Refine
Has Fulltext
- yes (582)
Year of publication
- 2015 (582) (remove)
Document Type
- Journal article (427)
- Doctoral Thesis (146)
- Working Paper (4)
- Conference Proceeding (3)
- Other (1)
- Preprint (1)
Language
- English (582) (remove)
Keywords
- expression (19)
- ATLAS detector (18)
- proton-proton collision (13)
- cancer (11)
- in vitro (11)
- therapy (11)
- Higgs boson (10)
- endothelial cells (9)
- infection (9)
- physics (9)
- Topologischer Isolator (8)
- gene expression (8)
- inflammation (8)
- activation (7)
- antibodies (7)
- gene (7)
- management (7)
- multiple sclerosis (7)
- apoptosis (6)
- blood (6)
- cells (6)
- diagnosis (6)
- guidelines (6)
- membrane proteins (6)
- mice (6)
- mortality (6)
- resistance (6)
- Drosophila (5)
- EEG (5)
- P300 (5)
- Taufliege (5)
- behavior (5)
- biodiversity (5)
- children (5)
- depression (5)
- disease (5)
- identification (5)
- metaanalysis (5)
- rat (5)
- states (5)
- survival (5)
- Aspergillus fumigatus (4)
- Candida albicans (4)
- DNA methylation (4)
- Krebs <Medizin> (4)
- LHC (4)
- Quecksilbertellurid (4)
- West Africa (4)
- blood-brain barrier (4)
- central nervous system (4)
- climate change (4)
- complex (4)
- energy (4)
- follow-up (4)
- impact (4)
- in vivo (4)
- inhibition (4)
- macrophages (4)
- mechanisms (4)
- metabolism (4)
- model (4)
- mouse model (4)
- mouse models (4)
- multicenter (4)
- multiple myeloma (4)
- nitric oxide (4)
- organic semiconductors (4)
- oxidative stress (4)
- phosphorylation (4)
- positron emission tomography (4)
- proteins (4)
- radiotherapy (4)
- randomized controlled trial (4)
- topological insulators (4)
- virulence (4)
- ATLAS (3)
- B cells (3)
- DNA damage (3)
- ELISPOT (3)
- EMG (3)
- Elektronischer Transport (3)
- Ereigniskorreliertes Potenzial (3)
- Exziton (3)
- Femtosekundenspektroskopie (3)
- Festkörperphysik (3)
- HgTe (3)
- Ladungstransfer (3)
- Myc (3)
- RNA-Seq (3)
- Selbstorganisation (3)
- Serotonin (3)
- T cells (3)
- Ultrakurzzeitspektroskopie (3)
- Vaccinia-Virus (3)
- W boson (3)
- Z boson (3)
- active zone (3)
- acute ischemic stroke (3)
- angiogenesis (3)
- anxiety (3)
- association (3)
- attention (3)
- autoimmunity (3)
- autophagy (3)
- binding (3)
- binding analysis (3)
- biomarkers (3)
- brain (3)
- brain-computer interface (3)
- breast cancer (3)
- cell wall (3)
- charge transfer (3)
- chronic kidney disease (3)
- classification (3)
- communication (3)
- crystal structure (3)
- cytotoxicity (3)
- decay (3)
- dendritic cells (3)
- differentiation (3)
- drug (3)
- dynamics (3)
- ecosystem services (3)
- emission (3)
- epidemiology (3)
- epithelial cells (3)
- escherichia coli (3)
- evolution (3)
- experimental autoimmune encephalomyelitis (3)
- exposure (3)
- fear (3)
- fluorescence microscopy (3)
- generation (3)
- glioblastoma multiforme (3)
- growth (3)
- heart (3)
- honeybee (3)
- involvement (3)
- learning and memory (3)
- lesions (3)
- melanoma (3)
- memory (3)
- mesenchymal stem cells (3)
- mitochondria (3)
- models (3)
- mushroom body (3)
- mutations (3)
- nervous system (3)
- olfaction (3)
- outcomes (3)
- perception (3)
- performance (3)
- permeability (3)
- polymorphism (3)
- proteomics (3)
- radiosensitivity (3)
- remote sensing (3)
- reveals (3)
- risk (3)
- risk factors (3)
- safety (3)
- scale (3)
- schistosomiasis (3)
- schizophrenia (3)
- sepsis (3)
- stem-cell transplantation (3)
- synaptic plasticity (3)
- tight junctions (3)
- transcriptome (3)
- trial (3)
- water (3)
- ALS (2)
- Aggregation (2)
- Angiogenese (2)
- Angststörung (2)
- Antigen CD8 (2)
- Arzneimittel (2)
- B-lymphocytes (2)
- BCI (2)
- Bacillus subtilis (2)
- Biene (2)
- Biologische Uhr (2)
- Brain-computer interface (2)
- Burkina Faso (2)
- CD8 (2)
- CXCR4 (2)
- Charcot-Marie-Tooth (2)
- Chlamydia trachomatis (2)
- DNA repair (2)
- Data Mining (2)
- Dendritische Zelle (2)
- Drosophila melanogaster (2)
- Early Basso Continuo (2)
- Early Music (2)
- Echinococcus (2)
- Elektronentransfer (2)
- Fabry disease (2)
- Fc-receptor (2)
- Finanzmathematik (2)
- Fluoreszenz (2)
- Fotoionisation (2)
- Fuchsbandwurm (2)
- Gehirn-Computer-Schnittstelle (2)
- HIV (2)
- Inhibitor (2)
- Ionic Liquids (2)
- Kernspintomografie (2)
- Konditionierung (2)
- LASP1 (2)
- LC-MS/MS (2)
- LMHFV (2)
- Leishmaniose (2)
- Löslichkeit (2)
- Maschinelles Lernen (2)
- Maus (2)
- Melanom (2)
- Mesenchymzelle (2)
- Molekularbiologie (2)
- Molekulardynamik (2)
- Mycobacterium (2)
- Netzwerk (2)
- Optimale Kontrolle (2)
- Performance practice (2)
- Perylenbisimid (2)
- Pharmakokinetik (2)
- Pump-Probe-Technik (2)
- Pyrolyse (2)
- Rezeptor (2)
- Spintronik (2)
- Staphylococcus aureus (2)
- Supersymmetrie (2)
- Supersymmetry (2)
- Systemisches Risiko (2)
- T lymphocytes (2)
- TAVI (2)
- TGF-beta (2)
- Theoretische Chemie (2)
- Therapie (2)
- Transkription <Genetik> (2)
- Ultraschnelle Photochemie (2)
- Ultraviolett-Photoelektronenspektroskopie (2)
- Wettbewerb (2)
- Wirkstofffreisetzung (2)
- Zellkultur (2)
- absorption (2)
- adaptive immune system (2)
- adenocarcinoma (2)
- adults (2)
- aggregation (2)
- aging (2)
- anatomy (2)
- antileishmanial (2)
- avoidance learning (2)
- bees (2)
- biodiversity conservation (2)
- biofilm formation (2)
- biofilms (2)
- biomarker (2)
- bone disease (2)
- bumblebees (2)
- butterflies (2)
- cardiovascular (2)
- cardiovascular disease (2)
- cell membranes (2)
- cell proliferation (2)
- cell staining (2)
- chemokine receptor (2)
- chlamydia (2)
- chronic stress (2)
- competition (2)
- complement (2)
- conservation (2)
- convection volume (2)
- cytokinesis (2)
- cytoskeleton (2)
- deficiency (2)
- degradation (2)
- demyelination (2)
- development (2)
- diabetes mellitus (2)
- disability (2)
- domain (2)
- down regulation (2)
- drug metabolism (2)
- echocardiography (2)
- ecology (2)
- electronic structure (2)
- embodied cognition (2)
- emotion (2)
- emotional facial expressions (2)
- energy transfer (2)
- enzyme-linked immunoassays (2)
- event-related potentials (2)
- excitations (2)
- experience (2)
- facial expressions (2)
- fibrosis (2)
- fluorescence (2)
- fluorescent probes (2)
- food (2)
- food security (2)
- fracture healing (2)
- gastric cancer (2)
- gender (2)
- genetics (2)
- genome sequence (2)
- genome-wide association (2)
- glaucoma surgery (2)
- glucocorticoids (2)
- habitats (2)
- heart failure (2)
- histone H2AX (2)
- human african trypanosomiasis (2)
- human brain (2)
- immune response (2)
- immunotherapy (2)
- in vivo imaging (2)
- incidence (2)
- innate immunity (2)
- insects (2)
- insulator (2)
- insulin resistance (2)
- interband cascade lasers (2)
- interface (2)
- interval timing (2)
- intuition (2)
- invasive pulmonary aspergillosis (2)
- ion channels (2)
- ischemic stroke (2)
- kidneys (2)
- leaf-cutting ants (2)
- leishmania major (2)
- lines (2)
- lipids (2)
- localization microscopy (2)
- luminescence (2)
- lymphoma (2)
- magnetic resonance imaging (2)
- malaria (2)
- mast cells (2)
- melanoma cells (2)
- messenger RNA (2)
- microarray (2)
- microenvironment (2)
- microglomeruli (2)
- modulation (2)
- molecular dynamics (2)
- molecular imaging (2)
- monocytes (2)
- motor proteins (2)
- mycobacterium tuberculosis (2)
- myocardial infarction (2)
- near-infrared spectroscopy (2)
- nerve fibers (2)
- neuromuscular junction (2)
- neuronal differentiation (2)
- neuropathic pain (2)
- neurotransmitter release (2)
- neurotrophic factor (2)
- next generation sequencing (2)
- oestrogen receptor signalling (2)
- organische Halbleiter (2)
- pathogenicity (2)
- pathway (2)
- pathways (2)
- phasic affective modulation (2)
- plasmodium falciparum (2)
- polarization (2)
- postnatal development (2)
- pregnancy (2)
- prevalence (2)
- processing fluency (2)
- prognostic value (2)
- protein (2)
- protein kinase (2)
- protein-coupled receptors (2)
- proton-proton-collision (2)
- proton–proton collisions (2)
- psychiatric disorders (2)
- radioiodine therapy (2)
- receptor beta (2)
- receptors (2)
- recommendations (2)
- regulation (2)
- regulatory T cells (2)
- repair (2)
- replacement (2)
- reporter gene (2)
- rolipram (2)
- semantic coherence (2)
- sensory neurons (2)
- serum (2)
- sex chromosome evolution (2)
- sizing (2)
- skin (2)
- smoking (2)
- snoRNA (2)
- spin (2)
- startle (2)
- startle reflex (2)
- stroke (2)
- structure-function relationships (2)
- subthalamic nucleus (2)
- subventricular zone (2)
- super-resolution microscopy (2)
- suppressor cells (2)
- surgery (2)
- susceptibility (2)
- synthetic aperture radar (2)
- system (2)
- temperature (2)
- tissue engineering (2)
- topological insulator (2)
- transcription (2)
- transcription factors (2)
- traumatic brain injury (2)
- treatment (2)
- tumor (2)
- tumor immunity (2)
- tumor-infiltrating lymphocytes (2)
- tumors (2)
- type 2 diabetes (2)
- ultrafast photochemistry (2)
- unpleasant pictures (2)
- vacancy (2)
- vaccine (2)
- vaccinia virus (2)
- validation (2)
- variants (2)
- virotherapy (2)
- "-omics" (1)
- (+)-limonene (1)
- (bi)pyridine-based ligand (1)
- 1,25-dihydroxyvitamin D\(_{3}\) (1)
- 1550 nm (1)
- 1st International Workshop (1)
- 2-APB (1)
- 2-dimensional speckle tracking (1)
- 2-pore potassium channel (1)
- 2015 (1)
- 2B (1)
- 3 Tesla (1)
- 3-D liver model (1)
- 3-dimensional structure (1)
- 3-dimensional visualization (1)
- 3D printing (1)
- 3D topological insulator (1)
- 4'-hydroxylation (1)
- 4D (1)
- 4H (1)
- 5-HTT (1)
- 53BP1 (1)
- A(2B) receptors (1)
- A-priori-Wissen (1)
- AAC (1)
- ABA receptors (1)
- ACP5 (1)
- AIDS (1)
- ANOVA (1)
- ARPES (1)
- AS clavicle plate (1)
- ASAR (1)
- ASAXS (1)
- ATLAS <Teilchendetektor> (1)
- ATLAS-Detektor (1)
- AZD6244 (1)
- Abschattung (1)
- Acromesomelic dysplasias (1)
- Acromyrmex ambiguus (1)
- Active pharmaceutical ingredients (1)
- Acyrthosiphon pisum (1)
- Adaptives Immunsystem (1)
- Adenosin (1)
- Adenosine receptors (1)
- Adenosinrezeptor (1)
- Adhäsion (1)
- Adipogenesis (1)
- Advanced Driver Assistance Systems (1)
- Africa (1)
- Afrika (1)
- Aggregat <Chemie> (1)
- Agrarproduktion (1)
- Akt (1)
- Alpha Neurofeedback (1)
- Alzheimer disease (1)
- Alzheimer`s disease (1)
- Alzheimerkrankheit (1)
- Aminosäuren (1)
- Amphibia (1)
- Amphiphile Verbindungen (1)
- Amyotrophe Lateralsklerose (1)
- Analyse (1)
- Analytik (1)
- Angeregter Zustand (1)
- Angiogenesis (1)
- Angst (1)
- Animal studies (1)
- Annäherung-Vermeidung (1)
- Anpassungstest (1)
- Anreizsystem (1)
- Antikörper (1)
- Anura (1)
- Anxiety Disorders (1)
- Apallisches Syndrom (1)
- Apoptose (1)
- Apoptosis (1)
- Application-Aware Resource Management (1)
- Approach-Avoidance (1)
- Arachidonsäure (1)
- Arbeitsteilung (1)
- Arctic (1)
- Artefakt <Bildgebende Diagnostik> (1)
- Arthroleptis amphibia (1)
- Arthrose (1)
- Arthrosis deformans (1)
- Arzneimitteldesign (1)
- Arzneimittelforschung (1)
- Arzneimittelmarkt (1)
- Assoziatives Gedächtnis (1)
- Astrozyten (1)
- Au/Ge(111) (1)
- Audit sampling (1)
- Aufmerksamkeit (1)
- Ausbreitung (1)
- Australian stingless bees (1)
- Aversive Konditionierung (1)
- Axonal degeneration (1)
- Aδ- and C-fibers (1)
- B-Lymphocyten (1)
- B-Lymphozyt (1)
- B-MYB (1)
- B-cell lymphoma (1)
- B7-H1 (1)
- BH3 domains (1)
- BMPR1B (1)
- BNIP3 (1)
- BRAF(V600E) mutation (1)
- BRICS-Staaten (1)
- BSM Higgs boson (1)
- BV-2 (1)
- BaPb\(_{1-X}\)Bi\(_{X}\)O\(_{3}\) (1)
- Bacillus-Calmette-Guerin (1)
- Bakterielle Infektion (1)
- Banks Islands (1)
- Bariatric surgery (1)
- Bauchspeicheldrüsenkrebs (1)
- Bcl-2 proteins (1)
- Benin (1)
- Benutzerfreundlichkeit (1)
- Benutzerfreundlichkeit/ Benutzbarkeit (1)
- Beschriftung (1)
- Beschriftung von Straßen (1)
- Bessle functions (1)
- Bewusstsein (1)
- Bewusstseinsstörung (1)
- Bewusstseinsstörungen (1)
- Beyond Standard Model (1)
- Bienen <Familie> (1)
- Biholomorphe Abbildung (1)
- Binomialverteilung (1)
- BioID (1)
- Biochemie (1)
- Biological Networks (1)
- Biologie / Zellbiologie (1)
- Biologischer Abbau (1)
- Bioverfügbarkeit (1)
- Blockcopolymere (1)
- Bola-Amphiphil (1)
- Bone marrow stromal cell (BMSC) (1)
- Bose-Einstein Correlations (1)
- Bovis (1)
- Brain-Computer Interface (BCI) (1)
- BrdU replication banding pattern (1)
- BrdU/dT replication banding (1)
- Bruchpilot (1)
- Bunnell (1)
- Burkitt (1)
- C virus (1)
- C-11-methionine pet (1)
- C-6-H (1)
- C-Myc (1)
- C. elegans (1)
- CB1 receptor antagonists (1)
- CD1c⁺ mDC (1)
- CD1d (1)
- CD39 (1)
- CD4 (1)
- CD4 T cells (1)
- CD4+T cells (1)
- CD73 (1)
- CD8 T cell (1)
- CD8 T-Zelle (1)
- CD8+T cells (1)
- CGG repeat (1)
- CNS disease (1)
- CNS injury (1)
- CO-releasing molecules (1)
- CP-690,550 (1)
- CPG Island (1)
- CT (1)
- CTL function (1)
- CTSE (1)
- CXCR4/SDF-1 (1)
- CYP induction (1)
- CYP inhibition (1)
- CaMKII (1)
- Ca\(^{2+}\) channels (1)
- Caenorhabditis elegans (1)
- Carbon Nanotube (1)
- Carrefour (1)
- CePt5 (1)
- Cellular Networks (1)
- Cestoda Taeniidae (1)
- ChAT (1)
- ChIP-sequencing (1)
- ChT1 (1)
- Charcot-Marie-Syndrom (1)
- Chemische Reinheit (1)
- Chemotherapie (1)
- China (1)
- China Resource (1)
- Chiral-sensitive Specktroskopie (1)
- Chiralität <Chemie> (1)
- Chirurgie (1)
- Chlamydia (1)
- Circadian Rhythms (1)
- Circadian clock (1)
- Clec16a (1)
- Co-option (1)
- Comparative politics (1)
- Complex Systems (1)
- Compound eyes (1)
- Computational Investigation (1)
- Computational chemistry (1)
- Computational drug-design (1)
- Computerkartografie (1)
- Congo Basin (1)
- Contemporary Philosophy (1)
- Continuous Sample Path (1)
- Controllability (1)
- Controlled release (1)
- Copula (1)
- Copula <Mathematik> (1)
- Cortex (1)
- Costa Rica (1)
- Coulomb interaction (1)
- Counterparty Risk (1)
- CpG island hypermethylation (1)
- Crab-Nebel (1)
- Credibility interval (1)
- Crohn’s disease (1)
- Crossed Andreev Refexion (1)
- Crossed Andreev Reflection (1)
- Cryptochrom (1)
- Cu(111) (1)
- CuPc (1)
- Cultural studies (1)
- Cuscuta (1)
- Cutaneous leishmaniasis (1)
- Cyclo-AMP (1)
- Cynoglossus semilaevis (1)
- Cys-loop receptor (1)
- Cystein (1)
- Cytotoxizität (1)
- Côte d’Ivoire (1)
- D-Norm (1)
- D2 receptors (1)
- DMRT1 (1)
- DNA (1)
- DNA Mismatch repair (1)
- DNA barcoding (1)
- DNA double strand breaks (1)
- DNA double-strand break (1)
- DNA helicase (1)
- DNA repair defect (1)
- DNA-binding proteins (1)
- DNS-Reparatur (1)
- DREAM (1)
- Darmflora (1)
- Data Modeling (1)
- Datenmodell (1)
- Defective Democracy (1)
- Delphi procedure (1)
- Democracy Measurement (1)
- Democratic People's Republic of Korea (1)
- Demokratie (1)
- Demyelinisierung (1)
- Demökologie (1)
- Depression (1)
- Design and Development (1)
- Detektor (1)
- Diabetes mellitus (1)
- Diabetic polyneuropathy (1)
- Dickdarmkrebs (1)
- Differentialgleichung (1)
- Differentiation (1)
- Diffusion (1)
- Digital Elevation Model (1)
- Digital Humanities (1)
- Digitale Karte (1)
- Dimension 3 (1)
- Dimensional Crossover (1)
- Dirichlet-Reihe (1)
- Dissoziative Photoionisation (1)
- Diversifikation <Biologie> (1)
- Diversity (1)
- Division of labor (1)
- Dixon (1)
- Doctorial Consortium, WI 2015 (1)
- Donor-Photosensibilisator-Akzeptor Triade (1)
- Double Negative B cells (1)
- Drahtloses lokales Netz (1)
- Dreieck (1)
- Driver assistance (1)
