Refine
Year of publication
Document Type
- Journal article (7493)
- Doctoral Thesis (2775)
- Book article / Book chapter (133)
- Conference Proceeding (108)
- Preprint (107)
- Working Paper (66)
- Review (43)
- Report (27)
- Master Thesis (26)
- Book (20)
Language
- English (10822) (remove)
Keywords
- Toxikologie (119)
- Medizin (99)
- inflammation (90)
- Psychologie (86)
- Biochemie (85)
- cancer (76)
- Organische Chemie (68)
- gene expression (68)
- Anorganische Chemie (66)
- Maus (64)
- Taufliege (62)
- apoptosis (59)
- Infektionsbiologie (58)
- Biologie (57)
- boron (56)
- expression (55)
- COVID-19 (53)
- Drosophila (51)
- Neurobiologie (51)
- machine learning (50)
- depression (48)
- Physiologische Chemie (47)
- virtual reality (47)
- Hadron-Hadron scattering (experiments) (45)
- breast cancer (45)
- children (45)
- multiple myeloma (44)
- therapy (42)
- Signaltransduktion (39)
- MRI (38)
- Thrombozyt (38)
- infection (38)
- melanoma (38)
- T cells (37)
- Topologischer Isolator (37)
- evolution (37)
- ischemic stroke (37)
- mice (37)
- remote sensing (37)
- Escherichia coli (36)
- anxiety (36)
- metabolism (36)
- DNA damage (35)
- Drosophila melanogaster (35)
- biomarker (35)
- cytokines (35)
- stroke (35)
- Genexpression (34)
- Krebs <Medizin> (34)
- PET (34)
- SARS-CoV-2 (34)
- Staphylococcus aureus (34)
- Virologie (34)
- oxidative stress (34)
- Immunologie (33)
- biodiversity (33)
- climate change (33)
- prostate cancer (33)
- Candida albicans (32)
- Germany (32)
- in vitro (32)
- multiple sclerosis (32)
- Tissue Engineering (31)
- brain (31)
- magnetic resonance imaging (31)
- Evolution (30)
- platelets (30)
- Apoptosis (29)
- Leistungsbewertung (29)
- T-Lymphozyt (29)
- deep learning (29)
- macrophages (29)
- phosphorylation (29)
- ADHD (28)
- fluorescence (28)
- gene (28)
- genetics (28)
- heart failure (28)
- Chirurgie (27)
- protein (27)
- B cells (26)
- Biene (26)
- HIV (26)
- Simulation (26)
- positron emission tomography (26)
- DNA (25)
- DNA methylation (25)
- Fabry disease (25)
- High energy physics (25)
- Parton Distributions (25)
- Selbstorganisation (25)
- dendritic cells (25)
- diagnosis (25)
- learning (25)
- medicine (25)
- physics (25)
- Animal Studies (24)
- China (24)
- Cultural Animal Studies (24)
- Cultural Studies (24)
- Dendritische Zelle (24)
- EEG (24)
- Ecocriticism (24)
- Environmental Humanities (24)
- Human-Animal Studies (24)
- Literary Studies (24)
- Maschinelles Lernen (24)
- Neisseria meningitidis (24)
- RNA (24)
- Trypanosoma brucei (24)
- autophagy (24)
- neuroinflammation (24)
- signal transduction (24)
- survival (24)
- tissue engineering (24)
- 3D printing (23)
- identification (23)
- immunotherapy (23)
- mortality (23)
- mouse model (23)
- Chemie (22)
- Lernen (22)
- Melanom (22)
- Molekulargenetik (22)
- Parkinson's disease (22)
- Parkinson’s disease (22)
- Positronen-Emissions-Tomografie (22)
- Supramolekulare Chemie (22)
- behavior (22)
- blood (22)
- chronic kidney disease (22)
- disease (22)
- mitochondria (22)
- mouse (22)
- obesity (22)
- stem cells (22)
- Molekularbiologie (21)
- Transkriptionsfaktor (21)
- activation (21)
- artificial intelligence (21)
- differentiation (21)
- ATLAS detector (20)
- Aspergillus fumigatus (20)
- Cancer (20)
- Fluoreszenz (20)
- Fluoreszenzmikroskopie (20)
- Genregulation (20)
- LHC (20)
- Molekularstrahlepitaxie (20)
- Schwertkärpfling (20)
- Virtuelle Realität (20)
- classification (20)
- endothelial cells (20)
- myocardial infarction (20)
- pain (20)
- perception (20)
- physical activity (20)
- prognosis (20)
- quality of life (20)
- radiotherapy (20)
- self-assembly (20)
- surgery (20)
- Bioinformatik (19)
- Kernspintomografie (19)
- Klimaänderung (19)
- Photoelektronenspektroskopie (19)
- antibodies (19)
- attention (19)
- binding (19)
- cytoskeleton (19)
- deep brain stimulation (19)
- epidemiology (19)
- immunohistochemistry (19)
- management (19)
- regulatory T cells (19)
- theranostics (19)
- toxicity (19)
- virulence (19)
- Apis mellifera (18)
- CXCR4 (18)
- Fernerkundung (18)
- Gehirn (18)
- Modellierung (18)
- Spektroskopie (18)
- aging (18)
- biology (18)
- colorectal cancer (18)
- cytotoxicity (18)
- emotion (18)
- extracellular matrix (18)
- fMRI (18)
- foraging (18)
- imaging (18)
- land use (18)
- memory (18)
- metastasis (18)
- microRNA (18)
- mouse models (18)
- rat (18)
- time series (18)
- topological insulators (18)
- transcriptome (18)
- validation (18)
- Expression (17)
- MODIS (17)
- Optimierung (17)
- Organischer Halbleiter (17)
- P300 (17)
- Polymere (17)
- Quecksilbertellurid (17)
- Serotonin (17)
- Stress (17)
- Zellzyklus (17)
- adrenocortical carcinoma (17)
- bees (17)
- blood-brain barrier (17)
- bone (17)
- cell death (17)
- dSTORM (17)
- honeybee (17)
- psychology (17)
- resistance (17)
- Boron (16)
- Cytologie (16)
- DNA repair (16)
- Depression (16)
- Entzündung (16)
- Exziton (16)
- Merkel cell carcinoma (16)
- NFATc1 (16)
- Netzwerk (16)
- Tanzania (16)
- Verhalten (16)
- atherosclerosis (16)
- biomarkers (16)
- blood pressure (16)
- cells (16)
- chemotherapy (16)
- epithelial cells (16)
- heart (16)
- luminescence (16)
- mass spectrometry (16)
- mental health (16)
- messenger RNA (16)
- model (16)
- neuropathic pain (16)
- neuroprotection (16)
- prevalence (16)
- transcription (16)
- Angst (15)
- Arabidopsis thaliana (15)
- Decay (15)
- GPCR (15)
- Inhibitor (15)
- MYC (15)
- Myc (15)
- Neisseria gonorrhoeae (15)
- Optimale Kontrolle (15)
- Schlaganfall (15)
- Sentinel-2 (15)
- ants (15)
- diborenes (15)
- dopamine (15)
- echocardiography (15)
- escherichia coli (15)
- gene regulation (15)
- hadron-hadron scattering (15)
- immune response (15)
- in vivo (15)
- insects (15)
- lung cancer (15)
- miRNA (15)
- migration (15)
- mutation (15)
- neurons (15)
- olfaction (15)
- optogenetics (15)
- osteoporosis (15)
- proteins (15)
- proton-proton collision (15)
- simulation (15)
- stress (15)
- transcription factors (15)
- vision (15)
- Ameisen (14)
- Biodiversität (14)
- Chlamydia trachomatis (14)
- DNS-Reparatur (14)
- DNS-Schädigung (14)
- Datennetz (14)
- Deutschland (14)
- Epigenetik (14)
- Extension (14)
- Farbstoff (14)
- Femtosekundenspektroskopie (14)
- Gedächtnis (14)
- Halbleiter (14)
- Higgs boson (14)
- Makrophage (14)
- Mikroskopie (14)
- Monte-Carlo-Simulation (14)
- Regulation (14)
- Stammzelle (14)
- Supersymmetry (14)
- Transcription (14)
- Ultrakurzzeitspektroskopie (14)
- Vaccinia-Virus (14)
- Zelldifferenzierung (14)
- angiogenesis (14)
- association (14)
- borylation (14)
- chemistry (14)
- circadian clock (14)
- crystal structure (14)
- cultural studies (14)
- diversity (14)
- ecology (14)
- epigenetics (14)
- follow-up (14)
- guidelines (14)
- hippocampus (14)
- honey bees (14)
- in-vivo (14)
- mechanisms (14)
- mesenchymal stem cells (14)
- metagenomics (14)
- mushroom body (14)
- neurodegeneration (14)
- nutrition (14)
- ovarian cancer (14)
- platelet (14)
- prediction (14)
- risk factors (14)
- schizophrenia (14)
- sepsis (14)
- spectroscopy (14)
- Activation (13)
- Entwicklung (13)
- HgTe (13)
- Hydrogel (13)
- Kognition (13)
- Medicine (13)
- Motoneuron (13)
- Organische Solarzelle (13)
- PET/CT (13)
- Physics (13)
- Spintronik (13)
- Tumor (13)
- active zone (13)
- additive manufacturing (13)
- autoimmunity (13)
- bacteria (13)
- case report (13)
- cell staining (13)
- conservation (13)
- diet (13)
- ecosystem services (13)
- flow cytometry (13)
- fungi (13)
- human (13)
- humans (13)
- inhibition (13)
- mRNA (13)
- measles virus (13)
- melt electrowriting (13)
- metaanalysis (13)
- miRNS (13)
- molecular docking (13)
- monocytes (13)
- perylene bisimide (13)
- proliferation (13)
- recurrence (13)
- regulation (13)
- sphingolipids (13)
- super-resolution microscopy (13)
- tumor (13)
- ARPES (12)
- Ackerschmalwand (12)
- Aminosäuren (12)
- Apoptose (12)
- Aufmerksamkeit (12)
- BDNF (12)
- Bildgebendes Verfahren (12)
- Chemische Synthese (12)
- Computersimulation (12)
- Diabetes mellitus (12)
- Dichtefunktionalformalismus (12)
- Immuntherapie (12)
- Insekten (12)
- Konditionierung (12)
- Kulturwissenschaften (12)
- Lungenkrebs (12)
- Merocyanine (12)
- NMR-Tomographie (12)
- PRRT (12)
- PSMA (12)
- Proteine (12)
- Quality of Experience (12)
- RNS (12)
- Ratte (12)
- Rezeptor (12)
- Synapse (12)
- Theoretische Chemie (12)
- Thrombose (12)
- Topologie (12)
- West Africa (12)
- Zellskelett (12)
- antibiotics (12)
- biofabrication (12)
- blood–brain barrier (12)
- drug delivery (12)
- event-related potentials (12)
- exercise (12)
- fracture (12)
- genome (12)
- growth (12)
- in-vitro (12)
- inorganic chemistry (12)
- metabolomics (12)
- microscopy (12)
- neurology (12)
- osteoarthritis (12)
- performance (12)
- photoelectron spectroscopy (12)
- proteomics (12)
- receptor (12)
- risk (12)
- serotonin (12)
- structure elucidation (12)
- translation (12)
- treatment (12)
- vaccinia virus (12)
- ++ (11)
- Aggregation (11)
- Antikörper (11)
- Aspergillus (11)
- Biomarker (11)
- DFT (11)
- Dünne Schicht (11)
- Echinococcus (11)
- Einzelmolekülmikroskopie (11)
- Festkörperphysik (11)
- Gefühl (11)
- Genanalyse (11)
- Genetik (11)
- Knockout <Molekulargenetik> (11)
- Megakaryozyt (11)
- Microscopy (11)
- NMR-Spektroskopie (11)
- Namibia (11)
- Optische Spektroskopie (11)
- Perylenderivate (11)
- Physik (11)
- Robotik (11)
- SPECT (11)
- Squark (11)
- Supersymmetrie (11)
- T-cells (11)
- adolescents (11)
- asthma (11)
- cancer treatment (11)
- catalysis (11)
- development (11)
- diabetes (11)
- emotions (11)
- fibrosis (11)
- genomics (11)
- glioblastoma (11)
- glioblastoma multiforme (11)
- lymphoma (11)
- mechanism (11)
- membrane proteins (11)
- microbiome (11)
- nervous system (11)
- neural networks (11)
- neuroendocrine tumor (11)
- neutrophils (11)
- optimization (11)
- pancreatic cancer (11)
- pollen (11)
- pollination (11)
- polymorphism (11)
- pregnancy (11)
- randomized controlled trial (11)
- reliability (11)
- review (11)
- supramolecular chemistry (11)
- symbiosis (11)
- synaptic plasticity (11)
- systematic review (11)
- tight junctions (11)
- topological insulator (11)
- total knee arthroplasty (11)
- traumatic brain injury (11)
- tumor microenvironment (11)
- vitamin D (11)
- water oxidation (11)
- ALS (10)
- Alzheimer’s disease (10)
- Angststörung (10)
- Bakterien (10)
- Elektronentransfer (10)
- Fluorescence (10)
- Helicobacter pylori (10)
- Immunotherapy (10)
- Immunsystem (10)
- Inflammation (10)
- Insulin (10)
- Kutikula (10)
- MAP-Kinase (10)
- Mensch-Maschine-Kommunikation (10)
- Microarray (10)
- Model (10)
- Oxidativer Stress (10)
- Perylenbisimid (10)
- Pflanzen (10)
- Platelets (10)
- RNA-seq (10)
- Sentinel-1 (10)
- Supraleitung (10)
- T cell (10)
- Transkription <Genetik> (10)
- X-ray crystallography (10)
- Xiphophorus (10)
- amygdala (10)
- animal model (10)
- antimicrobial resistance (10)
- atrial fibrillation (10)
- boranes (10)
- carbenes (10)
- cardiomyopathy (10)
- cartilage (10)
- cell cycle (10)
- complex (10)
- decision-making (10)
- density functional calculations (10)
- dynamics (10)
- education (10)
- electronic properties and materials (10)
- emotion regulation (10)
- fear (10)
- fear conditioning (10)
- genome-wide association (10)
- global change (10)
- hemodialysis (10)
- hydrogels (10)
- induced pluripotent stem cells (10)
- kidney (10)
- kinetics (10)
- liver (10)
- lymph nodes (10)
- lymphocytes (10)
- microglia (10)
- molecular imaging (10)
- mutations (10)
- nanoparticles (10)
- next generation sequencing (10)
- nitric oxide (10)
- oncolytic virus (10)
- p53 (10)
- phenotype (10)
- plasticity (10)
- polymers (10)
- prefrontal cortex (10)
- rats (10)
- reactive oxygen species (10)
- recombination (10)
- relapse (10)
- rheumatoid arthritis (10)
- safety (10)
- signaling (10)
- synthesis (10)
- transplantation (10)
- ubiquitin (10)
- Ökologie (10)
- 3D-Druck (9)
- Adenosine receptors (9)
- Alps (9)
- Arteriosklerose (9)
- Beyond Standard Model (9)
- Bildverarbeitung (9)
- Bor (9)
- CRISPR/Cas9 (9)
- Elektronenkorrelation (9)
- Elektrophysiologie (9)
- Elementarteilchenphysik (9)
- Emotion (9)
- Extrazelluläre Matrix (9)
- Fuchsbandwurm (9)
- G-Protein gekoppelte Rezeptoren (9)
- Geruchswahrnehmung (9)
- Globalisierung (9)
- Google Earth Engine (9)
- HPLC (9)
- Immunbiologie (9)
- Immunreaktion (9)
- In vitro (9)
- Inhibition (9)
- Interaktion (9)
- Japankärpfling (9)
- LASP1 (9)
- MRSA (9)
- Metabolismus (9)
- Mitose (9)
- NK cells (9)
- Nahrungserwerb (9)
- Parkinson-Krankheit (9)
- Quanten-Hall-Effekt (9)
- Quantenchemie (9)
- Quantenpunkt (9)
- Raman-Spektroskopie (9)
- Small RNA (9)
- Starke Kopplung (9)
- TNF (9)
- Tagesrhythmus (9)
- Virulenz (9)
- Westafrika (9)
- age (9)
- agriculture (9)
- amyotrophic lateral sclerosis (9)
- antennal lobe (9)
- aromaticity (9)
- bipolar disorder (9)
- body size (9)
- calcium (9)
- central nervous system (9)
- cerebrospinal fluid (9)
- circadian rhythms (9)
- clinical trial (9)
- cuticular hydrocarbons (9)
- database (9)
- dispersal (9)
- dosimetry (9)
- earth observation (9)
- energy (9)
- enzyme replacement therapy (9)
- evaluation (9)
- experimental autoimmune encephalomyelitis (9)
- fatigue (9)
- fluorescence microscopy (9)
- forest (9)
- high energy physics (9)
- hypoxia (9)
- immunology (9)
- insulin (9)
- ischemia (9)
- leaf-cutting ants (9)
- metapopulation (9)
- navigation (9)
- neuropathy (9)
- neuroscience (9)
- organic semiconductors (9)
- outcome (9)
- pathogens (9)
- pathway (9)
- pharmacokinetics (9)
- platelet aggregation (9)
- preterm infants (9)
- reconstruction (9)
- replication (9)
- reveals (9)
- social interaction (9)
- subthalamic nucleus (9)
- systematic uncertainty (9)
- temperature (9)
- thrombosis (9)
- transcriptomics (9)
- transmission (9)
- tumors (9)
- type 2 diabetes (9)
- walking (9)
- water (9)
- ATLAS (8)
- Adenosinrezeptor (8)
- Affekt (8)
- Alzheimer's disease (8)
- Arzneimitteldesign (8)
- Aufmerksamkeits-Defizit-Syndrom (8)
- Bacteria (8)
- Bioinformatics (8)
- Blazar (8)
- Calcium (8)
- Camponotus floridanus (8)
- Chlamydia (8)
- Cross-Section (8)
- DNS (8)
- Deep learning (8)
- EAE (8)
- Elektronenspinresonanz (8)
- Elektronischer Transport (8)
- Embryonalentwicklung (8)
- Europe (8)
- Extremwertstatistik (8)
- FRET (8)
- Fluoreszenz-Resonanz-Energie-Transfer (8)
- Fotovoltaik (8)
- Galliumarsenid (8)
- Geldpolitik (8)
- HNSCC (8)
- Herzinfarkt (8)
- Heterostruktur (8)
- Induzierte pluripotente Stammzelle (8)
- Infektion (8)
- Kleinsatellit (8)
- Krebs (8)
- Ladungstransfer (8)
- Landsat (8)
- Ligand <Biochemie> (8)
- Listeria monocytogenes (8)
- MS (8)
- Machine Learning (8)
- Malaria (8)
- Mass (8)
- Mensch (8)
- Mice (8)
- Motivation (8)
- Muscarinrezeptor (8)
- N-heterocyclic carbenes (8)
- Nanopartikel (8)
- Neurodegeneration (8)
- Nigeria (8)
- Onkogen (8)
- Pain (8)
- Parton distributions (8)
- Pilzkörper (8)
- Quran (8)
- ROS (8)
- SAR (8)
- Salmonella (8)
- Schizophrenie (8)
- South Africa (8)
- Squaraine (8)
- Stroke (8)
- Therapie (8)
- Therapy (8)
- Thrombosis (8)
- Transkription (8)
- Trypanosoma (8)
- Ultrakurzer Lichtimpuls (8)
- Zellkultur (8)
- actin (8)
- acute kidney injury (8)
- adolescence (8)
- analysis of variance (8)
- animal models (8)
- autoantibodies (8)
- bioinformatics (8)
- bone marrow (8)
- cancer therapy (8)
- cardiac hypertrophy (8)
- cardiovascular disease (8)
- cell biology (8)
- cell wall (8)
- central complex (8)
- charge transfer (8)
- chromatin (8)
- coherence (8)
- computed tomography (8)
- cortisol (8)
- cytotoxic T cells (8)
- decay (8)
- decision making (8)
- dementia (8)
- division of labor (8)
- domain (8)
- electroencephalography (8)
- electronic structure (8)
- forest management (8)
- gephyrin (8)
- glycine receptor (8)
- head and neck cancer (8)
- heart rate (8)
- histology (8)
- human behaviour (8)
- hypertension (8)
- immune evasion (8)
- impact (8)
- in vivo imaging (8)
- inhibitor (8)
- innate immunity (8)
- insect (8)
- interaction (8)
- jet energy scale (8)
- kinematic alignment (8)
- learning and memory (8)
- mHealth (8)
- major depression (8)
- malaria (8)
- meiosis (8)
- microarray (8)
- mitosis (8)
- molecular beam epitaxy (8)
- molecular biology (8)
- molecular dynamics (8)
- monitoring (8)
- motivation (8)
- oncology (8)
- optimal control (8)
- organic solar cells (8)
- organoids (8)
- periodontitis (8)
- peripheral nervous system (8)
- permafrost (8)
- permeability (8)
- photocatalysis (8)
- platelet activation (8)
- polycyclic aromatic hydrocarbons (8)
- presence (8)
- prevention (8)
- progression (8)
- quality assurance (8)
- radioligand therapy (8)
- receptors (8)
- rehabilitation (8)
- senescence (8)
- serum (8)
- social insects (8)
- species richness (8)
- spintronics (8)
- technology (8)
- tinnitus (8)
- tool (8)
- transport (8)
- zebrafish (8)
- Übergangsmetallkomplexe (8)
- 3D tissue model (7)
- Akt (7)
- Aktiver galaktischer Kern (7)
- Alzheimerkrankheit (7)
- Angeregter Zustand (7)
- Angiogenese (7)
- Arzneimittel (7)
- Asthma (7)
- Ausbreitung (7)
- Autonomer Roboter (7)
- BMP (7)
- Biofilm (7)
- Biomaterial (7)
- Bioverfügbarkeit (7)
- Caenorhabditis elegans (7)
- Chronobiologie (7)
- Chrysomelidae (7)
- Cloud Computing (7)
- Cytokine (7)
- Dendritic cells (7)
- EGFR (7)
- Enzym (7)
- Ernährung (7)
- Furcht (7)
- Gammastrahlung (7)
- Genmutation (7)
- Genom (7)
- Hubbard-Modell (7)
- Informationsverarbeitung (7)
- Invasion (7)
- Katalyse (7)
- Klimawandel (7)
- Koran (7)
- Künstliche Intelligenz (7)
- LC-MS/MS (7)
- Landnutzung (7)
- Leishmania (7)
- MSC (7)
- Metapopulation (7)
- Methylierung (7)
- Mobiler Roboter (7)
- Monte Carlo (7)
- NDVI (7)
- NMR-Bildgebung (7)
- Nash-Gleichgewicht (7)
- Neuroethologie (7)
- Neutrino (7)
- Operations Management (7)
- Optogenetik (7)
- Organisches Molekül (7)
- Pathogenität (7)
- Performance Evaluation (7)
- Pheromon (7)
- Phylogenie (7)
- Prevalence (7)
- Proliferation (7)
- Protein (7)
- Radioastronomie (7)
- Remote Sensing (7)
- SMN (7)
- Spinale Muskelatrophie (7)
- Stoffwechsel (7)
- Survival (7)
- Synthese (7)
- Text Mining (7)
- Textverstehen (7)
- Tuberkelbakterium (7)
- UAV (7)
- Ubiquitin (7)
- United States (7)
- Visualisierung (7)
- Wahrnehmung (7)
- Zebrabärbling (7)
- Zeitreihenanalyse (7)
- Zellmigration (7)
- absorption (7)
- acute ischemic stroke (7)
- adhesion (7)
- aggregation (7)
- algorithm (7)
- altitudinal gradient (7)
- animal behavior (7)
- antibacterial activity (7)
- antigen (7)
- arabidopsis thaliana (7)
- astrocytes (7)
- bioprinting (7)
- biosynthesis (7)
- blood brain barrier (7)
- blood flow (7)
- body mass index (7)
- bone regeneration (7)
- brain development (7)
- brain-computer interface (7)
- cAMP (7)
- cGMP (7)
- cell membranes (7)
- change detection (7)
- chemokine receptor (7)
- chronic heart failure (7)
- classical conditioning (7)
- cognitive control (7)
- cognitive impairment (7)
- communication (7)
- comparative genomics (7)
- complexity (7)
- cytokinesis (7)
- design (7)
- developmental biology (7)
- diabetes mellitus (7)
- drought (7)
- drug (7)
- efficacy (7)
- electron microscopy (7)
- embodiment (7)
- endocytosis (7)
- endurance (7)
- energy transfer (7)
- extinction (7)
- extracellular vesicles (7)
- facial expressions (7)
- femtosecond spectroscopy (7)
- fibromyalgia syndrome (7)
- fluorescent probes (7)
- gastric cancer (7)
- gender (7)
- genes (7)
- genotoxicity (7)
- glaucoma (7)
- heterocycles (7)
- hyaluronic acid (7)
- hypophosphatasia (7)
- immersion (7)
- immunofluorescence (7)
- immunomodulation (7)
- immunoprecipitation (7)
- latency (7)
- locomotion (7)
- luciferase (7)
- lung (7)
- mapping (7)
- mechanotransduction (7)
- melt electrospinning writing (7)
- meta-analysis (7)
- methylation (7)
- microbiology (7)
- microenvironment (7)
- monoclonal antibodies (7)
- multicenter (7)
- mutualism (7)
- myelin (7)
- near-infrared spectroscopy (7)
- neuroblastoma (7)
- neuromuscular junction (7)
- oncolytic virotherapy (7)
- optical spectroscopy (7)
- organic chemistry (7)
- panic disorder (7)
- pathogenesis (7)
- population (7)
- precision medicine (7)
- psychiatric disorders (7)
- public health (7)
- quantum dot (7)
- random forest (7)
- recognition (7)
- responses (7)
- secondary prevention (7)
- secondary structure (7)
- secretion (7)
- segmentation (7)
- selection (7)
- semiconductors (7)
- sex differences (7)
- sleep (7)
- small RNA (7)
- social anxiety (7)
- social cognition (7)
- software (7)
- spinal muscular atrophy (7)
- staphylococcus aureus (7)
- superconductivity (7)
- susceptibility (7)
- targeted therapy (7)
- telomeres (7)
- thermodynamics (7)
- thrombo-inflammation (7)
- transcriptional regulation (7)
- transient absorption (7)
- trial (7)
- visual system (7)
- wearable (7)
- working memory (7)
- ATLAS <Teilchendetektor> (6)
- AdS-CFT-Korrespondenz (6)
- Antibiotikum (6)
- Anxiety (6)
- Arbeitsteilung (6)
- B-Lymphozyt (6)
- BRCA1 (6)
- Biology (6)
- Blattschneiderameisen (6)
- Blut-Hirn-Schranke (6)
- Brain (6)
- Bruchpilot (6)
- CMV (6)
- Cataglyphis (6)
- Chiralität <Chemie> (6)
- Click-Chemie (6)
- Covid-19 (6)
- Cytoskeleton (6)
- DNA binding (6)
- ELISPOT (6)
- Earth observation (6)
- Ecology (6)
- Elektrochemie (6)
- Elektronenstruktur (6)
- Epidermaler Wachstumsfaktor-Rezeptor (6)
- Fibroblastenwachstumsfaktor (6)
- Funktionelle Kernspintomografie (6)
- GPVI (6)
- Gehirn-Computer-Schnittstelle (6)
- Gen (6)
- Genotoxicity (6)
- Geochemie (6)
- Geruch (6)
- Geruchssinn (6)
- Geschichte (6)
- Glioblastoma (6)
- Gluino Production (6)
- Graphen (6)
- Hadron colliders (6)
- HeLa cells (6)
- Heart (6)
- Heart failure (6)
- Herz (6)
- Hfq (6)
- Higgs bosons (6)
- Higgs physics (6)
- Hippocampus (6)
- Hochtemperatursupraleiter (6)
- Honeybee (6)
- Honigbiene (6)
- Hubbard model (6)
- Hymenoptera (6)
- Hypothalamus (6)
- IL-10 (6)
- ITS2 (6)
- Immunology (6)
- India (6)
- Instrumentelle Analytik (6)
- IoT (6)
- Klima (6)
- Komplexität (6)
- Komplexitätstheorie (6)
- Konfokale Mikroskopie (6)
- Konjugierte Polymere (6)
- LPS (6)
- Large Hadron Collider (6)
- Laser (6)
- Latrophilin (6)
- Lehrerbildung (6)
- Ligand (6)
- Lithium-Ionen-Akkumulator (6)
- Löslichkeit (6)
- MASS (6)
- MYCN (6)
- Macrophage (6)
- Magnetic resonance imaging (6)
- Magnetismus (6)
- Mechanisms (6)
- Meeresschwämme (6)
- Memory (6)
- Micronuclei (6)
- Mitochondria (6)
- Monoklonaler Antikörper (6)
- Monte-Carlo (6)
- Multiple myeloma (6)
- NAFLD (6)
- NFAT (6)
- NLO Computations (6)
- NMR (6)
- NMR spectroscopy (6)
- NRF2 (6)
- NSCLC (6)
- Natürliche Killerzelle (6)
- Neuronale Plastizität (6)
- Newton-Verfahren (6)
- Numerisches Verfahren (6)
- Onkolyse (6)
- Optogenetics (6)
- Organische Synthese (6)
- PD-1 (6)
- PD-L1 (6)
- Parasit (6)
- Pharmakokinetik (6)
- Pharmakologie (6)
- Physiologie (6)
- Platelet (6)
- Pollen (6)
- Prognose (6)
- Pulsformung (6)
- RNA sequencing (6)
- RNA-binding proteins (6)
- Raf <Biochemie> (6)
- Rechnernetz (6)
- Rekombination (6)
- Rezension (6)
- Rituximab (6)
- Routing (6)
- Röntgen-Photoelektronenspektroskopie (6)
- Röntgenspektroskopie (6)
- SDN (6)
- SSTR (6)
- Salmonella typhimurium (6)
- Satellit (6)
- Self-assembly (6)
- Soziale Insekten (6)
- Spintronics (6)
- Stabilität (6)
- Stressreaktion (6)
- Symbiose (6)
- Systembiologie (6)
- T lymphocytes (6)
- TRAIL (6)
- TWEAK (6)
- Transcriptome (6)
- Transplantat-Wirt-Reaktion (6)
- Transport (6)
- TrkB (6)
- Tumorzelle (6)
- USA (6)
- Ultrafast spectroscopy (6)
- VEGF (6)
- Verteiltes System (6)
- XPS (6)
- Zellteilung (6)
- Zentralnervensystem (6)
- Zwei-Sechs-Halbleiter (6)
- actinomycetes (6)
- adaptation (6)
- adsorption (6)
- adults (6)
- aggression (6)
- alkaloids (6)
- allergy (6)
- allogeneic stem cell transplantation (6)
- animal behaviour (6)
- antibiotic resistance (6)
- antibody (6)
- antidepressant (6)
- astrocytoma (6)
- bacterial pathogens (6)
- basal ganglia (6)
- behavioral conditioning (6)
- biocompatibility (6)
- biomaterials (6)
- body weight (6)
- bone mineral density (6)
- boronate esters (6)
- carcinoma (6)
- cardiac surgery (6)
- cardiovascular diseases (6)
- cell proliferation (6)
- ceramide (6)
- cerebellum (6)
- chemokines (6)
- chlamydia (6)
- chronic pain (6)
- circular dichroism (6)
- click chemistry (6)
- co-culture (6)
- coagulation (6)
- cognitive decline (6)
- coping (6)
- copper (6)
- coronary artery disease (6)
- cosmology (6)
- crystallization (6)
- cytokinins (6)
- deadwood (6)
- degradation (6)
- density functional theory (6)
- diagnostics (6)
- diborynes (6)
- down regulation (6)
- drosophila melanogaster (6)
- drug design (6)
- dyes (6)
- dystonia (6)
- eHealth (6)
- electrophysiology (6)
- experience (6)
- exposure (6)
- eye movements (6)
- eye tracking (6)
- eyes (6)
- facial expression (6)
- factor XII (6)
- family (6)
- fluorine (6)
- fungal infection (6)
- glaucoma surgery (6)
- glioma (6)
- glucocorticoid receptor (6)
- grazing (6)
- homogeneous catalysis (6)
- honeybees (6)
- host-pathogen interaction (6)
- hydrogel (6)
- hymenoptera (6)
- hyperexpression techniques (6)
