Refine
Has Fulltext
- yes (366)
Is part of the Bibliography
- yes (366) (remove)
Year of publication
Document Type
- Journal article (237)
- Doctoral Thesis (113)
- Preprint (14)
- Book article / Book chapter (1)
- Report (1)
Language
- English (366) (remove)
Keywords
- Organische Chemie (68)
- Supramolekulare Chemie (21)
- Selbstorganisation (18)
- self-assembly (16)
- Farbstoff (13)
- perylene bisimide (13)
- fluorescence (12)
- water oxidation (12)
- Merocyanine (11)
- RNA (11)
- Fluoreszenz (10)
- Perylenbisimid (10)
- Perylenderivate (10)
- Aggregation (9)
- supramolecular chemistry (9)
- Chemie (8)
- Elektronentransfer (8)
- photocatalysis (8)
- SARS-CoV-2 (7)
- polycyclic aromatic hydrocarbons (7)
- Squaraine (6)
- catalysis (6)
- dyes (6)
- in vitro selection (6)
- organic chemistry (6)
- Chemische Synthese (5)
- Chromophor (5)
- Exziton (5)
- Katalyse (5)
- Nucleinsäuren (5)
- Self-assembly (5)
- dyes/pigments (5)
- energy transfer (5)
- luminescence (5)
- DNA (4)
- Flüssigkristall (4)
- Ladungstransfer (4)
- Metallosupramolekulare Chemie (4)
- NMR-Spektroskopie (4)
- Naphthylisochinolinalkaloide (4)
- Perylenbisdicarboximide <Perylen-3,4:9,10-bis(dicarboximide)> (4)
- Perylene Bisimide (4)
- Polymere (4)
- Ruthenium complexes (4)
- Supramolekulare Struktur (4)
- Wasseroxidation (4)
- aggregation (4)
- boranes (4)
- chemistry (4)
- chirality (4)
- circular dichroism (4)
- exciton coupling (4)
- liquid crystals (4)
- macrocycles (4)
- organic solar cells (4)
- photoinduced electron transfer (4)
- ruthenium complexes (4)
- sphingolipids (4)
- structure elucidation (4)
- transient absorption (4)
- Aggregat <Chemie> (3)
- Ancistrocladaceae (3)
- C-C coupling (3)
- Chirality (3)
- Chiralität <Chemie> (3)
- DNS (3)
- Deoxyribozymes (3)
- Energietransfer (3)
- Fluorescence (3)
- Fotokatalyse (3)
- Hydrogel (3)
- Merocyanin (3)
- Quantenchemie (3)
- RNA modification (3)
- Ruthenium Komplexe (3)
- Selbstassemblierung (3)
- Self-Assembly (3)
- Triarylamine (3)
- Wasser (3)
- X-ray crystallography (3)
- absolute configuration (3)
- aromaticity (3)
- artificial photosynthesis (3)
- cell imaging (3)
- ceramide (3)
- ceramides (3)
- deoxyribozymes (3)
- electron transfer (3)
- homogeneous catalysis (3)
- kinetics (3)
- merocyanines (3)
- metallosupramolecular chemistry (3)
- molecular docking (3)
- naphthylisoquinoline alkaloids (3)
- non-covalent interactions (3)
- organic photodiodes (3)
- organische Solarzelle (3)
- pentacene (3)
- spectroscopy (3)
- transient absorption spectroscopy (3)
- triarylamine (3)
- 10-bis(dicarboximide)> (2)
- 4:9 (2)
- Ancistrocladus (2)
- Anorganische Chemie (2)
- Aptamer (2)
- Aromatically annulated triquinacenes (2)
- Aromatisch anellierte Triquinacene (2)
- Chili RNA Aptamer (2)
- Chiralität (2)
- Click-Chemie (2)
- Corannulene (2)
- Design (2)
- Dyade (2)
- Dyes (2)
- Energy Transfer (2)
- Epitranscriptomics (2)
- Exciton coupling (2)
- Exzitonenkopplung (2)
- FRET (2)
- Fluoreszenz-Resonanz-Energie-Transfer (2)
- G-quadruplexes (2)
- Gold (2)
- Guanidinderivate (2)
- Holothuria spinifera (2)
- J- and H-Aggregate (2)
- J- and H-Aggregates (2)
- J‐aggregates (2)
- LC-HRESIMS (2)
- Liquid Crystal (2)
- Merocyanine dyes (2)
- Methyltransferase (2)
- Molekulare Erkennung (2)
- Nucleoside (2)
- Oligomere (2)
- Organic Chemistry (2)
- Organische Solarzelle (2)
- Organische Synthese (2)
- Organischer Feldeffekttransistor (2)
- Organischer Halbleiter (2)
- Oxidation (2)
- Perylenbisdicarboximide (2)
- Perylenbisdicarboximide <Perylen-3 (2)
- Perylenbisimide (2)
- Perylene bisimide (2)
- Photochemistry (2)
- Photosensibilisator (2)
- Polycyclische Aromaten (2)
- Pyrene (2)
- RNA Enzymes (2)
- RNA labeling (2)
- RNA-dependent RNA polymerase (2)
- RNS (2)
- Ringöffnungspolymerisation (2)
- Rutheniumkomplexe (2)
- Scheibe-Aggregat (2)
- Selbstassoziation (2)
- Spinchemie (2)
- Strukturaufklärung (2)
- Supramolecular Chemistry (2)
- Transiente Absorption (2)
- Triarylamin (2)
- Triquinacenderivate (2)
- UV/Vis spectroscopy (2)
- Wasserstoffbrückenbindung (2)
- Wirt-Gast-Beziehung (2)
- XNA (2)
- absorption (2)
- acid sphingomyelinase (2)
- annulation (2)
- azulene (2)
- boron (2)
- boronate esters (2)
- cage compounds (2)
- cerebrosides (2)
- charge separation (2)
- charge transfer (2)
- chirality transfer (2)
- click chemistry (2)
- cooperativity (2)
- corannulene (2)
- crystal engineering (2)
- curved hydrocarbons (2)
- cyclophane (2)
- cyclophanes (2)
- cytotoxic activity (2)
- cytotoxicity (2)
- density functional calculations (2)
- dimer (2)
- dynamic covalent chemistry (2)
- electrocatalysis (2)
- epitranscriptomics (2)
- fullerenes (2)
- gekrümmte Kohlenwasserstoffe (2)
- helicenes (2)
- heterogeneous catalysis (2)
- homogenous catalysis (2)
- hydrogen bonding (2)
- intervalence charge transfer (2)
- ligands (2)
- lysosome (2)
- macrocycle (2)
- marine natural product (2)
- mechanism (2)
- nanographene (2)
- naphthalene diimide (2)
- nicht-kovalente Wechselwirkungen (2)
- oligothiophenes (2)
- optical spectroscopy (2)
- organic semiconductors (2)
- organic solar cell (2)
- perylene bisimides (2)
- phosphorescence (2)
- polymer-peptide-conjugate (2)
- polymerization (2)
- polymers (2)
- redox cascade (2)
- renewable fuels (2)
- ribozymes (2)
- ruthenium (2)
- ruthenium bda complexes (2)
- self-sorting (2)
- singlet oxygen (2)
- site-specific RNA cleavage (2)
- solid-state emitters (2)
- solvent effects (2)
- spin chemistry (2)
- squaraine dyes (2)
- stereochemistry (2)
- streptomyces (2)
- supramolekulare Chemie (2)
- thermodynamics (2)
- thiol-ene (2)
- triplet (2)
- triquinacene derivatives (2)
- two-photon absorption (2)
- two-photon excited fluorescence (2)
- water (2)
- water splitting (2)
- "steepest descent-modest ascent" (1)
- "steilsten Abstieg - schwächste Aufstieg" (1)
- (bi)pyridine-based ligand (1)
- 2"-> (1)
- 2':6' (1)
- 2-photon absorption (1)
- 5'-O-Methyldioncophylline D (1)
- A-D-A dyes (1)
- A. abbreviatus (1)
- A. likoko (1)
- ADME analysis (1)
- AIE (1)
- API (1)
- Absolute Configuration (1)
- Absolute Konfiguration (1)
- Absorption (1)
- Acenes (1)
- Acetylneuraminsäure <N-> (1)
- Actinomyceten (1)
- Actinomycetes (1)
- Adsorption (1)
- Aggregate (1)
- Akzeptor <Chemie> (1)
- Aldehyde Bioconjugation (1)
- Alkaloid (1)
- Alkaloide (1)
- Alkoxylradikale (1)
- Alkoxylradikals (1)
- Alkyltransferase Ribozyme SAMURI (1)
- Alzheimer′s disease (1)
- Aminosäuren (1)
- Amphiphile Verbindungen (1)
