- Deep Inelastic-scattering (1)
- Delbruck Scattering (1)
- Densovirus (1)
- Design (1)
- Developmental biology (1)
- Diagnosis prediction (1)
- Diagnostic medicine (1)
- Diffusion tensor imaging (1)
- Dihydroboranes (1)
- Disease severity (1)
- Dopamine (1)
- Double-Beta Decay (1)
- Doxorubicin (1)
- Drosophila (1)
- Drug discovery (1)
- Drug resistance (1)
- Dynamics (1)
- E(+)E(-) collicions (1)
- E2 conjugating enzyme (1)
- E3 ligating enzyme (1)
- EBF1 (1)
- EEA (1)
- ER-Stress (1)
- ERK (1)
- ERK signaling (1)
- ERK1/2 (1)
- ESAT‐6‐like secretion system (1)
- ESS (1)
- EUROASPIRE (1)
- EWAS (1)
- Earth observation (1)
- Echinococcosis (1)
- Echinococcus (1)
- Ecology (1)
- Efflux transport (1)
- Eigenvectors (1)
- Elderly (1)
- Electrical impedance tomography (1)
- Electromagnetic signals (1)
- Electron (1)
- Electroweak Measurements (1)
- Electroweak Phase-Transition (1)
- Electroweak interaction (1)
- Elissen-Palm flux (1)
- Embryonic induction (1)
- Embryos (1)
- Emergence (1)
- Endoplasmic-Reticulum Stress (1)
- Energy (1)
- Enhancer elements (1)
- Entanglement (1)
- Environmental impact (1)
- Epidemiology (1)
- Epigenetic (1)
- Epigenetic regulation (1)
- Epstein-Barr virus-induced gene 2 (1)
- Equipment (1)
- EsaA (1)
- Escherichia coli (1)
- European Spanish (1)
- European group (1)
- Event builder (1)
- Events GW150914 (1)
- Evolutionary developmental biology (1)
- Evolutionary emergence (1)
- Exercise testing (1)
- Extensions of gauge sector (1)
- Extracellular matrix (1)
- Extracellular volume (1)
- Extramedullary disease (1)
- Extreme flows (1)
- Exziton (1)
- Eye Movements/physiology (1)
- Eye development (1)
- FIB-4 (1)
- Fak regulation (1)
- Familial Beckwith-Wiedemann syndrome (1)
- FasL (1)
- Fatigue (1)
- Fats (1)
- Fear conditioning (1)
- Female (1)
- Fgf-signalling (1)
- Flavor Violation (1)
- Flowering plants (1)
- Flowers (1)
- Fludarabine (1)
- Fludarabine-treosulfan (FT) (1)
- Fluorescence spectroscopy (1)
- Forces (1)
- Forests (1)
- Fractional cover analysis (1)
- Full body ownership illusion (1)
- Fusarium (1)
- G-2 (1)
- GABAA (1)
- GAD1 (1)
- GRP78 (1)
- GSV (1)
- GVHD (1)
- Galactic sources (1)
- Gaseous detectors (1)
- Gauge bosons (1)
- Gauge-gravity correspondence (1)
- Gaussian approximation (1)
- Gene expression analysis (1)
- Gene silencing (1)
- General anaesthesia (1)
- Generation (1)
- Genome (1)
- Genomics (1)
- Genotype (1)
- Geriatric care (1)
- Geriatrics (1)
- Germany (1)
- Germline (1)
- Getz Ice Shelf (1)
- Glioblastoma (1)
- Glutathione (1)
- Google Earth Engine (1)
- Gravitons (1)
- Greenland ice sheet (1)
- Group B Streptococcus (1)
- Gruppo-italiano (1)
- H-infinity (1)
- HCV (1)
- HDAC (1)
- HEMA (1)
- HNSCC (1)
- HPA axis (1)
- HRQOL (1)
- Hadron-Hadron scattering (experiments) (1)
- Hadron-hadron interactions (1)
- Haemophilus influenzae (1)
- Health (1)
- Heart (1)
- Heart failure (1)
- Hematopoietic Stem (1)
- Hematopoietic cell transplant (1)
- Heme-regulated inhibitor (1)
- Hemipelvectomy (1)
- Hfq (1)
- Higgy-Boson (1)
- High grade glioma (1)
- High-Energies (1)
- Hindbrain (1)
- Histone deacetylase (1)
- Hodgkin lymphoma (1)
- Honey bees (1)
- Hordeum vulgare (1)
- Host-parasite interaction (1)
- Human Muse Cells (1)
- Human behaviour (1)
- Humans (1)
- Hunsrueck (1)
- Hyperosmotic Stress (1)
- Hypothalamus (1)
- Hypothetical gauge bosons (1)
- IFN (1)
- IL-10 (1)
- IP3 (1)
- Icecube (1)
- Immune system (1)
- Immune-related adverse event (1)
- Immunology (1)
- Immunoprecipitation (1)
- Impella (1)
- Implicit and explicit reward learning (1)
- InSAR (1)
- InSAR height (1)
- Incontinentia pigmenti (1)
- Induced apoptosis (1)
- Inducible Clindamycin Resistance (1)
- Infectious disease (1)
- Inflammatio (1)
- Inflammatory diseases (1)
- Insect flight (1)
- Interleukin-10 (1)
- Interleukin-6 (1)
- Ipilimumab (1)
- Ischemic stroke (1)
- JAK2 (1)
- KDELR2 (1)
- KIF (1)
- KIF11 (1)
- KM3NeT (1)
- Kilombero (1)
- Knee (1)
- LATE DEATHS (1)
- LC-HRESIMS (1)
- LHC (1)
- LSD1 (1)
- LST (1)
- Land Change Modeler (1)
- Landsat time series (1)
- Lantana camara (1)
- Laparoscopy (1)
- Large Hadron Collider (1)
- Late mortality (1)
- Latin America (1)
- Learning and memory (1)
- Learning/physiology (1)
- Leptonic (1)
- Lichtheimia (1)
- Lifetime spectroscopy (1)
- Limb development (1)
- Limb salvage (1)
- Limestone (1)
- Llullaillaco Volcano (1)
- Low risk alcohol use (1)
- Lung disease, (1)
- Lymph nodes (1)
- Lysine-specific methylase (1)
- M14 carboxypeptidasses (1)
- MASS (1)
- MCP1 (1)
- MDSC (1)
- MGMT promoter methylation (1)
- MIBG (1)
- MLST (1)
- MODIS (1)
- MOLLI (1)
- MRI spectroscopy (1)
- Maculinea butterfly (1)
- Magnetic resonance imaging (1)
- Male (1)
- Manganese Carbonyl ligands (1)
- Masticatory mucosa (1)
- Mastoid process (1)
- Matter (1)
- Mc4r (1)
- Measurement error correlation (1)
- Meat (1)
- Mechanisms (1)
- Medical research (1)
- Melanoma (1)
- Memory B cells (1)
- Mesenchymal stem/stromal cells (1)
- Messenger-RNAs (1)
- Methicillin-resistant Staphylococcus aureus (1)
- Mfn2 KO mice (1)
- Microbiology and Infectious Disease (1)
- Midollo-Osseo (1)
- Migration (1)
- Minimal change disease (1)
- Minimally invasive surgery (1)
- Missing Energy (1)
- Mitochondria (1)
- Mobile genetic element (1)
- Model specification (1)
- Monte Carlo simulation (1)
- Motor behaviour (1)
- Mouse (1)
- Movement behavior (1)
- Mucor (1)
- Mucorales (1)
- Multiple (1)
- Multiple myeloma (1)
- Multiple-Scattering (1)
- Multiplex PCR (1)
- Muon spectrometers (1)
- Muscle function (1)
- Muscle power (1)
- Myb-MuvB (1)
- Myrmica ant non-equilibrium dynamics (1)
- N-heterocyclic olefins (1)
- NAFLD (1)
- NASH (1)
- NCH93 (1)
- NCI-H295R (1)
- NF-Kappa-B (1)
- NF-κB/NFAT reporter cells (1)
- NFATc1 (1)
- NFκB (1)
- NHCs (1)
- NH\(_{3}\) (1)
- NIPAL4 (1)
- NIR OLED (1)
- NLO Computations (1)
- Nanoparticles (1)
- Nasal Carriage (1)
- Necrotizing enterocolitis (1)
- Nectin‐2 (1)
- Neisseria gonorrhoeae (1)
- Neolithic period (1)
- Netherlands (1)
- Neural Differentiation (1)
- Neuroinflammation (1)
- Neuroscience (1)
- Neutrino Detectors and Telescopes (experiments) (1)
- Neutrino Mass (1)
- Nfatc1 (1)
- Nivolumab (1)
- Nonlinear Dynamics (1)
- Non‐ischaemic cardiogenic shock (1)
- Nursing homes (1)
- OSCC (1)
- OSI (1)
- Object recognition (1)
- Oculomotor Muscles/physiology (1)
- Oncology (1)
- Optical spectroscopy (1)
- Oral anticoagulation (1)
- Oscillation (1)
- Outer membrane proteins (1)