- ideomotor theory (6)
- immune cells (6)
- immune system (6)
- immunity (6)
- immunosuppression (6)
- in vitro selection (6)
- inflammatory bowel disease (6)
- influenza (6)
- injury (6)
- integrins (6)
- invasion (6)
- iron (6)
- kidneys (6)
- kinase (6)
- lesions (6)
- leukemia (6)
- localization microscopy (6)
- macrophage (6)
- mechanical thrombectomy (6)
- medaka (6)
- megakaryocytes (6)
- membrane potential (6)
- meningococcal disease (6)
- models (6)
- motoneuron (6)
- movement disorders (6)
- mushroom bodies (6)
- neurobiology (6)
- neurogenesis (6)
- neuronal differentiation (6)
- octopamine (6)
- oilseed rape (6)
- outcomes (6)
- pediatric (6)
- pediatrics (6)
- personalized medicine (6)
- phenology (6)
- phylogenetic trees (6)
- phylogeny (6)
- plasmodium falciparum (6)
- polarization (6)
- primary care (6)
- psoriasis (6)
- pulse shaping (6)
- quantum dots (6)
- radiation (6)
- radicals (6)
- recruitment (6)
- regenerative medicine (6)
- repair (6)
- resilience (6)
- sRNA (6)
- salt stress (6)
- scaffold (6)
- screening (6)
- sequence (6)
- sequence alignment (6)
- signaling pathway (6)
- small interfering RNAs (6)
- smoking (6)
- social attention (6)
- sodium (6)
- states (6)
- structure (6)
- synapse (6)
- systems biology (6)
- target (6)
- taxonomy (6)
- therapeutic drug monitoring (6)
- tolerance (6)
- tomography (6)
- translational research (6)
- vaccine (6)
- valence (6)
- variability (6)
- Übergangsmetall (6)
- 18F-FDG (5)
- 53BP1 (5)
- AI (5)
- AMPK (5)
- Actin (5)
- Aggregat <Chemie> (5)
- Algorithmus (5)
- Alzheimer disease (5)
- Alzheimer-Krankheit (5)
- Amino acids (5)
- Antibody (5)
- Antigen CD8 (5)
- Assoziatives Gedächtnis (5)
- Astrophysik (5)
- Atherosclerosis (5)
- B-cell lymphoma (5)
- B7-H1 (5)
- BCI (5)
- BRAF (5)
- Bauchspeicheldrüsenkrebs (5)
- Biofabrication (5)
- Bordetella pertussis (5)
- Borylene (5)
- Borylierung (5)
- Brain-derived neurotrophic factor (5)
- Breaking (5)
- Burkina Faso (5)
- CD95 (5)
- CML (5)
- CNS (5)
- CRISPR/Cas-Methode (5)
- CSF (5)
- CT (5)
- Campylobacter jejuni (5)
- Children (5)
- Chromatin (5)
- Chromophor (5)
- Climate change (5)
- Cognitive control (5)
- Coherent Multidimensional Spectroscopy (5)
- Computational Chemistry (5)
- Cytotoxizität (5)
- Dark Matter (5)
- Demökologie (5)
- Diffusion (5)
- Dopamine (5)
- Durchblutung (5)
- Dünndarm (5)
- ERP (5)
- Earth Observation (5)
- Emotionsregulation (5)
- Endothel (5)
- Energy (5)
- Enterobacteriaceae (5)
- Entscheidungsunterstützung (5)
- Enzyme replacement therapy (5)
- Epigenetic (5)
- Erwachsener (5)
- Evaluation (5)
- Fanconi-Anämie (5)
- Femtosekundenbereich (5)
- Fermionensystem (5)
- Fitness (5)
- Fluoreszenzspektroskopie (5)
- Flüssigkristall (5)
- Fn14 (5)
- Formicidae (5)
- Fortpflanzung (5)
- Fourier-Spektroskopie (5)
- GABA (5)
- GWAS (5)
- Gammaastronomie (5)
- Gene (5)
- Gene-expression (5)
- Genetics (5)
- Geomorphologie (5)
- Gephyrin (5)
- Gold (5)
- Graph (5)
- Graphenzeichnen (5)
- HUWE1 (5)
- Herzhypertrophie (5)
- Hydrogeologie (5)
- Hypoxia (5)
- Hypoxie (5)
- Hämostase (5)
- IL-2 (5)
- IL-4 (5)
- Imatinib (5)
- Impurity Profiling (5)
- In vivo (5)
- In-vivo (5)
- InSAR (5)
- Indien (5)
- Interleukin 4 (5)
- Iran (5)
- Jugend (5)
- Knochen-Morphogenese-Proteine (5)
- Kondensierte Materie (5)
- Kondo-Effekt (5)
- Kosmologie (5)
- Käfer (5)
- LC-MS (5)
- Landwirtschaft (5)
- Learning (5)
- Legionella pneumophila (5)
- Lymphozyt (5)
- MAGIC-Teleskop (5)
- MBE (5)
- Magnetische Resonanz (5)
- Magnetischer Halbleiter (5)
- Makroökonomie (5)
- Manganarsenide (5)
- Manganverbindungen (5)
- Massenspektrometrie (5)
- Mathematik (5)
- Mathematische Modellierung (5)
- Meiose (5)
- Meiosis (5)
- Meningitis (5)
- Metabolism (5)
- Metagenom (5)
- Microtubules (5)
- Mitochondrium (5)
- Modell (5)
- Molekulardynamik (5)
- Molekül (5)
- Monitoring (5)
- Multiple sclerosis (5)
- N-Myc (5)
- NF-KAPPA-B (5)
- NFκB (5)
- NLO computations (5)
- NLRP3 (5)
- Nachhaltigkeit (5)
- Nahfeldoptik (5)
- Nahrung (5)
- Namibia <Nordwest> (5)
- Nanodraht (5)
- Nanostruktur (5)
- Naphthylisochinolinalkaloide (5)
- Nervendegeneration (5)
- Nervenzelle (5)
- Neuroanatomie (5)
- Neurogenetik (5)
- Neuronales Netz (5)
- Neuropeptide (5)
- Nichtlineare Optimierung (5)
- Nichtlineare Spektroskopie (5)
- Non-coding RNA (5)
- Nucleinsäuren (5)
- OLED (5)
- Oberflächenphysik (5)
- Olfaction (5)
- Optik (5)
- Osteoarthritis (5)
- P4 (5)
- PCR (5)
- Perovskite (5)
- Perowskit (5)
- Pflanzenfressende Insekten (5)
- Pharmakodynamik (5)
- Photochemie (5)
- Photochemistry (5)
- Photovoltaik (5)
- PolSAR (5)
- QM/MM (5)
- Quality of life (5)
- Quanteninformation (5)
- RADS (5)
- RNA interference (5)
- RNA polymerase II (5)
- Radiotherapy (5)
- Raman (5)
- RapidEye (5)
- Rastertunnelmikroskop (5)
- Rat (5)
- Regulatorischer T-Lymphozyt (5)
- Rhodium (5)
- Ringöffnungspolymerisation (5)
- SERS (5)
- Saccharomyces cerevisiae (5)
- Salmonella enterica (5)
- Semiconductor (5)
- Semimagnetischer Halbleiter (5)
- Siliciumcarbid (5)
- Software (5)
- Software Defined Networking (5)
- Sozialpsychologie (5)
- Spin (5)
- Spin-Bahn-Wechselwirkung (5)
- Standardmodell <Elementarteilchenphysik> (5)
- Strahlentherapie (5)
- Structural Biology (5)
- T cell activation (5)
- T cell receptor (5)
- TLR4 (5)
- TNF-α (5)
- TNFR2 (5)
- TerraSAR-X (5)
- Theoretical Chemistry (5)
- Theoretische Informatik (5)
- Tissue engineering (5)
- Top physics (5)
- Top quark (5)
- Toxin (5)
- Transkriptomanalyse (5)
- Treatment (5)
- Trypanosomen (5)
- UV-VIS-Spektroskopie (5)
- Ultraschall (5)
- VASP (5)
- VSG (5)
- Vaccine (5)
- Vaccinia virus (5)
- Vasodilatator-stimuliertes Phosphoprotein (5)
- Venusfliegenfalle (5)
- Virtual Reality (5)
- Virulenzfaktor (5)
- Visualization (5)
- Visuelle Aufmerksamkeit (5)
- Wilms tumor (5)
- Wirkstoff (5)
- X-ray (5)
- Zebrafish (5)
- Zelle (5)
- Zellkern (5)
- Zelltod (5)
- Zellwand (5)
- accuracy (5)
- actin cytoskeleton (5)
- acute myeloid leukemia (5)
- adalimumab (5)
- adipocytes (5)
- adipose tissue (5)
- ageing (5)
- algorithms (5)
- amino acids (5)
- anatomy (5)
- annotation (5)
- antidepressants (5)
- antigenic variation (5)
- antimicrobial stewardship (5)
- antimicrobials (5)
- anxiety disorders (5)
- aorta (5)
- arousal (5)
- auditory (5)
- augmented reality (5)
- autoantibody (5)
- automation (5)
- autonomic nervous system (5)
- balance (5)
- bariatric surgery (5)
- bee (5)
- bioink (5)
- biokinetics (5)
- biological locomotion (5)
- biophysics (5)
- bioreactor (5)
- bismuth (5)
- borylene (5)
- brain computer interface (5)
- brain tumor (5)
- bronchopulmonary dysplasia (5)
- caloric restriction (5)
- cancer stem cells (5)
- carbon dioxide (5)
- cardiomyocytes (5)
- cardiovascular events (5)
- catecholamines (5)
- cell adhesion (5)
- cell cultures (5)
- cell cycle and cell division (5)
- cell differentiation (5)
- cell migration (5)
- ceramides (5)
- cerebral ischemia (5)
- chemical communication (5)
- chemical ecology (5)
- chirality (5)
- chondrocytes (5)
- ciliary neurotrophic factor (5)
- circadian rhythm (5)
- climate (5)
- cognition (5)
- collagens (5)
- comparison (5)
- competition (5)
- complexes (5)
- condensed matter physics (5)
- coronary heart disease (5)
- correlation (5)
- critical illness (5)
- cross-coupling (5)
- cystic fibrosis (5)
- damage (5)
- demyelination (5)
- dendritic cell (5)
- dental education (5)
- detoxification (5)
- dialysis (5)
- disability (5)
- drug discovery (5)
- drug repurposing (5)
- eating disorders (5)
- ecological momentary assessment (5)
- emission (5)
- empathy (5)
- energy metabolism (5)
- enzyme-linked immunoassays (5)
- enzymes (5)
- epithelial-mesenchymal transition (5)
- exciton (5)
- experimental design (5)
- fear generalization (5)
- fluorescence imaging (5)
- food security (5)
- food-cues (5)
- forensic neuropathology (5)
- functional magnetic resonance imaging (5)
- gait (5)
- galactomannan (5)
- gastrointestinal tract (5)
- gene-expression (5)
- generation (5)
- geomorphology (5)
- global warming (5)
- glucose (5)
- glycoprotein VI (5)
- graph drawing (5)
- guard cells (5)
- guideline adherence (5)
- health-related quality of life (5)
- hearing loss (5)
- heterochromatin (5)
- homeostasis (5)
- honey bee (5)
- human-computer interaction (5)
- hydroboration (5)
- implementation (5)
- incidence (5)
- inflammasome (5)
- infrared spectroscopy (5)
- insulin resistance (5)
- knockout (5)
- knockout mice (5)
- larvae (5)
- leishmaniasis (5)
- lipids (5)
- localization (5)
- long-term outcome (5)
- lysosome (5)
- marine sponges (5)
- masked priming (5)
- mast cells (5)
- megakaryocyte (5)
- membrane (5)
- meningitis (5)
- mental disorders (5)
- methionine (5)
- methylphenidate (5)
- microbiota (5)
- microglomeruli (5)
- middle cerebral artery occlusion (5)
- migrants (5)
- mineralization (5)
- mobility (5)
- molecular medicine (5)
- molecular neuroscience (5)
- motoneurons (5)
- motor control (5)
- movement ecology (5)
- mycotoxin (5)
- myocarditis (5)
- nanostructures (5)
- natural disturbance (5)
- natural products (5)
- nature conservation (5)
- network (5)
- neuroanatomy (5)
- neuroethology (5)
- neuropeptides (5)
- neuropsychiatric disorders (5)
- norepinephrine (5)
- nuclear envelope (5)
- nutrients (5)
- object detection (5)
- oncogenes (5)
- oncolysis (5)
- organization (5)
- paraganglioma (5)
- parasitic diseases (5)
- peptide (5)
- perception and action (5)
- pharmacology (5)
- pheochromocytoma (5)
- photoinduced electron transfer (5)
- plant-insect interactions (5)
- plants (5)
- polycaprolactone (5)
- polyneuropathy (5)
- polyomavirus (5)
- population pharmacokinetics (5)
- preclinical research (5)
- prostate-specific membrane antigen (5)
- protease (5)
- protein binding (5)
- protein domains (5)
- protein kinase (5)
- pulmonary hypertension (5)
- quantification (5)
- qubit (5)
- radial (5)
- radical (5)
- recombinant proteins (5)
- recovery (5)
- refractory (5)
- regression analysis (5)
- replacement (5)
- resolution (5)
- resveratrol (5)
- reward (5)
- scale (5)
- self-organization (5)
- serotonin transporter (5)
- shear stress (5)
- signalling (5)
- single-crystal X-ray study (5)
- skeletal muscle (5)
- skin (5)
- small fiber neuropathy (5)
- soil (5)
- solar cells (5)
- solubility (5)
- somatic mutations (5)
- somatostatin receptor (5)
- soziale Insekten (5)
- spin (5)
- spinal cord (5)
- sponges (5)
- stability (5)
- stem-cell transplantation (5)
- structural biology (5)
- supersymmetry (5)
- surfactants (5)
- survey (5)
- sympathetic nervous system (5)
- synaptic proteins (5)
- synaptic vesicles (5)
- system (5)
- text comprehension (5)
- trabeculectomy (5)
- training (5)
- transcription factor (5)
- translocation (5)
- transverse momentum (5)
- tremor (5)
- tsetse fly (5)
- vaccination (5)
- vancomycin (5)
- variants (5)
- vestibular schwannoma (5)
- virulence factors (5)
- virus (5)
- visualization (5)
- wild bees (5)
- winter wheat (5)
- women (5)
- 1 (4)
- 3D (4)
- 3D cell culture (4)
- ACTH (4)
- AIDS (4)
- AMD (4)
- AVHRR (4)
- Actin-bindende Proteine (4)
- Acyrthosiphon pisum (4)
- AdS-CFT Correspondence (4)
- AdS/CFT (4)
- Adenylate cyclase (4)
- Adhäsion (4)
- Adult (4)
- Africa (4)
- Aggression (4)
- Alkohol (4)
- Allergie (4)
- Alzheimers disease (4)
- Anaphylaxis (4)
- Ancistrocladaceae (4)
- Antarctica (4)
- Antennallobus (4)
- Antimikrobieller Wirkstoff (4)
- Ants (4)
- Anura (4)
- Approximationsalgorithmus (4)
- Arbeitsmarkt (4)
- Atlas detector (4)
- Aufmerksamkeitsdefizit-Syndrom (4)
- Autoantikörper (4)
- Autoimmunity (4)
- Autoimmunität (4)
- B cell (4)
- B-MYB (4)
- B-Zell-Lymphom (4)
- B-cells (4)
- BCG (4)
- BMP-2 (4)
- Bacillus subtilis (4)
- Barth syndrome (4)
- Behavior (4)
- Bestäubung (4)
- Bevacizumab (4)
- Bewusstsein (4)
- Bienen <Familie> (4)
- Bilanzpolitik (4)
- Biogenese (4)
- Biologische Uhr (4)
- Biomechanik (4)
- Biotransformation (4)
- Blattkäfer (4)
- Borane (4)
- Borylation (4)
- Boson (4)
- Botanik (4)
- Brustkrebs (4)
- C-C coupling (4)
- C-MYC (4)
- C-reactive protein (4)
- CD1d (4)
- CD28 (4)
- CMR (4)
- COPD (4)
- CT angiography (4)
- CTLA-4 (4)
- Cadherine (4)
- Calciumkanal (4)
- Cancer genetics (4)
- Candida auris (4)
- Carcinogen (4)
- Catalysis (4)
- Charcot-Marie-Tooth (4)
- Chemische Reinheit (4)
- Chemische Ökologie (4)
- Chemistry (4)
- Chemotherapy (4)
- Compressed Sensing (4)
- Computational chemistry (4)
- Conditioning (4)
- Costa Rica (4)
- Crowdsourcing (4)
- CubeSat (4)
- Cushing’s syndrome (4)
- DFT calculations (4)
- DNA transcription (4)
- DNA-binding proteins (4)
- Data Mining (4)
- Datenbank (4)
- Dendritic cell (4)
- Design (4)
- Diagnosis (4)
- Diborane (4)
- Dienstgüte (4)
- Differentialgleichung (4)
- Distributions (4)
- Diversity (4)
- Dopamin (4)
- Dotierung (4)
- Drahtloses Sensorsystem (4)
- Dunkle Materie (4)
- ECM (4)
- EMG (4)
- EPR (4)
- ERK (4)
- ERK1/2 (4)
- Electron microscopy (4)
- Electrospinning (4)
- Electroweak interaction (4)
- Elektroencephalographie (4)
- Elektronendichte (4)
- Elektronenspin (4)
- Elektronentransport (4)
- Embryonale Stammzelle (4)
- Endocytose (4)
- Entwicklungsbiologie (4)
- Enzyminhibitor (4)
- Epigenetics (4)
- Epitaxy (4)
- Euler equations (4)
- Excitons (4)
- Expansion Microscopy (4)
- Experimentelle Psychologie (4)
- Extremwerttheorie (4)
- FDG (4)
- FGFR (4)
- Fanconi anemia (4)
- Feminismus (4)
- Festkörpertheorie (4)
- Fibroblasten (4)
- Fibromyalgie (4)
- Finite-Elemente-Methode (4)
- Fluorescence Microscopy (4)
- Fotokatalyse (4)
- Fotophysik (4)
- Fragmentation (4)
- G protein-coupled receptors (4)
- G proteins (4)
- G-Protein gekoppelter Rezeptor (4)
- GFAP (4)
- GVHD (4)
- Gasionisationsdetektor (4)
- Gelenkknorpel (4)
- Gene regulation (4)
- Geographie (4)
- Geoinformationssystem (4)
- Geschlecht (4)
- Geschlechtsbestimmung (4)
- Glucosetransportproteine (4)
- Governance (4)
- Graphene (4)
- Growth (4)
- GvHD (4)
- HPLC-MS (4)
- Hall, Stuart (4)
- Herzmuskel (4)
- Herzmuskelzelle (4)
- Heubacillus (4)
- Hierarchy (4)
- Higgs (4)
- Histone (4)
- Hyaluronsäure (4)
- Höhengradient (4)
- Image Processing (4)
- Immunisierung (4)
- Immunmodulation (4)
- Immunobiologie (4)
- Immunsuppression (4)
- Impfung (4)
- Implantat (4)
- Infrarotspektroskopie (4)
- Inhalation (4)
- Innate immunity (4)
- Innovation (4)
- Integrine (4)
- Internet (4)
- Internet of Things (4)
- Ionenkanal (4)
- Jura <Geologie> (4)
- Karoo (4)
- Kilimandscharo (4)
- Kind (4)
- Kommunikation (4)
- Korrelation (4)
- Krebsforschung (4)
- Kristallstruktur (4)
- Kristallwachstum (4)
- Kultur (4)
- Kutikularwachs (4)
- LEED (4)
- Langerhans cells (4)
- Laserspektroskopie (4)
- Leishmania major (4)
- Leishmaniose (4)
- Lepidoptera (4)
- Lernverhalten (4)
- Lewis acids (4)
- Lipide (4)
- Localization (4)
- Lung (4)
- Lung cancer (4)
- Längsschnittuntersuchung (4)
- MIZ1 (4)
- MMB (4)
- Magnetic Resonance Imaging (4)
- Magnetoelektronik (4)
- Magnetowiderstand (4)
- Makrophagen (4)
- Mathematisches Modell (4)
- Mechanismus (4)
- Medaka (4)
- Medien (4)
- Medienkompetenz (4)
- Mehrkriterielle Optimierung (4)
- Melanoma (4)
- Mensch-Maschine-Schnittstelle (4)
- Mergers and Acquisitions (4)
- Mesenchymzelle (4)
- Messenger-RNS (4)
- Metaanalyse (4)
- Metabolomics (4)
- Metakognition (4)
- Metalloproteinasen (4)
- Metallosupramolekulare Chemie (4)
- Metastase (4)
- Methylation (4)
- Mimik (4)
- Models (4)
- Monetary Policy (4)
- Monoschicht (4)
- Motorisches Lernen (4)
- Mouse (4)
- Multiple Sklerose (4)
- Multiproteinkomplex (4)
- Mutualismus (4)
- Myatrophische Lateralsklerose (4)
- Mycobacterium tuberculosis (4)
- Myelin (4)
- Myocardial infarction (4)
- NASH (4)
- NET (4)
- NEXAFS (4)
- NGS (4)
- NHC (4)
- NIR-Spektroskopie (4)
- NPY (4)
- NSSI (4)
- NaV1.9 (4)
- Nanooptik (4)
- Nanoparticles (4)
- Naturschutz (4)
- Naturstoff (4)
- Nestbau (4)
- Netzhaut (4)
- Neurogenese (4)
- Neurons (4)
- Neurophysiologie (4)
- Neurospora crassa (4)
- Neurotrophic factors (4)
- Nichtglatte Optimierung (4)
- Nickelverbindungen (4)
- Niger (4)
- Nitratreduktase (4)
- Optimization (4)
- Orientierung (4)
- Overlay-Netz (4)
- Oxidative stress (4)
- PALM (4)
- PDE (4)
- PER (4)
- PSMA-RADS (4)
- Palökologie (4)
- Parkinson (4)
- Parkinson disease (4)
- Pathway (4)
- Peptide (4)
- Peptidsynthese (4)
- Perception (4)
- Permeabilität (4)
- Perylenbisdicarboximide <Perylen-3,4:9,10-bis(dicarboximide)> (4)
- Perylene Bisimide (4)
- Phagozytose (4)
- Pharmazie (4)
- Pheromone (4)
- Phänologie (4)
- Plants (4)
- Plasmodium falciparum (4)
- Plasmon (4)
- Pollination (4)
- Pontryagin maximum principle (4)
- Porin (4)
- Posttranskriptionelle Regulation (4)
- Prescriptive Analytics (4)
- Primaten (4)
- Protonen-NMR-Spektroskopie (4)
- Psychiatrie (4)
- Pump-Probe-Technik (4)
- Punktwolke (4)
- QoE (4)
- Quadrocopter (4)
- Quantenfeldtheorie (4)
- Quantenspinsystem (4)
- Quantitative anatomy (4)
- RCT (4)
- RFID (4)
- RNA modification (4)
- RNA-Seq (4)
- RNAi (4)
- Rashba effect (4)
- Rashba-Effekt (4)
- Rastertunnelmikroskopie (4)
- Reaktionsmechanismus (4)
- Rechnungslegung (4)
- Regression (4)
- Regulatory T cells (4)
- Remote sensing (4)
- Renormierungsgruppe (4)
- Resistenz (4)
- Ressourcenmanagement (4)
- Rheumatoid arthritis (4)
- Ribosom (4)
- Risikoanalyse (4)
- Robotics (4)
- Roux-en-Y gastric bypass surgery (4)
- Ruthenium (4)
- Ruthenium complexes (4)
- Rutheniumkomplexe (4)
- Röntgendiffraktometrie (4)
- SAS <Programm> (4)
- SGLT1 (4)
- SQH method (4)
- STAT3 (4)
- Salmonella Typhimurium (4)
- Schwämme (4)
- Sekundärmetabolit (4)
- Selbst (4)
- Signal transduction (4)
- Silicium (4)
- Skin (4)
- Smad (4)
- Software Engineering (4)
- Sol-Gel-Verfahren (4)
- Solarzelle (4)
- Soziale Wahrnehmung (4)
- Spectroscopy (4)
- Stability (4)
- Staphylococcus (4)
- Stratigraphie (4)
- Streptomyces (4)
- Struktur (4)
- Supply Chain Management (4)
- Supraleiter (4)
- Supramolekulare Struktur (4)
- Surgery (4)
- Synapsine (4)
- Synthesis (4)
- T-lymphocytes (4)
- TFIIH (4)
- TGF-beta (4)
- TNF receptor superfamily (4)
- TRAF2 (4)
- Tansania (4)
- Targeted drug delivery (4)
- Telekommunikationsnetz (4)
- Temperatur (4)
- Th17 (4)
- Theoretische Physik (4)
- Theoretische Ökologie (4)
- Thrombozytenaggregation (4)
- Tiermodell (4)
- Transforming Growth Factor beta (4)
- Transgene Tiere (4)
- Transiente Absorption (4)
- Transpiration <Pflanzen> (4)
- Treg (4)
- Triarylamine (4)
- Triarylborane (4)
- USP28 (4)
- UV/Vis spectroscopy (4)
- Ubiquitinierung (4)
- Ultraschnelle Photochemie (4)
- Ultraviolett-Photoelektronenspektroskopie (4)
- Ungleichheit (4)
- Ureaplasma parvum (4)
- Vaccination (4)
- Validation (4)
- Verarbeitungsflüssigkeit (4)
- Virtualisierung (4)
- Wasseroxidation (4)
- Wide-gap-Halbleiter (4)
- Williams, Raymond (4)
- Wirkstofffreisetzung (4)
- Wirtschaftsinformatik (4)
- XML (4)
- XRD (4)
- Z boson (4)
- Zeitreihe (4)
- Zelladhäsion (4)
- Zink (4)
- Zoologie (4)
- accumulation (4)
- acid sphingomyelinase (4)
- action (4)
- active galactic nuclei (4)
- adenosine (4)
- affect (4)
- age-related macular degeneration (4)
- agency (4)
- aldosterone (4)
- alignment (4)
- amino acid (4)
- amyotrophic-lateral-sclerosis (4)
- anemia (4)
- animals (4)
- anorexia nervosa (4)
- antagonists (4)
- anticipation (4)
- anticoagulation (4)
- antifungals (4)
- antimicrobial (4)
- antimicrobial peptides (4)
- antiretroviral therapy (4)
- antisense RNA (4)
- apis mellifera (4)
- arrhythmia (4)
- arthritis (4)
- aspergillosis (4)
- aspergillus fumigatus (4)
- associative learning (4)
- athletes (4)
- atopic dermatitis (4)
- attention-deficit/hyperactivity disorder (ADHD) (4)
- autism (4)
- autoimmune disease (4)
- avatars (4)
- beta diversity (4)
- bevacizumab (4)
- binding analysis (4)
- biodiversity conservation (4)
- biofilms (4)
- biomass (4)
- biomechanics (4)
- birds (4)
- blood plasma (4)
- body composition (4)
- bone-mineral density (4)
- burden (4)
- calcium phosphate (4)
- cancer metabolism (4)
- cancer patients (4)
- capsaicin (4)
- carbohydrates (4)
- carcinomas (4)
- cardiac (4)
- cardiorespiratory fitness (4)
- cardiovascular (4)
- cardiovascular genetics (4)
- cardiovascular risk factors (4)
- care (4)
- cartilage regeneration (4)
- cell culture (4)
- cell-cycle arrest (4)
- cervical dystonia (4)
- chlamydia trachomatis (4)
- chondrogenic differentiation (4)
- cisplatin (4)
- clinical study (4)
- clinical trials (4)
- cochlear implant (4)
- collagen (4)
- colony-stimulating factor (4)
- combination therapy (4)
- computational chemistry (4)
- consciousness (4)
- consortium (4)
- correction (4)
- critical care (4)
- crosstalk (4)
- crowdsensing (4)
- culture (4)
- cytokine (4)
- deadwood enrichment (4)
- decellularization (4)
- decoherence (4)
- deficiency (4)
- degeneration (4)
- dehydrocoupling (4)
- democracy (4)
- dentate gyrus (4)
- dermatology (4)
- desmosomes (4)
- dexamethasone (4)
- diagnostic markers (4)
- diborane (4)
- diboranes (4)
- diborene (4)
- diffusion (4)
- disease severity (4)
- dyes/pigments (4)
- ecological intensification (4)
- economic growth (4)
- ecosystem function (4)
- ecosystem service (4)
- editorial (4)
- ejection fraction (4)
- elderly (4)
- electrochemistry (4)
- electron (4)
- electrospinning (4)
- endoscopy (4)
- endothelium (4)
- endurance training (4)
- entanglement (4)
- environment (4)
- enzyme (4)
- ethanol (4)
- exciton coupling (4)
- excitons (4)
- experimental stroke (4)
- fNIRS (4)
- face perception (4)
- fatty acids (4)
- feminism (4)
- ferroptosis (4)
- fish (4)
- fish model (4)
- fluorescence resonance energy transfer (4)
- fluorescent protein (4)
- fluoroarene (4)
- follow up (4)
- forensic neurotraumatology (4)
- fullerenes (4)
- functional characterization (4)
- functional diversity (4)
- fungal structure (4)
- gait initiation (4)
- games (4)
- gametogenesis (4)
- gas phase (4)
- genetic loci (4)
- genome annotation (4)
- genotype (4)
- geoarchaeology (4)
- geography (4)
- germinal center (4)
- giant cell arteritis (4)
- globalization (4)
- glucocorticoids (4)
- glucose transporter (4)
- glycolysis (4)
- gynecology (4)
- habitats (4)
- head (4)
- healthy volunteers (4)
- heat transfer (4)
- hematology (4)
- hematopoietic stem cells (4)
- hepatitis C virus (4)
- homologous recombination (4)
- hospitalization (4)
- host cells (4)
- humanized mice (4)
- hybrid materials (4)
- hydrodynamics (4)
- hydrogen bonding (4)
- hypercortisolism (4)
- hyperekplexia (4)
- iPSC (4)
- image processing (4)
- imaging techniques (4)
- immune checkpoint blockade (4)
- immunization (4)
- immunohistochemistry techniques (4)
- implant (4)
- impulsivity (4)
- in vitro model (4)
- individual-based model (4)
- induction (4)
- infectious diseases (4)
- information (4)
- inpatient rehabilitation (4)
- insect brain (4)
- insulin receptor (4)
- interoception (4)
- intervention (4)
- intestine (4)
- invasive aspergillosis (4)
- invasive pulmonary aspergillosis (4)
- ionic liquids (4)
- iron oxide nanoparticles (4)
- jet energy resolution (4)
- juvenile idiopathic arthritis (4)
- knee (4)
- land cover (4)
- language (4)
- learning curve (4)
- lines (4)
- linkage (4)
- lipid bilayer (4)
- living cells (4)
- locus coeruleus (4)
- macrocycles (4)
- magnesium phosphate cement (4)
- malignant melanoma (4)
- man-computer interface (4)
- marine sponge (4)
- matrix metalloproteinases (4)
- medical education (4)
- medical research (4)
- melatonin (4)
- memory B cells (4)
- meningioma (4)
- metabarcoding (4)
- metabolic adaptation (4)
- microRNAs (4)
- microarrays (4)
- micronuclei (4)
- mindfulness (4)
- minimally invasive surgery (4)
- modeling (4)
- modelling (4)
- modulation (4)
- molecular modeling (4)
- molecular modelling (4)
- monoclonal antibody (4)
- morphology (4)
- motility (4)
- multi-fluid mixture (4)
- multisensory processing (4)
- muscarinic receptors (4)
- muscle (4)
- music (4)
- myelination (4)
- naphthylisoquinoline alkaloids (4)
- natural enemies (4)
- neisseria meningitidis (4)
- nephrotoxicity (4)
- networks (4)
- neural stem cells (4)
- neurodevelopment (4)
- neuroimaging (4)
- neuroimmunology (4)
- neuromelanin (4)
- neurotrophic factor (4)
- neurotrophins (4)
- neutrophil (4)
- nickel (4)
- norepinephrine transporter (4)
- nucleolus (4)
- nucleus (4)
- oligodendrocytes (4)
- opioid receptors (4)
- opioids (4)
- organische Halbleiter (4)
- organoid (4)
- osteoblasts (4)
- oxidation (4)
- pancreas (4)
- parasitology (4)
- particle physics (4)
- pathogenicity (4)
- pathways (4)
- patient (4)
- patient blood management (4)
- performance monitoring (4)
- perioperative management (4)
- periprosthetic infection (4)
- persistence (4)
- personality (4)
- phagocytosis (4)
- pharmacogenetics (4)
- pheromone (4)
- phosphoantigen (4)
- phosphorescence (4)
- photodynamic therapy (4)
- photophysics (4)
- phylogenetic analysis (4)
- physiology (4)
- phytic acid (4)
- plasma cells (4)
- plasma membrane (4)
- plasmonics (4)
- pluripotency (4)
- pollution (4)
- polycycles (4)
- polygenic risk score (4)
- polymer (4)
- polymerase chain reaction (4)
- porin (4)
- post-traumatic stress disorder (4)