- Driving simulation (1)
- Drug design (1)
- Dual 3'seq (1)
- Duodenal Jejunal Bypass (1)
- Dynamic Causal Modeling (1)
- Dünne Schicht (1)
- Dünnschichtsolarzelle (1)
- EAE (1)
- EDX spectra (1)
- EEG data (1)
- EEG/ERP (1)
- ENVISAT ASAR WSM (1)
- EPC (1)
- ERK map kinease (1)
- ERPs (Event-Related Potentials) (1)
- ESC (1)
- EU (1)
- EVER1 (1)
- EVER2 (1)
- EZH2 differentiation trichostatin (1)
- Eierstockkrebs (1)
- Eierstocktumor (1)
- Einzelhandel (1)
- Electrochemical energy storage (1)
- Electrospinning (1)
- Elektroencephalographie (1)
- Elektronencephalographie (1)
- Elektronendichte (1)
- Elektronenkorrelation (1)
- Elektronenstruktur (1)
- Elektronische Eigenschaften (1)
- Elektrophysiologie (1)
- Elliptische Differentialgleichung (1)
- Elongation (Transkription) (1)
- Emerging Power (1)
- Emery Kivelson line (1)
- Encapsulation (1)
- Endothel (1)
- Energiespeicher (1)
- Energietransfer (1)
- Energietransfer <Mikrophysik> (1)
- Enoyl-acyl-carrier-protein-Reductase <Enoyl-[acyl-carrier-protein]-Reductase> (1)
- Enrique Gaspar y Rimbau (1)
- Entzündung (1)
- Envisat (1)
- Enzyme-Linked Immunospot assay (ELISPOT) (1)
- EphA2 (1)
- Ephrin ligand (1)
- Ephrine (1)
- Epigenetic (1)
- Epigenetik (1)
- Escherichia coli (1)
- Escherichia coli AlkA (1)
- Ethiopia (1)
- European Society (1)
- European experts (1)
- Europäische Kommission / Generaldirektion Wettbewerb (1)
- Evaluation (1)
- Evans syndrome (1)
- Evaporation-Induced Self-Assembly (1)
- Exact-controllability (1)
- Exciton (1)
- Experimental physics (1)
- Expert System (1)
- Expertensystem (1)
- Exponential smoothing (1)
- Exponential smoothing with covariates (1)
- Extrakt (1)
- Extreme Value Theory (1)
- Extremwertstatistik (1)
- Extremwerttheorie (1)
- Eyjafjallajökull 2010 (1)
- FANCA (1)
- FANCD2 (1)
- FDG (1)
- FDG PET/CT (1)
- FDG-PET/CT (1)
- FDG-PET/MRI (1)
- FISH (1)
- FMMs (1)
- FMR1 (1)
- FMR2 (1)
- FOXM1 (1)
- FTIR spectroscopy (1)
- FTY720-P (1)
- FXR1 (1)
- FXR2 (1)
- FabI (1)
- Fabry-associated pain (1)
- Fahrerassistenzsystem (1)
- Family Investigation of Nephropathy and Diabetes (1)
- Fanconi anemia (1)
- Farbstoff (1)
- Fc-Rezeptor (1)
- Fear (1)
- Fear Conditioning (1)
- Fear Extinction (1)
- Femtochemie (1)
- Femtochemistry (1)
- Femtosecond Spectroscopy (1)
- Femtosekunden Pulsformung (1)
- Femtosekundenbereich (1)
- Femtosekundenlaser (1)
- Fettsucht (1)
- Fettzelle (1)
- Fibroblastenwachstumsfaktor (1)
- Financial Networks (1)
- Finanzielle Netzwerke (1)
- Finite-Elemente-Methode (1)
- Firmwert (1)
- Flotillin (1)
- Flugkörper (1)
- Fluoreszenz-Resonanz-Energie-Transfer (1)
- Fluoreszenzmikroskopie (1)
- Fokker-Planck optimality systems (1)
- Fokker-Planck-Gleichung (1)
- Force Field (1)
- Formation Flight (1)
- Formmessung (1)
- Fotochemie (1)
- Foxp3 (1)
- Fragmentierung (1)
- Französische Feldwespe (1)
- Free Energy Perturbation (1987 : Princeton, NJ) (1)
- Freedom House (1)
- Funktionelle Kernspintomografie (1)
- Furcht (1)
- Future Internet (1)
- G-Protein gekoppelte Rezeptoren (1)
- G-quadruplex motifs (1)
- GABA(A) receptor (1)
- GABA-Rezeptor (1)
- GAS2L3 (1)
- GBM (1)
- GDF-15 (1)
- GIS (1)
- GRO alpha (1)
- GSTP1 (1)
- GaAs (1)
- Gallium (1)
- Galliumarsenid (1)
- Gamma-Konvergenz (1)
- Gammaastronomie (1)
- Gammastrahlenastronomie (1)
- Gefahrenlernen (1)
- Gehirn-Computer Schnittstelle (1)
- Gelernte Hilflosigkeit (1)
- Generalized Pareto Distribution (1)
- Genetic engineering (1)
- Genexpression (1)
- German Stroke Registers Study Group (1)
- Geschützte Natur (1)
- Gewebe (1)
- Gitterbaufehler (1)
- Gleichberechtigung (1)
- Glioblastom (1)
- Glucosetransportproteine (1)
- Goodness-of-Fit Test (1)
- Governance (1)
- Graphene (1)
- Graphentheorie (1)
- Grebe dysplasia (1)
- Grenzfläche (1)
- Growth (1)
- Growth-differentiation Factor 15 (1)
- Guinean rain forest (1)
- HCMV infection (1)
- HCV genotype 2 (1)
- HE-3 diffusion MRI (1)
- HEK cells (1)
- HHblits (1)
- HIF-1α (1)
- HIV-1-infected subjects (1)
- HIV-infected patients (1)
- HLA-G (1)
- HLA-G gene (1)
- Habitat (1)
- Halbleitergrenzflächen (1)
- Halbleiterphysik (1)
- Halobacterium halobium (1)
- Handelsformat (1)
- Handelsforschung (1)
- HeLa cells (1)
- Hepatitis B virus reactivation (1)
- Heubacillus (1)
- HeuristicsMiner algorithm (1)
- Heuschrecken <Überfamilie> (1)
- Hexaarylbenzole (1)
- Hg1-xCdxTe (1)
- Higgs-Teilchen (1)
- Hilfsmittel (1)
- Hippocampus (1)
- Hirschsprung disease (1)
- Hochmagnetfeld (1)
- Hodgkin-lymphoma (1)
- Homoptera aphididae (1)
- Honeybee (1)
- Honigbiene (1)
- Host cell death (1)
- Hubbard-Modell (1)
- Human Factors (1)
- Human Host (1)
- Human papillomavirus (1)
- Hymenoptera (1)
- Hypoxie (1)
- I-tasser (1)
- ICT (1)
- IFN-γ (1)
- III adenylyl cyclases (1)
- III secretion (1)
- III secretion system (1)
- IL-12B (1)
- IL-12p40 (1)
- IL-15 (1)
- IL-17 (1)
- IL-2 (1)
- IL-4 (1)
- IL-5 (1)
- IL-6 Inhibition (1)
- IL12B (1)
- IMA2.1 (1)
- ISPMF (1)
- ITS2 (1)
- Ileal Trasposition (1)
- Illusorische Korrelation (1)
- Immune (1)
- Immunologie (1)
- Immunology (1)
- Immunsuppression (1)
- Immunsystem (1)
- Impfplan (1)
- Impfung (1)
- Implantat (1)
- Impulsformung (1)
- In vitro (1)
- Indian Economy (1)
- Indien / Government (1)
- Indien / Parliament / House of the People (1)
- Information Extraction (1)
- Information Retrieval (1)
- InhA (1)
- Inhibition (1)
- Innovation (1)
- Instrument Control Toolbox (1)
- Insulin-like Growth Factor I (1)
- Insulinresistenz (1)
- Interaction analysis (1)
- Interaktive Karten (1)
- Interleukin 4 (1)
- Interleukin 6 (1)
- Internationale Politik (1)
- Internationaler Wettbewerb (1)
- Intracellular replication (1)
- Iridiumkomplexe (1)
- J-aggregate behavior (1)
- Johnstons organ (1)
- K+ channel (1)
- K-PG radiation (1)
- K279a (1)
- K2P channels (1)
- KCNK5 (1)
- KDIGO (1)
- K\(_{2P}\)5.1 (1)
- Kapitalverflechtung (1)
- Kapitalverflechtungen (1)
- Kerinokeratosis papulosa (1)
- Kiefernrindenextrakt (1)
- Killerzelle (1)
- Klassifikation (1)
- Klimawandel (1)
- Klimaänderung (1)
- Knieschmerzen (1)
- Knochenregeneration (1)
- Knockout <Molekulargenetik> (1)
- Knowledge-based Systems Engineering (1)
- Kohlenmonoxid (1)
- Kohlenstoff-Nanoröhre (1)
- Kohlenwasserstoffe (1)
- Kolonialismus (1)
- Kommunikationshilfe (1)
- Komplement (1)
- Komplexes System (1)
- Kondo cloud (1)
- Kondo effect (1)
- Kondo-Effekt (1)
- Konfidenzintervall (1)
- Konforme Abbildungen (1)
- Konkurrenzanalyse (1)
- Konstruktionsmethoden (1)
- Kontrakttheorie (1)
- Kontrollierte Wirkstofffreisetzung (1)
- Kontrolltheorie (1)
- Kooperativität (1)
- Korrelation (1)
- Korruption (1)
- Korruption von Mitarbeitern (1)
- Kraftfeld (1)
- Kristall (1)
- Kristalloberfläche (1)
- L-DOPA (1)
- LCP (1)
- LEED (1)
- LINC complex (1)
- LINE-1 retrotransposition (1)
- LIS (1)
- LPP (1)
- LTR retrotransposons (1)
- LULCC (1)
- Land Cover Classification (1)
- Land Surface Temperature (LST) (1)
- Landau level (1)
- Landschaftsökologie (1)
- Landwirtschaft (1)
- Large Hadron Collider (1)
- Laufkäfer (1)
- Lebensmitteleinzelhandel (1)
- Lebensqualität (1)
- Leberepithelzelle (1)
- Legionella (1)
- Leistungsbewertung (1)
- Lepton-Flavour-Verletzung (1)
- Lernen (1)
- Licht (1)
- Lieferantenwahl (1)
- Ligand (1)
- Lipid Rafts (1)
- Listeria monocytogenes (1)
- Ljapunov-Funktion (1)
- Ljapunov-Stabilitätstheorie (1)
- Ln-MOFs (1)
- Loewner theory (1)
- Loewner-Theorie (1)
- Logging (1)
- Lokalanästhesie (1)
- Lycopersicon esculentum (1)
- Lymphom (1)
- M1/M2 macrophages (1)
- MACE (1)
- MAPK signaling (1)
- MARC effect (1)
- MBE (1)
- MCPH1 (1)
- MIC ligands (1)
- MITF (1)
- MODIS image (1)
- MORN-repeat (1)
- MRI (1)
- MRSA (1)
- MSC (1)
- MSSS (1)
- MTOR (1)
- MYCN (1)
- Machine Learning (1)
- Mackenzie-River-Delta (1)
- Magerrasen (1)
- Magnetic resonance (1)
- Magnetischer Röntgenzirkulardichroismus (1)
- Majorana fermions (1)
- Makrophage (1)
- Makrophagen (1)
- Mangan (1)
- Markov-Ketten-Monte-Carlo-Verfahren (1)
- Marktstruktur (1)
- Masern (1)
- Matrix Effekte (1)
- Matrix of Democracy (1)
- Maxwell demon (1)
- Mehragentensystem (1)
- Mekong-Delta (1)
- Melanin (1)
- Melanin release (1)
- Melanomzellen (1)
- Memory B cells (1)
- Mercury Telluride (1)
- Merocyanine (1)
- Merocyanine dye (1)
- Mesenchymale Stammzelle (1)
- Messenger-RNP (1)
- Messenger-RNS (1)
- Metabolismus (1)
- Metagenom (1)
- Metallcarbonyle (1)
- Metallimplantat (1)
- Metastase (1)
- Metro (1)
- Microscopy (1)
- Mikroglia (1)
- Mismatch (1)
- Miz1 (1)
- Mobile Telekommunikation (1)
- Molecular Phenomena (1)
- Molecular Simulation (1)
- Molecular dynamics (1)
- Molecular mechanics (1)
- Molekulare Phänomene (1)
- Molekularstrahlepitaxie (1)
- Moleküldynamik (1)
- Monitoring (1)
- Monoklonaler Antikörper (1)
- Monte Carlo Simulation (1)
- Monte-Carlo Methods (1)
- Monte-Carlo-Simulation (1)
- Moonlight (1)
- Motor nerve biopsy (1)
- Multi-agent systems (1)
- Multiple sclerosis (1)
- Mumps (1)
- Muskelin (1)
- Myatrophische Lateralsklerose (1)
- Myc Transcription (1)
- Mycobacterium avium (1)
- Mycobacterium tuberculosis (1)
- Myokarditis (1)
- N400 (1)
- NADPH oxidase inhibitors (1)
- NAFLD (1)
- NEXAFS spectroscopy (1)
- NF-\(\kappa\)B (1)
- NF-κB (1)
- NFAT (1)
- NFATc1 (1)
- NFκB-activation (1)
- NGS (1)
- NKG2D (1)
- NKG2D ligands (1)
- NMDA receptor subunits NR2A and NR2B (1)
- NMR relaxation (1)
- NMR-Spektroskopie (1)
- NOD (1)
- NSN-Grenzfächen (1)
- NSN-junctions (1)
- NVP-BEZ235 (1)
- Nampt (1)
- Nanolithografie (1)
- Nanomedicine (1)
- Nanomedizin (1)
- Nanoparticles (1)
- Narendra Modi (1)
- Native Chemical Ligation (1)
- Naturstoff (1)
- Nestbau (1)
- Networks (1)
- Netzwerkmanagement (1)
- Netzwerkverwaltung (1)
- Neue Physik (1)
- Neurofeedback (1)
- Neuronal plasticity (1)
- Neuronale Plastizität (1)
- Neuropathy (1)
- Neurotrophic factors (1)
- New physics (1)
- Nichtglatte Optimierung (1)
- Nichtlineare Funktionalgleichung (1)
- Niederdimensionales System (1)
- Nisthilfe (1)
- Nonequilibrium (1)
- Nonparametric Inference (1)
- Nonsmooth optimization (1)
- Normal Distribution (1)
- Nozizeptor (1)
- Numerical Asset Valuation (1)
- Nutzen (1)
- Nutzenvergleich (1)
- OAT1 (1)
- OAT3 (1)
- OK cells (1)
- OSC (1)
- Oberfläche (1)
- Olig2 (1)
- Oligomerisation (1)
- Oligomerization (1)
- Onboard (1)
- Oncolytic Vaccinia Virus Therapy (1)
- Onkolyse (1)
- Onkolytische Vaccinia Virustherapie (1)
- Opioide (1)
- Optical spectroscopy (1)
- Optimal control problem (1)
- Optimierung (1)
- Optimization (1)
- Optische Spektroskopie (1)
- Order Statistics (1)
- Organisation (1)
- Organisationskultur (1)
- Organisationspsychologie (1)
- Organische Sulfide (1)
- Originators (1)
- Orobanche crenata (1)
- Osnabrück (1)
- Osteoarthritis (1)
- Osteogenesis (1)
- Osteoporose (1)
- Ovarian (1)
- P-glycoprotein (1)
- P-glycoprotein expression (1)
- P. falciparum (1)
- PBEF (1)
- PC-1 blockade (1)
- PCR (1)
- PD-1 (1)
- PD-L1 (1)
- PDE4-inhibitor roflumilast (1)
- PET (1)
- PFS25 (1)
- PGAS (1)
- PHMB (1)
- PI3K (1)
- POEM (1)
- Pareto-Verteilung (1)
- Parkinson's disease (1)
- Participation (1)
- Period (1)
- Permeabilität (1)
- Peroxiredoxin (1)
- Peroxiredoxin 6 (1)
- Perylenbisdicarboximide <Perylen-3,4:9,10-bis(dicarboximide)> (1)
- Perylenderivate (1)
- Petropedetidae (1)
- PfAMA1 (1)
- PfCCp protein (1)
- Pfs230 (1)
- Phagosom (1)
- Phagosomal escape (1)
- Phagozytose (1)
- Pharmaceutical markets (1)
- Pharmazeutische Industrie (1)
- Pharmazie (1)
- Phenomenology (1)
- Pheromon (1)
- Pheromon Kommunikation (1)
- Pheromon communication (1)
- Philosophy of Cognitive Science (1)
- Philosophy of Mind (1)
- Photoanregung (1)
- Photoelektron-Photoion-Koinzidenz (1)
- Photoelektronen-Photoionen-Koinzidenz (1)
- Photoelektronenspektroskopie (1)
- Photoluminescence (1)
- Photolumineszenzspektroskopie (1)
- Photosensibilisator (1)
- Phrynobatrachus amphibia (1)
- Physik jenseits des Standardmodells (1)
- Plasmamembran (1)
- Pol II (1)
- PolSAR (1)
- Polarimetrie (1)
- Polarisationspulsformung (1)
- Polistes (1)
- Political Freedom (1)
- Political Science (1)
- Political system (1)
- Politische Gleichheit (1)
- Politisches System (1)
- Polo-like kinase 1 (1)
- Polyamin (1)
- Polyethylenglykole (1)
- Polyglycidol (1)
- Polymer (1)
- Polymere (1)
- Polymilchsäure (1)
- Poorly water soluble drugs (1)
- Populationsgenetik (1)
- Prediction interval (1)
- Prefrontalt Cortex (1)
- Preisvergleich (1)
- Probenaufarbeitung (1)
- Processing Fluency (1)
- Produktinnovation (1)
- Prognose (1)
- Prostaglandin E2 (1)
- Proteaseinhibitor (1)
- Proteasomaler Abbau (1)
- Protected Area (1)
- Protein Expression (1)
- Protein crystal (1)
- Protein-Protein-Wechselwirkung (1)
- Proteine (1)
- Proton-Proton-Streuung (1)
- Präferenz (1)
- Präfrontaler Cortex (1)
- Pränatale Entwicklung (1)
- Pseudomonas aeruginosa (1)
- Psychologie (1)
- Pulmonale Applikation (1)
- Pulmonary delivery (1)
- Pulsar (1)
- Punktbeschriftungen (1)
- Pycnogenol (1)
- QW interface profile (1)
- Quadrocopter (1)
- Quality of Democracy (1)
- Qualität (1)
- Quanten-Hall-Effekt (1)
- Quantenchemie (1)
- Quanteninformation (1)
- Quantum control (1)
- RESTORE protocol (1)
- RIXS (1)
- RNA (1)
- RNA binding proteins (1)
- RNA polymerase II (1)
- RNA-seq (1)
- RNAi (1)
- RNS-Interferenz (1)
- RNS-Polymerase II (1)
- RQQ domain (1)
- RS1 Peptides (1)
- RS1 derived peptides (1)
- RSK (1)
- RT-PCR (1)
- RT-qPCT (1)
- RTS,S/AS01 malaria vaccine (1)
- Radarfernerkundung (1)
- Radioastronomie (1)
- Radiofrequenzstrahlung (1)
- Ranidae (1)
- Rapsanbau (1)
- Rashba Spin-Orbit Coupling (1)
- Rashba impurity (1)
- Rashba-Effekt (1)
- Ratte (1)
- Raumfahrzeug (1)
- Reaktionsmechanismus (1)
- Reference pricing schemes (1)
- Reflexa Roxb (1)
- Regulation (1)
- Regulatorischer T-Lymphozyt (1)
- Relevant market (1)
- Relief <Geografie> (1)
- Religion (1)
- Repression (1)
- Retail (1)
- Rheumatoid arthritis (1)
- Rhizom (1)
- Rho-GTPases (1)
- Rhodopsin (1)
- Ribosome (1)
- Riemann Hypothesis (1)
- Riemannsche Zetafunktion (1)
- Risikomanagement (1)
- Risk-sharing schemes (1)
- Routing (1)
- Ru(0001) (1)
- Ruthenium (1)
- Röntgenabsorptionsspektroskopie (1)
- Röntgenemission (1)
- Röntgenspektroskopie (1)
- Röteln (1)
- S-layer protein (1)
- S. aureus (1)
- S6KII RSK (1)
- SAPT (1)
- SAR (1)
- SAR imagery (1)
- SEQ (1)
- SLAM (1)
- SNARC (1)
- SNARC effect (1)
- SOX9 (1)
- SPECT (1)
- SQUID (1)
- SUN domain proteins (1)
- Saccharomyces cerevisiae (1)
- Saccharomyces cerevisiae telomeres (1)
- Salmonella (1)
- Salmonella enterica Typhimurium strain SL1344 (1)
- Salmonella-containing vacuole (SCV) (1)
- Salmonella/microsome assay (1)
- Salz (1)
- Salzlösung (1)
- Scheimpflug (1)
- Schistosoma mansoni (1)
- Schwere-Fermionen-System (1)
- Seide (1)
- Seiden-Fibroin (1)
- Sekundärwald (1)
- Shaggy (1)
- Shanghai (1)
- Siliciumcarbid (1)
- Silicon carbide (1)
- Silicon vacancy (1)
- Silk Fibroin (1)
- Silk-Fibroin (1)
- Simkania (1)
- Simkania negevensis (1)
- Simulation (1)
- Simvastatin (1)
- Software (1)
- Solarzellen (1)
- South Korea (1)
- Southeast China (1)
- Soziales Netzwerk (1)
- Sozialpsychologie (1)
- Spacecrafts (1)
- Spam Detection (1)
- Spermin (1)