- P(P) over-bar collisions (1)
- P-glycoprotein (1)
- P-gp (1)
- PA-flexed view (1)
- PALS (1)
- PCR (1)
- PD-1 (1)
- PD-L1 (1)
- PET/CT (1)
- PP collisions (1)
- PTEN (1)
- Parkinson’s disease (1)
- Particle accelerators (1)
- Particle tracking detectors (Gaseous detectors) (1)
- Particle-acceleration (1)
- Parvovirus (1)
- Pathogenesis (1)
- Pathogens (1)
- Pavlovian-to-instrumental transfer (1)
- Pentixafor (1)
- Personalized medicine (1)
- Pflanzen (1)
- Phase- (1)
- Phenols (1)
- Phosphorylation (1)
- Photic (1)
- Physical activity (1)
- Plant signalling (1)
- Plants (1)
- Polygonum cuspidatum (1)
- Polymer-drug interaction (1)
- Polymers (1)
- Poplars (1)
- Positron annihilation spectroscopy (1)
- Positron-Emission Tomography (1)
- Positronen-Emissions-Tomografie (1)
- Postoperative complications (1)
- Premna (1)
- Preterm birth (1)
- Prevalence (1)
- ProQ (1)
- Prognostic markers (1)
- Prognostic scoring system (1)
- Protein (1)
- Protein folding (1)
- Protein kinase D3 (PKD3) (1)
- Proteus vulgaris (1)
- Proton-Proton Collisions (1)
- Psychiatric disorders (1)
- Psychology (1)
- Psychomotor Performance/physiology (1)
- Pulmonary function tests (1)
- Quality-control (1)
- Quantum electrodynamics (1)
- R package (1)
- RCT (1)
- RNA expression (1)
- RNA metabolism (1)
- RNA-seq (1)
- RNA-seq transcriptome (1)
- RNAi (1)
- RNAlater (1)
- ROR1 (1)
- RSV-A ON1 (1)
- RT-qPCR (1)
- Radiation (1)
- Radiation exposure (1)
- Radiographs (1)
- Radiotherapy (1)
- RapidEye (1)
- Regimes (1)
- Relativistic heavy-ion collisions (1)
- Reminder e-mails (1)
- Remnant RX J1713.7-3946 (1)
- Research Article (1)
- Respiratory tract infection (1)
- Retinopathy (1)
- Rhizomucor (1)
- Rhizopus (1)
- Robotics (1)
- Ruthenium (1)
- Ruxolitinib (1)
- S. aureus (1)
- SASHA (1)
- SB332235 (1)
- SPOT-6 (1)
- SR/mitochondria metabolic feedback (1)
- ST 772 (1)
- ST18 (1)
- SWAT (1)
- SWAT model (1)
- Saccades/physiology (1)
- Salmo trutta fario (1)
- Scarabaeidae (1)
- Scattering (1)
- Scenario analysis (1)
- Screening (1)
- Secondary stroke prevention (1)
- Sediment (1)
- Self-navigation (1)
- Self-renewal (1)
- Sentinel-2 (1)
- Serine proteases (1)
- Serotonin (1)
- Sex chromosome (1)
- Sex determination (1)
- Sexual development and function (1)
- ShMOLLI (1)
- Shell (1)
- Sibling donor (MSD) (1)
- Silver (1)
- Simulation (1)
- Single Molecule Localization Microscopy (SMLM) (1)
- Single-Photon (1)
- Skin (1)
- Skull (1)
- Small interfering RNAs (1)
- Smoking (1)
- Societe Francaise (1)
- Soft tissues (1)
- Solid tumors (1)
- Somites (1)
- Species delimitation (1)
- Specimen grinding (1)
- Spektroskopie (1)
- Staphylococcus aureus (1)
- Staphylococcus aureus USA300 (1)
- Stem cell (1)
- Stem-cell biotechnology (1)
- Stereochemistry (1)
- Stimulation (1)
- Stokes-shifted fluorescence emission (1)
- Strains (1)
- Strange Baryon Production (1)
- Stratigraphy (1)
- Streptococcus agalactiae (1)
- Stroke unit (1)
- Stromal cells (1)
- Structural equation modelling (1)
- Structure elucidation (1)
- Subject (1)
- Subtercola vilae (1)
- Supernova (1)
- Support vector machine (1)
- Supportive therapy (1)
- Surgical and invasive medical procedures (1)
- Surgical oncology (1)
- Survey (1)
- Swine (1)
- Syap1 knockout (1)
- Symmetry (1)
- Systemic sclerosis (1)
- T cell (1)
- T cell receptor (1)
- T cell suppression (1)
- T cells (1)
- T-cell lymphoma (1)
- T1 mapping (1)
- TDDFT (1)
- TDMT (1)
- TEV (1)
- TGFβ/BMP signaling (1)
- TLR2 (1)
- TLR4 (1)
- TNF (1)
- TNF-alpha (1)
- TNFR family costimulatory receptors (1)
- TNFR2 (1)
- TNFR2 agonists (1)
- TNFR2 antagonism (1)
- TNFα (1)
- TNNI3 (1)
- TP53 (1)
- TPCA1 (1)
- TRAF1 (1)
- TRAF2 (1)
- TRAILR1 (1)
- TRAILR2 (1)
- TanDEM-X (1)
- TeV energies (1)
- Temozolomide (1)
- Terramechanics (1)
- Thiotepa-busulfan-fludarabine (TBF) (1)
- Time resolved measurements (1)
- Toddler (1)
- Top quark (1)
- Torque (1)
- Tractography (1)
- Transcription (1)
- Transcription factor NRF1 (1)
- Transcriptomic (1)
- Translation (1)
- Translation Initiation (1)
- Translational research (1)
- Transposable element (1)
- Transverse-Momentum (1)
- Trees (1)
- Tregs (regulatory T cells) (1)
- Triticeae (1)
- Triticum aestivum (1)
- Trousseau's syndrome (1)
- Tubulin (1)
- U-Net (1)
- UV/Vis spectroscopy (1)
- UV–Vis (1)
- Ultrarelativistic Heavy-Ion (1)
- Unrelated donor (UD) (1)
- Ustilago maydis (1)
- V-ATPase (1)
- VLBW (1)
- VMAT (1)
- Valentine Leukocidin Genes (1)
- Valgus osteoarthritis (1)
- Value at Risk (1)
- Vcsels (1)
- View (1)
- Visuo-tactile congruency (1)
- W & Z bosons (1)
- WSS (1)
- Weak-Interactions (1)
- Wheel (1)
- Wire chambers (MWPC, Thin-gap chambers, drift chambers, drift tubes, proportional chambers etc) (1)
- X-ray radiography (1)
- YAP (1)
- Yoga (1)
- Young Adult (1)
- Zebrafish (1)
- Zinc (1)
- ZnO-NP (1)
- [68Ga]Pentixafor (1)
- \(^{177}\)Lu-OPS201 (1)
- abdominal surgery (1)
- absolute bioavailability (1)
- accidents (1)
- accumulation (1)
- accuracy (1)
- acetate (1)
- acid ceramidase (1)
- acid ceramidase inhibitor ceranib-2 (1)
- acoustic radiation force impulse imaging (1)
- acrophobia (1)
- actin (1)
- action control (1)
- activated delayes flourescence (1)
- activation (1)
- active galactic nuclei (1)
- active ingredients (1)
- acute kidney injury (1)
- acute lymphoblastic leukemia (1)
- additive manufacturing (1)
- adenoma (1)
- adenotonsillectromy (1)
- adiposity (1)
- adrenocortical carcinoma (1)
- adult attention deficit/hyperactivity disorder (adult ADHD) (1)
- advanced breast cancer (1)
- aerobic fitness (1)
- affect bursts (1)
- age at onset (1)
- age groups (1)
- age-related macular degeneration (1)
- agriculture (1)
- airway management (1)
- alternative splicing (1)
- altitudinal gradients (1)
- alveolar epithelium (1)
- amphiphilic block copolymer (1)
- amsacrine (1)
- amyloidoma (1)
- amyotrophic lateral sclerosis (1)
- amyotrophic lateral sclerosis (ALS) (1)
- analysis of variance (1)
- anime (1)
- anomaly detection (1)
- anorexia nervosa (1)
- anti-contactin-1 (1)
- anti-depressant drug (1)
- antibacterial (1)
- antibacterial activity (1)
- antibiofilm (1)
- antibiotic resistance (1)
- anticancer (1)
- antifungal (1)
- antitrypanosomal (1)
- anti‐aging (1)
- anxiety generalization (1)
- anxiolytics (1)
- aortocaval fistula model (1)
- appraisal theory of emotion expression (1)
- arctic greening (1)
- arenes (1)
- artificial intelligence (1)
- artificial light at night (1)
- aspergillosis (1)
- asylum seekers (1)