- potassium (4)
- principal component analysis (4)
- prognostic marker (4)
- prospective (4)
- protease inhibitors (4)
- protein expression (4)
- protein structure (4)
- protein synthesis (4)
- psychiatry (4)
- pulmonary embolism (4)
- punishment (4)
- quantum optics (4)
- radar (4)
- radioiodine therapy (4)
- rainforest (4)
- reaction time (4)
- reactive intermediates (4)
- rectal cancer (4)
- regeneration (4)
- religion (4)
- renal function (4)
- resin (4)
- response inhibition (4)
- revision (4)
- ribosomal RNA (4)
- ribosome biogenesis (4)
- ring-opening polymerization (4)
- risk assessment (4)
- risk factor (4)
- rotation (4)
- ruthenium complexes (4)
- saccades (4)
- saproxylic beetles (4)
- sarcopenia (4)
- scanning tunneling microscopy (4)
- schistosomiasis (4)
- seasonality (4)
- self (4)
- sensitivity (4)
- sensor (4)
- sequence motif analysis (4)
- sex (4)
- sex chromosomes (4)
- sexual selection (4)
- shape (4)
- silver (4)
- singlet oxygen (4)
- skin punch biopsy (4)
- smartwatch (4)
- social systems (4)
- spacer (4)
- specialization (4)
- specificity (4)
- sperm (4)
- sphingomyelinase (4)
- spider phobia (4)
- spiders (4)
- spillover (4)
- standardization (4)
- startle reflex (4)
- stem cell transplantation (4)
- streptomyces (4)
- streptozotocin (4)
- stromal cells (4)
- subarachnoid hemorrhage (4)
- substantia nigra (4)
- sulfur (4)
- super-resolution (4)
- surface water (4)
- surgical and invasive medical procedures (4)
- surgical oncology (4)
- surveillance (4)
- sustainability (4)
- synapses (4)
- systemic sclerosis (4)
- systems (4)
- teeth (4)
- telemedicine (4)
- thermoregulation (4)
- thiol-ene (4)
- thrombin (4)
- thrombopoiesis (4)
- thymus (4)
- tight junction (4)
- time series analysis (4)
- time-resolved spectroscopy (4)
- tissue (4)
- titanium (4)
- toe (4)
- tomato (4)
- top quark mass (4)
- topology (4)
- total knee replacement (4)
- transient absorption spectroscopy (4)
- transient ischemic attack (4)
- transposable elements (4)
- triarylamine (4)
- triarylborane (4)
- tryptophan (4)
- tuberculosis (4)
- tumor heterogeneity (4)
- tumour (4)
- two-dimensional materials (4)
- tyrosine kinase (4)
- ubiquitination (4)
- ultimatum game (4)
- ultrafast photochemistry (4)
- ultrasound (4)
- unconscious processing (4)
- uremic toxins (4)
- user experience (4)
- uveal melanoma (4)
- vesicles (4)
- viral infection (4)
- virotherapy (4)
- viruses (4)
- visual perception (4)
- vitamin C (4)
- well-being (4)
- wound healing (4)
- zinc oxide nanoparticles (4)
- Übergangsmetalloxide (4)
- γ-H2AX (4)
- 18F-DCFPyL (3)
- 18F-FDG PET/CT (3)
- 18F-LMI1195 (3)
- 3D models (3)
- 3D reconstruction (3)
- 5-HT1A (3)
- 5-HT2C (3)
- 5-Methylcytosine (3)
- A-priori-Wissen (3)
- ABA (3)
- AFM (3)
- AML (3)
- ARIA (3)
- Abscisinsäure (3)
- Abwehr (3)
- Abwehrreaktion (3)
- Actinomycetes (3)
- AdS/CFT correspondence (3)
- Adaptive Optics (3)
- Adaptive Optik (3)
- Adenosin (3)
- Adjuvans (3)
- Adsorption (3)
- Advanced Analytics (3)
- Afrika (3)
- Agonist (3)
- Aktivierung <Physiologie> (3)
- Algorithmische Geometrie (3)
- Alkaloide (3)
- Allergy (3)
- Alltagskultur (3)
- Alpen (3)
- Altern (3)
- Ameise (3)
- Amphibian oocytes (3)
- Amygdala (3)
- Angeborene Immunität (3)
- Animal model (3)
- Annotation (3)
- Anthropocene (3)
- Antizipation (3)
- Aorta (3)
- Araneae (3)
- Arctic (3)
- Arzneimittelforschung (3)
- Assoziation (3)
- Atherosklerose (3)
- Atta vollenweideri (3)
- Autoaggressionskrankheit (3)
- Automation (3)
- Autonomous UAV (3)
- Außenhandel (3)
- Avatar <Informatik> (3)
- Axon (3)
- B-lymphocytes (3)
- BL-Lacertae-Objekt (3)
- BN compounds (3)
- BRAF mutation (3)
- Bayesian classifier (3)
- Begabung (3)
- Behaviour (3)
- Benchmarking (3)
- Berechnungskomplexität (3)
- Beschichtung (3)
- Big Data (3)
- Biokinetics (3)
- Biologischer Abbau (3)
- Biomarkers (3)
- Biomedical engineering (3)
- Biomedicine (3)
- Bioreaktor (3)
- Biosensor (3)
- Bipolar disorder (3)
- Biradicals (3)
- Biradikal (3)
- Blimp-1 (3)
- Blutstillung (3)
- Boden (3)
- Bone marrow transplantation (3)
- Borneo (3)
- Borrelia (3)
- Bosons (3)
- Brain-computer interface (3)
- Bronchialasthma (3)
- C. elegans (3)
- C5aR1 (3)
- CAR T cell (3)
- CAR T cells (3)
- CD39 (3)
- CD4(+) (3)
- CD40 (3)
- CD73 (3)
- CD8 (3)
- CDH13 (3)
- CIDP (3)
- CNTF (3)
- COVID-19 pandemic (3)
- COVID‐19 (3)
- CRMO (3)
- Calciumphosphate (3)
- Carbene (3)
- Carcinogenese (3)
- Carcinogenesis (3)
- Carcinogenicity (3)
- Carcinogens (3)
- CdTe (3)
- Cells (3)
- Central Asia (3)
- Central nervous system (3)
- Cerebellar cortex (3)
- Channelrhodopsin (3)
- Charged Aerosol Detection (3)
- Chemische Kommunikation (3)
- Chemotaxis (3)
- Chirality (3)
- Chiralität (3)
- Ciliary neurotrophic factor (3)
- Circadian Rhythms (3)
- Circular dichroism (3)
- Climate Change (3)
- Coexpression (3)
- Cognition (3)
- Coleoptera (3)
- Complexity (3)
- Computer Vision (3)
- Copula (3)
- Cyanobacteria (3)
- Cyclo-AMP (3)
- Cycloaddition (3)
- Cystein (3)
- Cystic fibrosis (3)
- Cytomegalie-Virus (3)
- DNA double-strand breaks (3)
- DNA replication (3)
- DNA-Schaden (3)
- DUB (3)
- DaTscan (3)
- Darm (3)
- Darmflora (3)
- Data Fusion (3)
- Datenanalyse (3)
- Dauerfrostboden (3)
- Deformation (3)
- Degradation (3)
- Deoxyribozymes (3)
- Devisenmarkt (3)
- Diagnostik (3)
- Dickdarmkrebs (3)
- Differentialgeometrie (3)
- Differentiation (3)
- Differenzierung (3)
- Digital Humanities (3)
- Digitalisierung (3)
- Dimere (3)
- Dimerisierung (3)
- Dionaea muscipula (3)
- Distributed Control (3)
- Diversität (3)
- Drahtloses lokales Netz (3)
- Dreidimensionale Rekonstruktion (3)
- Drug resistance (3)
- Drugs (3)
- Duplikation (3)
- Dynamisches System (3)
- EBV (3)
- EPR spectroscopy (3)
- ESS (3)
- Echtzeit (3)
- Echtzeitsystem (3)
- Egypt (3)
- Eiablage (3)
- Eierstockkrebs (3)
- Einkommensverteilung (3)
- Einwandige Kohlenstoff-Nanoröhre (3)
- Electroencephalographie (3)
- Electrophysiology (3)
- Elektronenmikroskopie (3)
- Elektrospinnen (3)
- Elliptische Differentialgleichung (3)
- Embryo (3)
- Endosymbiont (3)
- Endothelium (3)
- Endothelzelle (3)
- Energieeffizienz (3)
- Energietransfer (3)
- Energy Efficiency (3)
- Energy Transfer (3)
- Entscheidung (3)
- Entscheidungsunterstützungssystem (3)
- Enzyme induction (3)
- Enzymes (3)
- Epichloë (3)
- Epitaxie (3)
- Ereigniskorreliertes Potenzial (3)
- Erratum (3)
- European beech (3)
- Events (3)
- Exciton (3)
- Expansion microscopy (3)
- Expositionstherapie (3)
- FGF (3)
- FMRI (3)
- Fabry (3)
- Fabry-Krankheit (3)
- Fabry-associated pain (3)
- Fahrerassistenzsystem (3)
- Fahrerverhalten (3)
- Fanconi Anemia (3)
- Femtochemie (3)
- Ferromagnetic Semiconductors (3)
- Fettgewebe (3)
- Fettsucht (3)
- Fettsäurebiosynthese (3)
- Fettsäurestoffwechsel (3)
- Fettzelle (3)
- Fibroblasts (3)
- Fibromyalgia syndrome (3)
- Finite-Volumen-Methode (3)
- Fische (3)
- Flavour <Elementarteilchen> (3)
- Fluorescence spectroscopy (3)
- Fokker-Planck-Gleichung (3)
- Forecasting (3)
- Formulierungsentwicklung (3)
- Fortpflanzungsverhalten (3)
- Fotochemie (3)
- Fotoionisation (3)
- Foxp3 (3)
- Fragmentierung (3)
- Frequenzvervielfachung (3)
- Frosch (3)
- G-Protein gekoppelte Rezeptor (3)
- G-protein-coupled receptors (3)
- GAS2L3 (3)
- Galerkin-Methode (3)
- Gallium (3)
- Gasgemisch (3)
- Gauge-gravity correspondence (3)
- Gaussian approximation (3)
- Gedächtnisbildung (3)
- Gedächtnisleistung (3)
- Gefäßpflanzen (3)
- Gelernte Hilflosigkeit (3)
- Genome (3)
- Genomics (3)
- Geologie (3)
- Geophysik (3)
- Germanium (3)
- Gerste (3)
- Geschmack (3)
- Gesicht (3)
- Gewebe (3)
- Gibbs free energy of binding (3)
- Gletscher (3)
- Glioblastom (3)
- Glutathione (3)
- Glycinrezeptor (3)
- Glykosylierung (3)
- Golgi (3)
- Grad-seq (3)
- Graft-versus-host disease (3)
- Gram-positive bacteria (3)
- Grenzfläche (3)
- Grundwasser (3)
- HBMEC (3)
- HFpEF (3)
- HIV-1 (3)
- Hadron Colliders (3)
- Halbleiterphysik (3)
- Halbleiterschicht (3)
- Hautflügler (3)
- Hautkrebs (3)
- Hearing loss (3)
- Helicasen (3)
- Herbivory (3)
- Herzinsuffizienz (3)
- Heterocyclische Carbene <-N> (3)
- Heteroepitaxie (3)
- Hill numbers (3)
- Hirnhautentzündung (3)
- Hirschsprung disease (3)
- Hitzeschock-Proteine (3)
- Hochtemperatursupraleitung (3)
- Hodgkin lymphoma (3)
- Hsp90 (3)
- Humangenetik (3)
- Humans (3)
- Hummel (3)
- Hummeln (3)
- Hyaliner Knorpel (3)
- Hydrodynamik (3)
- IGF-I (3)
- IGRT (3)
- Ideomotorik (3)
- IgE (3)
- Imaging (3)
- Impfstoff (3)
- In-vitro (3)
- In-vitro-Kultur (3)
- Industrie 4.0 (3)
- Influenza (3)
- Information (3)
- Information Extraction (3)
- Insects (3)
- Interkulturelles Lernen (3)
- Interleukin 6 (3)
- Interleukin-5 (3)
- Internationalität (3)
- Internet der Dinge (3)
- Ionic Liquids (3)
- Irradiation (3)
- Ischemia (3)
- Ischemic stroke (3)
- JNK (3)
- Jura (3)
- Jurassic (3)
- Kardiologie (3)
- Kation (3)
- Kenyon cells (3)
- Kinasen (3)
- Kinetik (3)
- Klassische Konditionierung (3)
- Knochenzement (3)
- Knockout (3)
- Knorpel (3)
- Kognitive Entwicklung (3)
- Kohlenmonoxid (3)
- Kohlenstoff (3)
- Kohlenstoff-Nanoröhre (3)
- Kohlenwasserstoffe (3)
- Kohärente Kontrolle (3)
- Kombinatorik (3)
- Konfidenzintervall (3)
- Kontrollierte Wirkstofffreisetzung (3)
- Kontrolltheorie (3)
- Kulturtheorie (3)
- LC-HRESIMS (3)
- LC/MS (3)
- LINC complex (3)
- Ladungstransport (3)
- Larve (3)
- Latenz (3)
- Learning and memory (3)
- Lebendgebärende Zahnkarpfen (3)
- Leber (3)
- Lepton (3)
- LiDAR (3)
- Lidschlag (3)
- Ljapunov-Funktion (3)
- LoRaWAN (3)
- Lokalisation (3)
- Lolium perenne (3)
- Luminescence (3)
- Lumineszenz (3)
- Lunge (3)
- Lurche (3)
- Luttinger-Flüssigkeit (3)
- MAP kinase (3)
- MC simulation (3)
- MDD (3)
- MDSC (3)
- MIBG (3)
- MPEC (3)
- MRT (3)
- MSCs (3)
- MSSM (3)
- Macaranga (3)
- Macrophages (3)
- Magnetic Anisotropy (3)
- Magnetoelastizität (3)
- Malignant melanoma (3)
- Management (3)
- Mangan (3)
- Mangansilicide (3)
- Masernvirus (3)
- Mc4r (3)
- Measurement (3)
- Measuring Masses (3)
- Megakaryocyte (3)
- Mehragentensystem (3)
- Melt Electrowriting (3)
- Melt electrowriting (3)
- Membranproteine (3)
- Merkel cell polyomavirus (3)
- Merocyanin (3)
- Mesoskopisches System (3)
- Messung (3)
- Methyltransferase (3)
- Mexiko (3)
- Microglia (3)
- Migration (3)
- Mikroklima (3)
- Mikrotubuli (3)
- Mikrotubulus (3)
- Mixed Reality (3)
- Modelling (3)
- Molecular Beam Epitaxy (3)
- Molecular dynamics (3)
- Molekularbewegung (3)
- Molekulare Bildgebung (3)
- Molekulare Erkennung (3)
- Monodromie (3)
- Monte Carlo simulation (3)
- Mortality (3)
- Multiple Myeloma (3)
- Multiple bonds (3)
- Muscarinic receptor subtypes (3)
- Muscarinic receptors (3)
- Muskelzelle (3)
- Muster (3)
- Mutation (3)
- Mycobacterium (3)
- Myelin oligodendrocyte glycoprotein antibodies (MOG-IgG) (3)
- Myeloma (3)
- Myokarditis (3)
- N170 (3)
- NF-κB (3)
- NSG (3)
- Nanometerbereich (3)
- Nanoröhre (3)
- Natriumkanal (3)
- Neisseria (3)
- Nephroblastom (3)
- Nervennetz (3)
- Networks (3)
- Netzwerkanalyse (3)
- Netzwerkmanagement (3)
- Neuroblastom (3)
- Neuroinflammation (3)
- Neurologie (3)
- Neuromyelitis optica spectrum disorders (NMOSD) (3)
- Neuropathie (3)
- Neuropathy (3)
- Neuroprotection (3)
- Neuroscience (3)
- Neurowissenschaften (3)
- Neutrophil (3)
- Neutrophiler Granulozyt (3)
- Neutrophils (3)
- New Zealand (3)
- Nicht-kleinzelliges Bronchialkarzinom (3)
- Nichtkonvexe Optimierung (3)
- Nichtlineares System (3)
- Niere (3)
- Nonlinear Dynamics (3)
- Notenbank (3)
- Nrf2 (3)
- Nude-mice (3)
- Numerische Strömungssimulation (3)
- Oberflächenplasmonresonanz (3)
- Oberflächenzustand (3)
- Obesity (3)
- Olfaktorik (3)
- Oligomere (3)
- Omp85 (3)
- Oncology (3)
- Opiatrezeptor (3)
- Optic neuritis (3)
- Optical spectroscopy (3)
- Organisation (3)
- Organischer Feldeffekttransistor (3)
- Organoid (3)
- Ormocer (3)
- Outcome survey (3)
- Oxidation (3)
- Oxygen (3)
- P-glycoprotein (3)
- PI3K (3)
- PKA (3)
- PTCDA (3)
- PTEN (3)
- Pair Production (3)
- Pakistan (3)
- Parallele Bildgebung (3)
- Pareto-Verteilung (3)
- Parkinsons disease (3)
- Particle Physics (3)
- Particle data analysis (3)
- Partielle Differentialgleichung (3)
- Pathogens (3)
- Peer-to-Peer-Netz (3)
- Permafrost (3)
- Pharmaceutical Analysis (3)
- Phasenumwandlung (3)
- Phenomenology (3)
- Phospholipide (3)
- Phosphorylation (3)
- Phosphorylierung (3)
- Photoluminescence (3)
- Photosensibilisator (3)
- Physical activity (3)
- Physik jenseits des Standardmodells (3)
- Placebo (3)
- Plasma (3)
- Plasmamembran (3)
- Pluripotenz (3)
- Plättchen (3)
- Pneumolysin (3)
- Polycyclic Aromatic Hydrocarbons (3)
- Polycyclische Aromaten (3)
- Polyethylenglykole (3)
- Polymerase chain reaction (3)
- Polymers (3)
- Polymorphismus (3)
- Positron Emission Tomography (3)
- Positron emission tomography (3)
- Promoter (3)
- Prostaglandine (3)
- Prostate Cancer (3)
- Proteasen (3)
- Protein p53 (3)
- Protein-Tyrosin-Kinasen (3)
- Proteinbindung (3)
- Proteinkinase D (3)
- Proteinkinasen (3)
- Proton-Proton Collisions (3)
- Pseudomonas syringae (3)
- Pyrene (3)
- Pädagogik (3)
- QCD (3)
- Quadrotor (3)
- Quantendynamik (3)
- Quantenkontrolle (3)
- Quantenmechanik (3)
- Quantenwell (3)
- Quantifizierung (3)
- Quantum Monte Carlo (3)
- Quantum information (3)
- Quantum many-body systems (3)
- RIXS (3)
- RNA splicing (3)
- RNA structure (3)
- RNA-SEQ (3)
- RNA-sequencing (3)
- RNAseq (3)
- RNS-Bindungsproteine (3)
- RNS-Interferenz (3)
- RNS-Viren (3)
- RS1 (3)
- RSK (3)
- Rac1 (3)
- Radarsat-2 (3)
- Radikal <Chemie> (3)
- Radiosurgery (3)
- Raf (3)
- Raf-Kinasen (3)
- Raman Spektroskopie (3)
- Raman spectroscopy (3)
- Rats (3)
- Reaktive Sauerstoffspezies (3)
- Reduction (3)
- Regelung (3)
- Regenerative Medizin (3)
- Regulierung (3)
- Rekonstruktion (3)
- Relapse (3)
- Resilienz (3)
- Resonanz-Tunneleffekt (3)
- Retinoic acid (3)
- Risk (3)
- Risk Assessment (3)
- Roman (3)
- Ruthenium Komplexe (3)
- Röntgenastronomie (3)
- Röntgenbeugung (3)
- Röntgenkristallographie (3)
- Röntgenstrahlung (3)
- SEM (3)
- SLC2A3 (3)
- SM background (3)
- SMARD1 (3)
- SOAT1 (3)
- SOCE (3)
- SPECT/CT (3)
- SWOT (3)
- Sammeln (3)
- Sap47 (3)
- Savanne (3)
- Scarabaeidae (3)
- Scattering (3)
- Schizophrenia (3)
- Schmerz (3)
- Schmerzforschung (3)
- Schreiben (3)
- Schulleistung (3)
- Schwann cells (3)
- Search (3)
- Secretion (3)
- Sedimentologie (3)
- Selbstassemblierung (3)
- Selbstgesteuertes Lernen (3)
- Self-Assembly (3)
- Sensor (3)
- Sex determination (3)
- Signalkette (3)
- Silber (3)
- Sinnesphysiologie (3)
- Skorpion (3)
- Small nuclear RNP (3)
- SnRK1 (3)
- Social Cognition (3)
- Social Media (3)
- Software-defined networking (3)
- Softwarearchitektur (3)
- Solubilisation (3)
- Sozialangst (3)
- Species richness (3)
- Speckle tracking (3)
- Spermatogenesis (3)
- Sphingolipide (3)
- Spieltheorie (3)
- Spin flip (3)
- Splicing (3)
- Spred Protein (3)
- Staat (3)
- Stachellose Biene (3)
- Statistik (3)
- Stem cells (3)
- Sternpolymere (3)
- Stickstoff (3)
- Stickstoffmonoxid (3)
- Strahlungstransport (3)
- Strain (3)
- Strategisches Management (3)
- Streptococcus pneumoniae (3)
- Strukturanalyse (3)
- Strukturaufklärung (3)
- Super-resolution microscopy (3)
- Supersymmetric models (3)
- Surface plasmons (3)
- Symmetrie (3)
- Symmetry (3)
- Synapsin (3)
- Systematik (3)
- T cell receptors (3)
- T lymphocyte (3)
- T-Lymphozyten (3)
- T-Lymphozyten-Rezeptor (3)
- T-cell (3)
- TCR (3)
- TD-DFT (3)
- TEM (3)
- TGN1412 (3)
- TKI (3)
- TNF-alpha (3)
- TNFR1 (3)
- TP53 (3)
- TRH (3)
- Tabak (3)
- Taxonomie (3)
- Textvergleich (3)
- Theory of Mind (3)
- Thermodynamik (3)
- Thermoelektrizität (3)
- Thermoregulation (3)
- Thrombus (3)
- Thyroid cancer (3)
- Tierökologie (3)
- Toleranz (3)
- Toll-like-Rezeptoren (3)
- Tomate (3)
- Topological Insulator (3)
- Topological insulators (3)
- Topologische Phase (3)
- Topology (3)
- Tourette syndrome (3)
- Tourismus (3)
- Transgenic mice (3)
- Transkriptom (3)
- Transplantation (3)
- Transportprozess (3)
- Transposon (3)
- Trypanosomes (3)
- Tuberculosis (3)
- Tuberkulose (3)
- Tuff (3)
- Tumor-necrosis-factor (3)
- Typ 1 (3)
- Umweltfaktor (3)
- Ureaplasma urealyticum (3)
- VMAT (3)
- Vaccinia Virus (3)
- Vakuole (3)
- Variants (3)
- Variationsrechnung (3)
- Verkehrspsychologie (3)
- Verunreinigung (3)
- Video Streaming (3)
- Videoübertragung (3)
- Vietnam (3)
- Visuelles System (3)
- Vulkanologie (3)
- W boson (3)
- WNT (3)
- Wachstum (3)
- Wald (3)
- Warnung (3)
- Wasser (3)
- Wasserhaushalt (3)
- Weak (3)
- Wespen (3)
- Wilms' tumor (3)
- Wirkstoff-Träger-System (3)
- Wirt (3)
- Wirtschaftsprüfung (3)
- Wirtszelle (3)
- Wissen (3)
- Wissensmanagement (3)
- Wissensrepräsentation (3)
- Wolfram (3)
- Wundheilung (3)
- Währungsunion (3)
- Y chromosome (3)
- YAP (3)
- Zelllinie (3)
- Zentralasien (3)
- Zetafunktion (3)
- Zinkselenid (3)
- ab initio calculations (3)
- abandonment (3)
- abiotic stress (3)
- abnormalities (3)
- absolute configuration (3)
- accelerometer (3)
- acetylcholine (3)
- acrophobia (3)
- actins (3)
- action potential (3)
- acute respiratory distress syndrome (3)
- adaption (3)
- adaptive immune system (3)
- adaptive immunity (3)
- adenocarcinoma of the lung (3)
- adipose (3)
- adipose-derived stromal cells (3)
- adrenal (3)
- adrenal insufficiency (3)
- adrenocortical cancer (3)
- adverse events (3)
- aerobic fitness (3)
- affinity (3)
- african trypanosomes (3)
- age groups (3)
- agonist (3)
- agroecology (3)
- alcohol (3)
- alkaline phosphatase (3)
- alpha-synuclein (3)
- alternative splicing (3)
- altitudinal gradients (3)
- amyloidosis (3)
- anaemia (3)
- anastomotic leakage (3)
- aneurysm (3)
- angiography (3)
- animal sociality (3)
- ankle (3)
- antagonist (3)
- anterior insula (3)
- anthocyanins (3)
- antibacterial (3)
- antibiotic (3)
- anticoagulants (3)
- antigen testing (3)
- antimony (3)
- antioxidants (3)
- applied physics (3)
- approach (3)
- approximation algorithm (3)
- architecture (3)
- arctic (3)
- arrhythmogenic cardiomyopathy (3)
- arthrography (3)
- arthropods (3)
- artificial photosynthesis (3)
- assistive technology (3)
- attention deficit/hyperactivity disorder (3)
- auditory pathway (3)
- autoantigen (3)
- auxin (3)
- axonal damage (3)
- axons (3)
- azobenzenes (3)
- bacillus subtilis (3)
- back pain (3)
- bacterial infection (3)
- bacterial meningitis (3)
- bark beetles (3)
- bee decline (3)
- behaviour (3)
- beta-D-glucan (3)
- bilingualism (3)
- binding protein (3)
- bioactivity (3)
- biochemistry (3)
- bioconjugation (3)
- biogenic amines (3)
- biological models (3)
- biological pest control (3)
- biologics (3)
- bioluminescence imaging (3)
- biomedical engineering (3)
- biomedical materials (3)
- biopsy (3)
- biosensors (3)
- birth cohort (3)
- black holes (3)
- bladder cancer (3)
- blood vessel (3)
- bond activation (3)
- bone cement (3)
- bone disease (3)
- bone morphogenetic proteins (3)
- bone-marrow (3)
- boronate (3)
- borylenes (3)
- brain cancer (3)
- breast-tumors (3)
- bumblebees (3)
- burn severity (3)
- butterflies (3)
- c-Fos (3)
- c-Myc (3)
- c-myc (3)
- calcification (3)
- calcium phosphate cement (3)
- cancer cells (3)
- cancer immunotherapy (3)
- canine cancer therapy (3)
- canola (3)
- capillary electrophoresis (3)
- carbene ligands (3)
- cardiac magnetic resonance imaging (3)
- cardiac metabolism (3)
- cardiolipin (3)
- cardiovascular magnetic resonance (3)
- caspase-3 (3)
- cationic species (3)
- cations (3)
- cell (3)
- cell binding (3)
- cell fusion (3)
- cell imaging (3)
- cell labeling (3)
- cell therapy (3)
- central-nervous-system (3)
- cerebellar tDCS (3)
- cerebrovascular disorders (3)
- chalcogens (3)
- channelrhodopsin (3)
- chaperone (3)
- charge separation (3)
- charged aerosol detector (3)
- chemische Kommunikation (3)
- chimeric antigen receptor (3)
- chlamydia infection (3)
- chondrogenesis (3)
- chromophore (3)
- chronic stress (3)
- citrus (3)
- clinical practice (3)
- cloning (3)
- closed head injury (3)
- cochlea (3)
- cochlear implantation (3)
- coexistence (3)
- cohort studies (3)
- colonoscopy (3)
- comet assay (3)
- community (3)
- community ecology (3)
- complement (3)
- complications (3)
- conditioned response (3)
- conjugation (3)
- context (3)
- conversion (3)
- convolutional neural network (3)
- convolutional neural networks (3)
- cooperation (3)
- copy number variation (3)
- coronavirus (3)
- corticosteroids (3)
- count time series (3)
- criteria (3)
- critically ill (3)
- crossing minimization (3)
- crowdsourcing (3)
- cryptochrome (3)
- crystallography (3)
- cycloaddition (3)
- cysteine protease (3)
- cytosol (3)
- data acquisition (3)
- data fusion (3)
- deafness (3)
- death receptors (3)
- decomposition (3)
- defects (3)
- deficient mice (3)
- definition (3)
- deformation (3)
- deformation quantization (3)
- density (3)
- deoxyribozymes (3)
- derivatives (3)
- desmin (3)
- detrended fluctuation analysis (3)
- developmental differentiation (3)
- diabetic nephropathy (3)
- diagnostic medicine (3)
- diazepam (3)
- diboration (3)
- dilated cardiomyopathy (3)
- dimerization (3)
- discourse analysis (3)
- disease progression (3)
- diseases (3)
- disorder (3)
- distribution (3)
- diversity gradients (3)
- docking (3)
- doctoral graduates (3)
- dogs (3)
- double-blind (3)
- drosophila (3)
- drug adverse reaction (3)
- drug allergy (3)
- drug development (3)
- drug hypersensitivity (3)
- drug metabolism (3)
- drug resistance (3)
- drug therapy (3)
- drugs (3)
- dynamic programming (3)
- eating behavior (3)
- efficiency (3)
- electrical and electronic engineering (3)
- electrocardiography (3)
- electroencephalogram (3)
- electrohydrodynamic (3)
- electrohydrodynamics (3)
- electron density (3)
- electron tomography (3)
- electron transfer (3)
- elevated plus-maze (3)
- elevation (3)
- elevational gradient (3)
- embodied cognition (3)
- embryonic stem cells (3)
- embryos (3)
- emotion processing (3)
- emotional regulation (3)
- emphysema (3)
- end-stage renal disease (3)
- endophyte (3)
- endoradiotherapy (3)
- endovascular (3)
- endurance exercise (3)
- engineering (3)
- entomology (3)
- entropy (3)
- entropy production (3)
- environmental health (3)
- epidermis (3)
- essential genes (3)
- essential tremor (3)
- estrogen receptor (3)
- estrogens (3)
- evidence-based medicine (3)
- excited states (3)
- exciton dynamics (3)
- exercise intensity (3)
- exome sequencing (3)
- exosomes (3)
- exposure therapy (3)
- extracorporeal membrane oxygenation (3)
- extreme value theory (3)
- eye-tracking (3)
- face (3)
- face processing (3)
- fatty liver disease (3)
- feedback (3)
- feeding (3)
- female (3)
- fertility (3)
- fibrin (3)
- fibroblasts (3)
- fitness (3)
- flagella (3)
- flagellum (3)
- flowers (3)
- fluorescence spectroscopy (3)
- flux (3)
- force (3)
- forest ecology (3)
- formicidae (3)
- fragmentation (3)
- frailty (3)
- frontotemporal dementia (3)
- fully convolutional neural networks (3)
- functional training (3)
- fungal pathogens (3)
- fungal rhodopsins (3)
- fusion (3)
- gait analysis (3)
- gametocyte (3)
- gamma radiation (3)
- gamma rays (3)
- gastroenterology (3)
- gefitinib (3)
- gender differences (3)
- gene targeting (3)
- gene therapy (3)
- genetic modifiers (3)
- genetic variation (3)
- genome assembly (3)
- genome integrity (3)
- genome sequence (3)
- genomic damage (3)
- genotyping (3)
- gingivitis (3)
- glaciers (3)
- glial fibrillary acidic protein (3)
- glomerular filtration rate (3)
- glomeruli (3)
- glutamate (3)
- graphene (3)
- growth cone (3)
- growth factor (3)
- guard cell (3)
- haemostasis (3)
- hands (3)
- healing (3)
- healthcare (3)
- hearing (3)
- helminths (3)
- hemoglobin (3)
- hemolysin (3)
- hepatitis B virus (3)
- herbivores (3)
- herbivory (3)
- heritability (3)
- herpesvirus (3)
- hiPSC-CM (3)
- high-intensity interval training (3)
- hip (3)
- histone H2AX (3)
- histones (3)
- historical document analysis (3)
- homology modeling (3)
- honeycomb lattice (3)
- host-pathogen interactions (3)
- human brain (3)
- human immunodeficiency virus (3)
- human learning (3)
- humidity (3)
- hydrology (3)
- hypertrophic cardiomyopathy (3)
- hypofractionation (3)
- image segmentation (3)
- immediate early genes (3)
- immersive technologies (3)
- immune escape (3)
- immunoreactive neurons (3)
- immunosenescence (3)
- impedance spectroscopy (3)
- impurity profiling (3)
- incisional hernia (3)
- indication for surgery (3)
- individual differences (3)
- individual-based simulation (3)
- infections (3)
- inflammatory diseases (3)
- inflammatory pain (3)
- influenza A virus (3)
- information extraction (3)
- inhibitors (3)
- innate immune response (3)
- innovation (3)
- instrument (3)
- insulator (3)
- integration (3)
- intelligence (3)
- intensity distribution (3)
- intensive care (3)
- intentional binding (3)
- interaction networks (3)
- interactome (3)
- interface (3)
- interferon (3)
- interleukin-6 (3)
- interleukins (3)
- interview (3)
- intestinal epithelial barrier (3)
- intuition (3)
- inventory (3)
- investigators (3)
- involvement (3)
- ion channel (3)
- ion channels (3)