- Amplification (1)
- Analysis of RNA Modifications (1)
- Anchimeric assistance in solvolysis (1)
- Ancistrocladus ealaensis (1)
- Ancistrocladus likoko (1)
- Ancistrolikokine E3 (1)
- Anode (1)
- Anti-infectious activity (1)
- Antiausterity activity (1)
- Antimalariamittel (1)
- Antimicrobial activities (1)
- Antimicrobial proteins (1)
- Antimikrobielle Aktivitäten (1)
- Antimikrobieller Wirkstoff (1)
- Antitumor-Antibiotikum (1)
- Antitumor-antibitioc (1)
- Antiviral nucleoside analogues (1)
- Apoptosis (1)
- Arene-Fluoroarene (1)
- Aromatic-hydrocarbon (1)
- Artificial Base Pair (1)
- Aspergillus niger (1)
- Asymmetric synthesis (1)
- Asymmetrische Synthese (1)
- Atomic and molecular interactions with photons (1)
- Atropisomere (1)
- Atropisomerie (1)
- BMP-2 (1)
- BMP-2 delivery (1)
- Bacillus megaterium (1)
- Baltic Sea (1)
- Barbituric Acid Merocyanines (1)
- Base pairing (1)
- Basenpaarung (1)
- Bicyclo[1.1.0]butylcarbinyl sulfonates (1)
- Biochemistry (1)
- Biocompatibility (1)
- Biodegradable polymer scaffolds (1)
- Biomaterial (1)
- Bioorganic chemistry (1)
- Bioorganik (1)
- Bioorthogonal (1)
- Bioorthogonal Tag (1)
- Biradikal (1)
- Bodipy (1)
- Bola-Amphiphil (1)
- Bone morphogenetic protein-2 (1)
- Bone tissue engineering (1)
- Bor-Stickstoff-Verbindungen (1)
- Borane (1)
- Boron-Nitrogen Dative Bond (1)
- Butadien (1)
- C-13 NMR (1)
- CCL2 (MCP-1) (1)
- CD-Spektroskopie (1)
- CD4+ T cells (1)
- CD8+ T cells (1)
- COVID-19 (1)
- CXCL8 (IL-8) (1)
- Caco-2 (1)
- Cage (1)
- Calix[4]aren (1)
- Carbazolderivate (1)
- Carbon (1)
- Carboxylat-Rezeptor (1)
- Catalysis (1)
- Ceramide (1)
- Charge-transfer-Komplexe (1)
- Chemical modification (1)
- Chemische Bindung (1)
- Chemische Reaktion (1)
- Chemosensor (1)
- Chirality Transfer (1)
- Chlorin (1)
- Chlorinderivate (1)
- Chromophore (1)
- Chromophore Assembly (1)
- Chromophores (1)
- Circular Dichroism (1)
- Circular dichroism (1)
- Circular-Dichroismus (1)
- Co-Crystal Structures of Chili RNA (1)
- Computational chemistry (1)
- Computerchemie (1)
- Congo (1)
- Congolese Ancistrocladus plants (1)
- Conjugated polymers (1)
- Coordination Polymer (1)
- Coronaviren (1)
- Covalent Organic Framework (1)
- Crosslinker (1)
- Crosslinking (1)
- Cryoelectron Microscopy (1)
- Cryoelectron microscopy (1)
- Crystal structure of MTR1 (1)
- Cyaninfarbstoff (1)
- Cyclic peptides (1)
- Cyclobutylcarbinyl sulfonates (1)
- Cyclooctine (1)
- Cyclooctyne (1)
- Cyclophan (1)
- Cyclovoltammetrie (1)
- DNA catalysis (1)
- DNA catalyst (1)
- DNA-based nanostructures (1)
- DNA-processing enzymes (1)
- DNA/RNA binding (1)
- DNA/RNA sensors (1)
- DNS-Schädigung (1)
- DOSY-NMR (1)
- Demethylase (1)
- Demethylierung (1)
- Demokratische Republik Kongo (1)
- Deoxyribozyme (1)
- Diamant (1)
- Diarylethen (1)
- Diarylethene (1)
- Diarylethylene (1)
- Dicarboximide (1)
- Dicarboximides (1)
- Dichtebestimmung in Theorie und Experiment (1)
- Dictyota (1)
- Dictyotaceae (1)
- Dihydrooxazole (1)
- Dimer (1)
- Dimer-Konfiguration (1)
- Dimere (1)
- Dimeric Naphthylisoquinoline Alkaloids (1)
- Dimers (1)
- Dioncophylline C (1)
- Donator <Chemie> (1)
- Donor (1)
- Donor-Akzeptor Triaden (1)
- Donor-Photosensibilisator-Akzeptor Triade (1)
- Donor−acceptor dyads (1)
- Drug Delivery System (1)
- Dyad (1)
- Dye (1)
- Dyes/pigments (1)
- Dünnschichttransistor (1)
- EPR (1)
- EPR spectroscopy (1)
- Effectors in plant pathology (1)
- Electron (1)
- Electron Transfer (1)
- Electron demand in ditosylates (1)
- Electron density (1)
- Electron transfer (1)
- Elektrochemie (1)
- Elektronendichte (1)
- Elektronendichtebestimmung (1)
- Elektronenspinresonanzspektroskopie (1)
- Emission (1)
- Energieaufnahme (1)
- Energietransfer <Mikrophysik> (1)
- Energy transfer (1)
- Enzym (1)
- Enzymes (1)
- Enzyminhibitor (1)
- Epitranskriptom (1)
- Eriodictyon californicum (1)
- Excitons (1)
- FT-IR spectroscopy (1)
- Farbstoffe (1)
- Farbstoffe/Pigmente (1)
- Festkörper-NMR (1)
- Festphasensynthese (1)
- Fiels-effect transistors (1)
- Fluorescence and Crosslinking (1)
- Fluoreszenzaktivierung (1)
- Fluoreszenzresonanz-Energietransfer (1)
- Fluoreszenzspektrometer (1)
- Fluoreszenzspektroskopie (1)
- Fluorogenic RNA Aptamers (1)
- Foldamers (1)
- Fulleren-Netzwerk (1)
- Fullerene (1)
- Functional nucleic acids (1)
- Functionalization (1)
- Fungal host response (1)
- Funktionalisierung <Chemie> (1)
- Funktionelle Polymere (1)
- Galectine (1)
- Garcinia biflavonoids (1)
- Gelieren (1)
- Gibbs activation energy (1)
- Glucosyltransferasen (1)
- Glycoengineering (1)
- Glycosyltransferase (1)
- Gold Nanoparticles (1)
- Gold Nanopartikel (1)
- Golgi (1)
- Graphene nanoribbons (1)
- Growth; BMP-2 (1)
- Grün fluoreszierendes Protein (1)
- Guanidiniocarbonylpyrrol (1)
- H-Aggregate (1)
- H-bonds (1)
- H2A histone family member X (H2AX) (1)
- HIV (1)
- HRMS (1)
- Halbleiter (1)
- Hekate (1)
- Helicene (1)
- Helicene diimide (1)
- Helicität <Chemie> (1)
- Helix- and Zick-Zack-Konformere (1)
- Helix- and Zig-Zag-Conformers (1)
- Helix-Coil-Transition (1)
- Helix-Knäuel-Umwandlung (1)
- Heterosolarzelle (1)
- Hexaarylbenzene (1)
- Hexaarylbenzole (1)
- High efficiency (1)
- High performance (1)
- High-Throughput Sequencing Method, DZ-seq (1)
- Higher-order Transient Absorption Spectroscopy (1)
- Host-Guest Chemistry (1)
- Host-Guest-Chemistry (1)
- Hydrogen bond (1)
- Hyperfine coupling constants (1)
- In-vitro (1)
- Indirect and direct contributions to A<sub>iso</sub> (1)
- Influence of excitation classes (1)
- Inhibitor (1)
- Intensity (1)
- Intermolecular Interactions (1)
- Intermolekulare Wechselwirkungen (1)
- Intervalenzladungstransfer (1)
- Iridium-Photosensibilisator (1)
- Iridiumkomplexe (1)
- Isolation (1)
- Isolierung (1)
- Isolierung <Chemie> (1)
- Isomorphe Nukleobasen-Analoga (1)
- J-Aggregat (1)
- J-Aggregate (1)
- J-Aggregates (1)
- J-aggregate (1)
- J-aggregate behavior (1)
- J-aggregates (1)
- Jozimine A2 (1)
- Jurkat cells (1)
- K-region (1)
- K2–K model (1)
- Kinetic Self-assembly (1)
- Kinetik (1)
- Kohlenhydrate (1)
- Kohlenstoff (1)
- Kohn-Sham Orbitale (1)
- Kohn-Sham Orbitals (1)
- Kolloidalstabilität (1)
- Kombinatorische Synthese (1)
- Komplexierung (1)
- Konfiguration <Chemie> (1)
- Konformeren (1)
- Konglomerat (1)
- Kongo (1)
- Kooperativität (1)
- Koordinationspolymer (1)
- Koordinationspolymere (1)
- Kraftfeld (1)
- Kupplungsreaktion (1)
- Käfigverbindungen (1)
- Ladungstrennung (1)
- Lebende Polymerisation (1)
- Lectins (1)