- asylum status (1)
- atmospheric waves (1)
- atrial fibrillation (1)
- auto-planning (1)
- autoantibody (1)
- autobiography (1)
- auxin (1)
- axillary dissection (1)
- bacterial pathogen (1)
- bacterial physiology (1)
- bacteriology (1)
- baghdadite (1)
- balancing trade-offs (1)
- bank mergers (1)
- bariatric surgery (1)
- behavior (1)
- behavioral plasticity (1)
- bench press (1)
- bending strength (1)
- benige tumor (1)
- beta-lactam antibiotics (1)
- biceps tendinitis (1)
- biceps tendon (1)
- big earth data (1)
- bilateral internal carotid artery stenosis (1)
- binary species (1)
- biofabricated vascular graft (1)
- bioinformatics tool (1)
- bioink (1)
- biokinetics (1)
- biological rhythm (1)
- biological techniques (1)
- biomarker (1)
- biomarker signature (1)
- biomaterial ink (1)
- biomechanics (1)
- biomolecular processes (1)
- biotic interaction (1)
- bispecific antobodies (1)
- bisulfite pyrosequencing (1)
- black trout syndrome (1)
- bladder (1)
- blazars (1)
- blinatumoman (1)
- blinking (1)
- blocking phagocytosis (1)
- blood (1)
- blood-cerebrospinal fluid barrier (1)
- bone (1)
- bone adhesive (1)
- bone critical size defect (1)
- bone graft substitutes (1)
- bone marrow stromal cells (1)
- boolean modeling (1)
- boreholes (1)
- borohydrides (1)
- boronate (1)
- boronic acid (1)
- borylenes (1)
- bottom-up processing (1)
- brain (1)
- brain development (1)
- brain disorders (1)
- brain endothelial cell (1)
- brain endothelial cells (1)
- brain networks (1)
- brain plasticity (1)
- brain tumor (1)
- breast cancer (1)
- bridge-to-transplant (1)
- bronchoalveolar lavage fluid (1)
- bronchopulmonary dysplasia (1)
- brown trout (1)
- bullae (1)
- burn severity (1)
- burnt-wood (1)
- calcium (1)
- calcium phosphate (1)
- calnexin (1)
- calving front (1)
- cancer immunotherapy (1)
- cancer metabolism (1)
- carabid beetles (1)
- carbon (1)
- carbon monoxide (1)
- cardiac metabolism (1)
- cardiac remodelling (1)
- cardiac surgery (1)
- cardiolipin (1)
- cardiopulmonary bypass (1)
- cardiovascular genetics (1)
- cardiovascular risk factors (1)
- care (1)
- cartilage repair (1)
- catchment (1)
- catheterization (1)
- catheters (1)
- caveolin-1 (Cav-1) (1)
- cefotiam (1)
- cell biology (1)
- cell differentiation (1)
- cell migration (1)
- cell signalling (1)
- cell therapy (1)
- cell therapy and immunotherapy (1)
- ceramide (1)
- cerebral microbleeds (1)
- cerebrospinal fluid (1)
- cervical dystonia (1)
- channelrhodopsins (1)
- chemokine (1)
- chemokine receptor (1)
- child behavior (1)
- chimeric antigen receptor (1)
- chirality (1)
- chirality-induced spin selectivity (1)
- chlamydia (1)
- chlorophyll fluorescence imaging (1)
- cholesterol (1)
- cholesterol 25 hydroxylase (1)
- cholesteryl ester (1)
- chondrocyte (1)
- chondrogenesis (1)
- chronic kidney disease (CKD) (1)
- chronic non-bacterial osteomyelitis (1)
- circRNA (1)
- circadian rhythm (1)
- circular transcriptome sequencing (1)
- cisplatin (1)
- claudin-5 (1)
- climate extremes (1)
- clinical characteristics (1)
- clinical imaging (1)
- clinical outcome (1)
- clinical trial (1)
- cluster analysis (1)
- co-culture (1)
- coagulation system (1)
- coastline (1)
- cognitive control (1)
- coherence (1)
- coherent risk measures (1)
- cold adaptation (1)
- collagen sponge (1)
- collimator (1)
- collodion baby (1)
- collybistin (1)
- colonization (1)
- common diseases (1)
- comparative genomics (1)
- comparison (1)
- competition (1)
- complement deposition (1)
- complement factor H (1)
- complex DNA damage (1)
- composite material (1)
- composition (1)
- computer-mediated communication (1)
- concealed information test (1)
- conditioning (1)
- congruency sequences (1)
- consensus (1)
- conservation (1)
- constructed trade-offs (1)
- context-based teaching (1)
- contextual fear conditioning (1)
- continuous theta burst stimulation (cTBS) (1)
- continuum limit (1)
- control levels (1)
- convolutional neural network (1)
- copeptin (1)
- coping (1)
- copy number variation (1)
- cortical excitability (1)
- cortical silent period (1)
- count time series (1)
- cristal engeneering (1)
- crop statistics (1)
- cross-coupling (1)
- cross-sectional study (1)
- cryosphere (1)
- cryostructured scaffolds (1)
- curcumin (1)
- curvature (1)
- cuticular permeability (1)
- cyclic compounds (1)
- cyclophosphamide (FLAMSA) (1)
- cytoskeleton (1)
- cytotoxic (1)
- daratumumab (1)
- data warehouse (1)
- dead-wood enrichment (1)
- decay (1)
- deception (1)
- deep learning (1)
- default-interventionist framework (1)
- definition (1)
- dehydrocoupling (1)
- dehydrogenaticve borylation (1)
- democracy (1)
- democracy profiles (1)
- dendritic cell (1)
- depth dose curves (1)
- desk-based (1)
- desmin (1)
- desmin-related myopathy (1)
- desminopathy (1)
- desmoglein (1)
- desmoplastic small round cell tumor (1)
- desmosome (1)
- deubiquitinases (1)
- developmental forms (1)
- dexamethasone (1)
- diabetes (1)
- diacylglycerol (1)
- diacylglycerol (DAG) (1)
- diagnostic markers (1)
- dialysis adequacy (1)
- diazadiborinines (1)
- diboration (1)
- diborenes (1)
- diborynes (1)
- differentiation (1)
- differentiation potential (1)
- diffuse large B-cell lymphoma (1)
- diffusion weighted mri (1)
- digital health (1)
- dimeric peptide (1)
- direct muss spectrometric profiling (1)
- discrete systems (1)
- disease genetics (1)
- dissolution rates (1)
- distractor-response binding (1)
- distributed control (1)
- distributed learning (1)
- distributions (1)
- diversity gradients (1)
- document analysis (1)
- domain-specific language (1)
- donor (1)
- donor-acceptor systems (1)
- dopamine (1)
- dorsal root ganglion (1)
- dosimetry (1)
- double arc (1)
- doxorubicin (1)
- driving simulation (1)
- drought (1)
- drug delivery (1)
- drug release (1)
- drug resistance evolution (1)
- dual setting system (1)
- duchenne muscular dystrophy (1)
- duplication-deficiency (1)
- dyes (1)
- dynamic facial emotion expression (1)
- dystonia (1)
- e(+)e(-) Collisions (1)
- early brain injury (1)
- early-life stress (1)
- earlywood (1)
- eccentric hypertrophy (1)
- ecosystem service (1)
- effective point of measurement (1)
- efficient intervention points (1)
- electrical resistivity tomography (1)
- electrochemistry (1)
- electron-precise diborates (1)
- elementary body (1)
- eletrhydrodynamic (1)
- emission (1)
- emotion enactment (1)
- emotion processing (1)
- emotion recognition (1)
- emotional behavior (1)
- emotions (1)