- iron deficiency (3)
- irradiation (3)
- irrigation (3)
- islets of Langerhans (3)
- isotopes (3)
- jet energy scale uncertainty (3)
- jets (3)
- juvenile hormone (3)
- ketogenic diet (3)
- kidney function (3)
- kinase inhibitor (3)
- kinematics (3)
- kinesin (3)
- kinetic model (3)
- knee arthroplasty (3)
- kutikuläre Kohlenwasserstoffe (3)
- land-use change (3)
- landscape ecology (3)
- laparoscopic ventral hernia repair (3)
- laser (3)
- leaf beetle (3)
- leaves (3)
- left ventricular hypertrophy (3)
- leishmania major (3)
- lenalidomide (3)
- length of stenosis (3)
- leukemic cells (3)
- leukocytes (3)
- library screening (3)
- life history (3)
- ligand binding (3)
- ligands (3)
- light quark jet (3)
- lipid rafts (3)
- lipidomics (3)
- liquid crystals (3)
- liraglutide (3)
- lithium (3)
- liver metastasis (3)
- local field potentials (3)
- locomotor activity (3)
- loneliness (3)
- low back pain (3)
- low-valent compounds (3)
- lung and intrathoracic tumors (3)
- lung fibrosis (3)
- lung injury (3)
- mTOR (3)
- magnetic properties and materials (3)
- magnetic resonance (3)
- main group elements (3)
- major depressive disorder (3)
- major histocompatibility complex (3)
- malignancy (3)
- malignant tumors (3)
- marine natural products (3)
- mass (3)
- mastocytosis (3)
- mathematical modelling (3)
- mathematics (3)
- matrix metalloproteinase (3)
- maturation (3)
- measles (3)
- measurement (3)
- mechanics (3)
- mechanosensing (3)
- media literacy (3)
- medical rehabilitation (3)
- megakaryopoiesis (3)
- melanogaster (3)
- melt electrowriting (MEW) (3)
- memory formation (3)
- merocyanines (3)
- mesencephalic locomotor region (3)
- mesenchymal stromal cells (3)
- mesoscopics (3)
- messenger-RNA (3)
- metabolic modeling (3)
- metabolites (3)
- metacognition (3)
- metacomprehension (3)
- metallosupramolecular chemistry (3)
- methionine restriction (3)
- miR-21 (3)
- miRNAs (3)
- micelles (3)
- microbial ecology (3)
- microbial rhodopsins (3)
- microclimate (3)
- microvascular endothelial cells (3)
- migraine (3)
- mimicry (3)
- minimally invasive (3)
- mitotane (3)
- mixed methods (3)
- mobile health (3)
- molecular phylogeny (3)
- monocyte (3)
- monoklonale Antikörper (3)
- morality (3)
- morbidity (3)
- morphometry (3)
- mothers (3)
- motor learning (3)
- multi-unit recording (3)
- multijet background (3)
- multilocularis (3)
- multiple bonds (3)
- multiple linear regression (3)
- multiple system atrophy (3)
- multisensory integration (3)
- murine (3)
- muscarinic receptor subtypes (3)
- muscle strength (3)
- myocardium (3)
- myofibroblast (3)
- n-Halbleiter (3)
- national park (3)
- national parks (3)
- natural history (3)
- natural language processing (3)
- natural variation (3)
- necroptosis (3)
- necrosis-factor-alpha (3)
- negative affect (3)
- nephroblastoma (3)
- nerve fibers (3)
- nest climate (3)
- network analysis (3)
- networking (3)
- neural crest (3)
- neurofilament light chain (3)
- neurological disorders (3)
- neuromodulation (3)
- neuronal network (3)
- neuropathology (3)
- neuropsychology (3)
- next-generation sequencing (3)
- niche (3)
- non-covalent interactions (3)
- non-prompt lepton (3)
- non-verbal communication (3)
- nonsmooth optimization (3)
- noradrenaline (3)
- nucleotide excision repair (3)
- numerical cognition (3)
- obstructive pulmonary disease (3)
- olfactory learning (3)
- olfactory memory (3)
- oligomerization (3)
- oncolytic viruses (3)
- onkolytische Virotherapie (3)
- ontology (3)
- open abdomen (3)
- operant conditioning (3)
- oral anticancer drugs (3)
- organic (3)
- organic light emitting diodes (3)
- organic molecule (3)
- organic photodiodes (3)
- organic photovoltaics (3)
- organic semiconductor (3)
- organic solar cell (3)
- organische Photovoltaik (3)
- organische Solarzelle (3)
- orientation (3)
- oscillation (3)
- oscillations (3)
- osteogenesis (3)
- osteogenic differentiation (3)
- outbreak (3)
- output elasticities (3)
- oxygen/glucose deprivation (3)
- oxygenation (3)
- paleoecology (3)
- parasite (3)
- pasture (3)
- patch-clamp (3)
- pathophysiology (3)
- pemphigus (3)
- pemphigus vulgaris (3)
- pentacene (3)
- peptide receptor radionuclide therapy (3)
- performance evaluation (3)
- perfusion (3)
- pharmacotherapy (3)
- phase transition (3)
- phenomenology (3)
- phenotypic plasticity (3)
- pheromones (3)
- photoemission (3)
- photoluminescence (3)
- photoperiodism (3)
- photosynthesis (3)
- photothrombotic stroke (3)
- phylogenetics (3)
- physical fitness (3)
- plasma (3)
- platinum (3)
- polarized training (3)
- political discourse (3)
- pollen foraging (3)
- pollinator (3)
- poly(2-ethyl-2-oxazoline) (3)
- poly(2-oxazine) (3)
- poly(2-oxazoline) (3)
- poly(2-oxazoline)s (3)
- polymer processing (3)
- polymerization (3)
- polyphenols (3)
- poor prognosis (3)
- population genetics (3)
- positron-emission-tomography (3)
- posture (3)
- predictors (3)
- preschool children (3)
- preterm (3)
- preterm birth (3)
- pro-inflammatory cytokines (3)
- process mining (3)
- processing fluency (3)
- progenitors (3)
- prognostic value (3)
- promoter (3)
- prosocial behavior (3)
- prospective study (3)
- prostate-specific membrane antigen (PSMA) (3)
- protected areas (3)
- protein folding (3)
- protein kinases (3)
- protein-protein interaction (3)
- proximal gradient method (3)
- psycho-oncology (3)
- psychometrics (3)
- psychotherapy (3)
- pulse wave velocity (3)
- purification (3)
- pyrene (3)
- pyrolysis (3)
- quality (3)
- quality control (3)
- quality indicators (3)
- quality of democracy (3)
- quality of experience (3)
- quantum dynamics (3)
- quantum mechanics (3)
- quantum physics (3)
- questionnaire (3)
- radiation therapy (3)
- radical reactions (3)
- radiology (3)
- radiomics (3)
- radionuclide therapy (3)
- radiosensitivity (3)
- randomized controlled-trial (3)
- reactivation (3)
- real-time (3)
- real-time PCR (3)
- receptor tyrosine kinases (3)
- recommendations (3)
- red blood cells (3)
- regulator (3)
- regulator genes (3)
- regulatory RNA (3)
- relief (3)
- renal cell carcinoma (3)
- reoperation (3)
- reporter gene (3)
- reporting and data system (3)
- reproduction (3)
- research (3)
- resonant tunneling diode (3)
- response regulator (3)
- retinal pigment epithelium (3)
- rhinitis (3)
- rhodesain (3)
- rhodopsin (3)
- ribosome (3)
- riboswitch (3)
- risk stratification (3)
- robustness (3)
- rotator cuff (3)
- ruthenium (3)
- salvage radiotherapy (3)
- sample (3)
- satellite data (3)
- scanning electron microscopy (3)
- school (3)
- scleroderma (3)
- secondary lung tumors (3)
- secondary metabolites (3)
- sedimentology (3)
- self-efficacy (3)
- self-regulation (3)
- semantic segmentation (3)
- semi-natural habitats (3)
- sense of agency (3)
- sensor fusion (3)
- sensory cues (3)
- sensory neurons (3)
- sentinel (3)
- sequence databases (3)
- sequestration (3)
- seroprevalence (3)
- serotonin transporter gene (3)
- sex determination (3)
- shock (3)
- sialic acid (3)
- signal peptides (3)
- signal to noise ratio (3)
- single top production (3)
- single top quark (3)
- single-molecule biophysics (3)
- skin biopsy (3)
- sleeping sickness (3)
- small-molecule activation (3)
- snRNP (3)
- social media (3)
- sol-gel (3)
- sphingolipid (3)
- spin-orbit coupling (3)
- spleen (3)
- splicing (3)
- standard model (3)
- startle disease (3)
- statistical data (3)
- statistics (3)
- stemness (3)
- stenosis (3)
- stereotactic body radiotherapy (3)
- stereotactic irradiation (3)
- stimulation (3)
- stingless bees (3)
- stochastic processes (3)
- stomach (3)
- stomata (3)
- strains (3)
- strategies (3)
- strategy (3)
- stress response (3)
- strong coupling (3)
- structure-activity relationship (3)
- substituent (3)
- subtypes (3)
- subunit (3)
- subventricular zone (3)
- sucrose (3)
- sucrose responsiveness (3)
- sudden cardiac death (3)
- superresolution (3)
- suppressor cells (3)
- surface (3)
- surgical site infection (3)
- susceptibility loci (3)
- swarming (3)
- swine (3)
- symptoms (3)
- synaptic inhibition (3)
- synaptic transmission (3)
- synchrotron radiation (3)
- synthetic biology (3)
- synthetic methods (3)
- tMCAO (3)
- teaching (3)
- team sport (3)
- temozolomide (3)
- temporal binding (3)
- temporal bone (3)
- tendon (3)
- testosterone (3)
- theoretical chemistry (3)
- thermogenesis (3)
- thin film (3)
- threat (3)
- three-dimensional imaging (3)
- thromboembolism (3)
- time-resolved photoelectron spectroscopy (3)
- timing (3)
- top quark (3)
- top quark pair (3)
- topography (3)
- total hip arthroplasty (3)
- toxins (3)
- trabectome (3)
- trabecular meshwork (3)
- trade-offs (3)
- trafficking (3)
- tranexamic acid (3)
- transactivation (3)
- transcranial direct current stimulation (3)
- transcriptional control (3)
- transcriptome analysis (3)
- transfection (3)
- transfer (3)
- transgenic mice (3)
- transmission electron microscopy (3)
- transportation (3)
- treatment outcome (3)
- treatment response (3)
- triglycerides (3)
- tropical ecology (3)
- troponin (3)
- trypanosoma (3)
- tumor necrosis factor (3)
- tundra (3)
- two-photon absorption (3)
- ultrastructure (3)
- urbanization (3)
- urinary tract infections (3)
- user-centered design (3)
- validity (3)
- vandetanib (3)
- vascular plants (3)
- vascularization (3)
- vasculitis (3)
- velocity (3)
- ventilation (3)
- viability (3)
- viral load (3)
- viral replication (3)
- virtual environments (3)
- visual orientation (3)
- von Willebrand factor (3)
- waggle dance (3)
- wall shear stress (3)
- wax (3)
- weight gain (3)
- weight loss (3)
- yoga (3)
- zinc (3)
- zinc oxide (3)
- Übergewicht (3)
- γδ T cells (3)
- "-omics" (2)
- 10-bis(dicarboximide)> (2)
- 11C-HED (2)
- 123I-mIBG (2)
- 123I-metaiodobenzylguanidine (2)
- 177Lu (2)
- 18F-FDS (2)
- 2-APB (2)
- 2015 (2)
- 2B (2)
- 2Dimensionale Spektroskopie (2)
- 3 (2)
- 3D Printing (2)
- 3D fluoroscopy (2)
- 3D model generation (2)
- 3D powder printing (2)
- 3D scaffolds (2)
- 3D tumour model (2)
- 3D-Zellkultur (2)
- 4:9 (2)
- 4D flow (2)
- 5-Azacytidine (2)
- 5-Fluorouracil (2)
- 5-HT transporter (2)
- 5-HT1A receptor (2)
- 5-HTTLPR (2)
- 5-fluorouracil (2)
- 5G (2)
- 68Ga-DOTATATE (2)
- 7 T (2)
- 7T (2)
- A1 adenosine receptors (2)
- AAA (2)
- ABCG2 (2)
- ACC (2)
- ACL (2)
- ADHS (2)
- AGN (2)
- AKT (2)
- AKT1 (2)
- ALCL (2)
- ALMT (2)
- AMADEUS (2)
- ANOVA (2)
- APOBEC3G (2)
- ARDS (2)
- ARONJ (2)
- ASC (2)
- ASM (2)
- ATF4 (2)
- Ab-initio-Rechnung (2)
- Abschirmung (2)
- Abschlussprüfung (2)
- Acetylation (2)
- Achilles (2)
- Acromyrmex fracticornis (2)
- Actin nucleation (2)
- Actinomyceten (2)
- Active Galactic Nuclei (2)
- Active galactic nucleus (2)
- Acute lymphocytic leukaemia (2)
- Acute myeloid leukemia (2)
- Acute myeloid leukemia (AML) (2)
- Adaptation (2)
- Adaptivregelung (2)
- Adaptorproteine (2)
- Adhesion GPCR (2)
- Adhesion-GPCR (2)
- Adipogenesis (2)
- Adipositas (2)
- Adjuvant (2)
- Adrenerger Rezeptor (2)
- Adrenocortical Carcinoma (2)
- African Trypanosomes (2)
- African trypanosomes (2)
- Ag(111) (2)
- Agalsidase beta (2)
- Agent (2)
- Aging (2)
- Agrobacterium tumefaciens (2)
- Aktin-Zytoskelett (2)
- Akute myeloische Leukämie (2)
- Albino rats (2)
- Alcohol (2)
- Aldehyde (2)
- Aldosteron (2)
- Algorithm (2)
- Alkaloid (2)
- Allogeneic stem cell transplantation (2)
- Alter Orient (2)
- Ameisenstaat (2)
- Ames test (2)
- Ammoniten (2)
- Amplification (2)
- Analoga (2)
- Analyse (2)
- Analysis (2)
- Ancistrocladus (2)
- Aneuploidy (2)
- Angiogenesis (2)
- Angiotensin II (2)
- Angsterkrankungen (2)
- Animal models (2)
- Anisotropie (2)
- Anode (2)
- Anoplolepis gracilipes (2)
- Anorexia nervosa (2)
- Anpassung (2)
- Antarctic ice sheet (2)
- Antenne (2)
- Anthocyane (2)
- Anthropogener Einfluss (2)
- Anti-k Jet (2)
- Antiangiogenese (2)
- Antibodies (2)
- Antiferromagnetismus (2)
- Antigen (2)
- Antigen CD28 (2)
- Antigen CD4 (2)
- Antigenpräsentation (2)
- Antimonverbindungen (2)
- Antioxidantien (2)
- Antisense (2)
- Antisense RNA (2)
- Anxiety disorder (2)
- Approximation (2)
- Aptamer (2)
- Aquaporin (2)
- Arabidopsis (2)
- Arbeitsgedächtnis (2)
- Archaea (2)
- Arginine (2)
- Aristeas (2)
- Aristeas-Brief (2)
- Aromatically annulated triquinacenes (2)
- Aromaticity (2)
- Aromatisch anellierte Triquinacene (2)
- Aromatizität (2)
- Art (2)
- Arten-Energy-Theory (2)
- Artenreichtum (2)
- Arthrose (2)
- Artificial Intelligence (2)
- Arzneimittelüberwachung (2)
- Association (2)
- Associative learning (2)
- Assoziatives Lernen (2)
- Assyriologie (2)
- Astrozyt (2)
- Atemwege (2)
- Atomic and molecular interactions with photons (2)
- Attention-deficit/hyperactivity disorder (2)
- Audit sampling (2)
- Aufsichtsrat (2)
- Augenbewegung (2)
- Augmented Reality (2)
- Aurora-A (2)
- Ausfallsicheres System (2)
- Ausfallsicherheit (2)
- Auswertung (2)
- Autism spectrum disorders (2)
- Auto-Scaling (2)
- Autoantibodies (2)
- Autoantigen (2)
- Autologous hematopoietic stem cell transplantation (2)
- Automatische Klassifikation (2)
- Autophagie (2)
- Autophagy (2)
- Autoradiography (2)
- Aversive Konditionierung (2)
- Axion (2)
- Axon degeneration (2)
- Axonal degeneration (2)
- B cell receptors (2)
- B chromosomes (2)
- B lymphocytes (2)
- B-Lymphozyten (2)
- BAD (2)
- BBCH (2)
- BCL6 (2)
- BDG (2)
- BDNF stimulation (2)
- BGK approximation (2)
- BH3-only proteins (2)
- BMP signaling (2)
- BOLD signal (2)
- BRCA2 (2)
- BRENDA (2)
- BTN3 (2)
- Bacillus (2)
- Bacillus anthracis (2)
- Bacterial infection (2)
- Bacterial meningitis (2)
- Bacterial pathogens (2)
- Bakterielle Hirnhautentzündung (2)
- Bakterielle Infektion (2)
- Bakteriengift (2)
- Bandstruktur (2)
- Bank (2)
- Base text (2)
- Baumkrone (2)
- Bavaria (2)
- Bcl-2 (2)
- Bee abundance (2)
- Bees (2)
- Begrenzte Staatlichkeit (2)
- Belyi map (2)
- Benchmark (2)
- Benin (2)
- Benutzeroberfläche (2)
- Benutzerschnittstelle (2)
- Benzene (2)
- Beobachter (2)
- Beschaffung (2)
- Bestandsmanagement (2)
- Bestrahlung (2)
- Bestärkendes Lernen <Künstliche Intelligenz> (2)
- Bestäuber (2)
- Bestäubungsökologie (2)
- Beta-1-Rezeptor (2)
- Beta-catenin (2)
- Betriebssystem (2)
- Bewegungssehen (2)
- Bewegungssteuerung (2)
- Bias (2)
- Biene <Gattung> (2)
- Bienenwolf (2)
- Big Five (2)
- Biholomorphe Abbildung (2)
- Bilderzeugung (2)
- Bilharziose (2)
- Bindestelle (2)
- Binomialverteilung (2)
- BioID (2)
- Biochemistry (2)
- Biodistribution (2)
- Biodiversity (2)
- Biofabrikation (2)
- Bioink (2)
- Bioinks (2)
- Biologische Aktivität (2)
- Biomechanics (2)
- Bioprinting (2)
- Bioreactor (2)
- Bismut (2)
- Bismuthene (2)
- Bismutselenide (2)
- Bismutverbindungen (2)
- Bitopische Liganden (2)
- Bivalves (2)
- Blei (2)
- Blickbewegung (2)
- Blood-brain barrier (2)
- Blumeria graminis (2)
- Blut (2)
- Blutgerinnung (2)
- Blutplättchen (2)
- Blutstammzelle (2)
- Body weight (2)
- Bombus (2)
- Bombus terrestris (2)
- Bone marrow (2)
- Bone morphogenetic protein-2 (2)
- Bone regeneration (2)
- Bone-marrow-transplantation (2)
- Bor-Stickstoff-Verbindungen (2)
- Boranes (2)
- Borkenkäfer (2)
- Borverbindungen (2)
- Borylenkomplexe (2)
- Box-Jenkins-Verfahren (2)
- Box–Jenkins Program (2)
- Brain endothelial cells (2)
- Brassica napus (2)
- Brazil (2)
- Breast-cancer (2)
- Breast-tumors (2)
- Brownsche Bewegung (2)
- Butyrylcholinesterase (2)
- Bärtierchen (2)
- C-H activation (2)
- C-RAF (2)
- C-X-C motif chemokine receptor 4 (2)
- C. callunae (2)
- C. efficiens (2)
- C. glutamicum (2)
- C/EBP (2)
- C57BL/6 mice (2)
- C5a (2)
- CA19-9 (2)
- CADe (2)
- CCL4 (2)
- CCR2 (2)
- CCR4 (2)
- CD-Spektroskopie (2)
- CD117 (2)
- CD23 (2)
- CD274 (2)
- CD30 (2)
- CD4(+) T-cells (2)
- CD40L (2)
- CD8 T cell (2)
- CD9 (2)
- CNN (2)
- CNO (2)
- CNS cancer (2)
- CNS disease (2)
- CNS disorders (2)
- CNV (2)
- CO2 (2)
- COMT (2)
- CORDEX Africa (2)
- CP-Parität (2)
- CRC (2)
- CRISPR (2)
- CRISPR Cas9 (2)
- CRPS (2)
- CSI (2)
- CSS (2)
- CSVD (2)
- CXCL13 (2)
- CYP2W1 (2)
- CYR61 (2)
- CaMKII (2)
- Ca\(^{2+}\) signalling (2)
- Caco2 cells (2)
- Cadmiumselenid (2)
- Calcineurin (2)
- Calciumphosphat (2)
- Calibration (2)
- Cambrian (2)
- Camponotus (2)
- Cancer immunotherapy (2)
- Cancer treatment (2)
- Capacity Management (2)
- Carcinogenität (2)
- Cardiomyocyte (2)
- Cardiomyopathy (2)
- Cardiovascular disease (2)
- Cardiovascular diseases (2)
- Cardiovascular risk factors (2)
- Cartilage (2)
- Cartilage Tissue Engineering (2)
- Cas9 (2)
- Cascading Style Sheets (2)
- Cayley graph (2)
- CdSe (2)
- Cdu1 (2)
- CePt5 (2)
- Cell (2)
- Cell adhesion (2)
- Cell cycle (2)
- Cell migration (2)
- Cell therapy (2)
- Cement (2)
- Ceramide (2)
- Cerebellum (2)
- Cerebrospinal fluid (2)
- ChIP-sequencing (2)
- ChR2 (2)
- Chagas disease (2)
- Channelrhodopsin-2 (2)
- Chaos (2)
- Chaostheorie (2)
- Chaotisches System (2)
- Chaperone (2)
- Charcot-Marie-Syndrom (2)
- Charcot-Marie-Tooth disease (2)
- Chemische Bindung (2)
- Chemokine (2)
- Chemotherapie (2)
- Childhood (2)
- Childhood medulloblastoma (2)
- Chili RNA Aptamer (2)
- ChlaDUB1 (2)
- Chlamydia pneumoniae (2)
- Cholinesterase (2)
- Chondrogenesis (2)
- Chorasan (2)
- Christentum (2)
- Christianity (2)
- Chromatin structure (2)
- Chromatographie (2)
- Chronic heart failure (2)
- Chronic kidney disease (2)
- Chronophin (2)
- Chrysididae (2)
- Circadian clock (2)
- Cirl (2)
- Cisplatin (2)
- Cl Lowe limit (2)
- Clinical Neuroradiology (2)
- Clinical trial (2)
- Cloud Gaming (2)
- Code examples (2)
- Coffin-Lowry syndrome (2)
- Cognitive conflict (2)
- Coherent control (2)
- Collagen (2)
- Colombia (2)
- Colonization (2)
- Combination (2)
- Computerunterstütztes Lernen (2)
- Concealed Information Test (2)
- Confidence interval (2)
- Conformal field theory (2)
- Conical Intersections (2)
- Conservation (2)
- Consistent partial least squares (2)
- Constraints (2)
- Contaminants (2)
- Content Management (2)
- Controllability (2)
- Corannulene (2)
- Corporate Governance (2)
- Correlated Fermions (2)
- Correlative microscopy (2)
- Corynebacterium callunae (2)
- Corynebacterium efficiens (2)
- Corynebacterium glutamicum (2)
- Cosmology (2)
- Coulomb-Blockade (2)
- Coupled Cluster (2)
- CpG (2)
- Crohn's disease (2)
- Crohn’s disease (2)
- Cross-section (2)
- Crosstalk (2)
- Cryo-EM (2)
- CsrA (2)
- Cu(111) (2)
- Cuprate (2)
- Cushing-Syndrom (2)
- Cushing’s disease (2)
- Cuticle (2)
- Cuticular waxes (2)
- Cyclization (2)
- Cyclo-GMP (2)
- Cyclovoltammetrie (2)
- Cys-loop receptor (2)
- Cytokines (2)
- Cytotoxicity (2)
- D-Norm (2)
- DAPI staining (2)
- DASH (2)
- DHAP (2)
- DIRA (2)
- DLBCL (2)
- DM-domain gene (2)
- DNA Binding (2)
- DNA Methylation (2)
- DNA Repair (2)
- DNA Schaden (2)
- DNA antibodies (2)
- DNA barcoding (2)
- DNA damage response (2)
- DNA helicase (2)
- DNA storage (2)
- DNA-PK (2)
- DNA-Reparatur (2)
- DNA-repair (2)
- DNA/RNA sensors (2)
- DNS-Bindung (2)
- DNS-Sequenz (2)
- DNS-Topoisomerasen (2)
- DOT1 (2)
- DOTATOC (2)
- DREAM (2)
- DRG (2)
- DROSHA (2)
- DSG2 (2)
- DTI (2)
- DYT1 (2)
- Dark-Matter (2)
- Darmepithel (2)
- Darstellungsmatrix (2)
- Data-driven Operations Management (2)
- Database (2)
- Datenfusion (2)
- Decision Support Systems (2)
- Deep Learning (2)
- Deep sequencing (2)
- Deformationsquantisierung (2)
- Deletion (2)
- Demethylierung (2)
- Dendritische Zellen (2)
- Development (2)
- Dezentrale Regelung (2)
- Diabetes (2)
- Diabetic polyneuropathy (2)
- Diagnose (2)
- Diagnostic medicine (2)
- Diamiktit (2)
- Diethylstilbestrol (2)
- Difenidol (2)
- Differential effects of stressors (2)
- Differentielle Genexpression (2)
- Diffusion coefficient (2)
- Digital Elevation Model (2)
- Digital Religions (2)
- Digital Religions Education (2)
- Digitale Signalverarbeitung (2)
- Dihydrooxazole (2)
- Dimension 2 (2)
- Dimension 3 (2)
- Dirichlet-Reihe (2)
- Disease (2)
- Diseases (2)
- Diskursanalyse (2)
- Distributed computing (2)
- Domäne (2)
- Dose response (2)
- Dose-response relationship (2)
- Dosimetry (2)
- Dot-Depth Problem (2)
- Down syndrome (2)
- Dreiecksgitter (2)
- Drogen (2)
- Drug development (2)
- Duchenne muscular dystrophy (2)
- Dwyka (2)
- Dyade (2)
- Dyes (2)
- Dynamics (2)
- Dynamik (2)
- Düne (2)
- Dünnschichtsolarzelle (2)
- Dünnschichttransistor (2)
- E-Learning (2)
- E-cadherin (2)
- E. coli Nissle 1917 (2)
- E. coli serotype 06 (2)
- EDA-NOCV (2)
- EEA (2)
- EF-1A (2)
- EGF (2)
- EMT (2)
- ERK signaling (2)
- ERT (2)
- EUROASPIRE (2)
- EW (2)
- EZH2 (2)
- Early Basso Continuo (2)
- Early Music (2)
- Early-onset (2)
- Earnings Quality (2)
- Echinococcosis (2)
- Echinococcus multilocularis (2)
- Ecological Momentary Assessment (2)
- Ecosystem services (2)
- Effektive Theorie (2)
- Efficiency (2)
- Effizienter Algorithmus (2)
- Eigenwert (2)
- Einfluss (2)
- Eingeweidewürmer (2)
- Einzelhandel (2)
- Einzelzellanalyse (2)
- Eiparasitismus (2)
- Eisen (2)
- Eisenkomplexe (2)
- Elderly (2)
- Electroencephalography (2)
- Electromagnon (2)
- Electron Microscopy (2)
- Electron Transfer (2)
- Electronic spectroscopy (2)
- Electropermeabilization (2)
- Elektrochromie (2)
- Elektroencephalogramm (2)
- Elektromagnon (2)
- Elektromyographie (2)
- Elektron-Phonon-Wechselwirkung (2)
- Elektronendichteverteilung (2)
- Elektronenflüssigkeit (2)
- Elektronengas (2)
- Elektronenspektroskopie (2)
- Elektronenspinresonanzspektroskopie (2)
- Elektronische Eigenschaft (2)
- Elektronische Spektroskopie (2)
- Elektroporation (2)
- Elementarteilchen (2)
- Elfenbeinküste (2)
- Embodiment (2)
- Emotion regulation (2)
- Emotional processing (2)
- Emotionen (2)
- Emotionserkennung (2)
- Empirical Analysis (2)
- Endophytische Pilze (2)
- Engadin (2)
- Enoyl-acyl-carrier-protein-Reductase <Enoyl-[acyl-carrier-protein]-Reductase> (2)
- Entanglement (2)
- Entmarkung (2)
- Entropie (2)
- Entscheidbarkeit (2)
- Entscheidungen (2)
- Entstehung (2)
- Entwicklungsländer (2)
- Environment (2)
- Enzyme (2)
- Epidemiologie (2)
- Epidemiology (2)
- Epidermaler Wachstumsfaktor (2)
- Epigenese (2)
- Epiphyten (2)
- Epitope (2)
- Epitranscriptomics (2)
- Erdbeobachtung (2)
- Erfahrung (2)
- Ernteertrag (2)
- Essverhalten (2)
- Estradiol (2)
- Estrogen (2)
- Ethernet (2)
- Europa (2)
- European Organization for Nuclear Research. ATLAS Collaboration (2)
- European Union (2)
- Europäische Union (2)
- Europäische Zentralbank (2)
- Event (2)
- Event-related potential (2)
- Event-related potentials (2)
- Evolutionspsychologie (2)
- Exacerbation (2)
- Exciton coupling (2)
- Exekutive Funktionen (2)
- Exercise capacity (2)
- Exercise testing (2)
- Exotics (2)
- Expansionsmikroskopie (2)
- Experimental physics (2)
- Explainable AI (2)
- Explainable Artificial Intelligence (2)
- Explosion (2)
- Extended Reality (2)
- Extensions of gauge sector (2)
- Extracellular Vesicles (2)
- Extracellular matrix (2)
- Extrazellulärraum (2)
- Extreme Value Theory (2)
- Extremereignisse (2)
- Extremwert (2)
- Exziton-Polariton (2)
- Exzitonenkopplung (2)
- F-actin (2)
- F8 fimbriae (2)
- FAAH (2)
- FCS (2)
- FDG PET/CT (2)
- FDG-PET/CT (2)
- FGF-pathway (2)
- FGFR1 (2)
- FIB-4 (2)
- FISH (2)
- FKBP5 (2)
- FRET sensors (2)
- FSHD (2)
- FT-IR-Spektroskopie (2)
- FTIR spectroscopy (2)
- FabI (2)
- Fabry genotype (2)
- Fabry nephropathy (2)
- Fabry phenotype (2)
- Factor receptor (2)
- Fagus sylvatica (2)
- Fahren (2)
- Fahrerassistenz (2)
- Fanconi Anämie (2)
- Farbensehen (2)
- Fc-receptor (2)
- FcγR (2)
- Fear (2)
- Fear conditioning (2)
- Feldeffekttransistor (2)
- Feldtheorie (2)
- Female (2)
- Femtochemistry (2)
- Femtosekunden (2)
- Femtosekundenlaser (2)
- Fernwartung (2)
- Ferromagnetikum (2)
- Ferromagnetische Halbleiter (2)
- Ferroptosis (2)
- Fibromyalgia (2)
- Finanzkrise (2)
- Finanzmathematik (2)
- Fingerprint-Verfahren (2)
- Fish (2)
- Flavonoide (2)
- Flavonoids (2)
- Flavourmischung (2)
- Flow cytometry (2)
- Fluconazole (2)
- Fluid (2)
- Fluorescence microscopy (2)
- Fluoreszenzkorrelationsspektroskopie (2)
- Fokker–Planck equation (2)
- Foldamers (2)
- Formation Flight (2)
- Formulation development (2)
- Formulierung (2)
- Fossil (2)
- Fossile Muscheln (2)
- FoxO3 (2)
- Framework <Informatik> (2)
- Freies Molekül (2)
- Frequency Domain (2)
- Frucht (2)
- Fullerene (2)
- Funktionalisierung <Chemie> (2)
- Funktionelle Bildgebung (2)
- Funktionelle NMR-Tomographie (2)
- Furylborane (2)
- Fusarium (2)
- Fusion proteins (2)
- Future Internet (2)
- Förster Resonance Energy Transfer (2)
- Förster Resonanz Energie Transfer (2)
- G-protein (2)
- G-quadruplexes (2)
- GABA-Rezeptor (2)
- GABAA receptors (2)
- GABP (2)
- GAD1 (2)
- GIS (2)
- GLP-1 (2)
- GLUT2 (2)
- GLUT3 (2)
- GLV-1H68 (2)
- GM-CSF (2)
- GRAPPA (2)
- GTP-bindende Proteine (2)
- GUT (2)
- GaMnAs (2)
- Galaxienhaufen (2)
- Galectine (2)
- Galeruca tanaceti (2)
- Galois-Theorie (2)
- Gamma (2)
- Gamma-Burst (2)
- Gamma-Konvergenz (2)
- Gas chromatography (2)
- Geldtheorie (2)
- Gemeinschaftsökologie (2)
- Gen notch (2)
- Gene cloning (2)
- Gene duplication (2)
- Gene therapy (2)
- Generalisierung (2)
- Generalized Nash Equilibrium Problem (2)
- Genes (2)
- Genetics research (2)
- Genotoxizität (2)
- Geoarchäologie (2)
- Geophysics (2)