- Sphingosine 1-Phosphate (1)
- Spin defect (1)
- Spin flip (1)
- Spin systems (1)
- Spinchemie (1)
- Spinsystem (1)
- Spray drying (1)
- Sprungmodell (1)
- Sprühtrocknung (1)
- Squalius alburnoides (1)
- Sr\(_2\)RuO\(_4\) (1)
- Stammzelle (1)
- Standardmodell <Elementarteilchenphysik> (1)
- Starry Sky (1)
- Statistics (1)
- Statistische Mechanik (1)
- Statistische Physik (1)
- Stenotrophomonas maltophilia (1)
- Step Ru surface (1)
- Stilles Lesen (1)
- Stochastic Process (1)
- Stochastischer Prozess (1)
- Streptomyces (1)
- Stress (1)
- Structrual Model (1)
- Strukturanalyse (1)
- Sub-saharan Africa (1)
- Subjektive Theorie (1)
- Substruktur (1)
- Suicidal behavior (1)
- SuperSAGE (1)
- Supercapacitor (1)
- Superkondensator (1)
- Supersaturation (1)
- Supraleiter (1)
- Supraleitung (1)
- Supramolekulare Chemie (1)
- Surface Urban Heat Island (SUHI) (1)
- Synapse (1)
- Synapses (1)
- Synchrotronstrahlung (1)
- Synthetic Aperture Radar (1)
- Systemic Risk (1)
- Szilárd (1)
- Säkularismus (1)
- T Zelle (1)
- T cell activation (1)
- T cell assay (1)
- T-Lymphozyt (1)
- T-cadherin (1)
- T-cells (1)
- TASK2 (1)
- TEN (1)
- TH1-induced senescence (1)
- TH17 cells (1)
- TI (1)
- TKTL1 (1)
- TLR7 (1)
- TLR8 (1)
- Tagesrhythmus (1)
- Tagging (1)
- Tagung (1)
- Tanzania (1)
- TbMORN1 (1)
- Technetium Tc 99m Sestamibi Rats (1)
- TerraSAR-X (1)
- Th17 (1)
- Therapeutical application (1)
- Thermoelektrizität (1)
- Thermoregulation (1)
- Thiol-Ene-Click-Chemie (1)
- Tieftemperatur (1)
- Timeless (1)
- Toll-like-Rezeptoren (1)
- Topografie (1)
- Topological Insulator (1)
- Topological edge states (1)
- Topological insulator (1)
- Topologische Randkanäle (1)
- Toulouse point (1)
- Toxizitätstest (1)
- Traffic Lights (1)
- Traffic psychology (1)
- Transcranial Magnetic Stimulation (1)
- Transcription (1)
- Transcription regulation (1)
- Transient Absorption Spectroscopy (1)
- Transiente Absorptionsspektroskopie (1)
- Transkriptionsfaktor (1)
- Transwell® system (1)
- Triad (1)
- Trypanosoma brucei (1)
- Tryptophan hydroxylase-2 (Tph2) (1)
- Tuberkelbakterium (1)
- Tumorerkrankungen (1)
- Twilight (1)
- Typ 2 (1)
- Type 1 Diabetes (1)
- UAV (1)
- UI and Interaction Design (1)
- Ubiquitinierung (1)
- Uganda (1)
- Ultimatum Game (1)
- Ultrakurzer Lichtimpuls (1)
- Unified Monitoring (1)
- United States (1)
- Unmanned Aerial Vehicle (1)
- Unternehmen (1)
- Unternehmensbewertung (1)
- Unternehmenskooperation (1)
- Upper Guinea (1)
- Urodela (1)
- Usability (1)
- User Participation (1)
- V-antigen (1)
- V. wallichii (1)
- VACV (1)
- VAChT (1)
- VCAM-1 (1)
- VIBE (1)
- Vacuum stability (1)
- Valeriana wallichii (1)
- Vascular endothelial Growth Factor (1)
- Vektorboson (1)
- Vektorfeldformer (1)
- Vektorfeldkontrolle (1)
- Verarbeitungsflüssigkeit (1)
- Verbindungen (1)
- Verdunstung (1)
- Vergleichende politische Wissenschaft (1)
- Verkapselung (1)
- Verkehrsteilnehmer (1)
- Vertikalvereinbarungen (1)
- Verunreinigung (1)
- Verzerrte Kognition (1)
- Verzerrung (1)
- Vietnam (1)
- Visualisierung (1)
- Vorläuferzelle (1)
- W Arly Pendjari WAP (1)
- WB-DW-MRI (1)
- WD40 (1)
- WH2 domain (1)
- WNT5A (1)
- WSM (1)
- Wahrnehmung (1)
- Waxy papulosis of childhood (1)
- Web2.0 (1)
- Wechselwirkung (1)
- Wert (1)
- Wespen (1)
- Westafrika (1)
- Wettbewerbsstrategie (1)
- Wilms tumour (1)
- Wireless Mesh Networks (1)
- Wirtschaftsinformatik (1)
- Wirtszelle (1)
- Wissensbasiertes System (1)
- Wnt (1)
- Wnt signalling (1)
- Wnt-signalling (1)
- Word-preferences (1)
- Wort (1)
- Wort-Präferenzen (1)
- X. laevis-type karyotype (1)
- X. tropicalis-type karyotype (1)
- Xenopus (1)
- Xenopus laevis (1)
- Xenopus tropicalis (1)
- Xiphophorus (1)
- Y chromosome (1)
- Y-gastric bypass (1)
- Yersinia enterocolitica (1)
- Yukawa coupling (1)
- Zeitgeber (1)
- Zellteilung (1)
- Zelltod (1)
- Zellzyklus (1)
- Zero-inflation (1)
- Zeta-function (1)
- Zirkulardichroismus Spektroskopie (1)
- Zonula Occludens-1 (1)
- \(\alpha\)-latrotoxin (1)
- \(\alpha\)-phase (1)
- \(\beta\)-phase (1)
- \(\gamma\)h2ax (1)
- \(^{11}\)C-Methionine-PET (1)
- \(^{18}\)F-FDG PET/CT (1)
- abnormalities (1)
- abundance (1)
- accelerator based radiosurgery (1)
- acceptance (1)
- accuracy motivation (1)
- achalasia (1)
- achilles (1)
- acoustic startle (1)
- acoustic surface plasmon (1)
- acromyrmex ambiguus (1)
- actin nucleation (1)
- actinobacteria (1)
- action potentials (1)
- active antiretroviral therapy (1)
- acts downstream (1)
- acute MK-801 (1)
- acute kidney injury (1)
- acute leukemia (1)
- acute liver failure (1)
- acute lung injury (1)
- acute management of stroke (1)
- acute myeloid leukemia (1)
- acute neurology (1)
- acute stroke (1)
- acute stroke imaging (1)
- acute stroke management (1)
- acute stroke outcome (1)
- adaptations (1)
- adaptive growth (1)
- additive manufacturing (1)
- adenosine kinase (1)
- adherence (1)
- adipocytes (1)
- adipocytokines (1)
- adrenocortical (1)
- adult neurogenesis (1)
- advertising effects (1)
- aerobic performance (1)
- aerobic power (1)
- affect (1)
- affect misattribution procedure (1)
- affective S-R compatibility (1)
- affective consequences (1)
- age (1)
- agent-based model (1)
- aggression (1)
- aging-related disease (1)
- agreement (1)
- agricultural intensification (1)
- agricultural irrigation (1)
- agricultural landscapes (1)
- agriculture (1)
- agrobacterium tumefaciens (1)
- agroecosystems (1)
- agroforestry systems (1)
- agroinfiltration (1)
- air-liquid interface (1)
- albumins (1)
- alcohol (1)
- aldehydes (1)
- algorithm (1)
- algorithms (1)
- alignment (1)
- allelic variant (1)
- alliance (1)
- allopolyploidy (1)
- allostatic load (1)
- alpha (1)
- alpha-globin (1)
- alpha-toxin (1)
- alveolar (1)
- alveolar echinococcosis (1)
- alzheimers disease (1)
- amino acid sequence (1)
- amino acids (1)
- amplification (1)
- amygdala response (1)
- anaerobic and aerobic testing (1)
- anaerobic threshold (1)
- analysis (1)
- ancestor (1)
- ancillary data (1)
- and justice for all (1)
- anemia (1)
- anesthesiologists (1)
- animal behavior (1)
- animal migration (1)
- animal model (1)
- animal sexual behavior (1)
- antagonist (1)
- antagonists (1)
- antennal lobe (1)
- anterior cingulate cortex (1)
- anterior insula (1)
- anti-biofilm (1)
- anti-schistosomal activity (1)
- antibacterial (1)
- antibacterial/antiviral drug (1)
- antibiotic production (1)
- antibiotic prophylaxis (1)
- antibiotic resistance (1)
- antibody production (1)
- antigen (1)
- antimicrobial activity (1)
- antimicrobial peptides (1)
- antisense RNA (1)
- anxiety disorders (1)
- anxiety sensitivity (1)
- anxiety-like behavior (1)
- anyons (1)
- apis mellifera (1)
- apixaban (1)
- apoE (1)
- apoe (1)
- apoptosis, Myc (1)
- approach and avoidance (1)
- approach-avoidance behavior (1)
- aqueous medium (1)
- aqueous solution (1)
- arachidonic acid (1)
- areas (1)
- arm flexion (1)
- arms (1)
- armyworm Lepidoptera (1)
- arousal (1)
- articulation (1)
- artificial membrane-permeability (1)
- ash (1)
- assemblages (1)
- assistive device (1)
- associated production (1)
- association studies in genetics (1)
- asthmatic bronchial epithelium (1)
- astrocytes (1)
- astrocytoma (1)
- asymmetry (1)
- atherosclerosis (1)
- atherosclerosis risk (1)
- atom (1)
- atomic gases (1)
- atrial fibrillation (1)
- attention deficit/hyperactivity disorder (1)
- atypical (1)
- auditory (1)
- auditory BCI (1)
- auditory brain-computer interface (1)
- autoimmune diseases (1)
- autoimmune neuroinflammation (1)
- autologous transplantation (1)
- automated external defibrillators (1)
- automated map labeling (1)
- automatic evaluation (1)
- automatische Beschriftungsplatzierung (1)
- autonomous (1)
- autopolyploidy (1)
- auxins (1)
- avascular necrosis (1)
- awareness (1)
- axonal damage (1)
- axonal injury (1)
- axonal transport (1)
- axonally transported proteins (1)
- axons (1)
- bacillus subtilis (1)
- backpack mobile mapping (1)
- bacteria (1)
- bacterial biofilms (1)
- bacterial invasion (1)
- bacterial lipoproteins (1)
- bacterial pathogens (1)
- bacteriorhodopsin (1)
- bacterium Legionella pneumophila (1)
- bagworms Lepidoptera (1)
- balance (1)
- balance hypothesis (1)
- bale mountains national park (1)
- balloon kyphoplasty (1)
- band SAR data (1)
- bariatric surgery (1)
- bark beetles (1)
- barrier (1)
- barrier integrity (1)
- barrier properties (1)
- base excision repair (1)
- bax (1)
- bead models (1)
- beetle horns (1)
- behavioral conditioning (1)
- beige adipocytes (1)
- benchmarking (1)
- beta cell function (1)
- beta oscillations (1)
- beta-aminopropionitrile (1)
- beta-catenin (1)
- beta-diveristy (1)
- beta-lactamase inhibition (1)
- beta-lactamases (1)
- beyond Standard Model (1)
- biased dispersal (1)
- bile duct (1)
- biliopancreatic diversion (1)
- binding protein (1)
- binding protein HFQ (1)
- binge eating (1)
- biochemical simulations (1)
- biocide polyhexamethylene biguanide (1)
- biodegradable polymer (1)
- biodegradable polymers (1)
- biodiversity hotspot (1)
- biodiversity-ecosystem functioning (1)
- bioinformatics and computational biology (1)
- biological activity (1)
- biological control (1)
- biological pest control (1)
- biologische Körperflüssigkeiten (1)
- biology (1)
- biomaterial surfaces (1)
- biopharmaceuticals (1)
- biosynthesis (1)
- birth cohort (1)
- blastocysts (1)
- blood brain barrier (1)
- blood coagulability (1)
- blood flow (1)
- blood fluke (1)
- blood lactate (1)
- blood lipids (1)
- blood lymphocytes (1)
- blood pressure (1)
- blood-glucose (1)
- boat conformation (1)
- body weight (1)
- body-size (1)
- bola-amphiphile (1)
- bone (1)
- bone cement (1)
- bone colonization (1)
- bone formation (1)
- bone marrow failure syndrome (1)
- bone regeneration (1)
- bone-disease (1)
- bood (1)
- bortezomib (1)
- boson (1)
- boundary cap (1)
- bovine lactoferricin (1)
- bradykinesia (1)
- brain activation (1)
- brain computer interface (1)
- brain development (1)
- brain dynamics (1)
- brain metastases (1)
- brain potentials (1)
- brain reactivity (1)
- brain tumors (1)
- brain-computer interfaces (1)
- branding (1)
- breaking (1)
- breast cancer cells (1)
- breath-hold (1)
- breathing (1)
- brush cell (1)
- brushite cement (1)
- buildings (1)
- burkholderia cenocepacia (1)
- burning pain (1)
- cAMP (1)
- cEND (1)
- cGMP (1)
- cabbage Brassica oleracea var. capitata (1)
- calcareous grassland (1)
- calcitonin (1)
- calcium level (1)
- calcium phosphate cements (1)
- calibration and validation (1)
- calpain (1)
- camponotus floridanus (1)
- canal surgery (1)
- canaloplasty (1)
- cancer cell lines (1)
- cancer patients (1)
- cancer surveillance (1)
- cancer-targeted IL-12 (1)
- candida genome database (1)
- canine cancer cell lines (1)
- canine cancer therapy (1)
- canine soft tissue sarcoma (CSTS) (1)
- cannons (1)
- capability (1)
- capacity (1)
- capture-mark-recapture (1)
- carbon (1)
- carbon dioxide avoidance (1)
- carbon nanotubes and fullerenes (1)
- carbonaria (1)
- carbonmonoxide (1)
- carcinoma (1)
- carcinoma cells (1)
- carcinoma metastases to pancreas (1)
- cardiac magnetic resonance imaging (1)
- cardiac neurohormonal system (1)
- cardiac surgery (1)
- cardio-pulmonary resuscitation (1)
- cardiovascular arousal (1)
- cardiovascular diseases (1)
- cardiovascular events (1)
- cardiovascular magnetic resonance (1)
- cardiovascularm disease (1)
- carpenter ant (1)
- carrier transport (1)
- carrying capacity (1)
- carvacrol (1)
- case fatality rates (1)
- caspase activation (1)
- cataract surgery (1)
- ce compounds (1)
- celiac disease (1)
- cell (1)
- cell adhesion (1)
- cell binding assay (1)
- cell culture (1)
- cell cultures (1)
- cell cycle arrest (1)
- cell fate (1)
- cell fusion (1)
- cell lung cancer (1)
- cell size (1)
- cell stretch (1)
- cellular camp (1)
- cellular physiology (1)
- cellular senescence (1)
- central asia (1)
- centrality (1)
- cepedia complex (1)
- cerebellum (1)
- cerebral aspergillosis (1)
- cerebral asymmetry (1)
- cerebral calcification (1)
- cerebral cortex (1)
- cerebral gliomas (1)
- cerebral ischemia (1)
- cerebrospinal fluid (1)
- cervical dystonia (1)
- chalcogenides (1)
- channel (1)
- channelrhodopsin-2 (1)
- charge transport (1)
- charge-separated state (1)
- charged aerosol detector (1)
- charged heavy long-lived particles (1)
- chargino (1)
- chemotherapy (1)
- chest-compression rate (1)
- chewed (1)
- childhood asthma (1)
- chip-seq (1)
- chirality-sensitive spectroscopy (1)
- chlamydia infection (1)
- chlamydia trachomatis (1)
- cholinergic (1)
- chondrodysplasia (1)
- chondrosarcoma (1)
- chordotonal organs (1)
- chromatin mobility (1)
- chromosome 11Q13 (1)
- chromosome staining (1)
- chronic cerebrovascular disease (1)
- chronic distress (1)
- chronic heart failure (CHF) (1)
- chronic hepatitis C (1)
- chronic social stress (1)
- chronic thromboembolic pulmonary hypertension (1)
- chronic viral infection (1)
- cigarette smokers (1)
- cigarette smoking (1)
- cinematographic analysis (1)
- circadian rhythms (1)
- circular arc polygon domain (1)
- circular dichroism spectroscopy (1)
- circulating micrornas (1)
- circumferential viscodilation (1)
- circumplex model (1)
- cirrhosis (1)
- cities (1)
- citral (1)
- citrus (1)
- classical conditioning (1)
- clavicular fracture (1)
- click chemistry (1)
- climate change impact (1)
- clinical application (1)
- clinical manifestations (1)
- clinical risk score (1)
- clinical trial (1)
- clock reproduction ecology (1)
- cloning of putative human promoter sequence (1)
- cluster dynamical mean-field theory (1)
- co-immunoprecipitation (1)
- coated vesicles (1)
- coefficient (1)
- cofactors (biochemistry) (1)
- coffin-lowry-syndrome (1)
- cognitive bias (1)
- cognitive control (1)
- cognitive function (1)
- coherence (1)
- coherent control (1)
- coincidence (1)
- collision avoidance (1)
- colloids (1)
- colonialism (1)
- colony morphotypes (1)
- colony-stimulating factor (1)
- color discrimination (1)
- colour flow (1)
- combination testing (1)
- combination therapy (1)
- comet assay (1)
- communication systems (1)
- communities (1)
- community (1)
- community composition (1)
- community functional-responses (1)
- compartment boundary (1)
- compatibility (1)
- complete genome sequence (1)
- complex chromosome rearrangements (1)
- complex networks (1)
- complex traits (1)
- components (1)
- compound eye (1)
- comprehensive psychosomatic assessment (1)
- compressive strength (1)
- computational prediction (1)
- computational systems biology (1)
- computer-assisted instruction (1)
- concomitant radiotherapy (1)
- confinement-deconfinement transition (1)
- conformal mapping (1)
- conjugated honeycomb-chained-trimer (1)
- consensus conference (1)
- consensus statement (1)
- consortium (1)
- consumers (1)
- context effects (1)
- contributes (1)
- control profiles (1)
- control strain (1)
- cooperation (1)
- cooperativity (1)
- coordination polymers (1)
- copy number (1)
- coronary artery disease (1)
- corporate groups (1)
- correlation (1)
- corrupt organizational culture (1)
- corruption (1)
- cortex (1)
- cortical OAT1 (1)
- cortical activation (1)
- cortical magnification factor (1)