- emulsions oil-in-water (1)
- en bloc transfer (1)
- enantiomers (1)
- end-stage renal disease (1)
- endocytosis (1)
- endothelin-1 (1)
- endothelium (1)
- endurance (1)
- enercy-richness hypothesis (1)
- energy homeostasis (1)
- enhancer (1)
- environmental justice (1)
- enzyme mechanism (1)
- epidural block (1)
- epithelial-mesenchymal transition (1)
- error estimation (1)
- estimation error (1)
- ethics (1)
- eugenol (1)
- evapotranspiration (1)
- exciton (1)
- exciton-exciton (1)
- exercise intervention (1)
- expansion microscopy (1)
- expected value of control (1)
- extinction (1)
- extinction dynamics (1)
- extracellular domain (1)
- extramedullary hematopoiesis (1)
- extreme phenotypes (1)
- eye movement (1)
- eye movements (1)
- face (1)
- face-voice integration (1)
- faces (1)
- fan culture (1)
- fatigue (1)
- fault detection (1)
- fear (1)
- fear learning (1)
- febrile seizures (1)
- feminist rap (1)
- femoral head (1)
- fertility (1)
- fibre length (1)
- fibromyalgia (1)
- fibrotest (1)
- fission (1)
- flash freezing (1)
- flora (1)
- flourescence quantum yield (1)
- flu-like symptoms (1)
- fluerescence (1)
- fluorenscence (1)
- fluorescent probes (1)
- fluorine (1)
- fluoroarene (1)
- fluorogen-activating RNA aptamer (FLAP) (1)
- fluoroquinolone (1)
- food colorings (1)
- food resources (1)
- foraging patterns (1)
- forensic sample (1)
- forest ecology (1)
- forest fire (1)
- forest management (1)
- forest resources inventory (1)
- formation control (1)
- fractional variability (1)
- fracture (1)
- fragmentation functions (1)
- free choice (1)
- free radical polymerization (1)
- friut fly behaviour (1)
- full arc (1)
- fully convolutional neural networks (1)
- function (1)
- functional MRI (1)
- functional analysis (1)
- functional training (1)
- fungal molecular diagnostics (1)
- fungal rhodopsins (1)
- games (1)
- gangliosides and lipid rafts (1)
- gastric-bypass surgery (1)
- gastrointestinal cancer (1)
- gastrointestinal tract (1)
- gaze control (1)
- gem-bisboronates (1)
- gene alleles (1)
- gene expression analysis (1)
- gene family evolution (1)
- gene regulation (1)
- genetic counselling (1)
- genetic engineering (1)
- genetic recombination (1)
- genome (1)
- genome analysis (1)
- genome-wide association studies (1)
- genomic imprinting (1)
- genotoxicity (1)
- glacier front (1)
- glacier terminus (1)
- glioblastoma multiforme (GBM) (1)
- glioma (1)
- global (1)
- global change (1)
- glucose transporter (1)
- glycine transporter 2 (1)
- glycoprotein Ibα (1)
- glycoprotein VI (1)
- glyvine uptake (1)
- graft vs. host disease (1)
- graft-versus host (1)
- graft-versus-host-disease (1)
- granules (1)
- gravitational waves (1)
- green fluorescence protein (GFP) (1)
- ground penetrating radar (1)
- ground-dwelling predators (1)
- growth (1)
- growth patterns (1)
- growth ring width (1)
- guided bone regeneration (1)
- guideline adherent treatment (1)
- guidelines (1)
- gut–liver axis (1)
- hA<sub>3</sub>AR (1)
- habit (1)
- habit strength (1)
- haematopoietic stem cell (1)
- halogens (1)
- head and neck squamous cell carcinoma (1)
- heart-to-mediastinum ratio (1)
- heat wave (1)
- helical molecules (1)
- helicenes (1)
- hematopoietic stem cell transplantation (1)
- heme oxygenase-1 (1)
- hemicraniectomy (1)
- hemodiafiltration (1)
- hemodialysis (1)
- hemophagocytosis (1)
- hemorrhagic (1)
- hemostasis (1)
- henoch-schönlein purpura (1)
- hepatitis B virus (1)
- hereditary breast and ovarian cancer (1)
- heterotypic scaffold design (1)
- high LET irradiation (1)
- high efficiency (1)
- high risk (1)
- high-resolution tandem mass spectrometry (1)
- hip fracture (1)
- hippocampus (1)
- histological subtype (1)
- histone H2AX (1)
- historical document analysis (1)
- historical printings (1)
- homogeneous catalysis (1)
- homogenization (1)
- honeybee (1)
- honeybees (1)
- hospital exemption (1)
- hospital-acquired methicillin-resistant Staphylococcus aureus (1)
- human adipose-derived stromal cells (1)
- human behaviour (1)
- human cerebral endothelial cells (1)
- human plasma (1)
- human xenografted mouse models (1)
- hybrid fabrication (1)
- hybrid materials (1)
- hydroboration (1)
- hydrological regime (1)
- hydroxyapatite (1)
- hydroxylation (1)
- hyperosmolality (1)
- hyperpersonal communication (1)
- hypertension (1)
- hypothermia (1)
- ichthyosis (1)
- identification (1)
- iliac crest (1)
- illness-death model (1)
- image processing (1)
- imaging (1)
- imaging PAM (1)
- immediate-early gene (1)
- immune evasion (1)
- immunity (1)
- immunotherapy of cancer (1)
- in vitro (1)
- in vitro model (1)
- in vitro models (1)
- incidence (1)
- indole-3-acetic acid (1)
- indolylpyrimidylpiperazines (1)
- infection biology (1)
- infections (1)
- infectious diseases (1)
- inflammatory gene (1)
- information extraction (1)
- inherited cardiomyopathies (1)
- inhibition (1)
- inhibitor (1)
- injection site reactions (1)
- injury (1)
- inmates (1)
- innate immune evasions (1)
- insect abundance (1)
- insect collection (1)
- insurance medicine (1)
- integrative management strategy (1)
- integrin α2 (1)
- intercomparison (1)
- interface (1)
- interferon beta (1)
- interleukin (1)
- interleukin-6 (1)
- intermediate dose Ara-C (1)
- intermediate filaments (1)
- intermittent exercise (1)
- internal carotid artery stenosis (1)
- intersession experiences (1)
- intersession processes (1)
- interval training (1)
- intestine (1)
- intracellular bacterial pathogens (1)
- intracranial bleeding (1)
- invasive aspergillosis (1)
- inventory (1)
- ionization chambers (1)
- ionization energy (1)
- ionization potential (1)
- iron metabolism (1)
- ischemia reperfusion injury (1)
- ischemia time (1)
- jet shapes (1)
- jet stream (1)
- jets (1)
- keratinocytes (1)
- key structure - fluorescence activation relationships (SFARs) (1)
- kidney (1)
- kinesin (1)
- kinesthesia (1)
- lag effect (1)
- land sharing (1)
- land surface (1)
- land use (1)
- language in media (1)
- late onset sepsis (1)
- late positive potential (1)
- lateral process of the talus (1)
- latewood (1)
- leaf width (1)
- library screening (1)
- lichen planus (1)
- lifestyle (1)
- ligand binding (1)
- ligand-receptor promiscuity (1)
- light-emitting-diodes (1)
- lignan (1)
- lineage-specific genes (1)
- linear conversion (1)
- linguistic cues (1)
- linguistic politics (1)
- lipid metabolism (1)
- liponeurocytoma (1)
- liquid biopsy (1)
- liver (1)
- liver metastases (1)
- local field potentials (1)