- Gerinnungsfaktor XII (2)
- German Hepatitis C-Registry (2)
- German people (2)
- Geschlechtsdifferenzierung (2)
- Geschlechtsunterschied (2)
- Gesteinsbildung (2)
- Gesundheitswesen (2)
- Gewebemodell (2)
- Gitterbaufehler (2)
- Glatiramer acetate (2)
- Glaukom (2)
- Gleichverteilung (2)
- Gletscherschwankung (2)
- Gliederfüßer (2)
- Gliom (2)
- Glioma (2)
- Globale Optimierung (2)
- Glomeruli (2)
- Gluino production (2)
- Glukose (2)
- Glutamin (2)
- Glycoengineering (2)
- Glykoproteine (2)
- Gold Nanoparticles (2)
- Golf von Akaba (2)
- Golgi apparatus (2)
- Golgi-Apparat (2)
- Gondwana (2)
- Gothenburg model (2)
- Graft-versus-host-disease (2)
- Graft-versus-leukemia (2)
- Granulit (2)
- Gravitation (2)
- Grippe (2)
- Group B Streptococcus (2)
- Grundsubstanz (2)
- Grundvorstellung (2)
- Grundwasserneubildung (2)
- Guanidinderivate (2)
- Guidelines (2)
- Guillain-Barre-Syndrome (2)
- Guillain-Barré-Syndrom (2)
- Guinea-pig uterus (2)
- H-1-NMR spectroscopy (2)
- HBV (2)
- HDAC (2)
- HFQ (2)
- HGF (2)
- HHV-6 (2)
- HIV-Infektion (2)
- HKT transporter (2)
- HLA-G (2)
- HPA axis (2)
- HPP (2)
- HPV (2)
- HRV (2)
- HRXRD (2)
- HSC (2)
- HUVEC (2)
- Habichtskraut (2)
- Habitat (2)
- Habitat fragmentation (2)
- Haemophilus influenzae (2)
- Haftung (2)
- Halbleiter-Supraleiter-Kontakt (2)
- Halbleiteroberfläche (2)
- Halbsandwich-Verbindungen (2)
- Halcyon (2)
- Halictidae (2)
- Hamburg (2)
- Handlungsregulation (2)
- Hardware (2)
- Haut (2)
- Healthy subjects (2)
- Helminths (2)
- Hemolysin (2)
- Hemostasis (2)
- Heparin (2)
- Herpes (2)
- Herpesviren (2)
- Herpesvirus (2)
- Herstellung (2)
- Herzfrequenzvariabilität (2)
- Heterocyclen (2)
- Heterocycles (2)
- Heterocyclische Verbindungen (2)
- Heuschrecken (2)
- Heusler (2)
- Heuslersche Legierung (2)
- Hexahydro-sila-difenidol analogues (2)
- Hey (2)
- Hieracium (2)
- Higgs-Teilchen (2)
- High throughput screening (2)
- Hippo pathway (2)
- Hippo signaling (2)
- Hirnforschung (2)
- Histon-Methyltransferase (2)
- Hitzeschockproteine (2)
- Hochauflösende Mikroskopie (2)
- Hochauflösendes Verfahren (2)
- Hochbegabung (2)
- Holocene (2)
- Holothuria spinifera (2)
- Holozän (2)
- Homogener Raum (2)
- Homöostase (2)
- Honey bee (2)
- Hormone (2)
- Hospitalization (2)
- Host-parasite interaction (2)
- Host-parasite interactions (2)
- Host-pathogen interaction (2)
- Host-pathogen interactions (2)
- Human behaviour (2)
- Human brain (2)
- Human papillomavirus (2)
- Human-Computer Interaction (2)
- Human-Robot-Interaction (2)
- Hunger (2)
- Hurwitz-Raum (2)
- Hyaluronic Acid (2)
- Hybrid (2)
- Hyperbolische Differentialgleichung (2)
- Hypertension (2)
- Hypertrophy (2)
- Hypervalentes Molekül (2)
- Hypothetical gauge bosons (2)
- Hämodialyse (2)
- Hörverlust (2)
- I-tasser (2)
- IAP (2)
- IAPS (2)
- ICD (2)
- ICEP (2)
- IEEE 802.11 (2)
- IENFD (2)
- IFN-gamma (2)
- IFN-γ (2)
- IL-17 (2)
- IL-5 (2)
- IL-6 (2)
- ILEX (2)
- IMAT (2)
- IMRT (2)
- IN-VIVO (2)
- IR (2)
- IR spectroscopy (2)
- ISS (2)
- ITAM (2)
- Ibo (2)
- Ibrutinib (2)
- Identification (2)
- IgG (2)
- Igbo (2)
- Ighmbp2 (2)
- Illustration (2)
- Image-guidance (2)
- Imaging techniques (2)
- Immobilienmarkt (2)
- Immunantwort (2)
- Immunization (2)
- Immunohistochemistry (2)
- Immunological synapse (2)
- Immunosuppression (2)
- Immuntoleranz (2)
- Impact (2)
- Impulsformung (2)
- Impulsivität (2)
- Impulslaser (2)
- In vitro models (2)
- Individualität (2)
- Induced apoptosis (2)
- Induced pluripotent stem cells (2)
- Inelastische Röntgenstreuung (2)
- Infection (2)
- Infections (2)
- Infectious disease (2)
- Infektionsmodell (2)
- Inflammatory pain (2)
- Inflation Targeting (2)
- Infrarot (2)
- Infrarot-Spektroskopie (2)
- Inhibitorische Synapse (2)
- Inhibitory synapse (2)
- Innere Uhr (2)
- Innovation Incentives (2)
- Insekt (2)
- Insulin-like Growth Factor I (2)
- Integrated network analysis (2)
- Integrin (2)
- Interference microscopy (2)
- Interferon (2)
- Interferon <gamma-> (2)
- Intergenerational income mobility (2)
- Intergenerative Einkommensmobilität (2)
- Interleukin (2)
- Interleukin 2 (2)
- Interleukin 5 (2)
- Interleukin-4 (2)
- Interleukin-6 (2)
- International Comparative Research (2)
- Intuition (2)
- Inversion Symmetry Breaking (2)
- Ioflupane (2)
- Iridiumkomplexe (2)
- Isolation (2)
- Isomorphie (2)
- J- and H-Aggregate (2)
- J- and H-Aggregates (2)
- JES uncertainty (2)
- Jena Experiment (2)
- Jets (2)
- Josephson junctions (2)
- Judit <Buch> (2)
- Judith <Book> (2)
- J‐aggregates (2)
- K+ channels (2)
- K-RAS (2)
- K-Ras (2)
- KDELR2 (2)
- KDIGO (2)
- KEAP1 (2)
- KIT (2)
- Kalahari (2)
- Kaliumkanal (2)
- Kanalbildner (2)
- Kapazitätsplanung (2)
- Kapillarelektrophorese (2)
- Kaposi sarcoma (2)
- Karbon (2)
- Karriere (2)
- Kartierung (2)
- KasA (2)
- Kathode (2)
- Keldysh formalism (2)
- Kenya (2)
- Kernhülle (2)
- Kernspintomographie (2)
- Ketogenic diet (2)
- Ki67 (2)
- Kidney function (2)
- Kilimanjaro (2)
- Kilombero (2)
- Kinase (2)
- Kinetoplastida (2)
- Kirche (2)
- Klassifikation (2)
- Klassifikations- und Regressionsbaum (2)
- Kleinkern (2)
- Klimaschwankung (2)
- Klinische Studie (2)
- Knochenersatz (2)
- Knochenmark (2)
- Knochenmarktransplantation (2)
- Knochenregeneration (2)
- Knockout-Maus (2)
- Knorpelzelle (2)
- Knowledge Management (2)
- Kognitive Kontrolle (2)
- Kognitive Psychologie (2)
- Kognitiver Prozess (2)
- Kohlendioxid (2)
- Kohlenhydrate (2)
- Kohomologie (2)
- Kohärente 2D Spektroskopie (2)
- Kohärente Anregung (2)
- Kohärente Multidimensionale Spektroskopie (2)
- Kohärente Optik (2)
- Kohärenz (2)
- Kollagen (2)
- Kolonieerkennung (2)
- Kommunikationsprotokoll (2)
- Kompakte Lie-Gruppe (2)
- Komplement (2)
- Komplement <Immunologie> (2)
- Komplementaritätsproblem (2)
- Komplexe (2)
- Komplexitätsklasse (2)
- Komponentenanalyse (2)
- Kondo-Modell (2)
- Kondo-System (2)
- Kongo (2)
- Konjugate (2)
- Kontextkonditionierung (2)
- Kontrolle (2)
- Kooperation (2)
- Koordinationslehre (2)
- Koordinationsverbindungen (2)
- Kopula <Mathematik> (2)
- Korrelative Mikroskopie (2)
- Korruption (2)
- Kosmische Strahlung (2)
- Kraftfahrzeugindustrie (2)
- Kraftfeld (2)
- Kraftmikroskopie (2)
- Krankheit (2)
- Krebsimmuntherapie (2)
- Kreditmarkt (2)
- Kreuzung (2)
- Kristall (2)
- Kristallographie (2)
- Kulturpolitik (2)
- Kulturwissenschaft (2)
- Körpergewicht (2)
- L-arginine (2)
- L929 (2)
- LAD (2)
- LEEM (2)
- LINC (2)
- LMHFV (2)
- LOFAR (2)
- LPP (2)
- LST (2)
- Lamina (2)
- Lampbrush chromosomes (2)
- Landnutzungsgradient (2)
- Landsat time series (2)
- Landschaft (2)
- Landwirtschaft / Nachhaltigkeit (2)
- Langerhans-Inseln (2)
- Larvae (2)
- Laser Pulse Shaping (2)
- Laserchemie (2)
- Laserimpulsformung (2)
- Lasertechnologie (2)
- Latin America (2)
- Lebensalter (2)
- Lebensdauer (2)
- Lebensmittelchemie (2)
- Lebensqualität (2)
- Lernerfolg (2)
- Lernkurve (2)
- Lesen (2)
- Letter of Aristeas (2)
- Lewis acidity (2)
- Licht (2)
- Lichtheimia (2)
- Lie groups (2)
- Lineares System (2)
- Lipid Bilayer Membran (2)
- Lipid Raft (2)
- Lipofuscin (2)
- Lipopolysaccharide (2)
- Liposomen (2)
- Liquid Crystal (2)
- Listeria (2)
- Literaturwissenschaft (2)
- Ljapunov-Stabilitätstheorie (2)
- Locomotor activity (2)
- Loewner theory (2)
- Loewner-Theorie (2)
- Longitudinally extensive transverse myelitis (LETM) (2)
- Low Earth Orbit (2)
- Lung-cancer (2)
- Luttinger liquid (2)
- Lyapunov functions (2)
- Lymphocytes (2)
- Lymphom (2)
- Lymphoma (2)
- Lymphozyten (2)
- M2 (2)
- MAG3 (2)
- MAP Kinase (2)
- MAPK (2)
- MAPK signaling cascades (2)
- MASK (2)
- MATQ-seq (2)
- MAX (2)
- MC event generator (2)
- MCC950 (2)
- MCPH1 (2)
- MDR (2)
- MDSCs (2)
- ME/CFS (2)
- MEG (2)
- MHC I (2)
- MIR-Spektroskopie (2)
- MITE (2)
- MLST (2)
- MP-DCCP (2)
- MPFL (2)
- MPI (2)
- MPS1 (2)
- MRI criteria (2)
- Machine learning (2)
- Magnetfeld (2)
- Magnetic Topological Insulator (2)
- Magnetic resonance (2)
- Magnetische Anisotropie (2)
- Magnetische Eigenschaft (2)
- Magnetischer Röntgenzirkulardichroismus (2)
- Magnetit (2)
- Magnetoelektrischer Effekt (2)
- Magnetohydrodynamik (2)
- Magnetotransport (2)
- Magnon (2)
- Main-group chemistry (2)
- Mais (2)
- Major depression (2)
- Majorana fermions (2)
- Makuladegeneration (2)
- Malaysia (2)
- Malignant hyperthermia (2)
- Mammakarzinom (2)
- Manganate (2)
- Mantle cell lymphoma (2)
- Mapping (2)
- Marine sponges (2)
- Markarian 501 (2)
- Marker (2)
- Markov-Ketten-Monte-Carlo-Verfahren (2)
- Marxismus (2)
- Marxist theory (2)
- Maschinelles Sehen (2)
- Masern (2)
- Mast cells (2)
- Mastzelle (2)
- Mathematical modeling (2)
- Matlab (2)
- Mausmodell (2)
- Mechanistic model (2)
- Mechanosensation (2)
- Media Psychology (2)
- Mediendidaktik (2)
- Medienkonsum (2)
- Medienpsychologie (2)
- Medienpädagogik (2)
- Megakaryocytes (2)
- Megakaryopoese (2)
- Mehrfachtätigkeit (2)
- Mehrgitterverfahren (2)
- Mekong (2)
- Melanin (2)
- Meliponini (2)
- Membran (2)
- Membranrezeptor (2)
- Membrantransport (2)
- Memory B cells (2)
- Mena (2)
- Mensch-Maschine-Interaktion (2)
- Mensch-Maschine-System (2)
- Mensch-Roboter-Interaktion (2)
- Merkel-Zellkarzinom (2)
- Merocyanine dyes (2)
- Mesenchymal stem cell (2)
- Mesenchymal stem cells (2)
- Mesenchymal stem/stromal cells (2)
- Mesenchymale Stammzellen (2)
- Mesenteric circulation (2)
- Messenger-RNP (2)
- Met (2)
- Meta-model (2)
- Metabolic pathways (2)
- Metadynamics (2)
- Metagenomics (2)
- Metall-Isolator-Phasenumwandlung (2)
- Metalloprotease (2)
- Metamorphose <Geologie> (2)
- Metastatic breast cancer (2)
- Methode (2)
- Methotrexate (2)
- Methylphenidat (2)
- Metrics (2)
- Mexico (2)
- MicroRNAs (2)
- Microcirculation (2)
- Microenvironment (2)
- Micromegas (2)
- Micronucleus (2)
- Midkine (2)
- Mikroarray (2)
- Mikroevolution (2)
- Mikromagnetismus (2)
- Mikroorganismus (2)
- Ming dynasty (2)
- Mini Unmanned Aerial Vehicle (2)
- Mitochondrien (2)
- Mittelmeerraum (2)
- Miz1 (2)
- Mobility (2)
- Modeling (2)
- Modifizierung (2)
- Molecular beam epitaxy (2)
- Molecular biology (2)
- Molecular neuroscience (2)
- Molecules (2)
- Molekülstruktur (2)
- Molekülzustand (2)
- Monarchfalter (2)
- Monetary Conditions Index (2)
- Monitorüberwachung (2)
- Monte Carlo Simulation (2)
- Morbus Fabry (2)
- Morocco (2)
- Motilität (2)
- Motion detection (2)
- Motoneuron-Krankheit (2)
- Motorische Endplatte (2)
- Mott-Isolator (2)
- Mott-Übergang (2)
- Mouse Model (2)
- Mouse model (2)
- Mouse-brain (2)
- Multidrug-Resistenz (2)
- Multiferroics (2)
- Multiferroikum (2)
- Multipolverfeinerung (2)
- Multisensory integration (2)
- Multitasking (2)
- Multivariate Analyse (2)
- Multivariate analysis (2)
- Multiwellenlängen (2)
- Muscarinic receptor antagonists (2)
- Muscheln (2)
- Mushroom bodies (2)
- Mustererkennung (2)
- Mutagenese (2)
- Mutagenität (2)
- Mutante (2)
- Mutations (2)
- Mutationsanalyse (2)
- Mycolic acid (2)
- Mykolsäuren (2)
- Myokardinfarkt (2)
- N ligands (2)
- N-Heterocyclic Carbenes (2)
- N-MYC (2)
- N-formyl peptides (2)
- N-heterocyclic carbene (2)
- N400 (2)
- NA (2)
- NEUROWIND (2)
- NF-Kappa-B (2)
- NF-kappa-B (2)
- NFkB (2)
- NFkappaB (2)
- NK cell (2)
- NLS (2)
- NMD (2)
- NMDAR (2)
- NMOSD (2)
- NO (2)
- NOAC (2)
- NONO (2)
- NOTCH (2)
- NP-hardness (2)
- NRPS (2)
- NVP-BEZ235 (2)
- Nahrungsaufnahme (2)
- Nahrungsdeprivation (2)
- Nanoantenne (2)
- Nanodiamant (2)
- Nanomedizin (2)
- Nanowire (2)
- Naphthylisoquinoline (2)
- Nasonia (2)
- Nationale Minderheiten (2)
- Natural products (2)
- Navigation (2)
- Nervensystem (2)
- Neue Medien (2)
- Neural Differentiation (2)
- Neural circuits (2)
- Neuralgie (2)
- Neuralleiste (2)
- Neuroblast (2)
- Neuroendocrine Tumor (2)
- Neurofascin (2)
- Neurofilament (2)
- Neuromodulation (2)
- Neuronal ceroid lipofuscinosis (2)
- Neuronal plasticity (2)
- Neuronale Netze (2)
- Neuropathic pain (2)
- Neuropathischer Schmerz (2)
- Neuropsychologie (2)
- Neutrino Telescope (2)
- Neutrinooszillation (2)
- Neutrinos (2)
- Newton Methods (2)
- Nfatc1 (2)
- NiMnSb (2)
- Nicht-kleinzelliges Bronchialkarzinom (NSCLC) (2)
- Nichtlineare Kontrolltheorie (2)
- Nichtlineare Optik (2)
- Nickelkomplexe (2)
- Nicotiana tabacum (2)
- Nicotinischer Acetylcholinrezeptor (2)
- Niederdimensionales System (2)
- Niederschlag (2)
- Nikaido-Isoda function (2)
- Nisthilfe (2)
- Nitrate Reductase (2)
- Nociceptor (2)
- Non-coding RNAs (2)
- Nonadiabatic quantum dynamics (2)
- Nuclear envelope (2)
- Nucleolus (2)
- Nucleoside (2)
- Nukleotid-Exzisions-Reparatur (2)
- Numerical analysis (2)
- OCB (2)
- OCD (2)
- ODMR-Spektroskopie (2)
- OLEDs (2)
- OSMR (2)
- Oberfläche (2)
- Oberflächenfunktionalisierung (2)
- Oberflächenplasmon (2)
- Oberflächenverstärkter Raman-Effekt (2)
- Ockham (2)
- Octopamin (2)
- Octopamine (2)
- Olea (2)
- Olfaktion (2)
- Oligomerisation (2)
- Omega-3-Fettsäuren (2)
- Onchozerkose (2)
- Oncogene (2)
- Oncolysis (2)
- Oncostatin M (2)
- Ontogenie (2)
- Ontologie <Wissensverarbeitung> (2)
- Oocytes (2)
- Oogenese (2)
- Oomyzus galerucivorus (2)
- Operante Konditionierung (2)
- Opioide (2)
- Optical Character Recognition (2)
- Optical Music Recognition (2)
- Optimale Steuerung (2)
- Optimierungsproblem (2)
- Optische Antenne (2)
- Optische Fernerkundung (2)
- Oranje (2)
- Organic Chemistry (2)
- Organic Semiconductors (2)
- Organic semiconductors (2)
- Organische Halbleiter (2)
- Organoids (2)
- Orthoptera (2)
- Osteogenesis (2)
- P53 (2)
- PAF1c (2)
- PAPA (2)
- PAR-CLIP (2)
- PARK2 (2)
- PCI (2)
- PDGF (2)
- PIP2 (2)
- PLEKHG5 (2)
- PML (2)
- PMMA (2)
- PPGL (2)
- PROLOG <Programmiersprache> (2)
- PROM (2)
- PSA (2)
- PSMA I&T (2)
- PSMA-PET (2)
- PTCL (2)
- PTSD (2)
- Paediatric (2)
- Pair production (2)
- Palaeoecology (2)
- Panikstörung (2)
- Paracyclophane (2)
- Parallel Imaging (2)
- Parametrisierung (2)
- Parc National de la Comoé (2)
- Parity Anomaly (2)
- Parkinson Disease (2)
- Parkinsonism (2)
- Partial Least Squares Path Modeling (2)
- Pathogenesis (2)
- Pathogenicity (2)
- Pathology (2)
- Pathophysiologie (2)
- Patron Distributions (2)
- Patterns (2)
- Pentacen (2)
- Performance (2)
- Performance practice (2)
- Pericyclische Reaktion (2)
- Period (2)
- Peripheral nervous system (2)
- Peripheres Nervensystem (2)
- Permokarbon (2)
- Personality (2)
- Perylenbisdicarboximide (2)
- Perylenbisdicarboximide <Perylen-3 (2)
- Perylenbisimide (2)
- Perylendianhydrid (2)
- Perylene bisimide (2)
- Peyer's patch (2)
- Pflanzenschutzmittel (2)
- Pflanzenökologie (2)
- Pharmacokinetic (2)
- Pharmacokinetics (2)
- Pharmakotherapie (2)
- Pharmazeutischer Hilfsstoff (2)
- Phase Transition (2)
- Phase-II (2)
- Phobie (2)
- Phonologie (2)
- Phonologische Bewusstheit (2)
- Phosphatasen (2)
- Phosphine (2)
- Phosphoglykolatphosphatase (2)
- Phospholipase D (2)
- Photocatalysis (2)
- Photochemische Reaktion (2)
- Photochromie (2)
- Photodissoziation (2)
- Photoemission (2)
- Photolithographie (2)
- Photonischer Kristall (2)
- Photophysics (2)
- Photorezeptor (2)
- Photostrom (2)
- Phylogeny (2)
- Physics beyond the Standard Model (2)
- Physikalische Eigenschaft (2)
- Phytochemie (2)
- Phänotyp (2)
- Pilze (2)
- PlanetScope (2)
- Plant Protection (2)
- Plant cuticle (2)
- Plant-insect interactions (2)
- Plasma-membrane (2)
- Plasmaantrieb (2)
- Plasmonik (2)
- Plasmozytom (2)
- Plastizität (2)
- Platelet activating Factor (2)
- Pluripotency (2)
- Plus plus (2)
- Polarisationspulsformung (2)
- Polo-like kinase 1 (2)
- Poly(2-oxazolin)e (2)
- Poly(2-oxazoline) (2)
- Poly(2-oxazoline)s (2)
- Polyadenylierung (2)
- Polyatomare Verbindungen (2)
- Polychromophores System (2)
- Polycomb (2)
- Polygynie (2)
- Polyimido Anions (2)
- Polyimidoanionen (2)
- Polymer (2)
- Polymerhalbleiter (2)
- Polymerlösung (2)
- Polyneuropathie (2)
- Polyoxazoline (2)
- Poorly water soluble drugs (2)
- Populationsgenetik (2)
- Populationskinetik (2)
- Populationspharmakokinetik (2)
- Pore (2)
- Porenbildung (2)
- Porifera (2)
- Porphyrin (2)
- Positronen-Emissions-Tomographie (2)
- Post-transcriptional regulation (2)
- Posttranslationale Änderung (2)
- Pp Collision (2)
- Prediction (2)
- Prediction interval (2)
- Predictive Analytics (2)
- Predictors (2)
- Prefrontal cortex (2)
- Primates (2)
- Priming (2)
- Prion (2)
- Prior information (2)
- ProQ (2)
- Probiotic (2)
- Probiotikum (2)
- Progenitor (2)
- Program (2)
- Promotion (2)
- Promotor <Genetik> (2)
- Prostatakrebs (2)
- Protease-sensitive release (2)
- Protected areas (2)
- Protein folding (2)
- Proteinfaltung (2)
- Proteininteraktion (2)
- Proteinkinase B (2)
- Proteinkinase C (2)
- Proteintyrosinphosphatase (2)
- Proteom (2)
- Proteomanalyse (2)
- Proton-Proton-Streuung (2)
- Prädation (2)
- Präferenz (2)
- Präfrontaler Cortex (2)
- Prävention (2)
- Pseudomonas aeruginosa (2)
- Psychiatric disorders (2)
- Psychische Gesundheit (2)
- Psychische Störung (2)
- Psychology (2)
- Psychometrie (2)
- Psychotherapie (2)
- Pteromalidae (2)
- Pulmonary imaging (2)
- Purkinje cells (2)
- Pycnogenol (2)
- Pyren (2)
- Pyrolyse (2)
- Pädagogische Psychologie (2)
- Pädiatrie (2)
- QAHE (2)
- QIVIVE (2)
- QMC (2)
- QST (2)
- QTL analysis (2)
- Quadruplex-DNS (2)
- Qualität (2)
- Qualitätskontrolle (2)
- Quanten-Vielteilchensysteme (2)
- Quantenchromodynamik (2)
- Quantenelektrodynamik (2)
- Quantenkosmologie (2)
- Quantenmechanisches System (2)
- Quantentheorie (2)
- Quantum Chemistry (2)
- Quantum Hall effect (2)
- Quantum Information (2)
- Quantum Spin Hall Effect (2)
- Quantum anomalous Hall effect (2)
- Quantum dynamics (2)
- Quartär (2)
- R factor = 0.027 (2)
- R package (2)
- RAF (2)
- RCC (2)
- REMPI (2)
- RHEED (2)
- RHO (2)
- RKIP (2)
- RNA Enzymes (2)
- RNA binding proteins (2)
- RNA extraction (2)
- RNA helicase (2)
- RNA labeling (2)
- RNA metabolism (2)
- RNA modifications (2)
- RNA secondary structure (2)
- RNA structures (2)
- RNA synthesis (2)
- RNA virus (2)
- RNA-SEQ data (2)
- RNA-binding protein (2)
- RNA-dependent RNA polymerase (2)
- RNA-polymerase-II (2)
- RNS-Spleißen (2)
- RPE (2)
- RSK2 (2)
- RT-PCR (2)
- RT-qPCR (2)
- RYGB (2)
- Radarfernerkundung (2)
- Radiative-corrections (2)
- Radicals (2)
- Radio astronomy (2)
- Radioligand binding (2)
- Radionuclide Therapy (2)
- Raf kinases (2)
- Randomized controlled trial (2)
- Randomized controlled-trial (2)
- Rassismus (2)
- Raumfahrttechnik (2)
- Rauschgift (2)
- Reaction kinetics and dynamics (2)
- Real-time (2)
- Receptor (2)
- Rechnungswesen (2)
- Rectal cancer (2)
- Red Sea (2)
- Regenwald (2)
- Regionalentwicklung (2)
- Registrierung <Bildverarbeitung> (2)
- Regressionsanalyse (2)
- Regularisierung (2)
- Rehabilitation (2)
- Reinforcement Learning (2)
- Reinheitsanalytik (2)
- Relaxometry (2)
- Religion (2)
- Religionsunterricht (2)
- Religious Education (2)
- Religiöse Bildung (2)
- Renal cell carcinoma (2)
- Renin-Angiotensin-System (2)
- Renormierung (2)
- Repair (2)
- Repression <Genetik> (2)
- Reproductive toxicity (2)
- Reproduktion (2)
- Resilience (2)
- Resistance (2)
- Resource Management (2)
- Ressourcenallokation (2)
- Resveratrol (2)
- Retinoesäure (2)
- Rezeptor-Tyrosinkinasen (2)
- Rhabdomyosarcoma (2)
- Rheologie (2)
- Rheumatoide Arthritis (2)
- Rheumatologie (2)
- Rhizopus (2)
- Rho GTPase (2)
- Rho-Proteine (2)
- RhoA (2)
- Rhodobacter sphaeroides (2)
- Rhodopsin (2)
- Ribosome (2)
- Ribosome profiling (2)
- Riemann zeta-function (2)
- Riemannsche Zetafunktion (2)
- Riesenmagnetowiderstand (2)
- Risikomanagement (2)
- Risk factors (2)
- River Basins (2)
- Roboter (2)
- Rodents (2)
- Rotation (2)
- Ruxolitinib (2)
- Räumliche Verteilung (2)
- Räumliches Gedächtnis (2)
- Röntgen-Kleinwinkelstreuung (2)
- Röntgenabsorption (2)
- Röntgenabsorptionsspektroskopie (2)
- S-ADAPT (2)
- S. aureus (2)
- SAH (2)
- SARS‐CoV‐2 (2)
- SAS (2)
- SAXS (2)
- SEQ (2)
- SF-36 (2)
- SGLT2 inhibitor (2)
- SGLT2 inhibitors (2)
- SHRSP (2)
- SIM (2)
- SLAC1 (2)
- SLX4 (2)
- SMAD signaling (2)
- SNP (2)
- SOX9 (2)
- SPRED2 (2)
- SREBP (2)
- SSTR-RADS (2)
- STIM2 (2)
- STM (2)
- STR profile (2)
- SUN domain proteins (2)
- SUV (2)
- Sabah (2)
- Sahara (2)
- Salmonella-containing vacuole (SCV) (2)
- Salmonella/microsome assay (2)
- Salmonellosis (2)
- Samenverbreitung (2)
- Sand (2)
- Satellitenfernerkundung (2)
- Scale (2)
- Scaling (2)
- Scanning microscopy (2)
- Scheibe-Aggregat (2)
- Schilddrüse (2)
- Schilddrüsenkrebs (2)
- Schistosomiasis (2)
- Schizosaccharomyces pombe (2)
- Schlaf (2)
- Schlichte Funktion (2)
- Schnee (2)
- Schwamm (2)
- Schwann cell (2)
- Schwefelylide (2)
- Schwellenländer (2)
- Schwere-Fermionen-System (2)
- Schwermineral (2)
- Schwingungsphase (2)
- Schwingungsspektroskopie (2)
- Schädlingsbekämpfung (2)
- Screening (2)
- Segmentation (2)
- Segmentierung (2)
- Sehen (2)
- Selbstassoziation (2)
- Selective attention (2)
- Self-Aware Computing (2)
- Senescence (2)
- Senile Makuladegeneration (2)
- Sense of agency (2)
- Sensitivity (2)
- Sensors (2)
- Sepsis (2)
- Sequence Analysis (2)
- Sequenzanalyse (2)
- Serious game (2)
- Serotonin transporter (2)
- Sexuelle Selektion (2)
- Shigella (2)
- Shigella flexneri (2)
- Signaling (2)
- Silanole (2)
- Silicate (2)
- Siliciumdioxid (2)
- Silicon (2)
- Silicon carbide (2)
- Silicon-Boron Exchange (2)
- Silicones (2)
- Silizium-Boraustausch (2)
- Siliziumcarbid (2)
- Single Molecule Localization Microscopy (2)
- Single-molecule fluorescence microscopy (2)
- Sinne (2)
- Situation Awareness (2)
- Situationsbewusstsein (2)
- Skalierbarkeit (2)
- Smartphone (2)
- Smoking (2)
- Social VR (2)
- Social Virtual Reality (2)
- Social interaction (2)
- Software Performance Engineering (2)
- Softwareentwicklung (2)
- Sojabohne (2)
- Sol-Gel (2)
- Solution-state NMR (2)
- Somites (2)
- Sonic hedgehog (2)
- Soziale Mobilität (2)
- Soziale Vergleiche (2)
- Sozialität (2)
- Sozialphilosophie (2)
- Spectrin (2)
- Spermium (2)
- Spezifität (2)
- Spin defect (2)
- Spin density (2)
- Spin-Orbit Coupling (2)
- Spin-Orbit interaction (2)
- Spinal Muscular Atrophy (2)
- Spinchemie (2)
- Spinflüssigkeit (2)
- Spinsystem (2)
- Spivak, Gayatri Chakravorty (2)
- Sponges (2)
- Spred (2)
- Sprödbruch (2)
- Spumaviren (2)
- Squalius alburnoides (2)
- Stammzellen (2)
- Standardisierung (2)
- Staphylococcus epidermidis (2)
- Stat3 (2)
- State (2)
- State-Space Models (2)
- Stathmin (2)
- Statistische Mechanik (2)
- Statistische Physik (2)
- Stem cell (2)
- Stereology (2)
- Stereoselectivity (2)
- Stereotactic body radiotherapy (2)
- Sternentstehung (2)
- Steuerbarkeit (2)
- Stickstoffoxidsynthase (2)
- Stiffness (2)
- Stimuli (2)
- Stochastischer Prozess (2)
- Stofftransport <Biologie> (2)
- Strahlenpilze (2)
- Strains (2)
- Stratigraphy (2)
- Streaming <Kommunikationstechnik> (2)
- Streptomyces axinellae (2)
- Striatum (2)
- Stroma (2)
- Strongyloides stercoralis (2)
- Structural Equation Modeling (2)
- Structural elucidation (2)
- Struktur-Aktivitäts-Beziehung (2)
- Strömung (2)
- Subarachnoid hemorrhage (2)
- Succinylcholine (2)
- Sulfur Ylides (2)
- Super-Resolution Microscopy (2)
- Superconductivity (2)
- Superkondensator (2)
- Supernova (2)
- Supersaturation (2)
- Supply Chain (2)
- Supply Chain Design (2)
- Support Vector Machine (2)
- Supramolecular Chemistry (2)
- Surface states (2)
- Surveillance (2)
- Sustainability (2)
- Swine (2)
- Symmetriebrechung (2)
- Symmetry-breaking (2)
- Synapses (2)
- Synaptic plasticity (2)
- Synaptische Transmission (2)
- Synchronisation (2)
- Synchronisierung (2)
- Synchronization (2)
- Synchrotronstrahlung (2)
- System (2)
- Systematic review (2)
- Systemic sclerosis (2)
- Systemisches Risiko (2)
- Systems (2)
- Südafrika (2)
- Südostasien (2)
- T = 100 K (2)
- T cell development (2)
- T cell receptor excision circles (2)
- T-Zelle (2)
- T-Zellen (2)
- T-cadherin (2)
- T-cell epitope (2)
- T-cell lymphoma (2)
- TAVI (2)
- TB (2)
- TCR signaling cascade (2)
- TDDFT (2)
- TETCs (2)
- TFIIIC (2)
- TGF-BETA (2)
- TGF-ß (2)
- TGFβ signaling (2)
- TIMELINE (2)
- TKA (2)
- TLR2 (2)
- TLR3 (2)
- TMD (2)
- TNAP (2)
- TNF superfamily (2)
- TNFα (2)
- TRPA1 (2)
- TRRAP (2)
- TSN (2)
- Tamoxifen (2)
- TanDEM-X (2)
- Tandem-Massenspektrometrie (2)
- Tapeworm (2)
- Targeted therapies (2)
- Targeted therapy (2)
- Taxonomy (2)
- Technische Optik (2)
- Teilchenphysik (2)
- Teleoperation (2)
- Tell Jikan (2)
- Tell Karrana (2)
- Tell Khirbet Salih (2)
- Temozolomide (2)
- Termiten (2)
- Text Comprehension (2)
- Text mining (2)
- Textanalyse (2)
- Textual alterations weighting system (2)
- Textual document collation (2)
- Theoretical Computer Science (2)
- Theorie (2)
- Therapeutisches System (2)
- Thermodynamics (2)
- Thigmotaxis (2)
- Thiophen (2)
- Thioredoxin (2)
- Thrombo-inflammation (2)
- Thrombopoiesis (2)
- Tian Shan (2)
- Tiergesellschaft (2)
- Tillit (2)
- Time Series (2)
- Time Series Analysis (2)
- Time series analyses (2)
- Time-course (2)
- Timeless (2)
- Timing (2)
- Tissue (2)
- Titan (2)
- Titan-Saphir-Laser (2)
- Tomografie (2)
- Tonstein (2)
- Top-Quark (2)
- Topological Insulators (2)
- Topologische Isolatoren (2)
- Toxicology (2)
- TraDIS (2)
- Training (2)
- Tranquillizer (2)
- Transaktivierung (2)
- Transcription factor (2)