- Leitfähige Polymere (1)
- Lichtabsorption (1)
- Lichtsammelsystem (1)
- Ligand (1)
- Light-emitting diodes (1)
- Lippert–Mataga plot (1)
- Liquid Crystals (1)
- Liquid-crystalline (1)
- Living Polymerisation (1)
- Lower Critical Solution Temperature (LCST) (1)
- MAS (1)
- METTL8 (1)
- MRCI (1)
- Magnetfeldeffekt (1)
- Makrocyclische Verbindungen (1)
- Makrozyklus (1)
- Mandibular continuity defects (1)
- Marcus inverted region (1)
- Marrow stromal cells (1)
- Mechanismus (1)
- Merocyanine dye (1)
- Mesenchymal transition (1)
- Mesogen (1)
- Metabolismus (1)
- Metaheuristik-Suchmethoden (1)
- Metall-Ion (1)
- Metallosupramolecular chemistry (1)
- Methylierung (1)
- Methyltransferase Ribozyme (1)
- Methyltransferase Ribozyme MTR1 (1)
- Michael addition (1)
- Michael-Addition (1)
- Microenvironment (1)
- Mitochondrial Matrix Protein (1)
- Modified Nucleotides in tRNAs (1)
- Molecular dynamics (1)
- Molecular mechanism (1)
- Molecular probes (1)
- Molecular-dynamics (1)
- Molecules (1)
- Molekül (1)
- Moleküldynamik (1)
- Moleküloptimierung (1)
- Moller-Plesset (1)
- Molnupiravir (1)
- Molnupiravir-Induced RNA Mutagenesis Mechanism (1)
- Monoschicht (1)
- Mulliken-Hush (1)
- Multi Reference (1)
- Multibranched structures (1)
- Multireferenz (1)
- N-acetyllactosamine (1)
- N-oleoyl serinol (1)
- N6-methyladenosine (1)
- N6-methyladenosine (m6A) (1)
- NDI-H (1)
- NIQs (1)
- NIR OLED (1)
- NIR chromophore (1)
- NMR spectroscopy (1)
- Nanodiamant (1)
- Nanopartikel (1)
- Nanoribbon (1)
- Nanosegregation (1)
- Nanostructure (1)
- Nanostrukturen (1)
- Naphthalinbisimid (1)
- Naphthochinonen (1)
- Naphthoquinones (1)
- Naphthyl Isoquinolines (1)
- Naphthylisochinoline (1)
- Naphthylisoindolinone alkaloids (1)
- Naphthylisoquinolin (1)
- Naphthylisoquinoline (1)
- Naphthylisoquinoline alkaloids (1)
- Natural Products (1)
- Natural products (1)
- Naturstoffe (1)
- Neisseria (1)
- Nicht-Fulleren Akzeptor (1)
- Non-Fullerene Acceptor (1)
- Non-linear optics (1)
- Nonlinear Optical Properties of Organic Materials (1)
- Nucleic Acids (1)
- Nucleic acids (1)
- Nucleobase Analogue (1)
- Nucleobase Surrogate Incorporation (1)
- Nucleosidanaloga (1)
- Nukleinsäure (1)
- OEG chains (1)
- OFETs (1)
- OLC (1)
- OLED (1)
- Octavalen (1)
- Oligofructoside (1)
- Oligomers and Polymers (1)
- Oligonucleotide (1)
- Onbead-Enzymscreening (1)
- One-photon (1)
- Optical Spectroscopy (1)
- Optical properties (1)
- Optical spectroscopy (1)
- Optimierungsmethoden (1)
- Optimization methods (1)
- Oral squamous cell carcinoma (1)
- Organelles (1)
- Organic Field-Effect Transistor (1)
- Organic field-effect transistor (1)
- Organic semiconductors (1)
- Organische Halbleiter (1)
- PBI cyclophane (1)
- PEDOT (1)
- PI stacking (1)
- PNA (1)
- Pancreatic cancer (1)
- Paracyclophane (1)
- Pathway (1)
- Pentacen (1)
- Peptid-Nucleinsäuren (1)
- Peptidsynthese (1)
- Perovskite (1)
- Perylen-Farbstoffe (1)
- Perylenbisanhydrid (1)
- Perylenbisimiden (1)
- Perylenbisimides (1)
- Perylene Bisimides (1)
- Perylentetracarbonsäurederivate (1)
- Pflanzenzelle (1)
- Pflanzenzellkulturen (1)
- Phaeophyceae (1)
- Phosphoramidite (1)
- Phosphorylase (1)
- Photochemie (1)
- Photochromie (1)
- Photoconductivity (1)
- Photoelektron (1)
- Photoresponsive DNA Crosslinker (1)
- Phytochemical investigations of a Congolese Ancistrocladus Liana (1)
- Phytochemie (1)
- Plant cell cultures (1)
- Polyamin (1)
- Polycarbazole (1)
- Polycyclic aromatic hydrocarbons (1)
- Polymer (1)
- Polymer-drug interaction (1)
- Polymerhalbleiter (1)
- Polymerkomplexe (1)
- Polymerlösung (1)
- Polymers (1)
- Polymorphismus (1)
- Porosität (1)
- Porous Materials (1)
- Porphyrin (1)
- Potential-energy curves (1)
- Protease (1)
- Protein Corona (1)
- Proteinadsorption (1)
- Proteinen mit antimikrobieller Wirkung (1)
- Protonen-NMR-Spektroskopie (1)
- Protonenreduktion (1)
- Pyren (1)
- Pyrenderivate (1)
- QM/MM (1)
- Quadruplex-DNS (1)
- Quality assessment of antimalarial medicines from the Congo (1)
- Quantenchemische Rechnungen (1)
- Quantifizierung (1)
- Quantum Chemical CD Calculations (1)
- Quantum Chemical Calculations (1)
- Quantum mechanics / molecular modeling (1)
- Quasi-Newton-Verfahren (1)
- RAFT (1)
- RNA Aptamer (1)
- RNA G-quadruplex (1)
- RNA Labelling (1)
- RNA Methyltransferase (1)
- RNA Modification (1)
- RNA aptamers (1)
- RNA cleavage (1)
- RNA ligation (1)
- RNA modifications (1)
- RNA splicing (1)
- RNA structures (1)
- RNA-Aptamere (1)
- RNA-Cleaving Deoxyribozymes (1)
- RNA-Dependent RNA Polymerase (1)
- RNA-catalyzed RNA methylation (1)
- RU-(II) complexes (1)
- Radical-ion pair (1)
- Raman (1)
- Raumfüllung (1)
- Rearrangement of carbocations (1)
- Redox-Kaskade (1)
- Redoxkaskade (1)
- Redoxreaktion (1)
- Reduction (1)
- Remdesivir (1)
- Reticular Chemistry (1)
- Ribozym (1)
- Ribozyme (1)
- Ribozyme-catalyzed RNA labeling (1)
- Ribozymes (1)
- Ring closing metathesis (1)
- Ringschlussmetathese (1)
- Rotation (1)
- Ru(II)–Fe(II)–Ru(II) complex (1)
- Ruthenium (1)
- Ruthenium-Photosensibilisator (1)
- Räumliche Anordnung (1)
- Röntgendiffraktometrie (1)
- SARS (1)
- SARS-CoV-2 polymerase (1)
- SARS-CoV2 Replication Impairment (1)
- SELEX (1)
- SERS (1)
- SIB (1)
- SacB (1)
- Scleractinia (1)
- Screening (1)
- Second coordination sphere engineering (1)
- Self-Assembly in Water (1)
- Self-Sortierung (1)
- Sialic acids (1)
- Sialinsäuren (1)
- Simulations (1)
- Single-molecule microscopy (1)
- Sinus floor augmentation (1)
- Site-Specific RNA Cleavage (1)
- Site-specific RNA labelling (1)
- Solid-State NMR Spectroscopy (1)
- Solution-state NMR (1)
- Sonogashira (1)
- Sonogashira-Hagihara-Reaktion (1)
- Space filling (1)
- Spectroscopy (1)
- Speicher <Informatik> (1)
- Spektroelektrochemie (1)
- Spermin (1)
- Spin density (1)
- Spin flip (1)
- Spin labels (1)
- Spin-Sonde (1)
- Spin-chemistry (1)
- Squamous-cell carcinoma (1)
- Squarain Farbstoffe (1)
- Squaraine Dyes (1)
- Sracking (1)
- Stacking (1)
- Staphylococcus aureus (1)
- State (1)
- Stereochemistry (1)
- Stokes-Verschiebung (1)
- Stokes-shifted fluorescence emission (1)
- Streptomyces axinellae (1)
- Structural Biology (1)
- Structural elucidation (1)
- Structure elucidation (1)
- Struktursonden (1)
- Stylissa carteri (1)
- Suc1 (1)
- Supercap (1)
- Superkondensator (1)
- Supramolecular Block Copolymers (1)
- Supramolecular Element (1)
- Supramolecular Interaction (1)
- Supramolecular aggregates (1)
- Supramolecular electronics (1)