- logical trade-offs (1)
- long head of biceps tendon (1)
- long-term potentiation (1)
- loss of function (1)
- low-cost photometer (1)
- lowland beech forests (1)
- luminescence (1)
- lung metastases (1)
- lying (1)
- lymph nodes (1)
- lymphohistiocytosis (1)
- lyso-phospholipids (1)
- mAb engineering (1)
- mRNA (1)
- mTOR (1)
- macrophage polarization (1)
- macrophages (1)
- magnesium phosphate cement (1)
- maintenance therapy (1)
- major river basins (1)
- management (1)
- manga (1)
- match load (1)
- maternal separation (1)
- mating (1)
- mating preference (1)
- measurement (1)
- mebendazole (1)
- mechanical performance (1)
- mechanisms of disease (1)
- mechanistic modelling (1)
- medaka (1)
- medical rehabilitation (1)
- medication extraction (1)
- medicinal plant (1)
- medicine (1)
- medieval manuscripts (1)
- medulloblastoma (1)
- melatonin (1)
- melt electrowriting (MEW) (1)
- meningioma (1)
- meningococcal disease (1)
- meningococcus (1)
- mesenchymal stem cell (1)
- mesenchymal stem cells (1)
- mesenchymal stromal cell (1)
- mesentery (1)
- meta-analysis (1)
- metabolic flux (1)
- metabolic modeling (1)
- metabolic modelling (1)
- metabolic switch (1)
- metabolism (1)
- metabolism of infected and uninfected host cells (1)
- metabolomic (1)
- metabolomic profiling (1)
- metal complexenes (1)
- metallo-supramolecular polymer (1)
- metals (1)
- metaproteomics (1)
- metastasis (1)
- metastasis-associated in colon cancer 1 (MACC1) (1)
- methods (1)
- methylation array (1)
- methylprednisolone (1)
- miR-221-5p (1)
- micelles (1)
- micro-chambers (1)
- microbial rhodopsins (1)
- microbial surface component recognising adhesive matrix molecules (1)
- microbiota (1)
- microfilament (1)
- microtubules (1)
- migrant (1)
- minerals (1)
- minimal residual disease (1)
- minipig (1)
- minocycline (1)
- mitochondrial genome (1)
- mitochondrial mRyR1 (1)
- mitofusin 2 (1)
- mitotic genes (1)
- mixed methods (1)
- mobile app (1)
- mobile health intervention (1)
- model-based diagnosis (1)
- molecular biology (1)
- molecular imaging (1)
- molecular neuroscience (1)
- molecular signature (1)
- molecular structures (1)
- molecular subtypes (1)
- monitoring (1)
- monocyte-derived DC (1)
- monotoring (1)
- moonlighting (1)
- motility (1)
- motor-evoked potentials (MEP) (1)
- mouse feeding model (1)
- movement (1)
- mucormycosis (1)
- multi-spectral (1)
- multiresistance (1)
- mutants (1)
- mycophenolic acid (1)
- myelination (1)
- myeloid-derived suppressor cell (MDSC) (1)
- nano-satellite (1)
- nanocomplex (1)
- nanoparticles (1)
- nasal mucosal barrier function (1)
- native populations (1)
- natural language processing (1)
- natural pest control (1)
- naturalistic scenes (1)
- naïve B cells (1)
- necroptosis (1)
- neonatal outcome (1)
- neonates (1)
- nerve injury (1)
- nervous system (1)
- nest microbiota (1)
- neume notation (1)
- neurocytoma (1)
- neurodegenerative disease (1)
- neuroendocrine tumors (1)
- neuromuscular disease (1)
- neuronal (1)
- neuronal apoptosis (1)
- neurooncology (1)
- neuropathic pain (1)
- neurovascular unit (1)
- neutral sphingomyelinase-2 (1)
- neutrinos (1)
- next generation sequencing (1)
- next-generation sequencing (1)
- next-generation-sequencing (1)
- niche (1)
- nicknames (1)
- non-invasive fibrosis assessment (1)
- nonalcoholic fatty liver disease (1)
- noncoding RNA (1)
- noncovalent complex (1)
- noncovalent nanocomplex (1)
- normal distribution (1)
- nu SVR (1)
- nuclear envelope (1)
- nuclear export (1)
- number of (1)
- obesity (1)
- obstructive sleep apnoea (1)
- office environment (1)
- office-workers (1)
- oligodendrocyte (1)
- oncogenes (1)
- oncology (1)
- oncolysis (1)
- oncolytic vaccinia virus (1)
- online dating (1)
- online survey (1)
- ontology (1)
- optical character recognition (1)
- optical music recognition (1)
- optimal drug combination (1)
- optimal drug targeting (1)
- optimal pharmacological modulation (1)
- optimal treatment strategies (1)
- optimization (1)
- optogenetics (1)
- orthoreovirus (1)
- osteochondral defect (1)
- otakuism (1)
- outcome devaluation (1)
- ovarian cancer (1)
- overuse injury (1)
- oxidative DNA damage (1)
- oxidative stress (1)
- oxindole alkaloids (1)
- p-block element (1)
- p21-activated kinase Mbt/PAK4 (1)
- paediatrics (1)
- pain generator (1)
- panel sequencing (1)
- panic disorder (1)
- panniculitis (1)
- paranodopathy (1)
- parasexual recombination (1)
- parent-child relationship (1)
- parental perception (1)
- partial agonists (1)
- partial arc (1)
- passive transfer (1)
- patch-clamp (1)
- pathogenesis (1)
- pathogenic bacteria (1)
- peatland (1)
- pediatrics (1)
- peer review (1)
- pefloxacin (1)
- peginterferon bet-1a (1)
- pemphigus (1)
- penetration bias (1)
- penumbra (1)
- peptide inhibitor design (1)
- peptidomoics (1)
- performativity (1)
- pericytes (1)
- persistence (1)
- person identity processing (1)
- personality judgments (1)
- perylene bisimide (1)
- perylene bisimides (1)
- pesicicles (1)
- pharmacophore map (1)
- phenolic compounds (1)
- phosphorescence (1)
- phosphorescene spectra (1)
- phosphorylation (1)
- photoconductive interlayer (1)
- photodynamic chemotherapy (1)
- photoelectron spectroscopy (1)
- photolysis (1)
- photophysical prosperties (1)
- photophysics (1)
- physical activity (1)
- physical activity promotion (1)
- physical saliency (1)
- phytic acid (1)
- pi-conjugation (1)
- piRNA (1)
- piscine orthoreovirus (1)
- pit membrane diameter (1)
- placebo and nocebo effects (1)
- plan comparison (1)
- plant reproduction (1)
- plant-derived metabolites (1)
- plants (1)
- plant–microbe–pollinator triangle (1)
- plant–pathogen interaction (1)
- plaque cross-sectional area (1)
- plasma membrane (1)
- plasma membrane depolarization (1)
- plasminogen (1)
- platelet (1)
- platelet degranulation (1)
- platelets (1)
- point shear wave elastography (1)
- pointing task (1)
- pol(2-oxazoline) (1)
- polarimetery (1)
- pollination (1)
- pollination network (1)
- poly(2-oxazine) (1)
- poly(2-oxazoline) (1)
- polycaprolactone (1)
- polyglycerol sulfates (1)
- polynomials (1)
- polyphenols (1)
- population genetics (1)
- position estimation (1)
- positron (1)
- positron annihilation lifetime spectroscopy (1)
- post-fire management (1)
- post-translational modification (1)
- posttranscriptional control (1)
- powerlifting (1)
- pre-B (1)
- precision medicine (1)
- predictive markers (1)
- predictive performance (1)
- premature aging (1)
- presynaptic hyperekplexia (1)