- Transfer (2)
- Transition metals (2)
- Translation (2)
- Translational research (2)
- Translokation (2)
- Transporteigenschaft (2)
- Transporter (2)
- Trauma (2)
- Travelling-salesman-Problem (2)
- Trees (2)
- Tregs (2)
- Tregs (regulatory T cells) (2)
- Triarylamin (2)
- Triquinacenderivate (2)
- Trockenstress (2)
- Tropischer Regenwald (2)
- Trunkenheit im Verkehr (2)
- Trust (2)
- Trypanosoma brucei brucei (2)
- Trypanosomiase (2)
- Tryptophan (2)
- Tsetsefliege (2)
- Tubulin (2)
- Tumor Treating Fields (TTFields) (2)
- Tumor-Nekrose-Faktor (2)
- Tumorimmunologie (2)
- Tumors (2)
- Turbulenz (2)
- Type 1 Diabetes (2)
- Type 1 diabetes (2)
- UTI (2)
- Ubiquitin-Protein-Ligase (2)
- Uganda (2)
- Ulcerative colitis (2)
- Ultimatum Game (2)
- Ultrafast Spectroscopy (2)
- Ultrafast information processing (2)
- Umverteilung (2)
- Umwelt (2)
- Umweltpolitik (2)
- Uncertainty (2)
- Unconventional/Topological superconductivity (2)
- Unmanned Aerial Vehicle (UAV) (2)
- Unternehmensbewertung (2)
- Unternehmenskooperation (2)
- Unterrichtspsychologie (2)
- Urämie (2)
- User Interface (2)
- Ustilago maydis (2)
- Uzbekistan (2)
- VACV (2)
- VAL66MET polymorphism (2)
- VLA-1 (2)
- VMD2 (2)
- VSOP (2)
- Vacuum stability (2)
- Valeriana wallichii (2)
- Validierung (2)
- Validität (2)
- Value (2)
- Variability (2)
- Variant surface glycoprotein (2)
- Varroa destructor (2)
- Vascular endothelial Growth Factor (2)
- Vaskularisation (2)
- Vaskularisierung (2)
- Vasopressin (2)
- Vegetation (2)
- Vektorboson (2)
- Venus (2)
- Verallgemeinertes Nash-Gleichgewichtsproblem (2)
- Verbindungen (2)
- Verbindungshalbleiter (2)
- Verbotsmuster (2)
- Vereisung (2)
- Vergleichende politische Wissenschaft (2)
- Verhaltensanalyse (2)
- Verhaltensforschung (2)
- Verhaltenskontrolle (2)
- Vermeidungsreaktion (2)
- Verschränkung (2)
- Verspannung (2)
- Verstärkung (2)
- Verteidigung (2)
- Vertrauen (2)
- Vesicles (2)
- Vesikel (2)
- Videospiel (2)
- Vielteilchensystem (2)
- Vierwellenmischung (2)
- Virchow Node (2)
- Viren (2)
- Virology (2)
- Virotherapy (2)
- Virus (2)
- Viskosität (2)
- Visuelle Wahrnehmung (2)
- Vorhersage (2)
- Vorschulkind (2)
- WH2 domain (2)
- WSS (2)
- WZ (2)
- Wachs (2)
- Wachstumsfaktor (2)
- Wachstumsprozess (2)
- Wahrscheinlichkeitstheorie (2)
- Warteschlangentheorie (2)
- Wasserstoffbrückenbindung (2)
- Wasserstoffperoxid (2)
- Wechselkurspolitik (2)
- Wechselwirkung (2)
- Weißer Zwerg (2)
- Wellenleiter (2)
- Werbung (2)
- West Gondwana (2)
- Western Cape (2)
- Western Europe (2)
- Western diet (2)
- Wettbewerb (2)
- Wettbewerbsstrategie (2)
- Weyl semimetals (2)
- Wildbienen (2)
- Wilms tumour (2)
- Winterweizen (2)
- Wirbellose (2)
- Wirt-Gast-Beziehung (2)
- Wirtschaftsentwicklung (2)
- Wirtschaftswachstum (2)
- Wissenserwerb (2)
- Wnt (2)
- Wnt signalling (2)
- Wohlbefinden (2)
- Wolframkomplexe (2)
- Wrapper <Programmierung> (2)
- Würzburg / Sonderforschungsbereich II-VI-Halbleiter (2)
- Würzburg / Universität / Lehrstuhl für Bioinformatik (2)
- X-ray Crystallography (2)
- X-ray computed (2)
- X-ray diffraction (2)
- X-ray microscopy (2)
- XAI (2)
- XES (2)
- XIAP (2)
- XLH (2)
- XMCD (2)
- XNA (2)
- XR (2)
- Xenopus oocytes (2)
- Yersinia (2)
- Yersinia enterocolitica (2)
- Yoga (2)
- YouTube (2)
- Z Boson (2)
- Zahlentheorie (2)
- Zambia (2)
- Zea mays (2)
- Zebrafisch (2)
- Zeitaufgelöste Spektroskopie (2)
- Zeitauflösung (2)
- Zeitrichtung (2)
- Zelloberfläche (2)
- Zement (2)
- Zerfall (2)
- Zirkulardichroismus Spektroskopie (2)
- ZnO (2)
- ZnSe (2)
- Zucker (2)
- Zustandsraummodelle (2)
- Zuverlässigkeit (2)
- Zwei-Prozess-Modell (2)
- Zweidimensionale konforme Feldtheorie (2)
- Zweidimensionales Material (2)
- Zweiphotonenabsorption (2)
- Zweisprachigkeit (2)
- Zwergfadenwurm (2)
- Zwischenmolekulare Kraft (2)
- Zypern (2)
- Zytoskelett (2)
- [177Lu]-DOTATATE/-DOTATOC (2)
- [68Ga] (2)
- [68Ga]PentixaFor (2)
- ab interno trabeculectomy (2)
- ablation (2)
- abscisic acid (2)
- abscisic acid (ABA) (2)
- absorption spectra (2)
- abundance (2)
- academic achievement (2)
- acceptance (2)
- acceptance time efficiency (2)
- accessibility (2)
- accretion (2)
- acetylsalicylic acid (2)
- acid ceramidase inhibitor ceranib-2 (2)
- acoustic signals (2)
- acoustic startle (2)
- action control (2)
- action effects (2)
- action planning (2)
- action potentials (2)
- active ingredients (2)
- activity (2)
- activity rhythm (2)
- acupuncture (2)
- acute graft-versus-host disease (2)
- acute heart failure (2)
- acute lymphoblastic leukemia (2)
- acute myeloid leukaemia (2)
- adaptive optimization (2)
- addiction (2)
- adenocarcinoma (2)
- adenomas (2)
- adenosine receptors (2)
- adenovirus (2)
- adenylate cyclase toxin (2)
- adhesion molecules (2)
- adipogenic differentiation (2)
- adjustment (2)
- adjuvant treatment (2)
- adolescent (2)
- adoptive transfer (2)
- adrenal cancer (2)
- adrenal crisis (2)
- adrenal gland (2)
- adrenal incidentaloma (2)
- adrenal tumours (2)
- adrenocortical adenoma (2)
- adrenocortical tumors (2)
- adult (2)
- adult neurogenesis (2)
- adult-onset (2)
- adulthood (2)
- adverse drug reaction (2)
- adverse effects (2)
- adversity (2)
- age-related hearing loss (2)
- aged 80 and over (2)
- agonistic antibodies (2)
- agreement (2)
- agrobacterium tumefaciens (2)
- agroecosystems (2)
- airway management (2)
- albumin (2)
- aldehydes (2)
- alleles (2)
- allelic replacement (2)
- allergic rhinitis (2)
- alliance (2)
- allogeneic hematopoietic stem cell transplantation (2)
- allografts (2)
- allometric scaling (2)
- alloreactive T cells (2)
- allostatic load (2)
- alpaca (2)
- alpha (2)
- altruism (2)
- altruistic compensation (2)
- alveolar bone loss (2)
- alveolar echinococcosis (2)
- amino acid restriction (2)
- amino acid sequence (2)
- amino acid transporter (2)
- aminotroponiminates (2)
- ammonites (2)
- ammonium permease (2)
- ampicillin (2)
- amplicon sequencing (2)
- amyloid beta (2)
- amyotrophic lateral sclerosis (ALS) (2)
- anaesthesiology (2)
- anaesthetics (2)
- analgesia (2)
- analysis (2)
- anaphylaxis (2)
- anaplastic large cell lymphoma (2)
- anchoring (2)
- androgen deprivation therapy (2)
- anesthetics (2)
- angle-resolved photoemission spectroscopy (2)
- anhedonia (2)
- anion channel (2)
- anions (2)
- anisotropy (2)
- annulation (2)
- anomaly detection (2)
- ant (2)
- ant brain (2)
- antenna (2)
- anterior cingulate cortex (2)
- anti-infective (2)
- anti-k jet (2)
- anti-parasitic (2)
- anti-protease (2)
- anti-trypanosomal (2)
- anti-tumor agents (2)
- antibody fusion proteins (2)
- anticancer activity (2)
- antigen presentation (2)
- antigens (2)
- antileishmanial (2)
- antimicrobial activities (2)
- antimicrobial activity (2)
- antioxidant (2)
- antirheumatic agents (2)
- antisense RNAs (2)
- antiviral treatment (2)
- anxiety-like behavior (2)
- aortic arch (2)
- aphasia (2)
- app (2)
- approach-avoidance (2)
- arabidopsis (2)
- archaea (2)
- areas (2)
- artemisinin (2)
- arteriovenous loop (2)
- articular chondrocytes (2)
- artifacts (2)
- artificial diet (2)
- ascites (2)
- aspiration (2)
- assay (2)
- assembly (2)
- assistive devices (2)
- astrophysics (2)
- asymmetry (2)
- atmospheric chemistry (2)
- atmospheric circulation (2)
- atomic force microscopy (2)
- atomic-force microscopy (2)
- atopic diseases (2)
- attention capture (2)
- attentional bias (2)
- audit fees (2)
- auditory cortex (2)
- augmented Lagrangian method (2)
- autobiographical memory (2)
- autoimmune (2)
- autoinhibition (2)
- autologous stem cell transplantation (2)
- autologous transplantation (2)
- autonomous (2)
- auxins (2)
- avatar embodiment (2)
- avoidance (2)
- avoidance learning (2)
- awareness (2)
- axon growth (2)
- axonal degeneration (2)
- axonal transport (2)
- azulene (2)
- bZIP (2)
- background (2)
- background knowledge (2)
- baclofen (2)
- bacterial (2)
- bacterial genetics (2)
- bacterial genomics (2)
- bacteriology (2)
- baghdadite (2)
- band structure (2)
- barbiturates (2)
- barrier (2)
- base of support (2)
- basic mental models (2)
- bats (2)
- beech forests (2)
- behavioral plasticity (2)
- behavioral rhythms (2)
- beige adipocytes (2)
- benzimidazole (2)
- beta oscillations (2)
- beta-catenin (2)
- beta-glucuronidase (2)
- beta-oxidation (2)
- bias correction (2)
- biased signaling (2)
- big five (2)
- bile (2)
- binding sites (2)
- binge eating (2)
- biodosimetry (2)
- bioengineering (2)
- biofeedback (2)
- biofilm (2)
- biofilm formation (2)
- biogenesis (2)
- bioimage analysis (2)
- bioinformatic (2)
- bioisosterism (2)
- biological activity (2)
- biological sciences (2)
- biological techniques (2)
- biomedical applications (2)
- biomedicine (2)
- biomedicine, general (2)
- biosensor (2)
- biradicals (2)
- bisphosphonates (2)
- bisulfite pyrosequencing (2)
- bitter taste (2)
- black lipid bilayer (2)
- blastocysts (2)
- blazar (2)
- blazars (2)
- bleeding (2)
- blended learning (2)
- blood coagulation (2)
- blood gas analysis (2)
- blood nerve barrier (2)
- blood platelets (2)
- blood-brain barrier (BBB) model (2)
- blood-nerve barrier (2)
- blood-stream forms (2)
- blood–labyrinth barrier (2)
- body ownership (2)
- body representation (2)
- body weight modification (2)
- body weight perception (2)
- bonding (2)
- bone adhesive (2)
- bone formation (2)
- bone fractures (2)
- bone imaging (2)
- bone loss (2)
- bone marrow edema (2)
- bone marrow immune-microenvironment (2)
- bone marrow stromal cells (2)
- bone marrow transplantation (2)
- bone metabolism (2)
- bone metastasis (2)
- bone morphogenetic protein (2)
- bone remodeling (2)
- bone replacement material (2)
- boronateesters (2)
- boronates (2)
- boronic acid (2)
- bortezomib (2)
- borylene complexes (2)
- brain disorders (2)
- brain edema (2)
- brain endothelial cells (2)
- brain metastases (2)
- brain pathology (2)
- brain potentials (2)
- brain stem (2)
- brain-computer interface (BCI) (2)
- brain-computer interfaces (2)
- breed predisposition (2)
- bridging (2)
- brucei (2)
- building behavior (2)
- buildings (2)
- bullous pemphigoid (2)
- butyrophilin (2)
- butyrophilin 3 (2)
- butyrylcholinesterase (2)
- c-MYC (2)
- c-reactive protein (2)
- cAArC (2)
- cEND (2)
- cadherins (2)
- caenorhabditis elegans (2)
- caffeine (2)
- cage compounds (2)
- calcium imaging (2)
- calcium signaling (2)
- calibration (2)
- calipered (2)
- calorie content (2)
- calorimeter (2)
- calpain (2)
- calprotectin (2)
- calyx (2)
- cancer detection and diagnosis (2)
- cancer diagnosis (2)
- cancer microenvironment (2)
- cancer risk (2)
- cancer risk factors (2)
- cancers and neoplasms (2)
- candida albicans (2)
- candidate gene (2)
- candidate genes (2)
- candidemia (2)
- canine (2)
- canine cancer cell lines (2)
- canine soft tissue sarcoma (CSTS) (2)
- capacitance (2)
- capacity (2)
- carabid beetles (2)
- carbon (2)
- carbon monoxide (2)
- carbon nanotubes (2)
- carborane (2)
- carboxylation (2)
- carcinogen (2)
- carcinogenesis (2)
- carcinogenicity (2)
- carcinoma cells (2)
- cardiac MRI (2)
- cardiac imaging (2)
- cardiac innervation imaging (2)
- cardiac magnetic resonance (2)
- cardiac nerve (2)
- cardiac output (2)
- cardiac rehabilitation (2)
- cardinality constraints (2)
- cardiology (2)
- cardioprotection (2)
- cardiovascular arousal (2)
- cardiovascular morbidity (2)
- caregiver burden (2)
- caries (2)
- carnivorous plants (2)
- carotid atherosclerosis (2)
- carotid stenosis (2)
- carotid ultrasound (2)
- carpenter ant (2)
- cartilage repair (2)
- caspase-8 (2)
- catalytic (2)
- cathepsin (2)
- causality (2)
- cell binding assay (2)
- cell cycle arrest (2)
- cell division (2)
- cell fate (2)
- cell growth (2)
- cell metabolism (2)
- cell of origin (2)
- cell signalling (2)
- cell surface (2)
- cell-based therapy (2)
- cellular physiology (2)
- cellular signalling networks (2)
- cement (2)
- ceramics (2)
- cerebEND (2)
- cerebral autoregulation (2)
- cerebral blood flow (2)
- cerebrosides (2)
- change vector analysis (2)
- channel (2)
- chaperones (2)
- characterization (2)
- charge carrier generation (2)
- charge density (2)
- checkpoint inhibitors (2)
- chemical bonding (2)
- chemical crosslinking (2)
- chemical mimicry (2)
- chemokine (2)
- chemotaxis (2)
- child (2)
- child development (2)
- childhood (2)
- childhood asthma (2)
- childhood cancer (2)
- childhood maltreatment (2)
- chiral (2)
- chiral separation (2)
- chirality transfer (2)
- chloroquine (2)
- cholestasis (2)
- cholesterol (2)
- cholinergic system (2)
- chromatin structure (2)
- chromosomes (2)
- chronic cerebrovascular disease (2)
- chronic hepatitis C (2)
- chronic kidney-disease (2)
- chronic myelogenous leukemia (2)
- chronic myeloid leukemia (2)
- chronic non-bacterial osteomyelitis (2)
- chronic nonbacterial osteomyelitis (2)
- chronic recurrent multifocal osteomyelitis (2)
- chronic thromboembolic pulmonary hypertension (2)
- chronobiology (2)
- chronophin (2)
- chronotype (2)
- church (2)
- cigarette smoking (2)
- circulation patterns (2)
- circulation type (2)
- cirrhosis (2)
- claudin-1 (2)
- clinical (2)
- clinical diagnosis (2)
- clinical outcome (2)
- clinical-practice (2)
- clothing (2)
- cluster analysis (2)
- clustering (2)
- coastal erosion (2)
- coated vesicles (2)
- coating (2)
- coatings (2)
- cochlear nucleus (2)
- coevolution (2)
- cofilin (2)
- cognitive bias (2)
- cognitive conflict (2)
- cognitive function (2)
- cognitive neuroscience (2)
- cognitive psychology (2)
- cognitive-behavioral therapy (2)
- cohort study (2)
- cold stress (2)
- colloids (2)
- collybistin (2)
- colon (2)
- colon cancer (2)
- colonization (2)
- color vision (2)
- colorectal carcinoma (2)
- combined therapy (2)
- common variants (2)
- communication networks (2)
- communities (2)
- community composition (2)
- community structure (2)
- comorbidity (2)
- comparability (2)
- comparative genomic hybridization (2)
- complement system (2)
- complementary alternative medicine (2)
- complementary medicine (2)
- complex regional pain syndrome (2)
- complexation (2)
- complication (2)
- component (2)
- components (2)
- composites (2)
- compound eye (2)
- compressive strength (2)
- computational biology and bioinformatics (2)
- computational physics (2)
- computer software (2)
- cone beam CT (2)
- confidence interval (2)
- confocal microscopy (2)
- conjugated polymers (2)
- connected mobility applications (2)
- connective tissue (2)
- consensus (2)
- conservation biology (2)
- conservation laws (2)
- consolidation (2)
- conspicuous consumption (2)
- constitution (2)
- contact-kinin system (2)
- contextual fear conditioning (2)
- contrast (2)
- control (2)
- convection volume (2)
- conversational agents (2)
- cool-season grass species (2)
- cooperativity (2)
- coordination polymers (2)
- copeptin (2)
- corannulene (2)
- cord blood (2)
- corneal confocal microscopy (2)
- coronavirus disease 2019 (2)
- correlates (2)
- cortex (2)
- cortical activation (2)
- cortical neurons (2)
- cosmic rays (2)
- cost-effectiveness (2)
- costs (2)
- coupling strength (2)
- covalent inhibitors (2)
- craving (2)
- creatine kinase (2)
- creatinine (2)
- creativity (2)
- cristae (2)
- crop yield (2)
- cropping systems (2)
- cross-cultural comparison (2)
- cross-link repair (2)
- cross-modal action (2)
- cross-sectional studies (2)
- crystal engineering (2)
- crystal growth (2)
- crystal-structure (2)
- cultivation (2)
- cultural politics (2)
- cultural theory (2)
- cultures (2)
- curcumin (2)
- curved hydrocarbons (2)
- cuticle (2)
- cyanoborate (2)
- cyanoborates (2)
- cybersickness (2)
- cycle (2)
- cyclic (alkyl)(amino)carbenes (2)
- cycling (2)
- cyclodextrin (2)
- cyclophane (2)
- cyclophanes (2)
- cystic fibrosis patients (2)
- cytochrome P450 3A4 (CYP3A4) (2)
- cytokine production (2)
- cytokine release (2)
- cytokine secretion (2)
- cytomegalovirus (2)
- cytosolic pH (2)
- cytotoxic (2)
- cytotoxic activity (2)
- dCIRL (2)
- dRNA-Seq (2)
- daratumumab (2)
- dark matter (2)
- data (2)
- data analysis (2)
- data mining (2)
- data visualization (2)
- data warehouse (2)
- ddPCR (2)
- death (2)
- death rates (2)
- decidability (2)
- decline (2)
- defense (2)
- deficit hyperactivity disorder (2)
- degree of stenosis (2)
- deletion (2)
- delineation (2)
- demography (2)
- dendritische Zellen (2)
- dendrobates pumilio (2)
- dental trauma (2)
- dependent protein-kinase (2)
- dereplication (2)
- derivation (2)
- dermatitis (2)
- desirable difficulties (2)
- desk-based (2)
- desmosome (2)
- detection (2)
- deubiquitinase (2)
- developmental dyslexia (2)
- developmental plasticity (2)
- dexamethasone suppression test (2)
- diabetic cardiomyopathy (2)
- diabetic retinopathy (2)
- diagnostic (2)
- dialysis adequacy (2)
- diapause (2)
- diastolic dysfunction (2)
- diazadiborinines (2)
- dictator game (2)
- dieting success (2)
- differential diagnosis (2)
- differential expression (2)
- differentiation potential (2)
- diffuse large B-cell lymphoma (2)
- diffusion tensor imaging (2)
- digit (2)
- digital change (2)
- digital health (2)
- digitalization (2)
- dimensions (2)
- dimer (2)
- dimethyl fumarate (2)
- diode (2)
- diradicals (2)
- direct anterior approach (2)
- direct gaze (2)
- direct-acting antivirals (2)
- discovery (2)
- discriminant analysis (2)
- discrimination training (2)
- discussion report (2)
- disease model (2)
- disease modelling (2)
- diseases of the nervous system (2)
- disembodiment (2)
- disengagement (2)
- disfluency (2)
- disorders (2)
- dispersal ability (2)
- dispersal distance (2)
- dispersal rate (2)
- distance (2)
- distance measurement (2)
- distress (2)
- distributed control (2)
- disturbance (2)
- disulfide bonds (2)
- dog (2)
- dopaminergics (2)
- doping (2)
- dorsal root ganglion (2)
- dorsolateral prefrontal cortex (2)
- dot-depth problem (2)
- double intentionality (2)
- doxorubicin (2)
- drought stress (2)
- drug release (2)
- drug–drug interactions (DDIs) (2)
- dual function (2)
- dual polarimetry (2)
- dual setting (2)
- dual setting system (2)
- dual-energy CT (2)
- dual-stage crosslinking (2)
- dualsteric ligands (2)
- duchenne muscular dystrophy (2)
- dunce (2)
- duplication (2)
- dynamic (2)
- dynamic covalent chemistry (2)
- dysfunction (2)
- dysphagia (2)
- dysplasia (2)
- dyspnea (2)
- e-learning (2)
- early detection (2)
- early diagnosis (2)
- early intervention (2)
- early recognition (2)
- early-life stress (2)
- echinococcus multilocularis (2)
- economics (2)
- edema (2)
- edge states (2)
- editorial board (2)
- education for sustainable healthcare (2)
- educational tool (2)
- effectiveness (2)
- effects (2)
- efflux pumps (2)
- elbow joint (2)
- electroactive (2)
- electrocatalysis (2)
- electrochromic device (2)
- electroencephalography (EEG) (2)
- electrolytes (2)
- electromyography (2)
- electron density distribution (2)
- electronic health records (2)
- electrophilic substitution (2)
- electroporation (2)
- element (2)
- elements (2)
- elevation gradient (2)
- elevational gradients (2)
- elongation (2)
- embryo (2)
- emergent time (2)
- emissions (2)
- emotion recognition (2)
- emotional experience (2)
- emotional facial expressions (2)
- emotional pictures (2)
- empagliflozin (2)
- emulsions (2)
- enantiomers (2)
- encephalitis (2)
- endliche Automaten (2)
- endocannabinoid (2)
- endochondral ossification (2)
- endoglin (2)
- endoluminal (2)
- endophenotype (2)
- endoplasmic reticulum (2)
- endosomal trafficking (2)
- endosomes (2)
- endothelial cell (2)
- endothelial progenitor cells (2)
- endothelin-1 (2)
- endotoxemia (2)
- endovascular therapy (2)
- endovascular treatment (2)
- energy homeostasis (2)
- enteric nervous system (2)
- enteric pathogens (2)
- enterica serovar typhimurium (2)
- entrepreneurship (2)
- entropy minimization (2)
- envelopment (2)
- environmental exposure (2)
- environmental filtering (2)
- environmental impact (2)
- environmental justice (2)
- environments (2)
- enzyme activation (2)
- enzyme inhibitors (2)
- epidemology (2)
- epidermal growth factor (2)
- epidermal growth factor receptor (2)
- epithelium (2)
- epitope mapping (2)
- epitranscriptomics (2)
- erythropoietin (2)
- establishment (2)
- estimation error (2)
- estrogen (2)
- ethics (2)
- etiology (2)
- etymology (2)
- eudaimonia (2)
- eugenol (2)
- evapotranspiration (2)
- event-related potential (2)
- evolutionary biology (2)
- evolutionary genetics (2)
- exact matching (2)
- excimer formation (2)
- excitations (2)
- exciton-exciton (2)
- exciton-polariton (2)
- exercise intervention (2)
- exhaustion (2)
- exocytosis (2)
- expansion microscopy (2)
- experiment (2)
- experimental models of disease (2)
- experimental physics (2)
- expertise (2)
- explosive volcanism (2)
- expression signature (2)
- extinction dynamics (2)
- extinction risk (2)
- extracellular domain (2)
- extramedullary disease (2)
- extreme value distribution (2)
- fMRI time series (2)
- fMRT (2)
- fabry disease (2)
- face recognition (2)
- facial electromyography (2)
- factor H (2)
- factor XI (2)
- factor-I (2)
- failure (2)
- fake lepton (2)
- familial DCM (2)
- families (2)
- fast vollständig zerlegbare Gruppe (2)
- fatty acid (2)
- fatty acid biosynthesis (2)
- fatty liver (2)
- fear-potentiated startle (2)
- feasibility (2)
- feature selection (2)
- features (2)
- femtochemistry (2)
- femur (2)
- fermentation (2)
- fermions (2)
- ferroelectricity (2)
- ferromagnetic semiconductors (2)
- ferromagnetism (2)
- fetal programming (2)
- fibers (2)
- fibrinogen (2)
- fibroblast activation protein (2)
- fibromyalgia (2)
- field (2)
- films (2)
- finite automata (2)
- finite elements (2)
- fire (2)
- fission yeast (2)
- fixation (2)
- flagellar pocket (2)
- flatworm (2)
- flood (2)
- flow (2)
- flowering plants (2)
- fluid (2)
- fluorescence correlation spectroscopy (2)
- fluorescence resonance energy transfer (FRET) (2)
- fluorescent dyes (2)
- fluorescent probe (2)
- fluorescent proteins (2)
- fluorescent-probes (2)
- fluoroscopy (2)
- flupyradifurone (2)
- flux balance analysis (2)
- foamy virus (2)
- foamy viruses (2)
- focal cerebral-ischemia (2)
- fog computing (2)
- follicular lymphoma (2)
- food (2)
- food addiction (2)
- food allergy (2)
- food consumption (2)
- food craving (2)
- food safety (2)
- foot (2)
- forager (2)
- foraging behavior (2)
- forbidden patterns (2)
- forecast (2)
- forensic anthropology (2)
- forest conservation (2)
- forest degradation (2)
- forest health (2)
- forests (2)
- formation control (2)
- fpVCT (2)
- fracture healing (2)
- framework (2)
- framing (2)
- free choice (2)
- free electron laser (2)
- free energy (2)
- free fatty acids (2)
- freezing of gait (2)
- frontal cortex (2)
- fruit (2)
- fruit set (2)
- functional MRI (2)
- functional analysis (2)
- functional connectivity (2)
- functional imaging (2)
- functional modules (2)
- functional neuroimaging (2)
- functional renormalization group (2)
- functional traits (2)
- functionalization (2)
- fungal infections (2)
- funktionelle Kernspintomographie (2)
- furan (2)
- fused deposition modeling (FDM) (2)
- fusion and fission (2)
- future directions (2)
- g-Tensor (2)
- g-tensor (2)
- gain (2)
- galectin-1 (2)
- gambling (2)
- gamma (2)
- gamma astronomy (2)
- gas (2)
- gastric bypass (2)
- gastrointestinal cancer (2)
- gastrointestinal infection (2)
- gastrointestinal infections (2)
- gekrümmte Kohlenwasserstoffe (2)
- gels (2)
- gemcitabine (2)
- gene cloning (2)
- gene conversion (2)
- gene expression profiling (2)
- gene mutations (2)
- gene-environment interaction (2)
- geneexpression (2)
- general anaesthesia (2)
- general practice (2)
- general relativity (2)
- generalization (2)
- generalized Pareto distribution (2)
- generalized anxiety disorder (2)
- generalized cerebral edema (2)
- generation effect (2)
- genetic architecture (2)
- genetic diagnostics (2)
- genetic engineering (2)
- genetic modification (2)
- genetic polymorphisms (2)
- genetic screen (2)
- genetic susceptibility (2)
- genetic testing (2)
- genetic variants (2)
- genetically modified plants (2)
- genome analysis (2)
- genome sequencing (2)
- genome wide (2)
- genome-wide association study (2)
- genomic analysis (2)
- genomic databases (2)
- genomic imaging (2)
- genomic imprinting (2)
- genomic libraries (2)
- geoarcheology (2)
- geometry (2)
- geophysical prospection (2)
- geophysics (2)
- germline mutation (2)
- gestational diabetes mellitus (2)
- giant ventral hernia (2)
- glial fate modulation (2)
- glioblastoma multiforme (GBM) (2)
- global convergence (2)
- globotriaosylceramide (2)
- glucose metabolism (2)
- glutathione (2)
- glycemic control (2)
- glycine (2)
- glycine receptor autoantibodies (2)
- glycopeptide antibiotics (2)
- glycoprotein Ib (2)
- glycoprotein receptor Ib (2)
- glycosylation (2)
- go/no-go task (2)
- gold (2)
- gold nanoparticles (2)
- gonad development (2)
- gp130 (2)
- grading (2)
- graft (2)
- graft versus host disease (2)
- gram-negative bacteria (2)
- grammar (2)
- granules (2)
- granulocytes (2)
- granzyme B (2)
- graphs (2)
- grassland (2)
- grasslands (2)
- gravitational waves (2)