- Supramolekulare Aggregate (1)
- Suzuki coupling (1)
- Synthese (1)
- Synthesediamant (1)
- Synthetic Functional RNAs (1)
- Synthetischer Farbstoff (1)
- Systems (1)
- TD-DFT (1)
- TERRA RNA (1)
- Tabusuche (1)
- Targeting (1)
- Taxol (1)
- Terpyridinderivate <2 (1)
- Terrylenbisimid (1)
- Terrylenderivate (1)
- Terrylene bisimide (1)
- Thalassodendron ciliatum (1)
- Theoretical Chemistry (1)
- Theoretische Charakterisierung (1)
- Theoretische Chemie (1)
- Theorie (1)
- Thermodynamics (1)
- Thiophen (1)
- Tiplet emiters (1)
- Tiplett Emitter (1)
- Tolane-Modified Fluorescent Nucleosides (1)
- Total Synthesis (1)
- Totalsynthese (1)
- Triad (1)
- Triplett (1)
- Tumorigenicity (1)
- Two-photon absorption (1)
- UV-VIS-Spektroskopie (1)
- UV/Vis-Absorption (1)
- Ultrafast spectroscopy (1)
- Vergleich (1)
- Vesikel (1)
- Vibronic contributions (1)
- Wasserlösliche Polymere (1)
- Wasseroxidationsreaktion (1)
- Wasserspaltung (1)
- Wasserstoffbrücken (1)
- Water (1)
- Water Oxidation (1)
- Wirkmechanismus (1)
- Wirkstoff-Träger-System (1)
- Wirt-Gast-Komplex-Chemie (1)
- X-Ray Diffraction (1)
- X-ray Crystallography (1)
- X-ray diffraction (1)
- XRPD (1)
- Xanthin (1)
- YTH reader proteins (1)
- Zelladhäsion (1)
- Zellkultur (1)
- Zinc Chlorin (1)
- Zink (1)
- Zinkchlorine (1)
- Zweidimensionale NMR-Spektroskopie (1)
- Zweiphotonenabsorption (1)
- [FeFe] hydrogenase mimic (1)
- [FeFe]-Hydrogenase Imitator (1)
- [n]helicenes (1)
- \(\alpha\)-phase (1)
- \(\beta\)-phase (1)
- \(^{1}\)H-\(^{13}\)C HETCOR (1)
- abietane (1)
- acceptor (1)
- activating transcription factor 4 (ATF4) (1)
- adsorption (1)
- aelf-assembly (1)
- alkaloids (1)
- alkaloids-Quinoid (1)
- alkene-alkyne [2+2] photocycloaddition (1)
- amodiaquine (1)
- amphiphilic dyes (1)
- amplification (1)
- ancistrocladinium A (1)
- angeregte Zustände (1)
- annihilation (1)
- anti-cancer-agent (1)
- anti-depressant drug (1)
- anti-trypanosomal (1)
- antibacterial activity (1)
- antidepressants (1)
- antimicrobials (1)
- aqua material (1)
- aqueous medium (1)
- arene-fluoroarene (1)
- arenes (1)
- artemether - lumefantrine (1)
- artificial base pair (1)
- association (1)
- ataxia teleagiectasia mutated (ATM) (1)
- atomic mutagenesis (1)
- atropisomer (1)
- azaborole (1)
- azaphilone (1)
- azido-ceramides (1)
- bacterial infection (1)
- bartalinia robillardoides (1)
- biflavanoids (1)
- bile salt (1)
- bioactive compound (1)
- bioactivities (1)
- biocatalysis (1)
- biocompatibility (1)
- biological techniques (1)
- biomass (1)
- bioorthogonal SAM analogue ProSeDMA (1)
- bioorthogonal metabolic glycoengineering; click chemistry; sialic acid (1)
- biophysical investigation (1)
- biosynthesis (1)
- biradical (1)
- bis-terpyridyl ligands (1)
- bola-amphiphile (1)
- boric acid (1)
- boronateesters (1)
- borylation (1)
- brown seaweeds (1)
- bulk-heterojunction solar cells (1)
- calix[4]arene (1)
- capillary zone electrophoresis (1)
- carbohydrate chemistry (1)
- carbon (1)
- carboxylate receptor (1)
- carrier transport (1)
- cascade reactions (1)
- catalyst (1)
- catalyst synthesis (1)
- catalysts (1)
- catalytic (1)
- catalytic DNA (1)
- catalytic activity (1)
- catalytic mechanisms (1)
- cell membrane model (1)
- cellular stress response (1)
- ceramidase (1)
- ceramide analogs (1)
- cerebroside (1)
- ceriops decandra (1)
- charge recombination (1)
- charge transport (1)
- charge transport; hydrogen bonding; oligothiophene; organogel; self-assembly (1)
- charge-separated state (1)
- chemical modification (1)
- chiral resolution (1)
- chlorin (1)
- circular polarized luminescence (1)
- circularly polarized luminescence (1)
- co-aggregation (1)
- cocrystallization (1)
- colloid (1)
- columnar phases (1)
- complexation (1)
- complexity (1)
- computational chemistry (1)
- configurational stability (1)
- conformational search (1)
- conjugated molecule (1)
- conjugation (1)
- cooperative (1)
- cooperative self-assembly (1)
- coordination chemistry (1)
- coordination oligomer (1)
- coordination oligomers (1)
- coordination polymer (1)
- covalent and site-specific RNA labeling (1)
- covalent organic framework (1)
- covalent organic frameworks (1)
- cristal engeneering (1)
- crystalline (1)
- crystals (1)
- curcumin (1)
- curvature (1)
- curved π-systems (1)
- cyclic perylene bisimide (1)
- cyclic trimer (1)
- cyclic voltammetry (1)
- cyclische Trimere (1)
- cyclodehydrogenation (1)
- cylindrical micelles (1)
- cysteine protease (1)
- cytoplasm (1)
- decandrinin (1)
- demethylase enzymes FTO and ALKBH5 (1)
- deracemization (1)
- di-\(\pi\)-methane rearrangement (1)
- diamond (1)
- dibenzosemibullvalenes (1)
- dicarboximide (1)
- differential scanning calorimetry (1)
- diffusion (1)
- diketopyrrolopyrroles (1)
- dimerer Naphthylisochinolin-Alkaloide (1)
- dimerization (1)
- dimers (1)
- dinuclear (1)
- dipolar aggregation (1)
- dipole-dipole interaction (1)
- discotic liquid crystals (1)
- discovery (1)
- dissolution rates (1)
- disulfide bonds (1)
- docking (1)
- docking studies (1)
- domain shift (1)
- donor-acceptor dyad (1)
- donor-acceptor dyads (1)
- donor-acceptor interactions (1)
- donor-acceptor triads (1)
- donor-photosensibilisator-acceptor triad (1)
- donor–acceptor (1)
- donor–acceptor dyads (1)
- drug delivery (1)
- drugs (1)
- duplex structure (1)
- dyad (1)
- dyads (1)
- dye (1)
- dye assembly (1)
- dye chemistry (1)
- electrodes (1)
- electron density (1)
- electronic and spintronic devices (1)
- electronic collective variables (1)
- electronic devices (1)
- electronic structure (1)
- electronic wavefunction (1)
- emission (1)
- enantiomerization (1)
- enantiomers (1)
- energy transfer dynamics (1)
- enzyme (1)
- enzyme engineering (1)
- enzyme purification (1)
- enzyme structure (1)
- enzymes (1)
- ergosterol derivative (1)
- ethenoanthracenes (1)
- excimer (1)
- excimer formation (1)
- excited states (1)
- exciton dynamics (1)
- excitonic chirality (1)
- experimental and theoretical determination of electron density (1)
- extractives (1)
- ferroelectrics (1)
- films (1)
- flavenoids (1)
- flavonoids (1)
- flourescence quantum yield (1)
- fluerescence (1)
- fluorenscence (1)
- fluorescence resonance energy transfer (1)
- fluorescence spectroscopy (1)
- fluorescent (1)
- fluorescent probes (1)
- fluorescent protein (1)
- fluorescent resonance energy transfer (1)
- fluorogen-activating RNA aptamer (FLAP) (1)
- fluoxetine (1)
- flux (1)
- folda-dimer (1)
- folded macrocyles (1)