- preterm infants (1)
- primary endpoint (1)
- primary healthcare (1)
- primary outcome (1)
- primary vascular smooth muscle‐like cells (vSMCs) (1)
- pro-B (1)
- probe-based real-time PCR (1)
- production machines (1)
- prognosis (1)
- prognostic marker (1)
- proliferation (1)
- proliferative darkening syndrome (1)
- prostate cancer (1)
- protected forests (1)
- protein binding (1)
- protein processing (1)
- protein transport (1)
- protein-bound uremic toxins (1)
- protein-protein interaction (PPI) (1)
- proteomics (1)
- psychological pain modulation (1)
- psychometrics (1)
- psychosocial adaptation (1)
- psychosocial stress (1)
- psychotherapy (1)
- puberty (1)
- pyrolysis (1)
- quality assurance (1)
- quality of democracy (1)
- quality of life (QoL) (1)
- quantile forecasts (1)
- quantitative analysis (1)
- questionnaires (1)
- radiation (1)
- radiation sensitivity (1)
- radical (1)
- radiopacity (1)
- radiotherapy (1)
- ray (1)
- reaction times (1)
- reactive intermediates (1)
- reactive oxygen species (1)
- real life setting (1)
- real world evidence (1)
- reciprocal translocation (1)
- recombinant tissue-type plasminogen activator (1)
- reconstructive surgery (1)
- rectum (1)
- refractory aGvHD (1)
- regulatory T cells (Treg) (1)
- regulatory capital (1)
- regulatory dendritic cells (1)
- reliability (1)
- renal imaging (1)
- repeated sprint (1)
- reprogamming of host cell metabolism (1)
- required hydrophilic–lipophilic balance (1)
- rereading (1)
- resettlement refugees (1)
- resistance (1)
- resonance theory (1)
- restrictive cardiomyopathy (1)
- resveratrol biosynthesis (1)
- retention interval (1)
- reticulate body (1)
- retinal pigment epithelium (1)
- retrospective (1)
- review (1)
- rhBMP–2 (1)
- rheumatoid arthritis (1)
- ring-expansion reactions (1)
- ripk1 (1)
- ripk3 (1)
- risk stratification (1)
- robust control (1)
- ruthenium (1)
- saccades (1)
- sacha inchi oil (1)
- sample storage (1)
- saproxylic organisms (1)
- sarcomere (1)
- satellite formation flying (1)
- satellite remote sensing (1)
- scaffold (1)
- screening (1)
- search (1)
- secondary prevention (1)
- secreted effectors (1)
- segmental progeria (1)
- semantic segmentation (1)
- semileptonic & radiative decays (1)
- sensor data (1)
- sensor supports (1)
- sentinel (1)
- sentinel prey (1)
- sepsis (1)
- sequence analysis (1)
- sequential addition (1)
- serotonin (1)
- serotonin deficiency (1)
- setting reaction (1)
- sex robots (1)
- short-range order (1)
- shoulder (1)
- shoulder pain (1)
- shyness (1)
- sigma boranes (1)
- signal specification (1)
- signalling (1)
- silica supraparticles (1)
- simulation and modeling (1)
- simultaneous presentation paradigm (1)
- single arc (1)
- single photon (1)
- single-molecule tracking (1)
- sirolimus (1)
- skeletal progenitor cells (1)
- skewness (1)
- slope bogs (1)
- small intestinal submucosa scaffold (1)
- small-cell lung cancer (1)
- smart surfaces (1)
- snowboarder's ankle (1)
- snowboarder's fracture (1)
- soccer (football) (1)
- social anxiety disorder (1)
- social attention (1)
- sociophonetics (1)
- sodium (1)
- soft tissue sarcoma (1)
- software (1)
- soil fauna (1)
- solar cells (1)
- solid tumors (1)
- solid-state NMR spectroscopy (1)
- solid-state emitters (1)
- solitary bees (1)
- solubility enhancement (1)
- solvent-dependent fluorescence yield (1)
- somatic mutations (1)
- somatosensory evoked potential (1)
- somatosensory temporal discrimination (1)
- spa typing (1)
- spacing effect (1)
- spatial analyses (1)
- spatial heterogeneity (1)
- spatial scale (1)
- species richness (1)
- species‐area hypothesis (1)
- sphingomyelinase (1)
- sphingosine kinase (1)
- sphingosine kinase inhibitor SKI-II (1)
- sphingosine-1-phosphate (1)
- spin polarization (1)
- spin transport (1)
- spinal muscular atrophy (1)
- spleen (1)
- split renal function (1)
- sporidia (1)
- standing (1)
- starPEG hydrogel (1)
- startle response (1)
- static vs. dynamic faces (1)
- statistical distributions (1)
- statistical models (1)
- steering (1)
- stem Cells (1)
- stem cell transplantation (1)
- stereospecific sythesis (1)
- stereotactic body radiation therapy (1)
- stereotactic irradiation (1)
- steric effects (1)
- steroid-resistant aGvHD (1)
- storage-pool diseases (1)
- strength training (1)
- stress (1)
- stress fiber (1)
- stress tolerance (1)
- stromal vascular fraction (1)
- structural disruption (1)
- structure-activity (1)
- structure-activity relationships (1)
- structured illumination microscopy (1)
- subadditivity (1)
- subarachnoid hemorrhage (1)
- submicroscopic chromosome rearrangement (1)
- subsarcolemmal mitochondria (1)
- substituent (1)
- subsurface hydrology (1)
- subthalamic nucleus (1)
- sulfoimines (1)
- sulfur (1)
- super resolution microscopy (1)
- super-resolution microscopy (1)
- superresolution (1)
- suppressor mutation (1)
- surface transport (1)
- surface water (1)
- surgical and invasive medical procedures (1)
- surgical site infection (1)
- survival analysis (1)
- synchrotron radiation (1)
- synchrotron radiatoren (1)
- synergistic effect (1)
- synthesis (1)
- systematic affiliation (1)
- targeted bisulfite sequencing (1)
- targeted therapies (1)
- targeted therapy (1)
- taxonomy (1)
- temozolomide (1)
- temperature‐mediated resource exploitation hypothesis (1)
- temperature‐richness hypothesis (1)
- temporal discrimination threshold (1)
- temporal lobe epilepsy (1)
- tendon-derived stem cell (1)
- terrestrial LiDAR (1)
- theranostics (1)
- therapy (1)
- therapy response (1)
- thermal remote sensing (1)
- thrombo-inflammation (1)
- thrombosis (1)
- tight junctions (1)
- time lag (1)
- time series (1)
- tisindoline (1)
- top-down processing (1)
- topminnow (1)
- total body irradiation/busulfan (1)
- toxicity (1)
- transcranial magnetic simulation (TMS) (1)
- transcription (1)
- transcription deficiency (1)
- transient dynamics (1)
- transient elastography (1)
- transient ischemic attack (1)
- transient middle cerebral artery occlusion (1)
- transition metal (1)
- transmission (1)
- transplantation (1)
- transposable elements (1)
- tree cavities (1)
- triacylglycerides (1)
- triarylboranes (1)
- triple bonds (1)
- trivalent boron (1)
- trypanosomes (1)
- tryptophan hydroxylase 2 (1)
- tumor burden (1)
- tumor control probability (1)
- tumor heterogeneity (1)
- tumor suppressor miRNA (1)
- tumour-necrosis factors (1)
- two-photon absorption (1)
- tyloses (1)
- type VII secretion system (1)