- cortical oscillatory activity (1)
- cortical pathology (1)
- corticosteroids (1)
- cost-effectiveness (1)
- costs (1)
- cotransporter SGLT1 (1)
- coupling strength (1)
- crab pulsar (1)
- craving (1)
- cravings (1)
- creatinine (1)
- crop harvest (1)
- cropping systems (1)
- cross-country skiers (1)
- cross-link repair (1)
- cross-lock (1)
- cross-ownership (1)
- cruzi (1)
- crystal (1)
- crystal scructure (1)
- ctr (1)
- cultural differences (1)
- cutaneous adverse events (1)
- cutaneous lupus erythematosus (1)
- cuticular profiles (1)
- cutting edge (1)
- cycle (1)
- cyclists (1)
- cyclodextrin formulations (1)
- cylindrical micelles (1)
- cystic fibrosis (1)
- cytoarchitectonic maps (1)
- cytochrome P450 2C9 (1)
- cytokine (1)
- cytokine expression (1)
- cytokine production (1)
- cytokine profiling (1)
- cytokine secretion kinetics (1)
- cytokines (1)
- cytokinins (1)
- cytolysis (1)
- cytomegalovirus (1)
- cytosolic pH (1)
- c‐Myc (1)
- dRNA-Seq (1)
- dSTORM (1)
- damage (1)
- damaged DNA (1)
- danazol (1)
- dangerous world (1)
- darbepoetin alpha (1)
- dark matter (1)
- data (1)
- data acquisition (1)
- database (1)
- day length (1)
- death pathway sar locus (1)
- deaths (1)
- decays (1)
- decline (1)
- decompensated heart failure (1)
- deep brain stimulation (1)
- deepSuperSAGE (1)
- defects (1)
- defense and evasion strategies (1)
- defenses (1)
- deficit hyperactivity disorder (1)
- degeneration (1)
- deletion 17P (1)
- delineation (1)
- dendritic growth (1)
- density functional theory (1)
- dentate gyrus (1)
- dependence (1)
- derivatives (1)
- dermatitis (1)
- determinants (1)
- determination locus (1)
- determining genes (1)
- detoxification (1)
- development policy (1)
- developmental plasticity (1)
- diabetic kidney disease (1)
- diagnostic accuracy (1)
- diagnostics (1)
- dialysis (1)
- diboson production (1)
- dicholine succinate (1)
- difference water index (1)
- differentially expressed genes (1)
- differentiated thyroid tumor (1)
- diffraction (1)
- diffraction limit (1)
- diffusion (1)
- diffusion weighted MRI (1)
- dihydrate cement (1)
- dimensions (1)
- dimethyl fumarate (1)
- diphoton decay (1)
- diploidization (1)
- direct oral anticoagulants (1)
- direct thrombin inhibitor (1)
- direction selectivity (1)
- discovery (1)
- discrete-to-continuum (1)
- disease comorbidities (1)
- disease severity (1)
- disease-modifying therapy (1)
- disorders (1)
- disorders of consciousness (1)
- dispersal (1)
- disruption project (1)
- dissection (1)
- dissociation (1)
- distance measurement (1)
- distant metastases (1)
- diversity (1)
- division of labor (1)
- dodder (1)
- dolutegravir (1)
- domain K\(^{+}\) channels (1)
- domain genes A3(2) (1)
- domain potassium channels (1)
- dominant (1)
- donor-photosensibilisator-acceptor triad (1)
- dopamine (1)
- dose response (1)
- double-blind (1)
- downconversion (1)
- downstream (1)
- droplet epitaxy (1)
- drosophila larvae (1)
- drug delivery (1)
- drug development (1)
- drug-delivery systems (1)
- drugs (1)
- du Pan dysplasia (1)
- dual setting (1)
- duodenal jejunal bypass (1)
- dyes (1)
- dysfunction (1)
- dysphagia (1)
- dysplasia (1)
- dünner Filme (1)
- early onset sepsis (1)
- early stage (1)
- early-stage osteonecrosis (1)
- ecological relevant model (1)
- efficacy (1)
- efficiency (1)
- elastic fibers (1)
- elastin (1)
- electrolytes (1)
- electromyographic activity (1)
- electron density (1)
- electron tomography (1)
- electronic properties and materials (1)
- electrooculography (1)
- electrophysiology (1)
- electrospinning (1)
- electroweak production (1)
- elements (1)
- elevated plus-maze (1)
- elevator EMG activity (1)
- elispot (1)
- elongation (1)
- embodiment (1)
- embryonic stem cells (1)
- emotion regulation (1)
- emotional eating (1)
- emotional empathy (1)
- emotional experience (1)
- emotional responses (1)
- emphysema (1)
- employees' corruption (1)
- emtricitabine (1)
- enal impairment (1)
- encephalitis dementia (1)
- end-stage renal disease (1)
- end-stage renal failure (1)
- endocytic multivesicular bodies (1)
- endocytosis (1)
- endoplasmic reticulum (1)
- endoprothesis (1)
- endothelin-1 (1)
- endotoxemia (1)
- energetic jet (1)
- energy transfer dynamics (1)
- entanglement (1)
- enteric pathogens (1)
- enterica serovar Typhimurium (1)
- enterica serovar thphimurium (1)
- enteroendocrine cells (1)
- entorhinal cortex (1)
- entrainment (1)
- envelopment (1)
- environment interaction (1)
- environmental enrichment (1)
- environments (1)
- enzyme assays (1)
- enzyme metabolism (1)
- enzyme replacement therapy (1)
- epidemology (1)
- epidermal growth factor (1)
- epigenetics (1)
- epigenomic landscapes (1)
- epithelial cell culture (1)
- erectile dysfunction (1)
- ereigniskorrelierte Potentiale (1)
- ergodic transformation (1)
- eruption rate (1)
- erweiterte Eichsymmetrie (1)
- erythropoiesis-stimulating agents (1)
- esophagogastric junction (1)
- esophagoscopy (1)
- essential oils (1)
- essential tremor (1)
- ether (1)
- ethers (1)
- etomidate (1)
- eucalyptus (1)
- eugenyl cinnamate (1)
- eukaryotic gene expression (1)
- european beech forests (1)
- european countries (1)
- evaluation (1)
- evapotranspiration (1)
- event-related desynchronization (1)
- event-related fMRI (1)
- events (1)
- ex vivo expansion (1)
- excimer formation (1)
- excitation-secretion coupling (1)
- exciton (1)
- exercise therapy (1)
- exhaustion (1)
- exome (1)
- expectancy (1)
- experimental visceral leishmaniasis (1)
- expertise (1)
- explosive volcanism (1)
- exposure therapy (1)
- expression analysis (1)
- expression mutants (1)
- expression signature (1)
- expressive displays (1)
- extended gauge symmetry (1)
- extinction (1)
- extra Eichbosonen (1)
- extra gauge bosons (1)
- extrapulmonary (1)
- eye tracking (1)
- eyes (1)
- fMRI (1)
- face perception (1)
- face processing (1)
- face recognition (1)
- facial affect (1)
- facial electromyography (1)
- facial expression (1)
- facial muscle contractions (1)
- factor B (1)
- factor Sox10 (1)
- factor XA inhibitor (1)
- factor binding profiles (1)
- factor expression (1)
- familiarity (1)
- family (1)
- fat development (1)
- fatty liver disease (1)
- fear avoidance model (1)
- features (1)
- femtosecond pulse shaping (1)
- femtosecond spectroscopy (1)
- ferritin (1)
- fetal lung (1)
- fiber reinforcement (1)
- fibrinogen (1)
- fibroblast growth factor-23 (1)
- fibromyalgia syndrome (1)
- fibronectin-binding protein (1)
- field (1)
- field flow fractionation (1)
- filaggrin mutations (1)
- financial network (1)
- finanzielles Netzwerk (1)
- finite elements (1)
- firm valuation (1)
- fish (1)
- fishes Xiphophorus (1)
- flagellar motility (1)
- flexibility (1)
- flexible microcatheter (1)
- flies (1)
- flight phobics (1)
- flood detection (1)
- flood hazard index (1)
- flow (1)
- flow cytometry (1)
- flowers (1)
- fluctuation theorem (1)
- fluid (1)
- fluorescein isothiocyanate (1)
- fluorescence-detected sedimentation (1)
- fluorescent (1)
- flux (1)
- focal cerebral ischemia (1)
- foci (1)
- food addiction (1)
- food allergy (1)
- food industry (1)
- food intake (1)
- forests (1)
- format (1)
- formulations (1)
- fourier transform spectroscopy (1)
- fracture (1)
- fraxe mental retardation (1)
- free choice (1)
- fruit set (1)
- fully hadronic (1)
- functional analysis (1)
- functional characterization (1)
- functional magnetic resonance imaging (1)
- functional modules (1)
- fungal infections (1)
- fungal pathogens (1)
- gadoxetic acid (1)
- gain (1)
- galactomannan (1)
- gall bladder (1)
- gametes (1)
- gametocyte (1)
- gamma astronomy (1)
- gamma knife radiosurgery (1)
- gamma-convergence (1)
- gas (1)
- gastrointestinal cancer (1)
- gating (1)
- gefitinib (1)
- gender differences (1)
- gene conversion (1)
- gene expression profiling (1)
- gene locus (1)
- gene mutations (1)
- gene ontology (1)
- gene regulation (1)
- gene regulator agr (1)
- gene-by-environment interaction (1)
- gene-environment interaction (1)
- general anaesthesia (1)
- genetic interaction networks (1)
- genetic modifiers (1)
- genetic variation (1)
- genome (1)
- genome browser (1)
- genome cells (1)
- genome instability (1)
- genome wide (1)
- genome-wide association study (1)
- genomewide association (1)
- genomic analysis (1)
- genomic islands (1)
- genus (1)
- genus Xiphophorus (1)
- geographical information system (1)
- germination (1)
- giant pulses (1)
- glaucoma (1)
- glial cells (1)
- glioblastoma (1)
- glioblastoma stem cell (1)
- glioma (1)
- gliomas (1)
- global gene expression (1)
- global outcomes (1)
- glomerular filtration rate (1)
- glucagon like peptide-1 (1)
- glucose control (1)
- glutamate receptor (1)
- glycaemic control (1)
- glycerol (1)
- glycine receptor (1)
- glycogen synthase kinase-3β (1)
- glycolipids (1)
- glycolysis (1)
- goldfish optic nerve (1)
- gonopodium (1)
- graded activity (1)
- gram-negative bacteria (1)
- grand unification (1)
- grebe (1)
- gridle muscular-dystrophy (1)
- grounded cognition (1)
- group consensus statement (1)
- growth and differentiation factor 5 (1)
- growth factor (1)
- growth-associated protein (1)
- growth-factor receptor 3 (1)
- guideline adherence (1)
- guides (1)
- gut hormones (1)
- habits (1)
- hadron colliders (1)
- hadronic decays (1)
- haemodiafiltration (1)
- halstedii JM8 (1)
- haplogroups (1)
- haploinsufficiency (1)
- hay fever (1)
- haze (1)
- hcv infection (1)
- head (1)
- head and neck cancer (1)
- head-mounted display (1)
- health (1)
- health care workers (1)
- health economics (1)
- healthy volunteers (1)
- hearing (1)
- heart valve (1)
- heat waves (1)
- helical liquid (1)
- helicopters (1)
- hemodiafiltration (1)
- hemodialysis (1)
- hemoglobin (1)
- hepatitis B (1)
- hepatitis B virus (1)
- hepatitis C virus (1)
- heptaocytes (1)
- heralded entanglement (1)
- herbivores (1)
- herbivorous insects (1)
- herpes simplex virus (1)
- heterogamety (1)
- heterogeneity (1)
- heterogenity (1)
- heterologous production (1)
- heterosis (1)
- hexaarylbenzenes (1)
- high energy (1)
- high intensity training (1)
- high risk (1)
- high throughput sequencing (1)
- high transverse momentum jets (1)
- high volume (1)
- high-energy collider experiment (1)
- high-risk cytogenetics (1)
- higher order methods (1)
- hippocampal plasticity (1)
- hippocampal stem cells (1)
- hippocampal-neurons (1)
- histidine kinases (1)
- histology (1)
- histopathology (1)
- hnRNP K (1)
- home telemonitoring (1)
- homoeologous chromosomes (1)
- homologous recombination (1)
- honey bees (1)
- hopping model (1)
- host cells (1)
- host pathogen interaction (1)
- host pathogen interactions (1)
- host-pathogen adaption (1)
- host-pathogen interaction (1)
- hotspots (1)
- hubbard-model (1)
- human (1)
- human A(3) (1)
- human atherosclerotic lesions (1)
- human cytomegalovirus (HCMV) (1)
- human dendritic cells (1)
- human hepatic cells (1)
- human heptocytes (1)
- human immune system (1)
- human immunodeficiency virus (1)
- human macrophages (1)
- human melanoma (1)
- human muscle-cells (1)
- human orbitofrontal cortex (1)
- human osteosarcoma xenografts (1)
- human pathogen (1)
- human pathogenic fungi (1)
- human-immunodeficiency-virus (1)
- humanized bone models (1)
- humanized mice (1)
- humans (1)
- hybrid origin (1)
- hybrid systems (1)
- hybridization (1)
- hybridogenesis (1)
- hybrids (1)
- hydrochloride (1)
- hydrodynamics (1)
- hydrogen bonding (1)
- hydrogen bonding mycobacterium tuberculosis (1)
- hymenoptera (1)
- hyperekplexia (1)
- hyperoxia (1)
- hyperpolarized HE-3 (1)
- hypertrophic cardiomyopathy (1)
- hypotonic (1)
- hypotonic solutions (1)
- hypoxia (1)
- hypoxia inducible factor 1 (1)
- hypoxia-independent (1)
- i-131 uptake (1)
- iNKT (1)
- idiopathic inflammatory myopathies (1)
- idiopathic osteonecrosis (1)
- illumina MiSeq platform (1)
- illumination microscopy (1)
- illusory correlation (1)
- image (1)
- imaginal disk (1)
- imaging mass spectrometry (1)
- imaging techniques (1)
- immersion (1)
- immpact recommendations (1)
- immune (1)
- immune cell function (1)
- immune cells (1)
- immune escape (1)
- immune system (1)
- immune thrombocytopenia (1)
- immunization (1)
- immuno suppression (1)
- immuno-magnetic purification (1)
- immunocompromised patients (1)
- immunocytokine (1)
- immunodeficiency (1)
- immunohistochemistry (1)
- immunological cross-talk (1)
- immunoprecipitation (1)
- immunoresistance (1)
- immunostaining (1)
- immunosurveillance (1)
- impact pharmacogenetics (1)
- implantation (1)
- implementation (1)
- implicit attitude measurement (1)
- import (1)
- improvement (1)
- improves (1)
- in vitro models (1)
- in vivo formation (1)
- in vivo polycomb (1)
- in-hospital cardiac arrest (1)
- inactivation (1)
- incompatible interaction (1)
- increased risk (1)
- incremental cost-effectiveness ratio (ICER) (1)
- independence (1)
- independent marker (1)
- indicators (1)
- individual radiosensitivity (1)
- induced (1)
- induced apoptosis (1)
- induced phase transition (1)
- inducible nitric oxide synthase (1)
- induction (1)
- inertial idiothetic navigation (1)
- inferior parietal lobule (1)
- infiltration (1)
- inflammatory diseases (1)
- inflammatory pain (1)
- influenza (1)
- influenza A virus (1)
- information (1)
- information engine (1)
- infrared (1)
- infrared detectors (1)
- infrasound (1)
- inhibit (1)
- inhibitor (1)
- initial experience (1)
- initiation (1)
- initio molecular dynamics (1)
- injection site reactions; (1)
- injury (1)
- inpatient rehabilitation (1)
- insect (1)
- insect populations (1)
- insect timing (1)
- instinct (1)
- insufficiency (1)
- insulators (1)
- insulin receptor (1)
- intake (1)
- integral (1)
- integrase inhibitor (1)
- integrative genomics viewer (1)
- integrins (1)
- intensive care (1)
- interactive maps (1)
- interferon-\(\beta\) (1)
- intergroupe francophone (1)
- interleukin-4 (1)
- intermediate host snail (1)
- intermixing (1)
- internalization (1)
- international union (1)
- interolog (1)
- intestinal absorption (1)
- intestinal glucose (1)
- intestine (1)
- intracellular bacteria (1)
- intracellular pH (1)
- intracellular replication (1)
- intracerebral hemorrhage (1)
- intrahelical lesion (1)
- inverse photoemission (1)
- iodine nutrition (1)
- iohexol (1)
- ionic selectivity (1)
- iridium complex (1)
- iron homeostasis (1)
- iron pnictides (1)
- irridation (1)
- ischaemic stroke (1)
- ischemia (1)
- ischemic acute kidney injury model (1)
- isoforms (1)
- isotonic (1)
- isotopolog profiling (1)
- issues (1)
- italian patients (1)
- ivory coast (1)
- janus kinase inhibitor (1)
- jet energy scale (1)
- jet production (1)
- jets (1)
- josephson junction (1)
- judgements (1)
- judgments (1)
- jump height (1)
- juvenile idiopathic arthritis (1)
- juvenile myoclonic epilepsy (1)
- kallikrein-kinin system (1)
- kappa-B (1)
- key innovation (1)
- kidney function (1)
- kinase inhibitor (1)
- kinesin (1)
- knockout mice (1)
- knowledge engineering (1)
- korrupte Organisationskultur (1)
- land use intensification (1)
- land-atmosphere interaction (1)
- land-cover classification (1)
- land-use intensity (1)
- landscape ecology (1)
- large gene lists (1)