- folding (1)
- folding landscapes (1)
- force field (1)
- fullerene network (1)
- functional dyes (1)
- functionalization (1)
- galectin-1 (1)
- global minimum (1)
- glycocalyx (1)
- glycosphingolipids (1)
- gold (1)
- growth (1)
- guanidiniocarbonyl pyrrole (1)
- guttiferae (1)
- hMSC-TERT (1)
- halbleitende Polymere (1)
- halichondria panicea (1)
- heavy metals (1)
- helicene (1)
- heterocycles (1)
- hexaarylbenzenes (1)
- hexakisadducts (1)
- high-temperature NMR (1)
- homochiral dimer (1)
- host-guest (1)
- host-guest chemistry (1)
- host-guest systems (1)
- hybrid materials (1)
- hydrazone (1)
- hydrocarbons (1)
- hydrogel (1)
- hydrogen bond (1)
- hydrogen peroxide (1)
- hydroxylation (1)
- imaging (1)
- imidization (1)
- impurity profiling (1)
- in vitro Selection (1)
- in vitro selection from a structured RNA library (1)
- induced phase transition (1)
- inflammation (1)
- inherent chirality (1)
- inhibitor (1)
- intermolecular applications of ribozymes (1)
- intersystem crossing (1)
- intervalence charge-transfer (1)
- intrinsic free space (1)
- invasion (1)
- inflammatory response (1)
- ion pairing (1)
- iridium complex (1)
- iridium photosensitizer (1)
- iron oxide nanoparticles (1)
- isomorphic nucleobase analog (1)
- isotropic hyper fine coupling (1)
- key structure - fluorescence activation relationships (SFARs) (1)
- ladungsgetrennte Zustände (1)
- large Stokes shift (1)
- large stokes shift (1)
- laser (1)
- lectin (1)
- ligand binding (1)
- light harvesting (1)
- light-induced interstrand DNA crosslinking (1)
- liposome (1)
- liquid crystal alignment (1)
- liquid crystal (1)
- livingstonei (1)
- low-valent compounds (1)
- magnetic field effect (1)
- major depression (1)
- marine bacteria (1)
- marine fungi (1)
- marine macroalgae (1)
- marine natural products (1)
- marine sponge (1)
- materials (1)
- materials design (1)
- measles (1)
- merocyanine (1)
- merocyanine dye (1)
- merocyanine dyes/pigments (1)
- mesogens (1)
- metabolic analysis (1)
- metabolic glycoengineering (1)
- metabolism (1)
- metadynamics (1)
- metaheuristic methods (1)
- metal complexenes (1)
- metal-ion-ligand coordination (1)
- metal-to-ligand charge transfer (MLCT) (1)
- metallomacrocycles (1)
- metallosupramolecular π-amphiphiles (1)
- methyl viologen (1)
- methyltransferase (1)
- micelles (1)
- microbiology (1)
- microbiology techniques (1)
- microscopy (1)
- migration (1)
- minimal inhibitory concentration (1)
- mobility (1)
- mode of action (1)
- modified RNA nucleotides (1)
- modified monosaccharides (1)
- modified nucleosides (1)
- molecular (1)
- molecular capsules (1)
- molecular dynamics (1)
- molecular recognition (1)
- molecules (1)
- molekulare Erkennung (1)
- multichromophoric arrays (1)
- multiflora (1)
- multimetallic complexes (1)
- multiple myeloma (1)
- n-type semiconductors (1)
- nanomaterials (1)
- nanoparticles (1)
- nanorods and nanosheets (1)
- nanoscale imaging (1)
- nanosegregation (1)
- nanotube (1)
- naphthylisoquinoline alkaloid (1)
- narrow bandwidth (1)
- natural products (1)
- near infrared chirality (1)
- near infrared emitter (1)
- near-IR chromophores (1)
- near-infrared sensitivity (1)
- neutral polyradical (1)
- neutrales Polyradikal (1)
- non-fullerene acceptor (1)
- non-fullerene acceptors (1)
- noncovalent interactions (1)
- nonfullerene acceptors (1)
- nucleation elongation (1)
- nucleation-elongation (1)
- nucleation-elongation model (1)
- nucleic acid (1)
- nucleic acids (1)
- nucleoside modification recognition (1)
- null-aggregate (1)
- obstructive pulmonary disease (1)
- oligo(phenylene ethynylene) (OPE) (1)
- oligomers (1)
- oligothiophene (1)
- on surface self-assembly (1)
- onbead enzym screening (1)
- optical materials (1)
- optical properties (1)
- optics (1)
- optische Eigenschaften (1)
- organic semiconductors (1)
- organic compounds (1)
- organic light emitting diodes (1)
- organic photovoltaics (1)
- organic semiconductor (1)
- organic transistor (1)
- organische Photovoltaik (1)
- organische Solarzellen (1)
- organischer Feldeffekttransistor (1)
- organischer Transitor (1)
- organization (1)
- organogelator (1)
- orylation (1)
- oxidation (1)
- oxygen reduction reaction (1)
- pancreatic cancer (1)
- parallel polar dimers (1)
- pentaketide (1)
- peptide backbone (1)
- perylene (1)
- perylene bisimide dimers (1)
- perylene bisimide dyes (1)
- perylene bisimide hydrogels (1)
- perylene bismide dye (1)
- perylene dyes (1)
- perylene imide (1)
- perylenebisimide (1)
- perylenebisimide dyes (1)
- phenazine (1)
- phenylboronate (1)
- phosphodiesterase-4 inhibitor (1)
- photochemical (1)
- photoconductive interlayer (1)
- photoinduzierter Elektronentransfer (1)
- photoluminescence (1)
- photophysics (1)
- photosenitizers (1)
- photosensitization (1)
- phthalocyanines (1)
- pi-pi Wechselwirkungen (1)
- pi-pi- stacking (1)
- platinum complexes (1)
- pol(2-oxazoline) (1)
- polar solution (1)
- polare Lösung (1)
- polarizing optical microscopy (1)
- poly(2-oxazine) (1)
- poly(2-oxazoline)s (1)
- polyamine (1)
- polycarbazole (1)
- polycycles (1)
- polycyclic aromatic hydrocarbon (1)
- polyglycidol (1)
- polymer drug interaction (1)
- polymorphism (1)
- polyoxazolines (1)
- polypyridyl complexes (1)
- porous materials (1)
- porousmaterials (1)
- porphyrins (1)
- position-specific installation of m1A in RNA (1)
- probes (1)
- protease (1)
- protease inhibition (1)
- proteasome inhibitor resistance (1)
- proteasome subunit beta type-5 (PSMB5) (1)
- protein adsorption (1)
- protein crystallography (1)
- protein-ligand-interaction (1)
- proton reduction (1)
- push–pull thienylthiazole (1)
- pyrene (1)
- quantenchemische Berechnungen (1)
- quantum chemical analysis (1)
- quantum optics (1)
- quaterrylene bisimide (1)
- quercetin (1)
- rBAM2-labeled RNA strands (1)
- racemization (1)
- radical (1)
- radical anion (1)
- radical ion pair (1)
- reabsorption (1)
- real-time NMR spectroscopy (1)
- recombinant proteins (1)
- redox (1)
- regulatory T cells (1)
- regulatory T cells (Treg) (1)
- renew-able fuels (1)
- resveratrol (1)
- rhizophoraceae (1)
- rigidification (1)
- ring opening polymerisation (1)
- ring-opening polymerization (1)
- rofumilast (1)
- room-temperature phosphorescence (RTP) (1)
- rotation (1)
- rotational diffusion (1)
- ruthenium catalysts (1)
- ruthenium photosensitizer (1)
- sSupramolecular interaction (1)
- scanning probe microscopy (1)
- seagrass (1)
- seco-NIQs-Naphthylisoindolinone (1)