- ubiquitin ligase (1)
- ubiquitylation (ubiquitination) (1)
- uncanny valley (1)
- uncertainties (1)
- uncertainty (1)
- uneven-aged mountainous (1)
- unmanaged broadleaved forests (1)
- unsaturated fatty acids (1)
- upconversion (1)
- uptake (1)
- urban environments (1)
- uremic toxins (1)
- urinary tract infections (1)
- vaccinia (1)
- variability (1)
- vasculitis (1)
- vertebral body (1)
- vertical and radial variation (1)
- very high energies (VHE) (1)
- very long-chain aliphatic compounds (1)
- vessel lumen diameter (1)
- vestibular schwannoma (1)
- video laryngoscopy (1)
- virotherapy (1)
- virtual isocenter (1)
- viruses (1)
- visual orientation (1)
- visual perception (1)
- visual realism (1)
- vitamin D (1)
- vitamins (1)
- voice-face matching (1)
- volume overload (1)
- walking (1)
- water balance (1)
- watershed (1)
- weightlifting (1)
- well-being (1)
- white matter lesions (1)
- whole-genome duplication (1)
- whole-genome sequencing (1)
- wild bees (1)
- wood anatomy (1)
- work (1)
- work capacity evaluation (1)
- work engagement (1)
- work performance (1)
- wound healing (1)
- youth (1)
- zinc oxide (1)
- zinc oxide nanoparticles (1)
- zonal construct (1)
Institute
- Theodor-Boveri-Institut für Biowissenschaften (72)
- Medizinische Klinik und Poliklinik II (24)
- Physikalisches Institut (24)
- Neurologische Klinik und Poliklinik (22)
- Institut für Psychologie (20)
- Institut für Anorganische Chemie (19)
- Institut für Geographie und Geologie (18)
- Medizinische Klinik und Poliklinik I (17)
- Institut für Hygiene und Mikrobiologie (16)
- Institut für Organische Chemie (16)
Sonstige beteiligte Institutionen
- Department of Hematology and Oncology, Sana Hospital Hof, Hof, Germany (1)
- Department of Laboratory Medicine and Medicine Huddinge, Karolinska Institutet and University Hospital, Stockholm, Sweden (1)
- Department of Medicine A, University Hospital of Münster, Münster, Germany (1)
- IZKF Nachwuchsgruppe Geweberegeneration für muskuloskelettale Erkrankungen (1)
- Interdisciplinary Center for Clinical Research (1)
- Johns Hopkins School of Medicine (1)
- University of Bari Medical School, Bari, Italy (1)
Evolutionary conserved networks of human height identify multiple Mendelian causes of short stature
(2019)
Height is a heritable and highly heterogeneous trait. Short stature affects 3% of the population and in most cases is genetic in origin. After excluding known causes, 67% of affected individuals remain without diagnosis. To identify novel candidate genes for short stature, we performed exome sequencing in 254 unrelated families with short stature of unknown cause and identified variants in 63 candidate genes in 92 (36%) independent families. Based on systematic characterization of variants and functional analysis including expression in chondrocytes, we classified 13 genes as strong candidates. Whereas variants in at least two families were detected for all 13 candidates, two genes had variants in 6 (UBR4) and 8 (LAMA5) families, respectively. To facilitate their characterization, we established a clustered network of 1025 known growth and short stature genes, which yielded 29 significantly enriched clusters, including skeletal system development, appendage development, metabolic processes, and ciliopathy. Eleven of the candidate genes mapped to 21 of these clusters, including CPZ, EDEM3, FBRS, IFT81, KCND1, PLXNA3, RASA3, SLC7A8, UBR4, USP45, and ZFHX3. Fifty additional growth-related candidates we identified await confirmation in other affected families. Our study identifies Mendelian forms of growth retardation as an important component of idiopathic short stature.
Dishevelled (DVL) is the key component of the Wnt signaling pathway. Currently, DVL conformational dynamics under native conditions is unknown. To overcome this limitation, we develop the Fluorescein Arsenical Hairpin Binder- (FlAsH-) based FRET in vivo approach to study DVL conformation in living cells. Using this single-cell FRET approach, we demonstrate that (i) Wnt ligands induce open DVL conformation, (ii) DVL variants that are predominantly open, show more even subcellular localization and more efficient membrane recruitment by Frizzled (FZD) and (iii) Casein kinase 1 ɛ (CK1ɛ) has a key regulatory function in DVL conformational dynamics. In silico modeling and in vitro biophysical methods explain how CK1ɛ-specific phosphorylation events control DVL conformations via modulation of the PDZ domain and its interaction with DVL C-terminus. In summary, our study describes an experimental tool for DVL conformational sampling in living cells and elucidates the essential regulatory role of CK1ɛ in DVL conformational dynamics.
Preclinical studies point to a pivotal role of the orexin 1 (OX1) receptor in arousal and fear learning and therefore suggest the HCRTR1 gene as a prime candidate in panic disorder (PD) with/without agoraphobia (AG), PD/AG treatment response, and PD/AG-related intermediate phenotypes. Here, a multilevel approach was applied to test the non-synonymous HCRTR1 C/T Ile408Val gene variant (rs2271933) for association with PD/AG in two independent case-control samples (total n = 613 cases, 1839 healthy subjects), as an outcome predictor of a six-weeks exposure-based cognitive behavioral therapy (CBT) in PD/AG patients (n = 189), as well as with respect to agoraphobic cognitions (ACQ) (n = 483 patients, n = 2382 healthy subjects), fMRI alerting network activation in healthy subjects (n = 94), and a behavioral avoidance task in PD/AG pre- and post-CBT (n = 271). The HCRTR1 rs2271933 T allele was associated with PD/AG in both samples independently, and in their meta-analysis (p = 4.2 × 10−7), particularly in the female subsample (p = 9.8 × 10−9). T allele carriers displayed a significantly poorer CBT outcome (e.g., Hamilton anxiety rating scale: p = 7.5 × 10−4). The T allele count was linked to higher ACQ sores in PD/AG and healthy subjects, decreased inferior frontal gyrus and increased locus coeruleus activation in the alerting network. Finally, the T allele count was associated with increased pre-CBT exposure avoidance and autonomic arousal as well as decreased post-CBT improvement. In sum, the present results provide converging evidence for an involvement of HCRTR1 gene variation in the etiology of PD/AG and PD/AG-related traits as well as treatment response to CBT, supporting future therapeutic approaches targeting the orexin-related arousal system.