- large-scale climate circulation (1)
- late positive potential (1)
- lateral geniculate-nucleus (1)
- lattice (1)
- lead-lead collision (1)
- learned helplessness (1)
- learning (1)
- learning-by-doing (1)
- left lateral wall (1)
- left ventricular hypertrophy (1)
- leishmania (1)
- leishmaniasis (1)
- length (1)
- lepton flavour violation (1)
- leukemia (1)
- leukocytes (1)
- level mechanical vibrations (1)
- lexical decision task (1)
- life history (1)
- life span (1)
- ligand (1)
- ligand CD55 (1)
- ligand potencies (1)
- ligand-receptor complex (1)
- ligation (1)
- limited mobility (1)
- line (1)
- linear combination (1)
- linguistic markedness (1)
- linkage analysis (1)
- linkage map (1)
- lipid bilayer membranes (1)
- listeria monocytogenes (1)
- literary studies (1)
- liver microsomes (1)
- local density (1)
- local supersymmetry (1)
- localization (1)
- localized wannier functions (1)
- loci (1)
- locked-in state (1)
- long noncoding RNA (1)
- long-distance dispersal (1)
- long-lived neutral particle (1)
- long-term potentation (1)
- long-term potentiation (1)
- loop B (1)
- loop region (1)
- low intensity (1)
- lowering lattice forces (1)
- luciferase (1)
- luminescence crystal structure (1)
- lung (1)
- lymphadenitis (1)
- lymphocytes (1)
- lymphokine-activated killer (1)
- lysine biosynthesis (1)
- mRNA metabolism (1)
- mRNA-Seq (1)
- magnetic field relaxation (1)
- magnetic-resonance behavior (1)
- magnitude (1)
- maintain immune homeostasis (1)
- maize (1)
- major depression (1)
- major depressive disorder (1)
- major histocompatibility complex (1)
- male-specific traits (1)
- males (1)
- males emerge (1)
- malignancies (1)
- malignant lymphoma (1)
- malignant melanoma (1)
- man-portable mapping (1)
- managed grasslands (1)
- manganese (1)
- mangrove ecosystems (1)
- mapping (1)
- marine Synechococcus strains (1)
- marrow (1)
- masked priming (1)
- mass (1)
- mass vaccination (1)
- match-mismatch (1)
- materials design (1)
- maternal care (1)
- mating success (1)
- matrix metalloproteinases (1)
- matrix protein porin (1)
- maximum oxygen uptake (1)
- maximum power (1)
- mean-field theory (1)
- mechanical properties (1)
- mechanism (1)
- mechanisms retention (1)
- medial temporal lobe (1)
- medical Education (1)
- medical complications (1)
- medical hypoxia (1)
- medical rehabilitation (1)
- medicine (1)
- medullary thyroid cancer (1)
- mekong delta (1)
- melanin (1)
- melanocytes (1)
- melanocytic nevi (1)
- melanogenesis (1)
- melanoma cancer (1)
- melanoma patients (1)
- melanomas (1)
- mellitus (1)
- membrane (1)
- membrane potential (1)
- membrane receptor signaling (1)
- membrane repair (1)
- membrane vesicles (1)
- memory B cells (1)
- memory cells (1)
- memory deficits (1)
- memory formation (1)
- memory immune responses (1)
- men born (1)
- mental representation (1)
- mepacrine (1)
- mercury (1)
- mere exposure (1)
- merozoite (1)
- mesoscopic physics (1)
- mesoskopische Physik (1)
- messenger-RNA (1)
- messenger-RNA transport (1)
- metabolites (1)
- metabolomics (1)
- metachronous (1)
- metacognitive prompting (1)
- metagenomic (1)
- metal carbonyl (1)
- metal surfaces (1)
- metal-insulator transition (1)
- metal-organic frameworks (1)
- metallosupramolecular π-amphiphiles (1)
- metaphors (1)
- metastasis (1)
- metastatic melanoma (1)
- methionine pet (1)
- methotrexate (1)
- mhc molecules (1)
- miR-122 (1)
- miR-181 (1)
- miRNAs (1)
- mice impact (1)
- micro-photoluminescence (1)
- microRNA (1)
- microbial communities (1)
- microbial rhodopsins (1)
- microcephalin 1 (1)
- microelectrodes (1)
- microglia (1)
- microglial cells (1)
- microneme (1)
- micronucleus test (1)
- microscopy (1)
- microsphere/macrosphere (1)
- microstructures (1)
- microvascular complications (1)
- mid-infrared (1)
- migraine (1)
- migration (1)
- mimicry (1)
- mineral metabolism (1)
- mineralization (1)
- mismatch recognition (1)
- missense (1)
- mitochondrial biogenesis (1)
- mitochondrial membrane (1)
- mitochondrial transport (1)
- mitogenic signaling (1)
- mitomycin C (1)
- mitosis (1)
- mixed fiber neuropathy (1)
- mixed mutation mechanisms (1)
- miyoshi myopathy (1)
- mobile laser scanning (1)
- mobility (1)
- mode (1)
- model Bessel function (1)
- model calculation (1)
- moderating role (1)
- moderation (1)
- modifiers (1)
- modulates virulence (1)
- mold disease (1)
- molecular analysis (1)
- molecular basis (1)
- molecular characterization (1)
- molecular cloning (1)
- molecular data (1)
- molecular docking (1)
- molecular liphophilicity potential (1)
- molecular mechanisms (1)
- molecules (1)
- monkey striate cortex (1)
- mono-temporal image (1)
- monoclonal antibodies (1)
- monoclonal antibody (1)
- monomethyl fumarate (1)
- monoubiquitination (1)
- months follow-up (1)
- mood (1)
- morphogenetic furrow progression (1)
- morphometry (1)
- morris water maze (1)
- mortality rates (1)
- mothers (1)
- moths and butterflies (1)
- motif discovery (1)
- motifs (1)
- motoneuron (1)
- motor axons (1)
- motor cortex activation (1)
- motor imagery technology (1)
- motor-impaired end-user (1)
- mott insulator (1)
- mouse (1)
- mouse brain (1)
- mouse lymphoma L5178Y (1)
- mouse testis differentiation (1)
- mrsk2 KO mouse (1)
- multi scale heterogeneity (1)
- multi-electrode-recording (1)
- multi-temporal images (1)
- multidetector computed-tomography (1)
- multilocularis (1)
- multimedia, (1)
- multiparametric flow cytometry (1)
- multiparticle collision dynamics (1)
- multiple diseases (1)
- multiple-sclerosis (1)
- multiply connected domain (1)
- multitemporal ALOS/PALSAR imagery (1)
- multiwalled carbon nanotube (1)
- murine model (1)
- mutagenicity (1)
- mutants (1)
- mutation (1)
- mutual information (1)
- myocarditis (1)
- nanoactivity (1)
- nanolithography (1)
- nanostructures (1)
- nanowire (1)
- native bees (1)
- natriuretic peptide levels (1)
- natural enemies (1)
- natural history (1)
- natural products (1)
- natural variation (1)
- navigation (1)
- near-field monitoring (1)
- neck cancer (1)
- necrosis factor alpha (1)
- nectar (1)
- negative affect (1)
- neoblast (1)
- nesting behaviour (1)
- network (1)
- network inference (1)
- networks (1)
- neural mechanisms (1)
- neural response (1)
- neural stem cell (1)
- neuregulin-1 (1)
- neurite outgrowth (1)
- neurodegeneration (1)
- neurodevelopmental disorders (1)
- neurogenesis (1)
- neuron navigator 3 (1)
- neurons (1)
- neuropathy (1)
- neuroprotection (1)
- neutralino (1)
- neutron star (1)
- neutropenic fever (1)
- new physics (1)
- new species (1)
- newly-diagnosed myeloma (1)
- niche (1)
- nicotinamide phosphoribosyltransferase (1)
- nicotine addiction (1)
- nociceptors (1)
- nomenclature (1)
- non-VKA oral anticoagulants (1)
- non-covalent interactions (1)
- non-penetrating glaucoma surgery (1)
- nonautonomous (1)
- nonconscious mimicry (1)
- nonhuman-primates (1)
- nonneuronal acetylcholine (1)
- nontraumatic osteonecrosis of the femoral head (1)
- normal distribution (1)
- norway spruce (1)
- nosocomial infection (1)
- nosocomial pathogen (1)
- novel nepetolactone derivative (1)
- novo renal transplantation (1)
- nuclear cardiology (1)
- nuclear envelope (1)
- nuclear magnetic resonance (1)
- nuclear pore complex (1)
- nucleo-cytoplasmic (1)
- nucleotide-gated channel (1)
- nucleus (1)
- nucleus ventralis intermedius (1)
- number (1)
- numerical cognition (1)
- nutrition (1)
- nutzerzentrierter Ansatz (1)
- obesity (1)
- obstacle detection (1)
- obstructive pulmonary disease (1)
- occupational-status (1)
- ocular dominance columns (1)
- odorants (1)
- oilseed rape (1)
- olfactory bulb (1)
- oligo(phenylene ethynylene) (OPE) (1)
- oligomers (1)
- on-a-chip (1)
- oncogene amplification (1)
- oncogene-induced senescence (1)
- oncogenes (1)
- oncolysis (1)
- oncolytic virotherapy (1)
- oncolytic virus (1)
- oncolytic virus therapy (1)
- onkolytische Virustherapie (1)
- online advertising (1)
- open-access database (1)
- open-angle glaucoma (1)
- opioid receptors (1)
- opossum kidney cells (1)
- optical control (1)
- optical lattice (1)
- optical reconstruction microscopy (1)
- optical spectroscopy (1)
- optimal control (1)
- optimize performance (1)
- oragnoids (1)
- oral bioavailability (1)
- oral mucositis (1)
- organic solar cell (1)
- organic thin films (1)
- organic transistor (1)
- organisationale Korruption (1)
- organische Solarzelle (1)
- organischer Transitor (1)
- organismal evolution (1)
- organization (1)
- organizational corruption (1)
- orientation columns (1)
- orthoptera (1)
- oscillations (1)
- osmia (1)
- osteoblastic cells (1)
- osteogenic differentiation (1)
- osteopontin (1)
- outer membrane proteins (1)
- ovarian cancer (1)
- ovarian carcinoma (1)
- ovariectomized rats (1)
- overdose (1)
- overexpression (1)
- oxygen (1)
- oxygen-glucose deprivation (1)
- p38 mitogen-activated protein kinase (1)
- p53 (1)
- paddy (1)
- paddy rice (1)
- pain (1)
- pain questionnaire (1)
- pain-related evoked potentials (1)
- painful (1)
- pair production (1)
- pallidal stimulation (1)
- palynolog (1)
- pancreatic cancer (1)
- panic disorder (1)
- papillary (1)
- paragangliomas (1)
- parasite (1)
- parasites (1)
- parasitic diseases (1)
- parasitic plants (1)
- parathyroid hormone (1)
- paravalvular regurgitation (1)
- parenting stress (1)
- parietal pleurectomy (1)
- parity (1)
- parkinsons disease (1)
- paromomycin (1)
- paroxysmal atrial fibrillation (1)
- partial differetial equations (1)
- particle (1)
- patch connectivity (1)
- pathogen (1)
- pathogen vacuole (1)
- pathogen-host interaction (PHI) (1)
- pathology (1)
- pathology section (1)
- patient survival (1)
- peginterferon alpha-2b (1)
- penalty throw (1)
- pentacene (1)
- performance liquid chromatography (1)
- perfusion (1)
- perioperative chemotherapy (1)
- peripheral blood lymphocytes (1)
- peripheral nerve injury (1)
- peripheral nervous system (1)
- peritoneal carcinomatosis (1)
- permanent and transient middle cerebral artery occlusion (1)
- permutation (1)
- peroral endoscopic myotomy (1)
- peroxiredoxin 6 (1)
- persistence (1)
- persister cells (1)
- personal laser scanning (1)
- perylene bisimide (1)
- pest (1)
- pestis infection (1)
- ph (1)
- phacocanaloplasty (1)
- phacotrabeculectomy (1)
- phagosome maturation arrest (1)
- pharmaceutical analysis (1)
- pharmaceutical applications (1)
- pharmacokinetic (1)
- pharmacokinetic interaction (1)
- pharmacokinetics (1)
- pharmacology (1)
- phase transitions (1)
- phenolic constituents (1)
- phenology shifts (1)
- phenotypic heterogeneity (1)
- phenotypic plasticity (1)
- pheromones (1)
- phobia (1)
- phonation (1)
- phonetic symbolism (1)
- phosphatase 2A (1)
- phosphate homeostasis (1)
- phosphatidic acid (1)
- phosphatidylinositol 3-kinase/Akt (1)
- phosphodiesterase (1)
- phospholipase D (1)
- phosphorus (1)
- phosphorylated glycogen synthase kinase-3beta (pGSK-3beta) (1)
- photodynamic therapy (1)
- photoelectron spectroscopy (1)
- photoelectron-photoion coincidence (1)
- photoemission (1)
- photoemission spectroscopy (1)
- photoinduced electron transfer (1)
- photoinduzierter Elektronentransfer (1)
- photoluminescence (1)
- photonic devices (1)
- photothrombosis (1)
- physical activity (1)
- physics transition (1)
- physiological characteristics (1)
- physiological constraints (1)
- phytochemistry (1)
- phytomedicine (1)
- phytoneering (1)
- placental mammal (1)
- plant cells (1)
- plant diversity (1)
- plant immunity (1)
- plant species richness (1)
- plant-insect interactions (1)
- plant-made vaccines (1)
- plant-plant interaction (1)
- plantations (1)
- plasma clearance (1)
- plasticity (1)
- plastid targeting (1)
- platelet activation (1)
- platelet aggregation (1)
- platelets (1)
- plumes (1)
- pluripotency (1)
- plus dexamethasone (1)
- pneumonia (1)
- pneumonic plague (1)
- podophyllotoxin (1)
- poeciliid fishes (1)
- point labeling (1)
- point-of-care test (1)
- polarimetric SAR (1)
- polarimetry (1)
- polarization pulse shaping (1)
- polarized training (1)
- political leaders (1)
- pollen (1)
- pollination (1)
- pollination ecology (1)
- pollution (1)
- poly(A) site usage (1)
- polyacrylic acid (1)
- polyamine (1)
- polyethylenglykole (1)
- polylactid (1)
- polymer (1)
- polymerization (1)
- polymorphisms inflammation (1)
- polymyositis (1)
- polyploidization (1)
- polyploidy (1)
- pomalidomide (1)
- pooled (1)
- poorly water soluble drugs (1)
- population (1)
- populations (1)
- populations genetics (1)
- porosity (1)
- positive emotions (1)
- positive interneurons (1)
- positron-emission-tomography (1)
- post-pandemic (1)
- posterior parietal cortex (1)
- postoperative care (1)
- postsurgical adhesion (1)
- potassium channels (1)
- potent (1)
- potent inducer (1)
- potential role (1)
- power-station accident (1)
- pre-messenger RNA (1)
- predictive adaptive response hypothesis (1)
- preexisting bias (1)
- preference construction (1)
- prefrontal activity (1)
- prefrontal cortex (1)
- premalignant lesion (1)
- preproteins (1)
- presence (1)
- presence questionnaire (1)
- presynaptic calcium (1)
- presynaptic differentiation (1)
- pretension (1)
- preterm birth (1)
- prevention (1)
- primary cells (1)
- primary microvascular endothelial cells (1)
- primary prophylaxis (1)
- priming (1)
- principal component analysis (1)
- process analysis (1)
- process mining (1)
- processing bias (1)
- productivity (1)
- prognostic marker (1)
- promastigotes (1)
- promoter (1)
- promoter methylation (1)
- proportion of seminatural habitat (1)
- propranolol (1)
- propulsion (1)
- prospective (1)
- prospective feasibility (1)
- prospective randomized trial (1)
- prostaglandin E2 (1)
- prostaglandin e2 (1)
- prostate cancer (1)
- protandry (1)
- protein RSK2 (1)
- protein biomarkers (1)
- protein biosynthesis & quality control (1)
- protein complexes (1)
- protein coupled receptors (1)
- protein domains (1)
- protein expression (1)
- protein interaction database (1)
- protein interactions (1)
- protein-1 CDMP1 gene (1)
- protein-protein interaction (1)
- protein-protein interaction network (1)
- proteinuria (1)
- proton MRI (1)
- proton efflux (1)
- proton-lead collision (1)
- proton-proton collisions (1)
- proton-proton-collisions (1)
- proton-proton-collistion (1)
- proton-prton-collision (1)
- proximity effect (1)
- pseudomas aeruginosa (1)
- pseudomonas aeruginosa (1)
- psoriasis (1)
- psychological stress (1)
- psychophysiology (1)
- public speaking (1)
- pulmonary (1)
- pulmonary drug-delivery (1)
- pulmonary hypertension (1)
- pulmonary wedge resection (1)
- pulsating explosive eruptions (1)
- punishment (1)
- purification (1)
- pyramidal retrospective (1)
- pyridobenzodiazepine (1)
- pyrolysis (1)
- quadrocopter (1)
- quadrotor (1)
- quality of life (1)
- quantification (1)
- quantitative computed tomography (1)
- quantitative remote sensing (1)
- quantitative sensory testing (1)
- quantum dot (1)
- quantum dot systems (1)
- quantum gases (1)
- quantum point contact (1)
- quasi-continuum (1)
- qubits (1)
- quinacrine (1)
- radar (1)
- radiation (1)
- radiation myelitis (1)
- radiation therapy (1)
- radical prostatectomy (1)
- radio astronomy (1)