- selbst organisierende Monolagen (SAM) (1)
- selbstaggregierten (1)
- self-assembled monolayer (SAM) (1)
- semiconducting polymers (1)
- separation techniques (1)
- shape-amphiphiles (1)
- short-range JCT-coupling (1)
- short-range order (1)
- sialic acids (1)
- simulated intestinal fluid (1)
- single crystal structure (1)
- site-specific RNA labeling (1)
- social self‐sorting (1)
- solar cells (1)
- solar fuels (1)
- solid-state NMR (1)
- solid-state NMR spectroscopy (1)
- solid-state emitter (1)
- solid‐state emission (1)
- solubility (1)
- solvatochromism (1)
- solvolysis of (1)
- spacer-controlled self-assembly (1)
- spectroscopic analysis (1)
- spermine (1)
- sphingolipid expansion microscopy (1)
- sphingomyelinase (1)
- sphingosine (1)
- sphingosine 1-phosphate (1)
- sphingosine kinases (1)
- spin relaxation (1)
- squaraine polymer (1)
- stability (1)
- star-shaped compounds (1)
- starazine (1)
- starphene analogue (1)
- stereospecific sythesis (1)
- sterubin (1)
- stokes shift (1)
- structural biology (1)
- structural changes (1)
- structural dynamics (1)
- structural elucidation (1)
- structural restriction (1)
- structure probes (1)
- structure probing (1)
- structure–function relation (1)
- structure–property relation (1)
- subphthalocyanine (1)
- substandard and falsified medicines from the Congo (1)
- sucrose phosphorylase (1)
- superparamagnetism (1)
- superstructure (1)
- supramolecular (1)
- supramolecular assembly (1)
- supramolecular folding (1)
- supramolecular materials (1)
- supramolecular polymerization (1)
- supramolecular polymers (1)
- supramolekular (1)
- supramolekularen Elektronik (1)
- surface interactions (1)
- survival (1)
- sustainable energy source (1)
- swallow-tail (1)
- synthesis (1)
- systems (1)
- template catalysis (1)
- tenofovir (1)
- tethya aurantium (1)
- tetracoordinated boron (1)
- tetromycin (1)
- theoretical characterisation (1)
- theoretical investigations (1)
- theoretische Untersuchungen (1)
- theranostics (1)
- thin film transistor (1)
- thin-film transistors (1)
- time-resolved impulsive stimulated raman spectroscopy (1)
- tissue engineering (1)
- topological analysis (1)
- topologische Analyse (1)
- trans-acting 2'-5' adenylyl transferase ribozymes (1)
- transiente Absorption (1)
- transiente Absorptionsspektroskopie (1)
- triaryalmine (1)
- triarylborane (1)
- trinuclear (1)
- triplet sensitization (1)
- two-dimensional nanostructures (1)
- umbrella-shaped mesogens (1)
- upconversion (1)
- upramolecular polymerization process (1)
- vacuum processable (1)
- vesicle (1)
- vibrational coherence (1)
- viral epidemiology (1)
- viral infection (1)
- water oxidation catalysis (1)
- water oxidation reation (1)
- xanthine (1)
- zooxanthellae (1)
- zyklische Peptide (1)
- π-conjugated systems (1)
- π-extension (1)
- π-π-interactions (1)
- π–π Stacking (1)
Institute
- Institut für Organische Chemie (366) (remove)
Schriftenreihe
Sonstige beteiligte Institutionen
- International Max Planck Research School Molecular Biology, University of Göttingen, Germany (2)
- Agricultural Center, BASF SE, 67117 Limburgerhof, Germany (1)
- Center for Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), Göttingen, Germany (1)
- Center for Nanosystems Chemistry (1)
- Center for Nanosystems Chemistry (CNC), University of Würzburg (1)
- Center for Nanosystems Chemistry (CNC), Universität Würzburg, Am Hubland, 97074 Würzburg, Germany (1)
- Charles University, Faculty of Mathematics and Physics, Ke Karlovu 5, 121 16 Prague, Czech Republic (1)
- Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells, Göttingen (1)
- Department of Cellular Biochemistry, University Medical Center Göttingen (1)
- Department of Cellular Biochemistry, University Medical Centre Göttingen (1)
The present thesis adress the synthesis and characterization of novel COFs that contain dye molecules as integral components of the organic backbone. These chromophore-containing frameworks open new research lines in the field and call for the exploration of applications such as catalysis, sensing, or in optoelectronic devices. Initially, the fabrication of organic-inorganic composites by the growth of DPP TAPP COF around functionalized iron oxide nanoparticles is reported. By varying the ratio between inorganic nanoparticles and organic COFs, optoelectronic properties of the materials are adjusted. The document also reports the synthesis of a novel boron dipyrromethene-containing (BODIPY) COF. Synthesis, full characterization and the scope of potential applications with a focus on environmental remediation are discussed in detail. Last, a novel diketopyrrolopyrrole-containing (DPP) DPP-Py-COF based on the combination of DDP and pyrene building blocks is presented. The very low bandgap of these materials and initial investigations on the photosensitizing properties are discussed.
In this thesis, intermolecular acceptor-acceptor interactions in organic solar cells based on new non-fullerene acceptors are addressed. For this purpose, first the reproducibility of organic electronic devices was tested on a new facility for their fabrication. This was followed by the screening for new acceptor materials. Based on this, three molecular systems were investigated with regard to their acceptor-acceptor interactions and their influence on solar cell efficiency.
Site-specific introduction of biorthogonal handles into RNAs is in high demand for decorating RNAs with fluorophores, affinity labels or other modifications. Aldehydes represent attractive functional groups for post-synthetic bioconjugation reactions. Here, we report a ribozyme-based method for the synthesis of aldehyde-functionalized RNA by directly converting a purine nucleobase. Using the methyltransferase ribozyme MTR1 as an alkyltransferase, the reaction is initiated by site-specific N1 benzylation of purine, followed by nucleophilic ring opening and spontaneous hydrolysis under mild conditions to yield a 5-amino-4-formylimidazole residue in good yields. The modified nucleotide is accessible to aldehyde-reactive probes, as demonstrated by the conjugation of biotin or fluorescent dyes to short synthetic RNAs and tRNA transcripts. Upon fluorogenic condensation with a 2,3,3-trimethylindole, a novel hemicyanine chromophore was generated directly on the RNA. This work expands the MTR1 ribozyme’s area of application from a methyltransferase to a tool for site-specific late-stage functionalization of RNA.