Zinc (Zn2+) can modulate platelet and coagulation activation pathways, including fibrin formation. Here, we studied the (patho)physiological consequences of abnormal platelet Zn2+ storage and release. To visualize Zn2+ storage in human and mouse platelets, the Zn2+ specific fluorescent dye FluoZin3 was used. In resting platelets, the dye transiently accumulated into distinct cytosolic puncta, which were lost upon platelet activation. Platelets isolated from Unc13d−/− mice, characterized by combined defects of α/δ granular release, showed a markedly impaired Zn2+ release upon activation. Platelets from Nbeal2−/− mice mimicking Gray platelet syndrome (GPS), characterized by primarily loss of the α-granule content, had strongly reduced Zn2+ levels, which was also confirmed in primary megakaryocytes. In human platelets isolated from patients with GPS, Hermansky-Pudlak Syndrome (HPS) and Storage Pool Disease (SPD) altered Zn2+ homeostasis was detected. In turbidity and flow based assays, platelet-dependent fibrin formation was impaired in both Nbeal2−/− and Unc13d−/− mice, and the impairment could be partially restored by extracellular Zn2+. Altogether, we conclude that the release of ionic Zn2+ store from secretory granules upon platelet activation contributes to the procoagulant role of Zn2+ in platelet-dependent fibrin formation.
B cell development in bone marrow is a precisely regulated complex process. Through successive stages of differentiation, which are regulated by a multitude of signaling pathways and an array of lineage-specific transcription factors, the common lymphoid progenitors ultimately give rise to mature B cells. Similar to early thymocyte development in the thymus, early B cell development in bone marrow is critically dependent on IL-7 signaling. During this IL-7-dependent stage of differentiation, several transcription factors, such as E2A, EBF1, and Pax5, among others, play indispensable roles in B lineage specification and maintenance. Although recent studies have implicated several other transcription factors in B cell development, the role of NFATc1 in early B cell developmental stages is not known. Here, using multiple gene-manipulated mouse models and applying various experimental methods, we show that NFATc1 activity is vital for early B cell differentiation. Lack of NFATc1 activity in pro-B cells suppresses EBF1 expression, impairs immunoglobulin gene rearrangement, and thereby preBCR formation, resulting in defective B cell development. Overall, deficiency in NFATc1 activity arrested the pro-B cell transition to the pre-B cell stage, leading to severe B cell lymphopenia. Our findings suggest that, along with other transcription factors, NFATc1 is a critical component of the signaling mechanism that facilitates early B cell differentiation.
Genome-wide association studies (GWAS) have identified more than 170 breast cancer susceptibility loci. Here we hypothesize that some risk-associated variants might act in non-breast tissues, specifically adipose tissue and immune cells from blood and spleen. Using expression quantitative trait loci (eQTL) reported in these tissues, we identify 26 previously unreported, likely target genes of overall breast cancer risk variants, and 17 for estrogen receptor (ER)-negative breast cancer, several with a known immune function. We determine the directional effect of gene expression on disease risk measured based on single and multiple eQTL. In addition, using a gene-based test of association that considers eQTL from multiple tissues, we identify seven (and four) regions with variants associated with overall (and ER-negative) breast cancer risk, which were not reported in previous GWAS. Further investigation of the function of the implicated genes in breast and immune cells may provide insights into the etiology of breast cancer.
The mechanisms behind carbon dioxide (CO2) dependency in non-autotrophic bacterial isolates are unclear. Here we show that the Staphylococcus aureus mpsAB operon, known to play a role in membrane potential generation, is crucial for growth at atmospheric CO2 levels. The genes mpsAB can complement an Escherichia coli carbonic anhydrase (CA) mutant, and CA from E. coli can complement the S. aureus delta-mpsABC mutant. In comparison with the wild type, S. aureus mps mutants produce less hemolytic toxin and are less virulent in animal models of infection. Homologs of mpsA and mpsB are widespread among bacteria and are often found adjacent to each other on the genome. We propose that MpsAB represents a dissolved inorganic carbon transporter, or bicarbonate concentrating system, possibly acting as a sodium bicarbonate cotransporter.
The NEDD8-activating enzyme (NAE) inhibitor MLN4924 inhibits cullin-RING ubiquitin ligase complexes including the SKP1-cullin-F-box E3 ligase βTrCP. MLN4924 therefore inhibits also the βTrCP-dependent activation of the classical and the alternative NFĸB pathway. In this work, we found that a subgroup of multiple myeloma cell lines (e.g., RPMI-8226, MM.1S, KMS-12BM) and about half of the primary myeloma samples tested are sensitized to TNF-induced cell death by MLN4924. This correlated with MLN4924-mediated inhibition of TNF-induced activation of the classical NFκB pathway and reduced the efficacy of TNF-induced TNFR1 signaling complex formation. Interestingly, binding studies revealed a straightforward correlation between cell surface TNFR1 expression in multiple myeloma cell lines and their sensitivity for MLN4924/TNF-induced cell death. The cell surface expression levels of TNFR1 in the investigated MM cell lines largely correlated with TNFR1 mRNA expression. This suggests that the variable levels of cell surface expression of TNFR1 in myeloma cell lines are decisive for TNF/MLN4924 sensitivity. Indeed, introduction of TNFR1 into TNFR1-negative TNF/MLN4924-resistant KMS-11BM cells, was sufficient to sensitize this cell line for TNF/MLN4924-induced cell death. Thus, MLN4924 might be especially effective in myeloma patients with TNFR1+ myeloma cells and a TNFhigh tumor microenvironment.
Fanconi anemia (FA) is a genetically heterogeneous disorder with 22 disease-causing genes reported to date. In some FA genes, monoallelic mutations have been found to be associated with breast cancer risk, while the risk associations of others remain unknown. The gene for FA type C, FANCC, has been proposed as a breast cancer susceptibility gene based on epidemiological and sequencing studies. We used the Oncoarray project to genotype two truncating FANCC variants (p.R185X and p.R548X) in 64,760 breast cancer cases and 49,793 controls of European descent. FANCC mutations were observed in 25 cases (14 with p.R185X, 11 with p.R548X) and 26 controls (18 with p.R185X, 8 with p.R548X). There was no evidence of an association with the risk of breast cancer, neither overall (odds ratio 0.77, 95%CI 0.44–1.33, p = 0.4) nor by histology, hormone receptor status, age or family history. We conclude that the breast cancer risk association of these two FANCC variants, if any, is much smaller than for BRCA1, BRCA2 or PALB2 mutations. If this applies to all truncating variants in FANCC it would suggest there are differences between FA genes in their roles on breast cancer risk and demonstrates the merit of large consortia for clarifying risk associations of rare variants.
Surgical extrusion is a recognised treatment option for teeth that have insufficient coronal tooth structure remaining due to deep caries, resorption or traumatic injury. However, the technique has not been widely adopted, arguably because extraction of a severely compromised tooth may be difficult to achieve in a gentle and predictable way. In this paper, we present our novel approach to surgical extrusion and subsequent management of teeth using a vertical extraction system (Benex), which has become the method of choice in the authors' practice for many teeth that would otherwise be deemed unrestorable. We describe the clinical procedure in detail and discuss the advantages and disadvantages compared to alternative approaches, including surgical crown lengthening and orthodontic extrusion.