- radiotracer (1)
- rainforest (1)
- raltegravir (1)
- ramp test (1)
- random walk (1)
- rapid BCI (1)
- rare (1)
- rat brain microvascular endothelial cell culture (1)
- rational model (1)
- rats (1)
- re-annotation (1)
- reaction-time tasks (1)
- reactive intermediates (1)
- reactive oxygen (1)
- reactive oxygen species (1)
- reaktive Intermediate (1)
- real time PCR (1)
- reappraisal (1)
- rebate systems (1)
- receptor (1)
- receptor antagonist (1)
- recognition memory (1)
- recognize images (1)
- recombinant protein rVE (1)
- recombinant proteins (1)
- recombinant-human-erythropoietin (1)
- reconstructed human epidermis (1)
- reconstruction microscopy (1)
- reconstruction plates (1)
- rectal cancer (1)
- recurrence (1)
- recurrence survival (1)
- recurrent Tako-Tsubo cardiomyopathy (1)
- recurrent primary pneumothorax (1)
- red fluorescent protein (1)
- reference values (1)
- reflex (1)
- regeneration (1)
- regenerative medicine (1)
- regional analgesia (1)
- regional development (1)
- register (1)
- registries (1)
- regulation of expression (1)
- regulation strategies (1)
- regulatory networks (1)
- regulatory protein ICP27 (1)
- regurgitation (1)
- relapsing multiple sclerosis (1)
- relapsing-remitting multiple sclerosis (1)
- relaxation (physics) (1)
- relaxation time (1)
- reliability (1)
- religion (1)
- remote (1)
- remyelination (1)
- renal function (1)
- renal replacement therapy (1)
- repeated dose (1)
- reperfusion (1)
- replacement therapy (1)
- replication (1)
- reporter gen assay (1)
- residence time (1)
- resin (1)
- resistant Staphylococcus-aureus (1)
- resistant acid phosphatase (1)
- resolution (1)
- resonances (1)
- resonant inelastic x-ray scattering (1)
- resonant photoelectron spectroscopy (1)
- resource (1)
- respiratory distress syndrome (1)
- respiratory syncytial virus (1)
- response evaluation (1)
- response inhibition (1)
- response priming (1)
- response regulator (1)
- responses (1)
- retinal differentiation (1)
- retrotransposition (1)
- revealed preference (1)
- reward (1)
- rhabdomyosarcoma (1)
- rhodopsin (1)
- riboflavin (1)
- ribosomal RNA (1)
- ribosomal RNA genes (1)
- ribosome (1)
- rice (1)
- rice mapping (1)
- right-oriented bias (1)
- riociguat (1)
- risk profiling (1)
- rivers (1)
- room temperature (1)
- root (1)
- runoff (1)
- s allele (1)
- s-Channel (1)
- salt solutions (1)
- sand dynamics (1)
- scanning tunneling spectroscopy (1)
- schistosoma (1)
- schistosomula (1)
- sciatic nerve (1)
- search filter (1)
- secondary metabolite gene cluster (1)
- secondary metabolites (1)
- secondary prevention (1)
- secondary rainforest fragments (1)
- secretion systems (1)
- selective channel (1)
- self-assembly (1)
- self-diffusion (1)
- self-efficacy (1)
- self-focused attention (1)
- self-organized magnetization (1)
- self‐regulated learning (1)
- semiconductor (1)
- semiconductor interfaces (1)
- semiconductor quantum dots (1)
- senescence (1)
- sensitive amine oxidase (1)
- sensitivity (1)
- sequence alignment (1)
- sequence analysis (1)
- sequencing data (1)
- series (1)
- seroprevalence (1)
- serotonin (1)
- serotonin transporter gene (1)
- serovar Typhimurium (1)
- serum 25-hydroxyvitamin D (1)
- serum amyloid A (1)
- serum creatinine (1)
- sevoflurane (1)
- sex combs (1)
- sex differentiation (1)
- sexual stage (1)
- shaping of porosity (1)
- shear stress (1)
- sheep (1)
- shootin-1 (1)
- short-term-memory (1)
- siRNAs (1)
- sick leave (1)
- side chain properties (1)
- signal transduction (1)
- signal transduction pathway (1)
- signaling pathways (1)
- signalling (1)
- signals (1)
- signature (1)
- silk fibroin (1)
- similarity (1)
- simple receptive-fields (1)
- simulation (1)
- simultaneous (1)
- single cell (1)
- single photon (1)
- single subject (1)
- single-crystalline Ru surfaces (1)
- single-nucleotide polymorphisms (1)
- single-top-quarks (1)
- single-trial EEG classification (1)
- sinorhizobium fredii NGR234 (1)
- site (1)
- situation of women (1)
- size dimorphism (1)
- size exclusion chromatography (1)
- skeletal-muscle (1)
- skin autofluorescence (1)
- skin conductance response (1)
- skin fatty acid (1)
- skin hemagioma (1)
- skin reactions (1)
- skull base (1)
- sleep EEG (1)
- sleeping sickness (1)
- small RNAs (1)
- small bowel MRI (1)
- small regulatory RNAs (1)
- small-colony variants (1)
- smoking motives (1)
- snails (1)
- social anxiety (1)
- social influence (1)
- social network sites (1)
- social phobia (1)
- sodium channels (1)
- sofosbuvir (1)
- software (1)
- soil moisture retrieval (1)
- solid dispersion (1)
- solid state (1)
- solid tumors (1)
- somatic mosaicism (1)
- somatic mutations (1)
- somatostatin (1)
- sound symbolism (1)
- source parameters (1)
- space (1)
- spacer sequences (1)
- spatial filters movement (1)
- spatial modelling (1)
- spatial navigation (1)
- spatial numerical associations (1)
- spatial risk profiling (1)
- spatially resolved photoluminescence (1)
- specialization (1)
- species richness (1)
- specificity (1)
- spectrometry-based proteomics (1)
- spectroscopy (1)
- spectrum (1)
- speech anxiety (1)
- speed skaters (1)
- speller performance (1)
- sperm head formation (1)
- spermatogenesis (1)
- spermine (1)
- spermiogenesis (1)
- spider phobia (1)
- spillover (1)
- spin chemistry (1)
- spin structures (1)
- spin-orbit coupling (1)
- spinal cord (1)
- spinal-cord (1)
- spinco ultracentrifuge (1)
- spire (1)
- splicing inhibition (1)
- spondyloenchondrodysplasia (1)
- sponges (1)
- spontaneously hypertensive rat (1)
- spores (1)
- spot size (1)
- squaraine polymer (1)
- stage III (1)
- standard (1)
- standard model (1)
- standing wave formation (1)
- staphylococcus aureus (1)
- statistical disperison (1)
- statistics (1)
- steady-state visually evoked potentials (1)
- steered molecular dynamics (1)
- stem cells (1)
- stem-cells (1)
- stem/progenitor cells (1)
- stenosis (1)
- steps (1)
- stimuli (1)
- stimulus (1)
- strains (1)
- strategy (1)
- street labeling (1)
- strength (1)
- streptococci (1)
- streptococcus pneumoniae (1)
- streptomyces (1)
- streptozotocin (1)
- stress (1)
- striga (1)
- stroke, acute (1)
- stroke-associated pneumonia (1)
- stromal cells (1)
- stroop interference (1)
- structural basis (1)
- structural genome variations (1)
- structural model (1)
- structured illumination (1)
- sub-saharan africa (1)
- subcutaneous injection (1)
- subsequent memory (1)
- substratal idiothetic navigation (1)
- substrate quality (1)
- substrate recognition (1)
- subthreshold IKK activation (1)
- subtilis genome (1)
- subtypes (1)
- sucrose (1)
- suicide attempt (1)
- superconductivity (1)
- superfluid (1)
- supergauge transformations (1)
- supersymmetry (1)
- surface (1)
- surface states (1)
- surface water (1)
- surfactants (1)
- surgical outcomes (1)
- surgical treatment (1)
- surprise (1)
- susceptibility loci (1)
- sustainable intensification (1)
- suture (1)
- swordtails (1)
- symbiosis (1)
- synapse (1)
- synaptic delay (1)
- synaptic transmission (1)
- synaptotagmin (1)
- synergistic reinforcement (1)
- syphilis (1)
- system bcg (1)
- systematic review (1)
- systemic candidiasis (1)
- systemic lupus erythematosus (1)
- systemic risk (1)
- systems (1)
- t-Test (1)
- tag based (1)
- tag fusion proteins (1)
- tapers (1)
- target (1)
- targets (1)
- taste receptor cells (1)
- tau leptons (1)
- taxonomy (1)
- teaching hospital (1)
- team sports (1)
- team-training (1)
- tegument protein pUL36 (1)
- telemedicine (1)
- teleostei (1)
- telluride (1)
- temporal bone (1)
- tendon (1)
- tenofovir disaproxil fumarate (1)
- term follow-up (1)
- theatre (1)
- theoretical chemistry (1)
- theory of event coding (1)
- therapeutic target (1)
- thermal gating (1)
- thermal treatment (1)
- thermodynamics (1)
- thermoelectrics (1)
- thermopower (1)
- thin film (1)
- thin-film transistors (1)
- think‐aloud data (1)
- threat learning (1)
- threat-related stimuli (1)
- three terminal device (1)
- threshold training (1)
- thrombin (1)
- thrombocytopenia (1)
- thromboembolic clot model (1)
- thromboembolic stroke (1)
- thromboinflammation (1)
- thrombolysis (1)
- thymyl cinnamate (1)
- thyroid cancer (1)
- time inhomogeneities (1)
- time trends (1)
- time-series (1)
- tolbutamide substrate (1)
- tolerance (1)
- toll-like receptor (1)
- toll-like receptor 2 (1)
- tomato (1)
- tomography (1)
- tonicity (1)
- tool (1)
- top quark (1)
- top quark mass (1)
- top quarks (1)
- top-down control (1)
- top-quark (1)
- top-quark mass (1)
- topical treatment (1)
- topographic aspect (1)
- topological (1)
- topologische Isolatoren (1)
- total energy calculations (1)
- toxicity testing (1)
- toxin (1)
- trabeculectomy (1)
- trafficking (1)
- transaction utility (1)
- transcapillary pressure gradient (1)
- transcription start site (1)
- transcriptional landscape (1)
- transcriptional regulation (1)
- transcriptional responses (1)
- transfer (1)
- transfer dynamics (1)
- transformation (1)
- transforming growth factor-beta-1 (1)
- transgenic mice (1)
- transgenic rats (1)
- transient ischemic attack (1)
- transition (1)
- translation (1)
- translation initiation (1)
- translational regulation (1)
- translational stroke research (1)
- translocation (1)
- transmission (1)
- transmission electron microscopy (1)
- transplant (1)
- transplantation states genes (1)
- transport (1)
- transport experiments (1)
- transport microenvironments (1)
- transport studies (1)
- transposable elements (1)
- transposition (1)
- transverse energy–energy correlation function (1)
- transverse relaxation (1)
- trap (1)
- treadmill protocol (1)
- treadmill running (1)
- treatment response (1)
- treatment-resistant depression (1)
- tree shrew (1)
- trees (1)
- triceps (1)
- tricuspid pressure gradient (1)
- triplosufficiency (1)
- trophic interactions (1)
- tsetse fly (1)
- tuberculosis (1)
- tuft cells (1)
- tumor biomarker (1)
- tumor cells (1)
- tumor microenvironment (1)
- tumor vascularization (1)
- tumorigenic properties (1)
- tunneling spectroscopy (1)
- turbulence (1)
- turnover (1)
- two-component systems (1)
- type 1 ICP27 (1)
- type I interferonopathy (1)
- type II GaIn(As)Sb/GaSb (1)
- type II quantum wells (1)
- type-1 (1)
- ubiquitin (1)
- ubiquitination (1)
- ulfobutylether-\(\beta\)-cyclodextrin (1)
- ultracold (1)
- ultrasonic autonomous aerial vehicles (1)
- ultraviolet-a (1)
- uncanny valley hypothesis (1)
- unconscious processing (1)
- unconventional superconductivity (1)
- undamaged DNA (1)
- understaffed (1)
- up-conversion (1)
- up-regulation (1)
- upcyte hepatocytes (1)
- uracil binding (1)
- urban vegetation (1)
- urine (1)
- usability (1)
- user-centred design (1)
- user-generated content (1)
- utaneous adverse events (1)
- utility (1)
- vacancies (1)
- vaccination program (1)
- vaccines (1)
- vacuoles (1)
- valence (1)
- valtrates (1)
- variation (1)
- vascular adhesion protein-1 (1)
- vascular normalization (1)
- vascular permeability (1)
- vector-field control (1)
- vector-field shaper (1)
- velocity (1)
- verdunstungsinduzierter Selbstanordnung (1)
- vertical agreements (1)
- vertical transmission (1)
- vesicle-based barrier (1)
- vesicles (1)
- vesicular acetylcholine transporter (1)
- viability (1)
- viral replication (1)
- virtual patients (1)
- virtual reality (1)
- visfatin (1)
- visfatin levels (1)
- vision (1)
- visualization (1)
- vitamin K antagonists (1)
- volcanic eruption (1)
- volcano (1)
- volume regulation (1)
- voluntary movement (1)
- von Willebrand factor (1)
- vulnerability (1)
- warfarin (1)
- warfarin polymorphisms (1)
- wave basis set (1)
- wave functions (1)
- wave superconductors (1)
- weak ferromagnetism (1)
- web server (1)
- weed dodder (1)
- wheat-varieties (1)
- white (1)
- white matter (1)
- whole blood specimens (1)
- whole body MRI (1)
- whole body vibration (1)
- whole-body (1)
- whole-body vibration (1)
- wildlife consumption (1)
- women (1)
- world championships (1)
- wrath (1)
- x-ray emission (1)
- xanthomonas maltophilia (1)
- yeast telomerase (1)
- zoledonic acid (1)
- zoonotic (1)
- Überwachungstechnik (1)
- Übung (1)
- β1 integrin (1)
- √s=8 TeV (1)
Institute
- Theodor-Boveri-Institut für Biowissenschaften (87)
- Physikalisches Institut (70)
- Graduate School of Life Sciences (32)
- Institut für Psychologie (31)
- Neurologische Klinik und Poliklinik (27)
- Medizinische Klinik und Poliklinik I (24)
- Medizinische Klinik und Poliklinik II (20)
- Institut für Molekulare Infektionsbiologie (19)
- Institut für Pharmazie und Lebensmittelchemie (17)
- Institut für Theoretische Physik und Astrophysik (16)
Sonstige beteiligte Institutionen
- ATLAS Collaboration (1)
- Adam Opel AG (1)
- Brown University (1)
- CERN (1)
- Center for Nanosystems Chemistry (CNC), Universität Würzburg, Am Hubland, 97074 Würzburg, Germany (1)
- Deutscher Akademischer Austauschdienst (DAAD) (1)
- Deutsches Zentrum für Luft- und Raumfahrt (DLR), Institut für Raumfahrtsysteme (1)
- Institut für Hygiene und Mikrobiologie (1)
- Instituto de Higiene, Universidad de la República, Montevideo, Uruguay (1)
- König-Ludwig-Haus, Orthopedic Clinic, Würzburg (1)
ResearcherID
- B-1911-2015 (1)
- C-2593-2016 (1)
- D-1221-2009 (1)
- N-2030-2015 (1)
- N-3741-2015 (1)
Phenotypic heterogeneity at the cellular level in response to various stresses, e.g., antibiotic treatment has been reported for a number of bacteria. In a clonal population, cell-to-cell variation may result in phenotypic heterogeneity that is a mechanism to survive changing environments including antibiotic therapy. Stenotrophomonas rnaltophilia has been frequently isolated from cystic fibrosis patients, can cause numerous infections in other organs and tissues, and is difficult to treat due to antibiotic resistances. S. maltophilia K279a produces the Li and L2 beta-lactamases in response to beta-lactam treatment. Here we report that the patient isolate S. rnaltophilia K279a diverges into cellular subpopulations with distinct but reversible morphotypes of small and big colonies when challenged with ampicillin. This observation is consistent with the formation of elongated chains of bacteria during exponential growth phase and the occurrence of mainly rod-shaped cells in liquid media. RNA-seq analysis of small versus big colonies revealed differential regulation of at least seven genes among the colony morphotypes. Among those, bleu and bla(L2) were transcriptionally the most strongly upregulated genes. Promoter fusions of b/a(L1) and b/a(L2) genes indicated that expression of both genes is also subject to high levels of phenotypic heterogeneous expression on a single cell level. Additionally, the comE homolog was found to be differentially expressed in homogenously versus heterogeneously bla(L2) expressing cells as identified by RNA(seq) analysis. Overexpression of cornE in S. maltophilia K279a reduced the level of cells that were in a bla(L2)-ON mode to 1% or lower. Taken together, our data provide strong evidence that S. maltophilia K279a populations develop phenotypic heterogeneity in an ampicillin challenged model. This cellular variability is triggered by regulation networks including b/a(L1), b/a(L2), and comE.