- green fluorescent protein (2)
- gridle muscular-dystrophy (2)
- groundwater (2)
- growth factor beta (2)
- growth hormone deficiency (2)
- guanylyl cyclase (2)
- guided bone regeneration (2)
- gut bacteria (2)
- gut barrier (2)
- gynogenesis (2)
- gyroscope (2)
- habitat (2)
- habits (2)
- haemodialysis (2)
- haemophilus influenzae (2)
- halogenation (2)
- hand (2)
- hangover (2)
- haploinsufficiency (2)
- harmonization (2)
- head and neck squamous cell carcinoma (2)
- head-mounted display (2)
- health (2)
- health care (2)
- health care workers (2)
- health economics (2)
- health monitoring (2)
- health policy (2)
- hearing impairment (2)
- hearing preservation (2)
- heart failure with mid-range ejection fraction (2)
- heart rate variability (2)
- heat shock response (2)
- heat stress (2)
- helical edge states (2)
- helicase (2)
- helicene (2)
- helicenes (2)
- hematologic malignancies (2)
- hematopoiesis (2)
- hematopoietic (2)
- hematopoietic stem cell transplantation (2)
- heme oxygenase-1 (2)
- hemicraniectomy (2)
- hemodiafiltration (2)
- hepatic stellate cell (2)
- hepatocellular carcinoma (2)
- hepatotoxicity (2)
- herbivore (2)
- hereditary breast and ovarian cancer (2)
- hereditary motor and sensory neuropathy (2)
- herpes simplex virus (2)
- herpes virus (2)
- heterogeneity (2)
- heterogeneous catalysis (2)
- heterosis (2)
- heuristics (2)
- hiPSC (2)
- hierarchy (2)
- high contrast (2)
- high performance liquid chromatography (2)
- high risk (2)
- high-risk prostate cancer (2)
- high-throughput screening (2)
- hip fracture (2)
- hippocampal neurogenesis (2)
- histamine (2)
- histopathology (2)
- history (2)
- holography and condensed matter physics (AdS/CMT) (2)
- homocysteine (2)
- homogenous catalysis (2)
- homologous chromosomes (2)
- hormones (2)
- hospital (2)
- hospitalizations (2)
- human adipose-derived stromal cells (2)
- human african trypanosomiasis (2)
- human breast (2)
- human cells (2)
- human cytomegalovirus (HCMV) (2)
- human exposure (2)
- human genetics (2)
- human induced pluripotent stem cells (2)
- human interleukin-4 (2)
- human macrophages (2)
- human pathogenic fungi (2)
- human plasma (2)
- human rights (2)
- human-centered design (2)
- hybrid polymers (2)
- hybridogenesis (2)
- hybridomas (2)
- hydration dynamics (2)
- hydrocarbons (2)
- hydrocortisone (2)
- hydrogen (2)
- hydrogenation (2)
- hydrogeology (2)
- hydrological modelling (2)
- hyperactivity (2)
- hyperalgesia (2)
- hypercholesterolemia (2)
- hyperoxia (2)
- hypersensitivity (2)
- hyphae (2)
- hypogammaglobulinemia (2)
- hypothalamus (2)
- hypotonic (2)
- iNOS (2)
- iPSC-cardiomyocytes (2)
- iPSCs (2)
- idiopathic inflammatory myopathies (2)
- ileocecal resection (2)
- illness (2)
- image analysis (2)
- image quality (2)
- image-guided radiation therapy (2)
- imaging the immune system (2)
- imidazolate (2)
- immune cell infiltration (2)
- immune genes (2)
- immune reconstitution (2)
- immune suppression (2)
- immune therapy (2)
- immunoassay (2)
- immunoblotting (2)
- immunodeficiency (2)
- immunoglobulin superfamily (2)
- immunostaining (2)
- immunosurveillance (2)
- implant positioning (2)
- implantation (2)
- implants (2)
- in silico analysis (2)
- in situ hybridization (2)
- in vitro models (2)
- inactivation (2)
- incentives (2)
- individual‐based model (2)
- inebilizumab (2)
- infarction (2)
- infection biology (2)
- infection control (2)
- infection rates (2)
- inferior vena cava (2)
- inflammatory cytokines (2)
- inflammatory neuropathy (2)
- inflammatory response (2)
- informal caregiving (2)
- infrared (2)
- infrared-spectra (2)
- inhibitory neurotransmission (2)
- inhibitory postsynapse (2)
- injury prevention (2)
- innate immune system (2)
- inner ear (2)
- insect decline (2)
- insect flight (2)
- insect immunity (2)
- insect monitoring (2)
- insect vision (2)
- insecticide (2)
- insecticides (2)
- insertion (2)
- insights (2)
- insulin signaling (2)
- integral (2)
- integrated stress response (2)
- intellectual disability (2)
- intensity zones (2)
- interacts (2)
- interband cascade lasers (2)
- interferometry (2)
- interleukin 6 (2)
- interleukin-8 (2)
- intermanual transfer (2)
- intermanueller Transfer (2)
- intermolecular interaction (2)
- internal medicine (2)
- internal transcribed spacer 2 (2)
- internalization (2)
- international trade (2)
- internationalism (2)
- internet of things (2)
- interpolation (2)
- interval timing (2)
- interval training (2)
- intervalence charge transfer (2)
- intestinal barrier (2)
- intestinal in vitro model (2)
- intestinal mucus (2)
- intestinal permeability (2)
- intracellular bacterial pathogens (2)
- intracellular membranes (2)
- intracellular pathogens (2)
- intraoperative imaging (2)
- introgressive hybridization (2)
- intrusion detection (2)
- invasive fungal infection (2)
- invasive fungal infections (2)
- ionizing radiation (2)
- ipilimumab (2)
- ischaemic stroke (2)
- ischemia reperfusion injury (2)
- ischemia-reperfusion injury (2)
- ischemia/reperfusion injury (2)
- ischemic penumbra (2)
- island biogeography (2)
- islet transplantation (2)
- isocenter (2)
- isolation (2)
- isomerization (2)
- isothermal titration calorimetry (2)
- isotonic (2)
- jet channel (2)
- jet reconstruction efficiency (2)
- jet transverse momentum (2)
- jitter (2)
- joint aspiration (2)
- joint instability (2)
- judgements (2)
- judgments (2)
- jump-diffusion processes (2)
- keratinocytes (2)
- kidney cancer (2)
- kidney disease (2)
- kinase inhibitors (2)
- knee osteoarthritis (2)
- knee replacement (2)
- knowledge acquisition (2)
- knowledge engineering (2)
- knowledge representation (2)
- knowledge-based systems (2)
- laboratory techniques and procedures (2)
- lactate dehydrogenase (2)
- lactation (2)
- land surface (2)
- land surface temperature (2)
- land use intensification (2)
- land-use intensity (2)
- landsat (2)
- landscape (2)
- landscape heterogeneity (2)
- landscape metrics (2)
- landscape structure (2)
- language acquisition (2)
- laparostomy (2)
- large T antigen (2)
- large vessel occlusion (2)
- laser spectroscopy (2)
- late positive potential (2)
- late-onset (2)
- laterality (2)
- lattices (2)
- law (2)
- learned helplessness (2)
- left ventricular ejection fraction (2)
- left ventricular mass (2)
- left-ventricular function (2)
- length of stay (2)
- lepidoptera (2)
- lessons learned (2)
- life (2)
- life cycle (2)
- life events (2)
- life history strategy (2)
- lifestyle (2)
- ligand (2)
- light pulses (2)
- lineage (2)
- linear regression analysis (2)
- linguistic morphology (2)
- lipid bilayer membrane (2)
- lipid metabolism (2)
- liquid biopsy (2)
- liquid chromatography (2)
- liquid chromatography/mass spectrometry (2)
- liquids (2)
- literature review (2)
- lithium-ion battery (2)
- liver resection (2)
- lncRNAs (2)
- load management (2)
- local adaptation (2)
- local self-governance (2)
- locked-in state (2)
- locked-in syndrome (2)
- locomotor adaptation (2)
- locust outbreak (2)
- logging (2)
- long non-coding RNA (2)
- long-term potentiation (2)
- long-term survivors (2)
- longitudinal studies (2)
- loop quantum gravity (2)
- loss (2)
- low Mach number (2)
- low-grade glioma (2)
- low-valent main group chemistry (2)
- lower body (2)
- lower extremity (2)
- lung-cancer (2)
- lying (2)
- lymph node dissection (2)
- lymphocyte differentiation (2)
- lyso-Gb3 (2)
- lysosomal storage disease (2)
- mRNA expression (2)
- macrocycle (2)
- macrophage polarization (2)
- macular degeneration (2)
- magic (2)
- magnesium (2)
- magnetic anisotropy (2)
- magnetic compass (2)
- magnetic susceptibility (2)
- magnetism (2)
- main group element halides (2)
- main-group chemistry (2)
- maintenance (2)
- maize (2)
- malignant hyperthermia (2)
- malnourishment (2)
- mammalian cells (2)
- mammalian genomics (2)
- manganese (2)
- maps (2)
- marcophages (2)
- marine bacteria (2)
- marine natural product (2)
- markers (2)
- mass casualties (2)
- match load (2)
- materials for optics (2)
- maternal exposure (2)
- mathematical model (2)
- mathematical modeling (2)
- mating success (2)
- matrix protein porin (2)
- meadow (2)
- mean-field theory (2)
- meaning (2)
- measels virus (2)
- measurements (2)
- measures (2)
- mechanisms of disease (2)
- media equation (2)
- mediated apoptosis (2)
- medical (2)
- medical nutrition therapy (2)
- medical students (2)
- medieval manuscripts (2)
- medullary thyroid cancer (2)
- medullary thyroid carcinoma (2)
- medulloblastoma (2)
- megavoltage computed-tomography (2)
- melanoma cells (2)
- melanomas (2)
- melt electrospinning (2)
- membrane biophysics (2)
- membrane protein (2)
- membrane receptor signaling (2)
- membrane skeleton (2)
- membrane trafficking (2)
- membrane vesicles (2)
- men (2)
- men who have sex with men (2)
- mental representation (2)
- mentalizing (2)
- mercapturic acid (2)
- merocyanine (2)
- mesenchymal stem cell (2)
- mesenchymal stromal cell (2)
- mesenchymale Stammzellen (2)
- mesoscopic (2)
- metabolic disease (2)
- metabolic flux (2)
- metabolic flux analysis (2)
- metabolic modelling (2)
- metabolic syndrome (2)
- metabolomic profiling (2)
- metacognitive prompting (2)
- metallic trace elements (2)
- metals (2)
- metamorphic buffer layer (2)
- metaproteomics (2)
- metastasis-directed therapy (2)
- metastatic (2)
- methodological pluralism (2)
- methods (2)
- methylprednisolone (2)
- miR (2)
- miR-182-5p (2)
- miR-30 (2)
- miRNA processing (2)
- microbes (2)
- microbial diversity (2)
- microbial spectrum (2)
- microcephaly (2)
- micronutrients (2)
- microparticles (2)
- microsatellites (2)
- microstructure (2)
- microswimmer (2)
- microtubules (2)
- microvascular complications (2)
- microvasculature (2)
- midazolam (2)
- mild cognitive impairment (2)
- mind–body intervention (2)
- mineral metabolism (2)
- minimal invasive surgery (2)
- minorities (2)
- mismatch (2)
- mitochondrial DNA (2)
- mitotic gene expression (2)
- mixed hearing loss (2)
- mobile apps (2)
- mobile laser scanning (2)
- mobile networks (2)
- moderate (2)
- modified inflation (2)
- modifiers (2)
- modulation spectroscopy (2)
- molecular alterations (2)
- molecular characterization (2)
- molecular cloning (2)
- molecular diagnostics (2)
- molecular epidemiology (2)
- molecular evolution (2)
- molecular mass (2)
- molecular mechanism (2)
- molecular mechanisms (2)
- molecular recognition (2)
- molecular structure (2)
- molecular subtypes (2)
- molecular switch (2)
- monoallelic expression (2)
- mood (2)
- morphogenesis (2)
- morphogenetic protein (2)
- morris water maze (2)
- mosquito (2)
- motivated reasoning (2)
- motor proteins (2)
- mouse-brain (2)
- movement (2)
- movement disorder (2)
- movement interaction (2)
- mtDNA (2)
- mucin (2)
- mucoepidermoid carcinoma (2)
- multi-jet background (2)
- multi-sensor (2)
- multi-wavelength (2)
- multidrug resistance (2)
- multidrug-resistant bacteria (2)
- multigrid (2)
- multimodal (2)
- multiparticle collision dynamics (2)
- multipath (2)
- multipath scheduling (2)
- multiple bonding (2)
- multiple-sclerosis (2)
- multipole refinement (2)
- multivariate analysis (2)
- multivariate data analysis (2)
- muon channel (2)
- muon spectrometer (2)
- murine model (2)
- muscle degeneration (2)
- muscle disease (2)
- musculoskeletal system (2)
- mutagenicity (2)
- mutants (2)
- mutation analysis (2)
- myasthenia gravis (2)
- mycobacterium tuberculosis (2)
- mycotoxins (2)
- myeloid (2)
- myeloma (2)
- myocardial sympathetic innervation imaging (2)
- myocardial work (2)
- myocardial-infarction (2)
- myofibrillar myopathy (2)
- myopathy (2)
- nab-paclitaxel (2)
- naloxone (2)
- nano (2)
- nano rods (2)
- nanographene (2)
- nanolithography (2)
- nanomedicine (2)
- nanophotonics and plasmonics (2)
- nanotechnology (2)
- nanotube (2)
- nanowires (2)
- naphthalene diimide (2)
- narrative text (2)
- natriuretic peptide (2)
- natural killer cells (2)
- natural pest control (2)
- ncRNA (2)
- necrobiome (2)
- necrotic cell death (2)
- nectar (2)
- negative pressure (2)
- neisseria gonorrhoeae (2)
- neoadjuvant (2)
- neocortex (2)
- neonate (2)
- neonates (2)
- neovascularization, physiologic (2)
- nervous-system (2)
- nest building (2)
- nesting habits (2)
- network calculus (2)
- neume notation (2)
- neural circuits (2)
- neural network (2)
- neural stem cell (2)
- neurite outgrowth (2)
- neurodevelopmental disorders (2)
- neuroendocrine tumor (NET) (2)
- neurofascin (2)
- neurofilaments (2)
- neuron (2)
- neuronal dendrites (2)
- neuronal plasticity (2)
- neuroplasticity (2)
- neurosphere (2)
- neurosurgery (2)
- neurotoxicity (2)
- neurotransmission (2)
- neurotransmitter release (2)
- neurotrophic factors (2)
- neutral sphingomyelinase-2 (2)
- neutralino (2)
- neutrino astronomy (2)
- neutrino emission (2)
- neutrino telescope (2)
- neutrinos (2)
- new media (2)
- next generation sequencing (NGS) (2)
- nicht-kartesische Bildgebung (2)
- nicht-kovalente Wechselwirkungen (2)
- nicotine addiction (2)
- nicotinic receptors (2)
- nilotinib (2)
- nitrogen regulation (2)
- nivolumab (2)
- nociception (2)
- nomenclature (2)
- non-Cartesian Imaging (2)
- non-invasive ventilation (2)
- non-penetrating glaucoma surgery (2)
- non-small cell lung cancer (2)
- non-visual (2)
- nonadiabatic dynamics (2)
- noncoding RNA (2)
- noncoding RNAs (2)
- noncovalent interactions (2)
- nonlinear dynamics (2)
- nonlinear optics (2)
- nonlinear spectroscopy (2)
- nonlinear systems (2)
- nonverbal communication (2)
- normal distribution (2)
- nuclear export (2)
- nuclear import (2)
- nuclear magnetic resonance (2)
- nuclear magnetic resonance spectroscopy (2)
- nuclear medicine (2)
- nuclear organization (2)
- nucleic acid (2)
- nucleophilic addition (2)
- nucleosomes (2)
- nucleotide excision-repair (2)
- nucleotide sequence (2)
- nude-mice (2)
- numerical analysis (2)
- numerical hydrodynamics (2)
- nurse bee (2)
- nurses (2)
- o-methoxy-sila-hexocyclium (2)
- object-based classification (2)
- object-based image analysis (2)
- observer (2)
- obstetrics (2)
- occupational medicine/industrial medicine (2)
- oculomotor control (2)
- oestrogen receptor signalling (2)
- office-workers (2)
- oil palm (2)
- older adults (2)
- olfaktorisches Lernen (2)
- oligodendrocyte (2)
- oligomers (2)
- oligorecurrence (2)
- oligothiophenes (2)
- olive (2)
- omega-3 fatty acids (2)
- oncogene-induced senescence (2)
- oncolytic viral therapy (2)
- oncolytic virus therapy (2)
- one-electron oxidation (2)
- online survey (2)
- onset (2)
- open spaces (2)
- opioid peptides (2)
- optic neuritis (2)
- optical (2)
- optical coherence tomography (2)
- optical remote sensing (2)
- optics (2)
- optics and photonics (2)
- optimal control theory (2)
- optimal drug combination (2)
- optogenetic (2)
- oral bioavailability (2)
- oral mucositis (2)
- ordinary culture (2)
- ordinary differential equations (2)
- organ-on-a-chip (2)
- organic electronics (2)
- organic photovoltaic (2)
- organic thin films (2)
- organische Solarzellen (2)
- orthopedic surgery (2)
- osteoclasts (2)
- osteonecrosis of the jaw (2)
- osteopontin (2)
- osteoradionecrosis (2)
- otitis media (2)
- outcomes research (2)
- outer membrane protein (2)
- outer membrane proteins (2)
- outer-membrane proteins (2)
- outpatients (2)
- oxaliplatin (2)
- oxidative addition (2)
- oxygen uptake (2)
- oxytocin (2)
- p-Halbleiter (2)
- p34 (2)
- p44 (2)
- p90 ribosomal S6 kinase (2)
- pCa (2)
- pH (2)
- pICln (2)
- paediatrics (2)
- pain regulation (2)
- pain sensation (2)
- paleogeography (2)
- palladium (2)
- palliative care (2)
- pandemic (2)
- panel sequencing (2)
- parabiosis (2)
- parallel evolution (2)
- parallel imaging (2)
- parasitic cell cycles (2)
- parasitoid (2)
- paraspeckles (2)
- parastomal hernia (2)
- parasympatholytics (2)
- parathyroid hormone (2)
- parietal hypoactivation (2)
- parkinson's disease (2)
- parotid gland (2)
- parthenogenesis (2)
- partial agonists (2)
- partial decay width (2)
- particles (2)
- passive transfer (2)
- pastoral care (2)
- pathogen (2)
- pathogenic bacteria (2)
- pathology (2)
- pathway analysis (2)
- patient education (2)
- patient reported outcome measures (2)
- patient safety (2)
- patient survival (2)
- patient-specific (2)
- pattern (2)
- peak oxygen uptake (2)
- pedagogical content knowledge (2)
- pediatric adrenocortical cancer (2)
- pediatric adrenocortical tumor (2)
- pediatric patients (2)
- peer review (2)
- pelvic examination (2)
- pelvic palpation (2)
- pembrolizumab (2)
- pemphigus foliaceus (2)
- penicillin allergy (2)
- penicillin hypersensitivity (2)
- pentacoordinate (2)
- people (2)
- peptide conjugates (2)
- peptide tyrosine tyrosine (PYY) (2)
- peptide vaccination (2)
- peptides (2)
- performance modeling (2)
- perfusion culture (2)
- pericyclic reaction (2)
- pericytes (2)
- periodization (2)
- perioperative care (2)
- peripartum (2)
- peripheral nerve (2)
- peripheral neuropathy (2)
- periprosthetic joint infection (2)
- peritoneal carcinomatosis (2)
- peroxisomes (2)
- personalised medicine (2)
- personality traits (2)
- personalized treatment (2)
- perspective taking (2)
- perspectives (2)
- perylene bisimides (2)
- perylene dyes (2)
- pest control (2)
- pesticides (2)
- phage (2)
- pharmaceutical analysis (2)
- pharmaceutical applications (2)
- pharmacodynamics (2)
- pharmacokinetic (2)
- pharmacology/toxicology (2)
- pharmacovigilance (2)
- phase transitions and critical phenomena (2)
- phasic affective modulation (2)
- phenprocoumon (2)
- phosphatidylserine (2)
- phosphodiesterase (2)
- phosphoglycolate phosphatase (2)
- phospholipase D (2)
- phosphorus (2)
- photoemission spectroscopy (2)
- photoinduzierter Elektronentransfer (2)
- photolysis (2)
- photon statistics (2)
- photon-counting (2)
- photonic devices (2)
- photoreceptor (2)
- photoreceptors (2)
- photoswitchable organic fluorophores (2)
- photothrombosis (2)
- phototransduction (2)
- physical health (2)
- physical performance (2)
- physical properties (2)
- physiologically based pharmacokinetic (PBPK) modeling (2)
- phytochemicals (2)
- phytochemistry (2)
- phytohormones (2)
- pi-conjugation (2)
- piRNA (2)
- pig (2)
- pigmentation (2)
- piperacillin/tazobactam (2)
- piperidines (2)
- placebo-controlled trial (2)
- planning (2)
- plant (2)
- plant cuticle (2)
- plant defence (2)
- plant defenses (2)
- plant diversity (2)
- plant immunity (2)
- plant quality (2)
- plant–insect interactions (2)
- plaque (2)
- plasma proteins (2)
- plasminogen (2)
- platelet physiology (2)
- platelet receptors (2)
- platyhelminthes (2)
- plausibility (2)
- pleomorphic adenoma (2)
- pneumolysin (2)
- pneumonia (2)
- point of care testing (2)
- pointing gestures (2)
- polarimetry (2)
- polarized epithelium (2)
- policy (2)
- politics of representation (2)
- pollen analysis (2)
- pollen metabarcoding (2)
- pollen tube (2)
- pollination network (2)
- pollinator decline (2)
- pollinator friendly plants (2)
- pollinators (2)
- poly(2- oxazoline) (2)
- polycationic peptides (2)
- polymavirus (2)
- polymer-peptide-conjugate (2)
- polymorphisms (2)
- polymyalgia rheumatica (2)
- polyploidy (2)
- pomalidomide (2)
- population codes (2)
- population-based (2)
- populations (2)
- pore formation (2)
- pose estimation (2)
- positive selection (2)
- positron emission tomography/computed tomography (2)
- post-transcriptional regulation (2)
- posterior parietal cortex (2)
- postmenopausal women (2)
- postnatal development (2)
- postoperative bleeding (2)
- postoperative care (2)
- postoperative nausea and vomiting (2)
- posttranslational modifications (2)
- postural control (2)
- potassium channel (2)
- power training (2)
- pp Collisions (2)
- pp collisions (2)
- pre-messenger RNA (2)
- precision agriculture (2)
- preconditioning (2)
- predation risk (2)
- predictive factors (2)
- predictive marker (2)
- predictive modeling (2)
- predictive performance (2)
- predictive value (2)
- preexisting bias (2)
- prenatal exposure (2)
- prenatal stress (2)
- presynapse (2)
- presynaptic inhibition (2)
- preterm infant (2)
- primary cells (2)
- primary healthcare (2)
- primary prevention (2)
- primary ventral hernia (2)
- primary vertex (2)
- prime number (2)
- priming (2)
- printability (2)
- printed tooth (2)
- probability (2)
- probes (2)
- proboscis extension response (2)
- proboscis extension response (PER) (2)
- process analysis (2)
- prodrug (2)
- productivity (2)
- progenitor cells (2)
- prognostic factors (2)
- programmed cell death (2)
- projection neurons (2)
- promoter methylation (2)
- propensity score matching (2)
- propulsion (2)
- prosociality (2)
- prospective studies (2)
- prostate-cancer (2)
- prostatic neoplasms (2)
- prosthesis (2)
- protease inhibition (2)
- proteasome (2)
- protein adsorption (2)
- protein aggregation (2)
- protein crystallography (2)
- protein hydration (2)
- protein interactions (2)
- protein localization (2)
- protein phosphorylation (2)
- protein-coupled receptors (2)
- protein-interaction networks (2)
- protein-protein interactions (2)
- proteinuria (2)
- proteomes (2)
- proteomic (2)
- proton-proton collisions (2)
- proton-proton-collision (2)
- proton–proton collisions (2)
- psychoeducation (2)
- psycholinguistics (2)
- psychological interventions (2)
- psychological variables (2)
- psychopathology (2)
- psychophysics (2)
- psychosocial stress (2)
- puberty (2)
- public speaking (2)
- pulmonary artery pressure (2)
- pupae (2)
- pyrene dimer (2)
- qPCR (2)
- quality evaluation (2)
- quality of life (QoL) (2)
- quantitative SPECT/CT (2)
- quantitative analysis (2)
- quantity discrimination (2)
- quantum Monte Carlo (2)
- quantum chemistry (2)
- quantum control (2)
- quantum gravity (2)
- quantum point contact (2)
- quantum spin Hall effect (2)
- quantum spin hall insulator (2)
- quantum transport (2)
- quantum well (2)
- quantum wells (2)
- qubit interaction (2)
- qubits (2)
- quinine (2)
- quinoa (2)
- racism (2)
- radiation sensitivity (2)
- radiation-therapy (2)
- radical cystectomy (2)
- radical prostatectomy (2)
- radii (2)
- radio astronomy (2)
- radiofrequency identification (2)
- radiography (2)
- radioiodine (2)
- radiopharmaceuticals (2)
- radiotherapy (RT) (2)
- radiotracer (2)
- raman spectroscopy (2)
- random forest classification (2)
- randomised controlled trial (2)
- randomized trial (2)
- rapid evolution (2)
- rapid prototyping (2)
- rare (2)
- rare diseases (2)
- rat brain membranes (2)
- rat hepatocytes (2)
- rat model (2)
- re-irradiation (2)
- reaction mechanism (2)
- reaction mechanisms (2)
- reactive electrophilic species (2)
- reading comprehension (2)
- reading disability (2)
- real time PCR (2)
- real world evidence (2)
- receptor beta (2)
- receptor signalling (2)
- receptor tyrosine kinase (2)
- reconstructed human epidermis (2)
- recreation (2)
- rectum (2)
- red fluorescent protein (2)
- redox (2)
- redox cascade (2)
- reflection (2)
- reflex (2)
- refugees (2)
- regenerative capacity (2)
- regional climate model (2)
- regional development (2)
- register (2)
- registries (2)
- registry (2)
- regular languages (2)
- regulation of gene expression (2)
- regulatory T cell (2)
- reguläre Sprachen (2)
- regurgitation (2)
- reinforcement learning (2)
- relativistic jets (2)
- relaxation (2)
- relaxation method (2)
- release (2)
- remyelination (2)
- renal cancer (2)
- renal disease (2)
- renal failure (2)
- renal system (2)
- renewable energy (2)
- renewable fuels (2)
- repair and replication (2)
- reperfusion (2)
- reperfusion injury (2)
- replacement therapy (2)
- replica (2)
- replication crisis (2)
- reporter genes (2)
- repositories (2)
- representing matrix (2)
- reproductive success (2)
- reputation (2)
- resonant photoelectron spectroscopy (2)
- resource use (2)
- respiratory chain (2)
- respiratory syncytial virus (2)
- response modalities (2)
- responsiveness (2)
- resting tremor (2)
- restrictive cardiomyopathy (2)
- retention interval (2)
- retina (2)
- retinal development (2)
- retinitis pigmentosa (2)
- retinoblastoma protein (2)
- retinoic acid (2)
- retrieval practice (2)
- retrospective (2)
- retroviral vectors (2)
- reverse shoulder arthroplasty (2)
- reverse transcriptase (2)
- reverse transcriptase-polymerase chain reaction (2)
- reversible posterior leukoencephalopathy syndrome (2)
- revision arthroplasty (2)
- rheology (2)
- ribonucleases (2)
- ribosome profiling (2)
- rice (2)
- ring expansion (2)
- ring-expansion reaction (2)
- risk profiling (2)
- rituximab (2)
- robotic (2)
- robotic surgery (2)
- rodent model (2)
- roentgenographic assessment (2)
- rolipram (2)
- room temperature (2)
- root (2)
- root growth (2)
- roots (2)
- ruthenium bda complexes (2)
- saccharomyces cerevisiae (2)
- safety behavior (2)
- salicylic acid (2)
- salinity stress (2)
- salivary gland (2)
- salivary gland tumors (2)
- sampling method (2)
- sar (2)
- sarcoidosis (2)
- satellite (2)
- satellite communication (2)
- satellite remote sensing (2)
- satisfaction with life (2)
- scaffolds (2)
- scalability (2)
- scanning tunneling spectroscopy (2)
- scapula (2)
- sciatic nerve (2)