The solvatochromic behavior of two donor-π bridge-acceptor (D-π-A) compounds based on the 2-(3-boryl-2-thienyl)thiazole π-linker and indandione acceptor moiety are investigated. DFT/TD-DFT calculations were performed in combination with steady-state absorption and emission measurements, along with electrochemical studies, to elucidate the effect of two different strongly electron-donating hydrazonyl units on the solvatochromic and fluorescence behavior of these compounds. The Lippert–Mataga equation was used to estimate the change in dipole moments (Δµ) between ground and excited states based on the measured spectroscopic properties in solvents of varying polarity with the data being supported by theoretical studies. The two asymmetrical D-π-A molecules feature strong solvatochromic shifts in fluorescence of up to ~4300 cm\(^{−1}\) and a concomitant change of the emission color from yellow to red. These changes were accompanied by an increase in Stokes shift to reach values as large as ~5700–5800 cm\(^{−1}\). Quantum yields of ca. 0.75 could be observed for the N,N-dimethylhydrazonyl derivative in nonpolar solvents, which gradually decreased along with increasing solvent polarity, as opposed to the consistently reduced values obtained for the N,N-diphenylhydrazonyl derivative of up to ca. 0.20 in nonpolar solvents. These two push–pull molecules are contrasted with a structurally similar acceptor-π bridge-acceptor (A-π-A) compound.
A fine balance of regulatory (T\(_{reg}\)) and conventional CD4\(^+\) T cells (T\(_{conv}\)) is required to prevent harmful immune responses, while at the same time ensuring the development of protective immunity against pathogens. As for many cellular processes, sphingolipid metabolism also crucially modulates the T\(_{reg}\)/T\(_{conv}\) balance. However, our understanding of how sphingolipid metabolism is involved in T cell biology is still evolving and a better characterization of the tools at hand is required to advance the field. Therefore, we established a reductionist liposomal membrane model system to imitate the plasma membrane of mouse T\(_{reg}\) and T\(_{conv}\) with regards to their ceramide content. We found that the capacity of membranes to incorporate externally added azide-functionalized ceramide positively correlated with the ceramide content of the liposomes. Moreover, we studied the impact of the different liposomal preparations on primary mouse splenocytes in vitro. The addition of liposomes to resting, but not activated, splenocytes maintained viability with liposomes containing high amounts of C\(_{16}\)-ceramide being most efficient. Our data thus suggest that differences in ceramide post-incorporation into T\(_{reg}\) and T\(_{conv}\) reflect differences in the ceramide content of cellular membranes.
Multichromophoric macrocycles and cyclophanes are important supramolecular architectures for the elucidation of interchromophoric interactions originating from precise spatial organization. Herein, by combining an axially chiral binaphthol bisimide (BBI) and a bay-substituted conformationally labile twisted perylene bisimide (PBI) within a cyclophane of well-defined geometry, we report a chiral PBI hetero-cyclophane (BBI-PBI) that shows intramolecular energy and solvent-regulated chirality transfer from the BBI to the PBI subunit. Excellent spectral overlap and spatial arrangement of BBI and PBI lead to efficient excitation energy transfer and subsequent PBI emission with high quantum yield (80–98 %) in various solvents. In contrast, chirality transfer is strongly dependent on the respective solvent as revealed by circular dichroism (CD) spectroscopy. The combination of energy and chirality transfer affords a bright red circularly polarized luminescence (CPL) from the PBI chromophore by excitation of BBI.
Although solid-state nuclear magnetic resonance (NMR) is a versatile analytical tool to study polymorphs and phase transitions of pharmaceutical molecules and products, this work summarizes examples of spontaneous and unexpected (and unwanted) structural rearrangements and phase transitions (amorphous-to-crystalline and crystalline-to-crystalline) under magic angle spinning (MAS) conditions, some of them clearly being due to the pressure experienced by the samples. It is widely known that such changes can often be detected by X-ray powder diffraction (XRPD); here, the capability of solid-state NMR experiments with a special focus on \(^{1}\)H-\(^{13}\)C frequency-switched Lee–Goldburg heteronuclear correlation (FSLG HETCOR)/MAS NMR experiments to detect even subtle changes on a molecular level not observable by conventional 1D NMR experiments or XRPD is presented. Furthermore, it is shown that a polymorphic impurity combined with MAS can induce a crystalline-to-crystalline phase transition. This showcases that solid-state NMR is not always noninvasive and such changes upon MAS should be considered in particular when compounds are studied over longer time spans.
The pseudopeptide backbone provided by N-(2-aminoethyl)-glycine oligomers with attached nucleobases has been widely utilized in peptide nucleic acids (PNAs) as DNA mimics. Here we demonstrate the suitability of this backbone for the formation of structurally defined dye stacks. Toward this goal a series of peptide merocyanine (PMC) dye oligomers connected to a N-(2-aminoethyl)-glycine backbone were prepared through peptide synthesis. Our concentration-, temperature- and solvent-dependent UV/Vis absorption studies show that under the control of dipole–dipole interactions, smaller-sized oligomers consisting of one, two or three dyes self-assemble into defined duplex structures containing two up to six chromophores. In contrast, upon further extension of the oligomer, the chosen peptide backbone cannot direct the formation of a defined duplex architecture anymore due to intramolecular aggregation between the dyes. For all aggregate species a moderate aggregation-induced emission enhancement is observed.
In π-conjugated organic photovoltaic materials, an excimer state has been generally regarded as a trap state which hinders efficient excitation energy transport. But despite wide investigations of the excimer for overcoming the undesirable energy loss, the understanding of the relationship between the structure of the excimer in stacked organic compounds and its properties remains elusive. Here, we present the landscape of structural dynamics from the excimer formation to its relaxation in a co-facially stacked archetypical perylene bisimide folda-dimer using ultrafast time-domain Raman spectroscopy. We directly captured vibrational snapshots illustrating the ultrafast structural evolution triggering the excimer formation along the interchromophore coordinate on the complex excited-state potential surfaces and following evolution into a relaxed excimer state. Not only does this work showcase the ultrafast structural dynamics necessary for the excimer formation and control of excimer characteristics but also provides important criteria for designing the π-conjugated organic molecules.
Herein we devise and execute a new synthesis of a pristine boron-doped nanographene. Our target boron-doped nanographene was designed based on DFT calculations to possess a low LUMO energy level and a narrow band gap derived from its precise geometry and B-doping arrangement. Our synthesis of this target, a doubly B-doped hexabenzopentacene (B\(_{2}\)-HBP), employs six net C−H borylations of an alkene, comprising consecutive hydroboration/electrophilic borylation/dehydrogenation and BBr\(_{3}\)/AlCl\(_{3}\)/2,6-dichloropyridine-mediated C−H borylation steps. As predicted by our calculations, B\(_{2}\)-HBP absorbs strongly in the visible region and emits in the NIR up to 1150 nm in o-dichlorobenzene solutions. Furthermore, B\(_{2}\)-HBP possesses a very low LUMO level, showing two reversible reductions at −1.00 V and −1.17 V vs. Fc\(^{+}\)/Fc. Our methodology is surprisingly selective despite its implementation of unfunctionalized precursors and offers a new approach to the synthesis of pristine B-doped polycyclic aromatic hydrocarbons.
Designing highly efficient purely organic phosphors at room temperature remains a challenge because of fast non-radiative processes and slow intersystem crossing (ISC) rates. The majority of them emit only single component phosphorescence. Herein, we have prepared 3 isomers (o, m, p-bromophenyl)-bis(2,6-dimethylphenyl)boranes. Among the 3 isomers (o-, m- and p-BrTAB) synthesized, the ortho-one is the only one which shows dual phosphorescence, with a short lifetime of 0.8 ms and a long lifetime of 234 ms in the crystalline state at room temperature. Based on theoretical calculations and crystal structure analysis of o-BrTAB, the short lifetime component is ascribed to the T\(^M_1\) state of the monomer which emits the higher energy phosphorescence. The long-lived, lower energy phosphorescence emission is attributed to the T\(^A_1\) state of an aggregate, with multiple intermolecular interactions existing in crystalline o-BrTAB inhibiting nonradiative decay and stabilizing the triplet states efficiently.