Virotherapy on the basis of oncolytic vaccinia virus (VACV) strains is a novel approach for canine cancer therapy. Here we describe, for the first time, the characterization and the use of VACV strain GLV-5b451 expressing the anti-vascular endothelial growth factor (VEGF) single-chain antibody (scAb) GLAF-2 as therapeutic agent against different canine cancers. Cell culture data demonstrated that GLV-5b451 efficiently infected and destroyed all four tested canine cancer cell lines including: mammary carcinoma (MTH52c), mammary adenoma (ZMTH3), prostate carcinoma (CT1258), and soft tissue sarcoma (STSA-1). The GLV-5b451 virus-mediated production of GLAF-2 antibody was observed in all four cancer cell lines. In addition, this antibody specifically recognized canine VEGF. Finally, in canine soft tissue sarcoma (CSTS) xenografted mice, a single systemic administration of GLV-5b451 was found to be safe and led to anti-tumor effects resulting in the significant reduction and substantial long-term inhibition of tumor growth. A CD31-based immuno-staining showed significantly decreased neo-angiogenesis in GLV-5b451-treated tumors compared to the controls. In summary, these findings indicate that GLV-5b451 has potential for use as a therapeutic agent in the treatment of CSTS.
Background
The dmrt1 and sox9 genes have a well conserved function related to testis formation in vertebrates, and the group of fish presents a great diversity of species and reproductive mechanisms. The lambari fish (Astyanax altiparanae) is an important Neotropical species, where studies on molecular level of sex determination and gonad maturation are scarce.
Methods
Here, we employed molecular cloning techniques to analyze the cDNA sequences of the dmrt1 and sox9 genes, and describe the expression pattern of those genes during development and the male reproductive cycle by qRT-PCR, and related to histology of the gonad.
Results
Phylogenetic analyses of predicted amino acid sequences of dmrt1 and sox9 clustered A. altiparanae in the Ostariophysi group, which is consistent with the morphological phylogeny of this species. Studies of the gonad development revealed that ovary formation occurred at 58 days after hatching (dah), 2 weeks earlier than testis formation. Expression studies of sox9 and dmrt1 in different tissues of adult males and females and during development revealed specific expression in the testis, indicating that both genes also have a male-specific role in the adult. During the period of gonad sex differentiation, dmrt1 seems to have a more significant role than sox9. During the male reproductive cycle dmrt1 and sox9 are down-regulated after spermiation, indicating a role of these genes in spermatogenesis.
Conclusions
For the first time the dmrt1 and sox9 were cloned in a Characiformes species. We show that both genes have a conserved structure and expression, evidencing their role in sex determination, sex differentiation and the male reproductive cycle in A. altiparanae. These findings contribute to a better understanding of the molecular mechanisms of sex determination and differentiation in fish.
Background:
The interaction of eukaryotic host and prokaryotic pathogen cells is linked to specific changes in the cellular proteome, and consequently to infection-related gene expression patterns of the involved cells. To simultaneously assess the transcriptomes of both organisms during their interaction we developed dual 3'Seq, a tag-based sequencing protocol that allows for exact quantification of differentially expressed transcripts in interacting pro-and eukaryotic cells without prior fixation or physical disruption of the interaction.
Results:
Human epithelial cells were infected with Salmonella enterica Typhimurium as a model system for invasion of the intestinal epithelium, and the transcriptional response of the infected host cells together with the differential expression of invading and intracellular pathogen cells was determined by dual 3'Seq coupled with the next-generation sequencing-based transcriptome profiling technique deepSuperSAGE (deep Serial Analysis of Gene Expression). Annotation to reference transcriptomes comprising the operon structure of the employed S. enterica Typhimurium strain allowed for in silico separation of the interacting cells including quantification of polycistronic RNAs. Eighty-nine percent of the known loci are found to be transcribed in prokaryotic cells prior or subsequent to infection of the host, while 75% of all protein-coding loci are represented in the polyadenylated transcriptomes of human host cells.
Conclusions:
Dual 3'Seq was alternatively coupled to MACE (Massive Analysis of cDNA ends) to assess the advantages and drawbacks of a library preparation procedure that allows for sequencing of longer fragments. Additionally, the identified expression patterns of both organisms were validated by qRT-PCR using three independent biological replicates, which confirmed that RELB along with NFKB1 and NFKB2 are involved in the initial immune response of epithelial cells after infection with S. enterica Typhimurium.
The Urban Heat Island (UHI) is the phenomenon of altered increased temperatures in urban areas compared to their rural surroundings. UHIs grow and intensify under extreme hot periods, such as during heat waves, which can affect human health and also increase the demand for energy for cooling. This study applies remote sensing and land use/land cover (LULC) data to assess the cooling effect of varying urban vegetation cover, especially during extreme warm periods, in the city of Munich, Germany. To compute the relationship between Land Surface Temperature (LST) and Land Use Land Cover (LULC), MODIS eight-day interval LST data for the months of June, July and August from 2002 to 2012 and the Corine Land Cover (CLC) database were used. Due to similarities in the behavior of surface temperature of different CLCs, some classes were reclassified and combined to form two major, rather simplified, homogenized classes: one of built-up area and one of urban vegetation. The homogenized map was merged with the MODIS eight-day interval LST data to compute the relationship between them. The results revealed that (i) the cooling effect accrued from urban vegetation tended to be non-linear; and (ii) a remarkable and stronger cooling effect in terms of LST was identified in regions where the proportion of vegetation cover was between seventy and almost eighty percent per square kilometer. The results also demonstrated that LST within urban vegetation was affected by the temperature of the surrounding built-up and that during the well-known European 2003 heat wave, suburb areas were cooler from the core of the urbanized region. This study concluded that the optimum green space for obtaining the lowest temperature is a non-linear trend. This could support urban planning strategies to facilitate appropriate applications to mitigate heat-stress in urban area.
A simple test setup has been developed at Institute of Aerospace Information Technology, University of Würzburg, Germany to realize basic functionalities for formation flight of quadrocopters. The test environment is planned to be utilized for developing and validating the algorithms for formation flying capability in real environment as well as for education purpose. An already existing test bed for single quadrocopter was extended with necessary inter-communication and distributed control mechanism to test the algorithms for formation flights in 2 degrees of freedom (roll / pitch). This study encompasses the domain of communication, control engineering and embedded systems programming. Bluetooth protocol has been used for inter-communication between two quadrocopters. A simple approach of PID control in combination with Kalman filter has been exploited. MATLAB Instrument Control Toolbox has been used for data display, plotting and analysis. Plots can be drawn in real-time and received information can also be stored in the form of files for later use and analysis. The test setup has been developed indigenously and at considerably low cost. Emphasis has been placed on simplicity to facilitate students learning process. Several lessons have been learnt during the course of development of this setup. Proposed setup is quite flexible that can be modified as per changing requirements.
The flagellate Trypanosoma brucei, which causes the sleeping sickness when infecting a mammalian host, goes through an intricate life cycle. It has a rather complex propulsion mechanism and swims in diverse microenvironments. These continuously exert selective pressure, to which the trypanosome adjusts with its architecture and behavior. As a result, the trypanosome assumes a diversity of complex morphotypes during its life cycle. However, although cell biology has detailed form and function of most of them, experimental data on the dynamic behavior and development of most morphotypes is lacking. Here we show that simulation science can predict intermediate cell designs by conducting specific and controlled modifications of an accurate, nature-inspired cell model, which we developed using information from live cell analyses. The cell models account for several important characteristics of the real trypanosomal morphotypes, such as the geometry and elastic properties of the cell body, and their swimming mechanism using an eukaryotic flagellum. We introduce an elastic network model for the cell body, including bending rigidity and simulate swimming in a fluid environment, using the mesoscale simulation technique called multi-particle collision dynamics. The in silico trypanosome of the bloodstream form displays the characteristic in vivo rotational and translational motility pattern that is crucial for survival and virulence in the vertebrate host. Moreover, our model accurately simulates the trypanosome's tumbling and backward motion. We show that the distinctive course of the attached flagellum around the cell body is one important aspect to produce the observed swimming behavior in a viscous fluid, and also required to reach the maximal swimming velocity. Changing details of the flagellar attachment generates less efficient swimmers. We also simulate different morphotypes that occur during the parasite's development in the tsetse fly, and predict a flagellar course we have not been able to measure in experiments so far.
In the present thesis the MBE growth and sample characterization of HgTe structures is investigated
and discussed. Due to the first experimental discovery of the quantum Spin Hall effect
(QSHE) in HgTe quantum wells, this material system attains a huge interest in the spintronics
society. Because of the long history of growing Hg-based heterostructures here at the Experimentelle
Physik III in Würzburg, there are very good requirements to analyze this material
system more precisely and in new directions. Since in former days only doped HgTe quantum
wells were grown, this thesis deals with the MBE growth in the (001) direction of undoped
HgTe quantum wells, surface located quantum wells and three dimensional bulk layers. All
Hg-based layers were grown on CdTe substrates which generate strain in the layer stack and
provide therefore new physical effects. In the same time, the (001) CdTe growth was investigated
on n-doped (001) GaAs:Si because the Japanese supplier of CdTe substrates had a
supply bottleneck due to the Tohoku earthquake and its aftermath in 2011.
After a short introduction of the material system, the experimental techniques were demonstrated
and explained explicitly. After that, the experimental part of this thesis is displayed.
So, the investigation of the (001) CdTe growth on (001) GaAs:Si is discussed in chapter 4.
Firstly, the surface preparation of GaAs:Si by oxide desorption is explored and analyzed.
Here, rapid thermal desorption of the GaAs oxide with following cool down in Zn atmosphere
provides the best results for the CdTe due to small holes at the surface, while e.g. an atomic
flat GaAs buffer deteriorates the CdTe growth quality. The following ZnTe layer supplies the
(001) growth direction of the CdTe and exhibits best end results of the CdTe for 30 seconds
growth time at a flux ratio of Zn/Te ~ 1/1.2. Without this ZnTe layer, CdTe will grow in the
(111) direction. However, the main investigation is here the optimization of the MBE growth
of CdTe. The substrate temperature, Cd/Te flux ratio and the growth time has to be adjusted
systematically. Therefore, a complex growth process is developed and established. This optimized
CdTe growth process results in a RMS roughness of around 2.5 nm and a FWHM value
of the HRXRD w-scan of 150 arcsec. Compared to the literature, there is no lower FWHM
value traceable for this growth direction. Furthermore, etch pit density measurements show
that the surface crystallinity is matchable with the commercial CdTe substrates (around 1x10^4
cm^(-2)). However, this whole process is not completely perfect and offers still room for improvements.
The growth of undoped HgTe quantum wells was also a new direction in research in contrast
to the previous n-doped grown HgTe quantum wells. Here in chapter 5, the goal of very low
carrier densities was achieved and therefore it is now possible to do transport experiments in
the n - and p - region by tuning the gate voltage. To achieve this high sample quality, very precise
growth of symmetric HgTe QWs and their HRXRD characterization is examined. Here,
the quantum well thickness can now determined accurate to under 0.3 nm. Furthermore, the transport analysis of different quantum well thicknesses shows that the carrier density and
mobility increase with rising HgTe layer thickness. However, it is found out that the band
gap of the HgTe QW closes indirectly at a thickness of 11.6 nm. This is caused by the tensile
strained growth on CdTe substrates. Moreover, surface quantum wells are studied. These
quantum wells exhibit no or a very thin HgCdTe cap. Though, oxidization and contamination
of the surface reduces here the carrier mobility immensely and a HgCdTe layer of around 5 nm
provides the pleasing results for transport experiments with superconductors connected to the
topological insulator [119]. A completely new achievement is the realization of MBE growth
of HgTe quantum wells on CdTe/GaAs:Si substrates. This is attended by the optimization of
the CdTe growth on GaAs:Si. It exposes that HgTe quantum wells grown in-situ on optimized
CdTe/GaAs:Si show very nice transport data with clear Hall plateaus, SdH oscillations, low
carrier densities and carrier mobilities up to 500 000 cm^2/Vs. Furthermore, a new oxide etching
process is developed and analyzed which should serve as an alternative to the standard
HCl process which generates volcano defects at some time. However, during the testing time
the result does not differ in Nomarski, HRXRD, AFM and transport measurements. Here,
long-time tests or etching and mounting in nitrogen atmosphere may provide new elaborate
results.
The main focus of this thesis is on the MBE growth and standard characterization of HgTe bulk
layers and is discussed in chapter 6. Due to the tensile strained growth on lattice mismatched
CdTe, HgTe bulk opens up a band gap of around 22 meV at the G-point and exhibits therefore
its topological surface states. The analysis of surface condition, roughness, crystalline quality,
carrier density and mobility via Nomarski, AFM, XPS, HRXRD and transport measurements
is therefore included in this work. Layer thickness dependence of carrier density and mobility
is identified for bulk layer grown directly on CdTe substrates. So, there is no clear correlation
visible between HgTe layer thickness and carrier density or mobility. So, the carrier density is
almost constant around 1x10^11 cm^(-2) at 0 V gate voltage. The carrier mobility of these bulk
samples however scatters between 5 000 and 60 000 cm^2/Vs almost randomly. Further experiments
should be made for a clearer understanding and therefore the avoidance of unusable
bad samples.But, other topological insulator materials show much higher carrier densities and
lower mobility values. For example, Bi2Se3 exhibits just density values around 1019 cm^(-2)
and mobility values clearly below 5000 cm2/Vs. The carrier density however depends much
on lithography and surface treatment after growth. Furthermore, the relaxation behavior and
critical thickness of HgTe grown on CdTe is determined and is in very good agreement with
theoretical prediction (d_c = 155 nm). The embedding of the HgTe bulk layer between HgCdTe
layers created a further huge improvement. Similar to the quantum well structures the carrier
mobility increases immensely while the carrier density levels at around 1x10^11 cm^(-2) at 0
V gate voltage as well. Additionally, the relaxation behavior and critical thickness of these
barrier layers has to be determined. HgCdTe grown on commercial CdTe shows a behavior as
predicted except the critical thickness which is slightly higher than expected (d_c = 850 nm).