Boric acid (BA) has been used as a transparent glass matrix for optical materials for over 100 years. However, recently, apparent room-temperature phosphorescence (RTP) from BA (crystalline and powder states) was reported (Zheng et al., Angew. Chem. Int. Ed. 2021, 60, 9500) when irradiated at 280 nm under ambient conditions. We suspected that RTP from their BA sample was induced by an unidentified impurity. Our experimental results show that pure BA synthesized from B(OMe)\(_{3}\) does not luminesce in the solid state when irradiated at 250–400 nm, while commercial BA indeed (faintly) luminesces. Our theoretical calculations show that neither individual BA molecules nor aggregates would absorb light at >175 nm, and we observe no absorption of solid pure BA experimentally at >200 nm. Therefore, it is not possible for pure BA to be excited at >250 nm even in the solid state. Thus, pure BA does not display RTP, whereas trace impurities can induce RTP.
Activating Organic Phosphorescence via Heavy Metal–π Interaction Induced Intersystem Crossing
(2022)
Heavy‐atom‐containing clusters, nanocrystals, and other semiconductors can sensitize the triplet states of their surface‐bonded chromophores, but the energy loss, such as nonradiative deactivation, often prevents the synergistic light emission in their solid‐state coassemblies. Cocrystallization allows new combinations of molecules with complementary properties for achieving functionalities not available in single components. Here, the cocrystal formation that employs platinum(II) acetylacetonate (Pt(acac)\(_{2}\)) as a triplet sensitizer and electron‐deficient 1,4,5,8‐naphthalene diimides (NDIs) as organic phosphors is reported. The hybrid cocrystals exhibit room‐temperature phosphorescence confined in the low‐lying, long‐lived triplet state of NDIs with photoluminescence (PL) quantum yield (Φ\(_{PL}\)) exceeding 25% and a phosphorescence lifetime (τ\(_{Ph}\)) of 156 µs. This remarkable PL property benefits from the noncovalent electronic and spin–orbital coupling between the constituents.
A series of novel imide‐functionalized C\(_{64}\) nanographenes is investigated as acceptor components in organic solar cells (OSCs) in combination with donor polymer PM6. These electron‐poor molecules either prevail as a monomer or self‐assemble into dimers in the OSC active layer depending on the chosen imide substituents. This allows for the controlled stacking of electron‐poor and electron‐rich π–scaffolds to establish a novel class of non‐fullerene acceptor materials to tailor the bulk‐heterojunction morphology of the OSCs. The best performance is observed for derivatives that are able to self‐assemble into dimers, reaching power conversion efficiencies of up to 7.1%.
The synthesis and characterization of laterally extended azabora[5]‐, ‐[6]‐ and ‐[7]helicenes, assembled from N‐heteroaromatic and dibenzo[g,p]chrysene building blocks is described. Formally, the π‐conjugated systems of the pristine azaborole helicenes were enlarged with a phenanthrene unit leading to compounds with large Stokes shifts, significantly enhanced luminescence quantum yields (Φ) and dissymmetry factors (g\(_{lum}\)). The beneficial effect on optical properties was also observed for helical elongation. The combined contributions of lateral and helical extensions resulted in a compound showing green emission with Φ of 0.31 and |g\(_{lum}\)| of 2.2×10\(^{−3}\), highest within the series of π‐extended azaborahelicenes and superior to emission intensity and chiroptical response of its non‐extended congener. This study shows that helical and lateral extensions of π‐conjugated systems are viable strategies to improve features of azaborole helicenes. In addition, single crystal X‐ray analysis of configurationally stable [6]‐ and ‐[7]helicenes was used to provide insight into their packing arrangements.
Palladium‐catalyzed [5+2] annulation of 1‐boraphenalenes with ortho‐dihaloarenes afforded negatively curved π‐extended pleiadienes. Two benzo[1,2‐i:4,5‐i’]dipleiadienes (BDPs) featuring a seven‐six‐seven‐membered ring arrangement were synthesized and investigated. Their crystal structure revealed a unique packing arrangement and theoretical calculations were employed to shed light onto the dynamic behavior of the BDP moiety and its aromaticity. Further, a naphthalene‐fused pleiadiene was stitched together by oxidative cyclodehydrogenation to yield an additional five‐membered ring. This formal azulene moiety led to distinct changes in optical and redox properties and increased perturbation of the aromatic system.
A series of bis‐(4’‐pyridylethynyl)arenes (arene=benzene, tetrafluorobenzene, and anthracene) were synthesized and their bis‐N‐methylpyridinium compounds were investigated as a class of π‐extended methyl viologens. Their structures were determined by single crystal X‐ray diffraction, and their photophysical and electrochemical properties (cyclic voltammetry), as well as their interactions with DNA/RNA were investigated. The dications showed bathochromic shifts in emission compared to the neutral compounds. The neutral compounds showed very small Stokes shifts, which are a little larger for the dications. All of the compounds showed very short fluorescence lifetimes (<4 ns). The neutral compound with an anthracene core has a quantum yield of almost unity. With stronger acceptors, the analogous bis‐N‐methylpyridinium compound showed a larger two‐photon absorption cross‐section than its neutral precursor. All of the dicationic compounds interact with DNA/RNA; while the compounds with benzene and tetrafluorobenzene cores bind in the grooves, the one with an anthracene core intercalates as a consequence of its large, condensed aromatic linker moiety, and it aggregates within the polynucleotide when in excess over DNA/RNA. Moreover, all cationic compounds showed highly specific CD spectra upon binding to ds‐DNA/RNA, attributed to the rare case of forcing the planar, achiral molecule into a chiral rotamer, and negligible toxicity toward human cell lines at ≤10 μM concentrations. The anthracene‐analogue exhibited intracellular accumulation within lysosomes, preventing its interaction with cellular DNA/RNA. However, cytotoxicity was evident at 1 μM concentration upon exposure to light, due to singlet oxygen generation within cells. These multi‐faceted features, in combination with its two‐photon absorption properties, suggest it to be a promising lead compound for development of novel light‐activated theranostic agents.
Proton‐coupled electron‐transfer (PCET) processes play a key role in biocatalytic energy conversion and storage, for example, photosynthesis or nitrogen fixation. Here, we report a series of bipyridine‐containing di‐ to tetranuclear Ru(bda) macrocycles 2 C–4 C (bda: 2,2′‐bipyridine‐6,6′‐dicarboxylate) to promote O−O bond formation. In photocatalytic water oxidation under neutral conditions, all complexes 2 C–4 C prevail in a folded conformation that support the water nucleophilic attack (WNA) pathway with remarkable turnover frequencies of up to 15.5 s\(^{−1}\) per Ru unit respectively. Single‐crystal X‐ray analysis revealed an increased tendency for intramolecular π‐π stacking and preorganization of the proximal bases close to the active centers for the larger macrocycles. H/D kinetic isotope effect studies and electrochemical data demonstrate the key role of the proximal bipyridines as proton acceptors in lowering the activation barrier for the crucial nucleophilic attack of H\(_{2}\)O in the WNA mechanism.
Water‐soluble multinuclear complexes based on ruthenium 2,2′‐bipyridine‐6,6′‐dicarboxylate (bda) and ditopic bipyridine linker units are investigated in three‐component visible light‐driven water oxidation catalysis. Systematic studies revealed a strong enhancement of the catalytic efficiency in the absence of organic co‐solvents and with increasing oligomer length. In‐depth kinetic and morphological investigations suggest that the enhanced performance is induced by the self‐assembly of linear Ru(bda) oligomers into aggregated superstructures. The obtained turnover frequencies (up to 14.9 s\(^{−1}\)) and turnover numbers (more than 1000) per ruthenium center are the highest reported so far for Ru(bda)‐based photocatalytic water oxidation systems.
Perylene bisimides (PBIs) are among the best fluorophores but have to be enwrapped for optoelectronic applications by large and heavy substituents to prevent their ππ‐stacking, which is known to accelerate non‐radiative decay processes in the solid state. Here, light‐weight di‐tert‐butylsilyl groups are introduced to bridge 1,12‐dihydroxy and 1,6,7,12‐tetrahydroxy PBIs to afford sublimable dyes for vacuum‐processed optoelectronic devices. For both new compounds, this substitution provides a twisted and shielded perylene π‐core whose, via OSiObridges, rigid structure affords well‐resolved absorption and emission spectra with strong fluorescence in solution, as well as in the solid state. The usefulness of these dyes for vacuum‐processed optoelectronic devices is demonstrated in organic light‐emitting diodes (OLEDs) that show monomer‐like emission spectra and high maximum external quantum efficiency (EQEmax) values of up to 3.1% for the doubly silicon‐bridged PBI.