Otherwise, the relaxation of HgCdTe grown on CdTe/GaAs:Si occurs in two parts. The layer
is fully strained up to 250 nm. Between 250 nm and 725 nm the HgCdTe film starts to relax
randomly up to 10 %. The relaxation behavior for thicknesses larger than 725 nm occurs than
linearly to the inverse layer thickness. A explanation is given due to rough interface conditions
and crystalline defects of the CdTe/GaAs:Si compared to the commercial CdTe substrate. HRXRD and AFM data support this statement. Another point is that the HgCdTe barriers protect the active HgTe layer and because of the high carrier mobilities the Hall measurements provide new transport data which have to be interpreted more in detail in the future. In addition, HgTe bulk samples show very interesting transport data by gating the sample from the top and the back. It is now possible to manipulate the carrier densities of the top and bottom surface states almost separately. The back gate consisting of the n-doped GaAs substrate and the thick insulating CdTe buffer can tune the carrier density for Delta(n) ~ 3x10^11 cm^(-2). This is sufficient to tune the Fermi energy from the p-type into the n-type region [138].
In this thesis it is shown that strained HgTe bulk layers exhibit superior transport data by embedding between HgCdTe barrier layers. The n-doped GaAs can here serve as a back gate.
Furthermore, MBE growth of high crystalline, undoped HgTe quantum wells shows also new
and extended transport output. Finally, it is notable that due to the investigated CdTe growth
on GaAs the Hg-based heterostructure MBE growth is partially independent from commercial
suppliers.
The brain-derived neurotrophic factor BDNF plays a critical role in neuronal development and the induction of L-LTP at glutamatergic synapses in several brain regions. However, the cellular and molecular mechanisms underlying these BDNF effects have not been firmly established. Using in vitro cultures of cortical neurons from knockout mice for Pld1 and Rsk2, BDNF was observed to induce a rapid RSK2-dependent activation of PLD and to stimulate BDNF ERK1/2-CREB and mTor-S6K signalling pathways, but these effects were greatly reduced in Pld1\(^{-/-}\) neurons. Furthermore, phospho-CREB did not accumulate in the nucleus, whereas overexpression of PLD1 amplified the BDNF-dependent nuclear recruitment of phospho-ERK1/2 and phospho-CREB. This BDNF retrograde signalling was prevented in cells silenced for the scaffolding protein PEA15, a protein which complexes with PLD1, ERK1/2, and RSK2 after BDNF treatment. Finally PLD1, ERK1/2, and RSK2 partially colocalized on endosomal structures, suggesting that these proteins are part of the molecular module responsible for BDNF signalling in cortical neurons.
Background
International collaborative research is a mechanism for improving the development of disease-specific therapies and for improving health at the population level. However, limited data are available to assess the trends in research output related to orphan diseases.
Methods and Findings
We used bibliometric mapping and clustering methods to illustrate the level of fragmentation in myeloma research and the development of collaborative efforts. Publication data from Thomson Reuters Web of Science were retrieved for 2005-2009 and followed until 2013. We created a database of multiple myeloma publications, and we analysed impact and co-authorship density to identify scientific collaborations, developments, and international key players over time. The global annual publication volume for studies on multiple myeloma increased from 1,144 in 2005 to 1,628 in 2009, which represents a 43% increase. This increase is high compared to the 24% and 14% increases observed for lymphoma and leukaemia. The major proportion (> 90% of publications) was from the US and EU over the study period. The output and impact in terms of citations, identified several successful groups with a large number of intra-cluster collaborations in the US and EU. The US-based myeloma clusters clearly stand out as the most productive and highly cited, and the European Myeloma Network members exhibited a doubling of collaborative publications from 2005 to 2009, still increasing up to 2013.
Conclusion and Perspective
Multiple myeloma research output has increased substantially in the past decade. The fragmented European myeloma research activities based on national or regional groups are progressing, but they require a broad range of targeted research investments to improve multiple myeloma health care.
In classical conditioning, an initially neutral stimulus (conditioned stimulus, CS) becomes associated with a biologically salient event (unconditioned stimulus, US), which might be pain (aversive conditioning) or food (appetitive conditioning). After a few associations, the CS is able to initiate either defensive or consummatory responses, respectively. Contrary to aversive conditioning, appetitive conditioning is rarely investigated in humans, although its importance for normal and pathological behaviors (e.g., obesity, addiction) is undeniable. The present study intents to translate animal findings on appetitive conditioning to humans using food as an US. Thirty-three participants were investigated between 8 and 10 am without breakfast in order to assure that they felt hungry. During two acquisition phases, one geometrical shape (avCS+) predicted an aversive US (painful electric shock), another shape (appCS+) predicted an appetitive US (chocolate or salty pretzel according to the participants' preference), and a third shape (CS) predicted neither US. In a extinction phase, these three shapes plus a novel shape (NEW) were presented again without US delivery. Valence and arousal ratings as well as startle and skin conductance (SCR) responses were collected as learning indices. We found successful aversive and appetitive conditioning. On the one hand, the avCS+ was rated as more negative and more arousing than the CS and induced startle potentiation and enhanced SCR. On the other hand, the appCS+ was rated more positive than the CS and induced startle attenuation and larger SCR. In summary, we successfully confirmed animal findings in (hungry) humans by demonstrating appetitive learning and normal aversive learning.
Swelling-activated pathways for myo-inositol, one of the most abundant organic osmolytes in mammalian cells, have not yet been identified. The present study explores the SLC5A3 protein as a possible transporter of myo-inositol in hyponically swollen HEK293 cells. To address this issue, we examined the relationship between the hypotonicity-induced changes in plasma membrane permeability to myo-inositol Pino [m/s] and expression/localization of SLC5A3. Pino values were determined by cell volumetry over a wide tonicity range (100–275 mOsm) in myo-inositol-substituted solutions. While being negligible under mild hypotonicity (200–275 mOsm), Pino grew rapidly at osmolalities below 200 mOsm to reach a maximum of ∼3 nm/s at 100–125 mOsm, as indicated by fast cell swelling due to myo-inositol influx. The increase in Pino resulted most likely from the hypotonicity-mediated incorporation of cytosolic SLC5A3 into the plasma membrane, as revealed by confocal fluorescence microscopy of cells expressing EGFP-tagged SLC5A3 and super-resolution imaging of immunostained SLC5A3 by direct stochastic optical reconstruction microscopy (dSTORM). dSTORM in hypotonic cells revealed a surface density of membrane-associated SLC5A3 proteins of 200–2000 localizations/μm2. Assuming SLC5A3 to be the major path for myo-inositol, a turnover rate of 80–800 myo-inositol molecules per second for a single transporter protein was estimated from combined volumetric and dSTORM data. Hypotonic stress also caused a significant upregulation of SLC5A3 gene expression as detected by semiquantitative RT-PCR and Western blot analysis. In summary, our data provide first evidence for swelling-mediated activation of SLC5A3 thus suggesting a functional role of this transporter in hypotonic volume regulation of mammalian cells.
LIM and SH3 protein 1 (LASP1) is a nucleocytoplasmic scaffolding protein. LASP1 interacts with various cytoskeletal proteins via its domain structure and is known to participate in physiological processes of cells. In the present study, a detailed investigation of the expression pattern of LASP1 protein in normal skin, melanocytic nevi and melanoma was carried out and the melanocyte–specific function of LASP1 was analyzed. LASP1 protein was identified in stratum basale of skin epidermis and a very high level was detected in nevi, the benign tumor of melanocyte. In the highly proliferative basal cells, an additional distinct nuclear localization of the protein was noted. In different tumor entities, an elevated LASP1 expression and nuclear localization, correlated positively with malignancy and tumor grade. However, LASP1 level was determined to be very low in melanoma and even reduced in metastases. Melanoma is distinguished as the first tumor tested to date – that displayed an absence of elevated LASP1 expression. In addition no significant relation was observed between LASP1 protein expression and clinicopathological parameters in melanoma.
The epidermal melanin unit of skin comprises of melanocytes and keratinocytes. Melanocytes are specialized cells that synthesize the photo protective coloring pigment, melanin inside unique organelles called melanosomes. The presence of LASP1 in melanocytes is reported for the first time through this study and the existence was confirmed by immunoblotting analysis in cultured normal human epidermal melanocyte (NHEM) and in melanoma cell lines, along with the immunohistostaining imaging in normal skin and in melanocytic nevi. LASP1 depletion in MaMel2 cells revealed a moderate increase in the intracellular melanin level independently of de novo melanogenesis, pointing to a partial hindrance in melanin release. Immunofluorescence images of NHEM and MaMel2 cells visualized co-localization of LASP1 with dynamin and tyrosinase concomitant with melanosomes at the dendrite tips of the cells. Melanosome isolation experiments by sucrose density gradient centrifugation clearly demonstrated the presence of LASP1 and the melanosome specific markers tyrosinase and TRP1 in late stage melanosomes.
The study identified LASP1 and dynamin as novel binding partners in melanocytes and provides first evidence for the existence of LASP1 and dynamin (a protein well–known for its involvement in vesicle formation and budding) in melanosomes. Co-localization of LASP1 and dynamin along the dendrites and at the tips of the melanocytes indicates a potential participation of the two proteins in the membrane vesicle fission at the plasma membrane.
In summary, a possible involvement of LASP1 in the actin–dynamin mediated membrane fission and exocytosis of melanin laden melanosome vesicles into the extracellular matrix is suggested.
Part 1 of this work describes the development of accurate physically grounded force fields for
intermolecular Cation-π interactions based on SAPT energy decomposition analysis.
The presented results demonstrate the benefits of the used DFT-SAPT method to describe non-bonding
interactions. First of all, this method is able to reproduce the high level CCSD(T) energy values
but using much less computational time. Second it provides the possibility to separate the total
intermolecular interaction energy into several physically meaningful contributions. The relative
contributions of the dimers investigated can be seen in Fig. 6.16. In Tab. 6.3 the percentage
contribution of the attractive energy parts to the stabilization energy is shown. The polarization
energy is important for the NH+...C6H6 interaction, whereas it becomes less crucial
considering other dimers. The dispersion energy contribution is large in the case of
the C6H6...H2O dimers, whereas it is relatively less important for the NH+...C6H6
interaction. The electrostatic energy contributes a large amount of stabilizing energy
in all considered dimer interactions. ...
Electric shock is a common stimulus for nociception-research and the most widely used reinforcement in aversive associative learning experiments. Yet, nothing is known about the mechanisms it recruits at the periphery. To help fill this gap, we undertook a genome-wide association analysis using 38 inbred Drosophila melanogaster strains, which avoided shock to varying extents. We identified 514 genes whose expression levels and/or sequences covaried with shock avoidance scores. We independently scrutinized 14 of these genes using mutants, validating the effect of 7 of them on shock avoidance. This emphasizes the value of our candidate gene list as a guide for follow-up research. In addition, by integrating our association results with external protein-protein interaction data we obtained a shock avoidance- associated network of 38 genes. Both this network and the original candidate list contained a substantial number of genes that affect mechanosensory bristles, which are hairlike organs distributed across the fly's body. These results may point to a potential role for mechanosensory bristles in shock sensation. Thus, we not only provide a first list of candidate genes for shock avoidance, but also point to an interesting new hypothesis on nociceptive mechanisms.
Background
To use combinatorial epitope mapping ("fingerprinting") of the antibody response to identify targets of the humoral immune response in patients with transitional cell carcinoma (TCC) of the bladder.
Methods
A combinatorial random peptide library was screened on the circulating pool of immunoglobulins purified from an index patient with a high risk TCC (pTa high grade plus carcinoma in situ) to identify corresponding target antigens. A patient cohort was investigated for antibody titers against ubiquitin.
Results
We selected, isolated, and validated an immunogenic peptide motif from ubiquitin as a dominant epitope of the humoral response. Patients with TCC had significantly higher antibody titers against ubiquitin than healthy donors (p<0.007), prostate cancer patients (p<0.0007), and all patients without TCC taken together (p<0.0001). Titers from superficial tumors were not significantly different from muscle invasive tumors (p = 0.0929). For antibody response against ubiquitin, sensitivity for detection of TCC was 0.44, specificity 0.96, positive predictive value 0.96 and negative predictive value 0.41. No significant titer changes were observed during the standard BCG induction immunotherapy.
Conclusions
This is the first report to demonstrate an anti-ubiquitin antibody response in patients with TCC. Although sensitivity of antibody production was low, a high specificity and positive predictive value make ubiquitin an interesting candidate for further diagnostic and possibly immune modulating studies.
Merocyanine Dyes as Organic Semiconductors for Vacuum-processed Solar Cell and Transistor Devices
(2015)
The present thesis comprises the synthesis of new functional merocyanine dyes, the study of their electro-optical properties as well as solid state packing and their application as p-type semiconductor materials in transistor and solar cell devices. The absorption properties of the obtained compounds could be modified by variation of the donor unit, the introduction of electron-withdrawing substituents in the acceptor unit or elongation of the polymethine chain. For a particular dye, the absorption band could be shifted by more than 160 nm by increasing the solvent polarity due to a conformational switch between a merocyanine-like and a cyanine-like structure. Single crystal analyses revealed that the studied dyes tend to pack either in an antiparallel fashion forming dimers with no overall dipole moment or in a staircase-like pattern where the dipole moments point to the same direction and are only balanced by another staircase oriented in the opposite direction (stair dimer). With respect to application as semiconductor materials, the latter packing arrangement resulted most favorable for charge carrier mobility. We concluded that this packing motif is preserved in the solar cell devices, where the selenium-containing dye afforded the highest performance of this series for an optimized planar-mixed heterojunction solar cell (6.2 %).
Robust risk assessment requires accurate flood intensity area mapping to allow for the identification of populations and elements at risk. However, available flood maps in West Africa lack spatial variability while global datasets have resolutions too coarse to be relevant for local scale risk assessment. Consequently, local disaster managers are forced to use traditional methods such as watermarks on buildings and media reports to identify flood hazard areas. In this study, remote sensing and Geographic Information System (GIS) techniques were combined with hydrological and statistical models to delineate the spatial limits of flood hazard zones in selected communities in Ghana, Burkina Faso and Benin. The approach involves estimating peak runoff concentrations at different elevations and then applying statistical methods to develop a Flood Hazard Index (FHI). Results show that about half of the study areas fall into high intensity flood zones. Empirical validation using statistical confusion matrix and the principles of Participatory GIS show that flood hazard areas could be mapped at an accuracy ranging from 77% to 81%. This was supported with local expert knowledge which accurately classified 79% of communities deemed to be highly susceptible to flood hazard. The results will assist disaster managers to reduce the risk to flood disasters at the community level where risk outcomes are first materialized.
Ligand-binding of Cys-loop receptors is determined by N-terminal extracellular loop structures from the plus as well as from the minus side of two adjacent subunits in the pentameric receptor complex. An aromatic residue in loop B of the glycine receptor (GIyR) undergoes direct interaction with the incoming ligand via a cation-π interaction. Recently, we showed that mutated residues in loop B identified from human patients suffering from hyperekplexia disturb ligand-binding. Here, we exchanged the affected human residues by amino acids found in related members of the Cys-loop receptor family to determine the effects of side chain volume for ion channel properties. GIyR variants were characterized in vitro following transfection into cell lines in order to analyze protein expression, trafficking, degradation and ion channel function. GIyR α1 G160 mutations significantly decrease glycine potency arguing for a positional effect on neighboring aromatic residues and consequently glycine-binding within the ligand-binding pocket. Disturbed glycinergic inhibition due to T162 α1 mutations is an additive effect of affected biogenesis and structural changes within the ligand-binding site. Protein trafficking from the ER toward the ER-Golgi intermediate compartment, the secretory Golgi pathways and finally the cell surface is largely diminished, but still sufficient to deliver ion channels that are functional at least at high glycine concentrations. The majority of T162 mutant protein accumulates in the ER and is delivered to ER-associated proteasomal degradation. Hence, G160 is an important determinant during glycine binding. In contrast, 1162 affects primarily receptor biogenesis whereas exchanges in functionality are secondary effects thereof.
Extreme value theory aims at modeling extreme but rare events from a probabilistic point of view. It is well-known that so-called generalized Pareto distributions, which are briefly reviewed in Chapter 1, are the only reasonable probability distributions suited for modeling observations above a high threshold, such as waves exceeding the height of a certain dike, earthquakes having at least a certain intensity, and, after applying a simple transformation, share prices falling below some low threshold. However, there are cases for which a generalized Pareto model might fail. Therefore, Chapter 2 derives certain neighborhoods of a generalized Pareto distribution and provides several statistical tests for these neighborhoods, where the cases of observing finite dimensional data and of observing continuous functions on [0,1] are considered. By using a notation based on so-called D-norms it is shown that these tests consistently link both frameworks, the finite dimensional and the functional one. Since the derivation of the asymptotic distributions of the test statistics requires certain technical restrictions, Chapter 3 analyzes these assumptions in more detail. It provides in particular some examples of distributions that satisfy the null hypothesis and of those that do not. Since continuous copula processes are crucial tools for the functional versions of the proposed tests, it is also discussed whether those copula processes actually exist for a given set of data. Moreover, some practical advice is given how to choose the free parameters incorporated in the test statistics. Finally, a simulation study in Chapter 4 compares the in total three different test statistics with another test found in the literature that has a similar null hypothesis. This thesis ends with a short summary of the results and an outlook to further open questions.