- scientific guidelines (2)
- sclerostin (2)
- scoping review (2)
- search (2)
- second hit (2)
- secondary site infection (2)
- secretion systems (2)
- sectoral planning (2)
- sedentary behavior (2)
- see (2)
- selective attention (2)
- selenium (2)
- self-activation (2)
- self-adaptive systems (2)
- self-assembled monolayer (SAM) (2)
- self-aware computing (2)
- self-governance (2)
- self-help (2)
- self-management (2)
- self-regulated learning (2)
- self-renewal (2)
- self-sorting (2)
- semantic coherence (2)
- semantic web (2)
- semi-natural habitat (2)
- semiotics (2)
- semismooth Newton method (2)
- sensitivity analysis (2)
- sensory ecology (2)
- sensory neuropathy (2)
- sensory perception (2)
- sentinel-2 (2)
- septic (2)
- sequence analysis (2)
- serology (2)
- serotonergic system (2)
- serotonin deficiency (2)
- serum concentration (2)
- serum creatinine (2)
- serum resistance (2)
- sevoflurane (2)
- sex chromosome evolution (2)
- sex differentiation (2)
- sex ratio (2)
- sexual conflict (2)
- sexual development (2)
- shape fidelity (2)
- shedding (2)
- short-term memory (2)
- shoulder (2)
- shoulder arthroplasty (2)
- shoulder surgery (2)
- signal cross section (2)
- signal filtering (2)
- signal inhibition (2)
- signaling pathways (2)
- signalling pathways (2)
- signals (2)
- signaltransduction (2)
- signature (2)
- signs and symptoms (2)
- silahexocyclium (2)
- silicon vacancy (2)
- similarity (2)
- simulated signal event (2)
- simultaneous integrated boost (2)
- single electron transistor (2)
- single molecule microscopy (2)
- single photon (2)
- single top event (2)
- single top quark production (2)
- single-cell RNA sequencing (2)
- single-cell RNA-seq (2)
- single-molecule microscopy (2)
- single-nucleotide polymorphisms (2)
- single-sided deafness (2)
- sirolimus (2)
- site-specific RNA cleavage (2)
- situation awareness (2)
- sizing (2)
- skin cancer (2)
- skin model (2)
- skinned fiber (2)
- sleep bruxism (2)
- sleep disorders (2)
- small RNAs (2)
- small nucleolar RNAs (2)
- smart speaker (2)
- smartphone app (2)
- smooth muscle cells (2)
- snoRNA (2)
- snow cover duration (2)
- social (2)
- social capital (2)
- social comparison (2)
- social context (2)
- social decision-making (2)
- social features (2)
- social influence (2)
- social philosophy (2)
- social psychology (2)
- social robot (2)
- social understanding (2)
- sodium channel (2)
- sodium channels (2)
- sofosbuvir (2)
- solar cell (2)
- solid tumors (2)
- solid-state NMR (2)
- solid-state emitters (2)
- solitary bee (2)
- solitary bees (2)
- soluble guanylyl cyclase (2)
- solvent effects (2)
- somatic mosaicism (2)
- somatostatin receptor (SSTR) (2)
- soybean (2)
- spacing effect (2)
- spatial attention (2)
- spatial navigation (2)
- spatial planning (2)
- spatial presence (2)
- spatial scale (2)
- speciation (2)
- species concept (2)
- species diversity (2)
- species-energy-theory (2)
- specific phobia (2)
- speckle tracking (2)
- spectral karyotyping (2)
- speech (2)
- speech perception (2)
- speed (2)
- sperm DNA methylation (2)
- sperm head formation (2)
- spermatocytes (2)
- spermatogenesis (2)
- spermiogenesis (2)
- spheroids (2)
- sphingosine (2)
- sphingosine kinase inhibitor SKI-II (2)
- sphingosine-1-phosphate (2)
- spider (2)
- spin chemistry (2)
- spin polarization (2)
- spin transport (2)
- spinal cord injury (2)
- spinal-cord (2)
- spinal-cord-injury (2)
- spine (2)
- spine radiosurgery (2)
- spin–orbit coupling (2)
- spiral ganglion neuron (2)
- spironolactone (2)
- splice variant (2)
- split-belt treadmill (2)
- spontaneous blinks (2)
- spontaneous symmetry breaking (2)
- sporidia (2)
- squaraine dyes (2)
- ssVEP (2)
- stability analysis (2)
- stage renal-disease (2)
- startle (2)
- state (2)
- state constraints (2)
- stem cell niche (2)
- stem cell therapy (2)
- stent (2)
- stereochemistry (2)
- stereotypes (2)
- stiffness (2)
- stimuli (2)
- strain rate (2)
- strategic management (2)
- stress resilience (2)
- stress resistance (2)
- striatum (2)
- strongly correlated materials (2)
- structural basis (2)
- structural elucidation (2)
- structural synaptic plasticity (2)
- structure analysis (2)
- structure prediction (2)
- structure-activity (2)
- structure-activity relationships (2)
- structure-function relationships (2)
- structured illumination (2)
- structured illumination microscopy (2)
- student training (2)
- study design (2)
- sturgeon (2)
- subcutaneous animal model (2)
- substantia nigra pars compacta (2)
- succession (2)
- suffering (2)
- suicidality (2)
- suicide prevention (2)
- sulfates (2)
- sun exposure (2)
- super-resolution fluorescence microscopy (2)
- superparamagnetism (2)
- supervisors (2)
- support vector machines (2)
- supraglacial lakes (2)
- supramolekulare Chemie (2)
- supraparticles (2)
- surface states (2)
- surgical site infections (2)
- surgical therapy (2)
- surgical treatment (2)
- survival analysis (2)
- survivors (2)
- susceptibility gene (2)
- sustainable agriculture (2)
- sustainable intensification (2)
- sustained inflammation (2)
- swimming (2)
- symptom control (2)
- synapse formation (2)
- synapsin (2)
- synapsis (2)
- synaptische Proteine (2)
- synaptonemal complex (2)
- syndrome (2)
- synergistic effect (2)
- synovial fluid (2)
- synthetic aperture RADAR (2)
- synthetic aperture radar (2)
- synthetic mesh (2)
- systematics (2)
- tactile (2)
- tandem mass spectrometry (2)
- tanzania (2)
- tapeworm (2)
- targeted therapies (2)
- targeting (2)
- targets (2)
- task force (2)
- task switching (2)
- taste (2)
- teacher education (2)
- telecommunication spectral range (2)
- temperate forests (2)
- temporal processing (2)
- temporal-lobe epilepsy (2)
- temporoparietal junction (2)
- tension (2)
- teriparatide (2)
- termites (2)
- terpenes (2)
- terror attack (2)
- testes (2)
- testing effect (2)
- testis (2)
- tetraspanin (2)
- tetromycin (2)
- textile (2)
- the rich (2)
- theory (2)
- theory of mind (2)
- therapeutic antibody (2)
- therapy response (2)
- thermoelectrics (2)
- thermopower (2)
- thermotolerance (2)
- thin films (2)
- thinking (2)
- thorax (2)
- thromboinflammation (2)
- thrombolysis (2)
- thyroid cancer (2)
- time (2)
- time perception (2)
- time-series (2)
- tissue model (2)
- tissue regeneration (2)
- tissue saturation index (2)
- tobacco (2)
- tocilizumab (2)
- tolerability (2)
- toll-like receptors (2)
- tool use (2)
- tooth extraction (2)
- top quark decay (2)
- topic modeling (2)
- topologische Isolatoren (2)
- total joint arthroplasty (2)
- toxicology (2)
- toxin (2)
- trace elements (2)
- tracer (2)
- tracheal cytotoxin (2)
- tracking (2)
- training intensity distribution (2)
- trait emotional intelligence (2)
- trans-Golgi network (2)
- trans-formanilide (2)
- transcription factor MIZ-1 (2)
- transcriptional profiling (2)
- transcriptomic analysis (2)
- transcutaneous vagus nerve stimulation (2)
- transformation (2)
- transformative education (2)
- transforming growth factor-beta 1 (2)
- transient dynamics (2)
- transient middle cerebral artery occlusion (2)
- transiente Absorption (2)
- transiente Absorptionsspektroskopie (2)
- transition (2)
- transition metal complex (2)
- transition metal complexes (2)
- transition metal oxides (2)
- transition metals (2)
- transition radiation (2)
- translation initiation (2)
- translational initiation (2)
- translational regulation (2)
- transnationalism (2)
- transpiration (2)
- transposition (2)
- trap (2)
- trap nests (2)
- trastuzumab (2)
- treatment guidelines (2)
- treatment options (2)
- treatment resistance (2)
- tree cavity (2)
- trees (2)
- trend analysis (2)
- triple in situ hybridization (2)
- triple-negative breast cancer (2)
- triplet (2)
- triquinacene derivatives (2)
- tropical forest (2)
- trust (2)
- trypanosoma brucei (2)
- trypanosomes (2)
- tumor cells (2)
- tumor growth (2)
- tumor immunity (2)
- tumor immunology (2)
- tumor necrosis factor (TNF) (2)
- tumor stem cells (2)
- tumor-infiltrating lymphocytes (2)
- tumorigenesis (2)
- tumour immunology (2)
- turbulence (2)
- two-color microscopy (2)
- two-dimensional topological insulator (2)
- two-photon excited fluorescence (2)
- two-stage exchange (2)
- type 2 diabetes mellitus (2)
- type I interferon (2)
- type VII secretion system (2)
- tyramine (2)
- tyrosine (2)
- tyrosine kinase inhibitor (2)
- tyrosine kinase inhibitors (2)
- tyrosine phosphorylation (2)
- ultrafast spectroscopy (2)
- ultrafiltration (2)
- ultraviolet radiation (2)
- umbilical hernia (2)
- unconventional superconductivity (2)
- unexpressed needs (2)
- unfolded protein response (2)
- universal prevention (2)
- universality (2)
- unmanned aerial vehicles (2)
- unpleasant pictures (2)
- up-regulation (2)
- update (2)
- urban (2)
- uremic toxin (2)
- urine (2)
- urticaria (2)
- usability (2)
- user study (2)
- user-centred design (2)
- user-generated content (2)
- vacancy (2)
- vaccines (2)
- vacuole (2)
- vacuum conditioning (2)
- vacuum-assisted closure (2)
- variant surface glycoprotein (2)
- vascular access (2)
- vascular permeability (2)
- vascular surgery (2)
- vasculature (2)
- vasculogenesis (2)
- vasopressin (2)
- vegetation (2)
- vegetative state (2)
- velocity-dependent collision frequency (2)
- venous system (2)
- ventral hernia (2)
- verdünnt magnetische Halbleiter (2)
- vertebral metastases (2)
- vertebrate (2)
- vertical transmission (2)
- vertigo (2)
- very-long-baseline interferometry (2)
- vesicle trafficking (2)
- vibration (2)
- vicinal surfaces (2)
- video analysis (2)
- virology (2)
- virtual agent (2)
- virtual body ownership (2)
- virtuelle Realität (2)
- virus reactivation (2)
- viscosity (2)
- visible cross section (2)
- visual (2)
- visual attention (2)
- vitamin B6 (2)
- vitamin D deficiency (2)
- vitamins (2)
- vocabulary (2)
- volatile anesthetics (2)
- volatiles (2)
- voltage clamp (2)
- volume regulation (2)
- voluntary movement (2)
- vulnerability (2)
- vulnerability curve (2)
- wR factor = 0.068 (2)
- wasps (2)
- water balance (2)
- water load test (2)
- water microbiology (2)
- water migration (2)
- water purification (2)
- water splitting (2)
- wave functions (2)
- waveguides (2)
- weak statehood (2)
- weakly coordinating anions (2)
- wetland (2)
- white blood cells (2)
- whole exome sequencing (2)
- whole genome sequencing (2)
- whole-exome sequencing (2)
- whole-genome duplication (2)
- wild honey bees (2)
- wind speed (2)
- wood anatomy (2)
- wood-inhabiting fungi (2)
- work capacity evaluation (2)
- work engagement (2)
- worker policing (2)
- workplace (2)
- xenotransplantation (2)
- xylem loading (2)
- yam (2)
- yellow fluorescent protein (2)
- young children (2)
- youth (2)
- zoology (2)
- zwitterionic (2)
- Ökosystem (2)
- Östrogene (2)
- Überlagerung <Mathematik> (2)
- ΔNp63 (2)
- α-synuclein (2)
- γδ T cell (2)
- π-conjugated systems (2)
- "(Ga (1)
- "steepest descent-modest ascent" (1)
- "steilsten Abstieg - schwächste Aufstieg" (1)
- Čerenkov-Zähler (1)
- ( L. ivanovii ) (1)
- ( L. selligeri) (1)
- (+)-limonene (1)
- (0 (1)
- (13)C (1)
- (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium chloride/pharmacology (1)
- (AB)\(_{n}\) segmented copolymers (1)
- (Bio-)Stratigraphie (1)
- (Ga (1)
- (Ga,Mn)As (1)
- (Mouse L-cell) (1)
- (Nucleotide sequence (1)
- (R)- and (S)-hexahydro- / Antimuscarinic properties / Muscarinic receptor subtypes (1)
- (Rat brain membrane) (1)
- (Rat liver) (1)
- (S (1)
- (Salmonella) (1)
- (Signal transduction pathways) (1)
- (approximate) functional equation (1)
- (bi)pyridine-based ligand (1)
- (bio-)stratigraphy (1)
- (cardiac) surgery (1)
- (classical and atypical) Werner syndrome (1)
- (dis-)embeddedness (1)
- (hem)ITAM signaling (1)
- (resonant) photoemission spectroscopy (1)
- (± )-dioncophyllacine A (1)
- *-algebra (1)
- + (1)
- - (1)
- . (1)
- .................................................................... (1)
- 0 antigen (1)
- 1)-Matrix (1)
- 1)-matrix (1)
- 1,2-additionreaction (1)
- 1,2-additions (1)
- 1,2-azaborinine (1)
- 1,2-benzisothiazolinone (1)
- 1,25-dihydroxyvitamin D\(_{3}\) (1)
- 1,4-Diborabenzene (1)
- 1,4-naphthoquinone (1)
- 1/N expansion (1)
- 11C-Hydroxyephedrine (1)
- 11C-Methionine PET/CT (1)
- 11C-hydroxyephedrine (1)
- 12-oxo-phytodienoic acid (1)
- 123I-Ioflupane (1)
- 131I (1)
- 133Ba (1)
- 14 (1)
- 14-3-3s (1)
- 14.7K (1)
- 1458-1463 (1)
- 15-Deoxyspergualin (1)
- 1550 nm (1)
- 1655-1705> (1)
- 16S metabarcoding (1)
- 16S ribosomal-RNA (1)
- 177Lu SPECT/CT imaging (1)
- 177Lu-DOTATATE (1)
- 177Lu-DOTATOC (1)
- 177Lu-OPS201 (1)
- 17beta-Estradiol (1)
- 17beta-estradiol (1)
- 17ßEstradiol (1)
- 18-F-fluorothymidine uptake (1)
- 18F-DCFPL (1)
- 18F-flurpiridaz (1)
- 18FDG-PET/CT (1)
- 18FFBnTP (1)
- 18S (1)
- 18S rRNA (1)
- 19. Jahrhundert (1)
- 1960s (1)
- 1994> (1)
- 19F-MR (1)
- 19F-NMR (1)
- 1D transport (1)
- 1ES 1011+496 (1)
- 1ES 2344+514 (1)
- 1ES1218+304 (1)
- 1H-Magnetic resonance spectroscopy (1H-MRS) (1)
- 1H-NMR-Spectroscopy (1)
- 1p13.3 (1)
- 1p36 deletion syndrome (1)
- 1q21 (1)
- 1st International Workshop (1)
- 1st-line treatment (1)
- 2 (1)
- 2 Jets (1)
- 2 PM (1)
- 2"-> (1)
- 2',7'-dichlorofluorescin (1)
- 2':6' (1)
- 2,5-diketopiperazines (1)
- 2- deoxy-2-(18F)fluoro-D-glucose (1)
- 2-Acetylaminofluorene (1)
- 2-Aminoethylphosphonic acid (1)
- 2-DG (1)
- 2-Dichloroethane (1)
- 2-Dioxetane (1)
- 2-Generation reproduction (1)
- 2-Thiazaphospholidines (1)
- 2-a:6 (1)
- 2-acetylaminofluorene (1)
- 2-alkylbranched acids (1)
- 2-chloro (1)
- 2-component system (1)
- 2-deoxy-2-(18F)fluoro-D-glucose (1)
- 2-deoxy-2-18F-fluoro-D-sorbitol (1)
- 2-deoxy-D-glucose (1)
- 2-dimensional speckle tracking (1)
- 2-halo (1)
- 2-imino- (1)
- 2-loop level (1)
- 2-photon absorption (1)
- 2-photon microscopy (1)
- 2-point Dixon (1)
- 2-pore potassium channel (1)
- 2-step IMRT (1)
- 21q22.2-q22.3 (1)
- 223Ra (1)
- 224Ra (1)
- 22q11.2 deletion syndrome (1)
- 25-hydroxycholesterol 7 alpha-hydroxylase (1)
- 26S RDNA Data (1)
- 26S proteasome (1)
- 28 (1)
- 28-22 (1)
- 29Si-NMR (1)
- 2D (1)
- 2D material (1)
- 2D-perfusion angiography (1)
- 2PI Formalism (1)
- 2n+3 (1)
- 2ϕ\(_0\) periodicity (1)
- 3 D bioprinting (1)
- 3 D rotational fluoroscopy (1)
- 3 Tesla (1)
- 3 dimensional cell culture model (1)
- 3-D liver model (1)
- 3-coordinate boron (1)
- 3-coordinate organoboron compounds (1)
- 3-dimensional MRI (1)
- 3-dimensional structure (1)
- 3-dimensional visualization (1)
- 3-pentafluoropropene (1)
- 3-tetrafluoropropene (1)
- 316L stainless-steel (1)
- 360° videos (1)
- 3C 279 (1)
- 3D Bioprinting (1)
- 3D GIS analysis (1)
- 3D Gewebemodelle (1)
- 3D Ko-kulture (1)
- 3D Laser Scanning (1)
- 3D Modell (1)
- 3D Point Cloud Processing (1)
- 3D Pointcloud (1)
- 3D Punktwolke (1)
- 3D Reconstruction (1)
- 3D Sensor (1)
- 3D Tumormodell (1)
- 3D Vision (1)
- 3D X-ray microscopy (1)
- 3D analysis (1)
- 3D breast cancer model (1)
- 3D cell cultures (1)
- 3D collation (1)
- 3D conformal silicone bolus (1)
- 3D culture (1)
- 3D cultures (1)
- 3D echocardiography (1)
- 3D electrophysiology (1)
- 3D ex vivo models (1)
- 3D image analysis (1)
- 3D in vitro model (1)
- 3D in vitro models (1)
- 3D lung tumor tissue models (1)
- 3D mapping (1)
- 3D microfiber (1)
- 3D microscopy (1)
- 3D model (1)
- 3D model systems (1)
- 3D modeling (1)
- 3D muscle (1)
- 3D neuronal networks (1)
- 3D object recognition (1)
- 3D organoids (1)
- 3D point cloud (1)
- 3D printer (1)
- 3D remote sensing (1)
- 3D spheroid culture (1)
- 3D structure (1)
- 3D thermal mapping (1)
- 3D tissue models (1)
- 3D topological insulator (1)
- 3D tumor model (1)
- 3D viewer (1)
- 3D-ERT electrical resistivity tomography (1)
- 3D-Gewebemodell (1)
- 3D-Modell (1)
- 3D-Rekonstruktion (1)
- 3D-Struktur (1)
- 3D-conformal radiotherapy (1)
- 3D-druck (1)
- 3D-printed tooth (1)
- 3D-reconstruction methods (1)
- 3DTK toolkit (1)
- 3R (1)
- 3d point clouds (1)
- 3 T (1)
- 3‐D electrical resistivity imaging (1)
- 3′ UTR (1)
- 4'-hydroxylation (1)
- 4-(p-nitrobenzyl)pyridine (1)
- 4-HNE (1)
- 4-dimethylamino-4′-cyanodiphenylacetylene (1)
- 4D (1)
- 4D flow MRI (1)
- 4D flow cardiovascular magnetic resonance (1)
- 4D-GIS (1)
- 4D-MRI (1)
- 4G Networks (1)
- 4H (1)
- 4TH-Corner Problem (1)
- 5'-O-Methyldioncophylline D (1)
- 5-HT (1)
- 5-HT receptors (1)
- 5-HTT (1)
- 5-HTT knockout mice (1)
- 5-HTTLPR polymorphism (1)
- 5-a']diindol (1)
- 5-a']diindole (1)
- 5-b']diindol (1)
- 5-b']diindole (1)
- 5-bromodeoxyuridine (1)
- 5-methyl cytosine (1)
- 5-methylcytosine (1)
- 5G core network (1)
- 5G-ATSSS (1)
- 5GC (1)
- 5HTTLPR (1)
- 5IA-SPECT (1)
- 5]diazocino[1 (1)
- 5`-UTR (1)
- 6-benzylaminopurine (1)
- 6-percent hydroxyethyl starch (1)
- 60-nucleotide duplication (1)
- 65-kda isoform (1)
- 68Ga-DOTANOC (1)
- 68Ga-DOTATATE/-TOC (1)
- 68Ga-DOTATOC (1)
- 68Ga-OPS202 (1)
- 68Ga-PSMA ligand PET/CT (1)
- 68Ga-Pentixafor PET/CT (1)
- 6DOF Pose Estimation (1)
- 6G (1)
- 6S RNA (1)
- 7,8-dihydroxyflavone (7,8-DHF) (1)
- 7-Dehydrocholesterol (1)
- 7000 GeV-cms (1)
- 77-LH-28-1 (1)
- 7SK (1)
- 7q11.2 (1)
- 8 TEV (1)
- 8-Hydroxy-deoxyguanosine (1)
- 8-oxoguanine (1)
- 9-borafluorene (1)
- 99mTc-DTPA (1)
- <sup>18</sup>F-FDG (1)
- <sup>68</sup>Ga-Pentixafor (1)
- A chromosomes (1)
- A(2B) receptors (1)
- A-D (1)
- A-D-A dyes (1)
- A-RAF (1)
- A-delta fibers (1)
- A-type lamins (1)
- A. abbreviatus (1)
- A. fumigatus (1)
- A. likoko (1)
- A. thaliana (1)
- A1 (1)
- A1 Adenosine receptors (1)
- A20 (1)
- A2B adenosine receptor (1)
- A2BAR (1)
- A2a-R receptor (1)
- A375 (1)
- A53T (1)
- A549 cell line (1)
- A<sub>2</sub> Adenosine receptor (1)
- AAA+ ATPase p97 (1)
- AAC (1)
- AAER (1)
- AAPA (1)
- AAV vector (1)
- ABA receptors (1)
- ABL gene (1)
- ABP1 (1)
- AC Stark effect (1)
- ACC deaminase (1)
- ACC/AHA classification (1)
- ACE inhibitor (1)
- ACH-2 (1)
- ACID (1)
- ACKR4 (1)
- ACM (1)
- ACP5 (1)
- ACPC (1)
- ACR practice guidelines (1)
- AChE inhibitor (1)
- AD mouse modele (1)
- AD pathogenesis (1)
- AD-AID (1)
- AD5 mutation (1)
- ADAM10 (1)
- ADAM9 (1)
- ADAMTS (1)
- ADCC (1)
- ADGRL3 (1)
- ADHD patients (1)
- ADME analysis (1)
- ADMM (1)
- ADP-ribosylation toxins (1)
- ADP-ribosyltransferases (1)
- ADSC (1)
- ADSCs (1)
- AF-DX 116 (1)
- AFLP (1)
- AG(110) (1)
- AGP (1)
- AGT (1)
- AHRR (1)
- AICDA (1)
- AID-ΔE4a (1)
- AIE (1)
- AIM (1)
- AIME (1)
- AIModules (1)
- AIRWAYS ICPs (1)
- AKI (1)
- AKR-2B (1)
- AKT-signaling (1)
- ALAN (1)
- ALBA Proteine (1)
- ALBA proteins (1)
- ALI culture (1)
- ALK-1 (1)
- ALOS (1)
- ALOS-2 (1)
- ALPH (1)
- ALPH1 (1)
- ALPL (1)
- ALS mimic (1)
- ALS treatment (1)
- ALSIN gene (1)
- ALT (1)
- ALiOS (1)
- AMP (1)
- AMP-activated kinases (1)
- AMP-activated protein kinase (AMPK) (1)
- AMP‐activated protein kinase (1)
- AMR (1)
- ANTARES telescope (1)
- AOM/DSS (1)
- AP-1 (1)
- APC (1)
- APEC (1)
- APERIO (1)
- APERIO Hybrid (1)
- APEX2 (1)
- API (1)
- API-Massenspektrometrie (1)
- APRI (1)
- AQP4 (1)
- ARCI (1)
- ARCI EM type III (1)
- ARDS (acute respiratory distress syndrome) (1)
- ARF (1)
- ARF tumor-suppressor induced lymphomagenes (1)
- ARF6 GTPase (1)
- ARHI (1)
- ARIMA (1)
- ART outcome (1)
- ARVC (1)
- AS clavicle plate (1)
- ASAR (1)
- ASAXS (1)
- ASCAT (1)
- ASCs (1)
- ASE formula (1)
- ASSET4 (1)
- AT/RT (1)
- ATF6 (1)
- ATG (1)
- ATG proteins (1)
- ATG12-ATG5 conjugate (1)
- ATG7 (1)
- ATG8 (1)
- ATGL (1)
- ATLAS New Small Wheel (1)
- ATLAS New Small Wheels (NSW) (1)
- ATLAS experiment (1)
- ATLAS-Detektor (1)
- ATM (1)
- ATM gene (1)
- ATMP (1)
- ATP carrier (1)
- ATP generation (1)
- ATP synthase (1)
- ATP-DnaA complex (1)
- ATP-adenosine triphosphate (1)
- ATP-binding cassette transporter (1)
- ATPase activity (1)
- ATPase mutants (1)
- ATR-FTIR (1)
- ATRA (1)
- ATRX (1)
- ATSSSS (1)
- ATTRv amyloidosis (1)
- AUM (1)
- AUX1 (1)
- AVA (1)
- AVHRR data (1)
- AYAs (1)
- AZD4547 (1)
- AZD6244 (1)
- A\(_{2A}\) adenosine receptor antagonist (1)
- Aaskäfer (1)
- Ab Interno Trabekulektomie (1)
- Ab interno trabeculectomy (1)
- Abatacept (1)
- Abbildungseigenschaften (1)
- Abelsche Gruppe (1)
- Abelson helper integration-1 (AHI1) (1)
- Aberration (1)
- Abfallbehandlung (1)
- Abfallwirtschaft (1)
- Abhängigkeitsmaß (1)
- Abhängigskeitsgraph (1)
- Abl (1)
- Ablation <Medizin> (1)
- Ableitung (1)
- Abreicherung (1)
- Abschattung (1)
- Abschlussprüferhonorar (1)
- Abscisic Acid (1)
- Absolute Configuration (1)
- Absolute Konfiguration (1)
- Absorbed Doses (1)
- Absorption (1)
- Absorptionsspektroskopie (1)
- Abstandsmessung (1)
- Abstiegsverfahren (1)
- Abstimmbarer Laser (1)
- Abstoßungsphänomen (1)
- Abszision (1)
- Abundance (1)
- Abwehrmechanismen (1)
- Abwärmenutzung (1)
- Academic Professionalisation (1)
- Academic Skills (1)
- Accelerated imaging (1)
- Accelerator modelling and simulations (multi-particle dynamics; single-particle dynamics) (1)
- Accelerometry (1)
- Accessibility (1)
- Accidental coincidence (1)
- Accountability (1)
- Accounting (1)
- Accounts (1)
- Accumulative Femtosecond Spectroscopy (1)
- Accurate (1)
- Accurate crop monitoring (1)
- Acene (1)
- Acenes (1)
- Acer platanoides (1)
- Acetabularia (1)
- Acetaminophen (1)
- Acetylated tubulin (1)
- Acetylcholinrezeptor (1)
- Acetylcysteinderivate (1)
- Acetylierung (1)
- Acetylneuraminsäure <N-> (1)
- Achillea Fragrantissima (1)
- Achilles tendinopathy (1)
- Acid Sphingomyelinase (1)
- Acid adaptation (1)
- Acids (1)
- Acipenser baerii (1)
- Ackerrandstreifen (1)
- Acoustic equations (1)
- Acoustic neuroma (1)
- Acoustics (1)
- Acquisition of literacy (1)
- AcrAB-TolC efflux pump (1)
- Acromesomelic dysplasias (1)
- Acromyrmex (1)
- Acromyrmex ambiguus (1)
- Acromyrmex heyeri (1)
- Acrylamid (1)
- Acrylamide (1)
- Actin Dynamics (1)
- Actin binding proteins (1)
- Actin cytoskeleton (1)
- Actin cytoskeleton-related protein (1)
- Actin-Polymerisation (1)
- Actinoide (1)
- Actinokineospora (1)
- Actinomyces (1)
- Actinomycin D (1)
- Action feedback (1)
- Action potentials (1)
- Activation induced cell death/AICD (1)
- Active Galaxies (1)
- Active disease (1)
- Active galactic nuclei (1)
- Active pharmaceutical ingredients (1)
- Active self (1)
- Active zone (1)
- Activist Scholarship (1)
- Acute Myocardial Infarction (1)
- Acute lymphoblastic leukemia (1)
- Acute osteomyelitis (1)
- Acute tryptophan depletion (1)
- Ad Philocratem (1)
- AdMSC (1)
- AdS-CFT correspondence (1)
- Adamantiades-Behçet disease (1)
- Adapter-Protein (1)
- Adapterprotein (1)
- Adaptive Governance (1)
- Adaptive Optimierung (1)
- Adaptive Video Streaming (1)
- Adaptive cell transfer (1)
- Adaptives Immunsystem (1)
- Adaptives System (1)
- Adaptives Videostreaming (1)
- Add-on-Miss (1)
- Addiction (1)
- Addison's disease (1)
- Addisons disease (1)
- Additive Fertigung (1)
- Addukt (1)
- Adenocarcinomas (1)
- Adenosine receptor (1)
- Adenosine receptor antagonists (1)
- Adenovirus (1)
- Adenylate cyclase toxin (1)
- Adherence (1)
- Adherens junction (1)
- Adhesion (1)
- Adhesion and Invasion (1)
- Adhesion and degranulation promoting adapter protein (1)
- Adhesive Hydrogels (1)
- Adhäsine (1)
- Adiabatic Perturbation Theory (1)
- Adiabatic Theorem of quantum mechanics (1)
- Adipokine (1)
- Adipose (1)
- Adipose Tissue (1)
- Adipose Tissue Engineering (1)
- Adipose-Derived Stromal/Stem Cells (1)
- Adipozyten (1)
- Administered Activities (1)
- Admission Control (1)
- Adolescence (1)
- Adolescent (1)
- Adolescents (1)
- Adolf Hurwitz (1)
- Adrenalin (1)
- Adrenergic receptor (1)
- Adrenocortial carcinomas (1)
- Adrenokortikales Karzinom (1)
- Adsorbat (1)
- Adsorptionskinetik (1)
- Adsorptionsschicht (1)
- Adult Education (1)
- Adult head (1)
- Adult patients (1)
- Adults (1)
- Adultschlupfes (1)
- Advanced Driver Assistance Systems (1)
- Advanced snowmelt (1)
- Adventitia (1)
- Adverse outcome pathway (AOP) (1)
- Advertising (1)
- Aeolian Islands (1)
- Aeolische Inseln (1)
- Aerosol (1)
- Aescin (1)
- Affect regulation (1)
- Affective Startle Modulation (1)
- Affective processing (1)
- Affektive Schreckreflexmodulation (1)
- Afferent nerve stimulation (1)
- Affine Skalierungsverfahren (1)
- Affinity probe (1)
- Afghanistan (1)
- Aflatoxin (1)
- Aflatoxin B1 (1)
- Africa south of the equator (1)
- African Traditional Religion (1)
- African Trypanosomiasis (1)
- African agriculture (1)
- African sleeping sickness (1)
- African trypanosome (1)
- African-americans (1)
- Afrikanische Traditionellle Religion (1)
- Afro- Neotropen (1)
- Afro- Neotropics (1)
- Ag-DNA (1)
- Agalsidase beta therapy (1)
- Agarose (1)
- Age (1)
- Age-related macular degeneration (1)
- Ageing (1)
- Agency-Theorie (1)
- Agent <Künstliche Intelligenz> (1)
- Agenten-basierte Computersimulation (1)
- Agentenbasierte Modellierung (1)
- Aggeneys (1)
- Aggregate (1)
- Aggressive Driving (1)
- Aggressive behaviour (1)
- Agoraphobia (1)
- Agoraphobie (1)
- Agrarlandschaft (1)
- Agrarproduktion (1)
- Agrarumweltmaßnahmen (1)
- Agricultural intensification (1)
- Agricultural land use (1)
- Agricultural soil science (1)
- Agriculture (1)
- Agriculture intensification (1)
- Agro-ecology (1)
- Agrobacterium (1)
- Aharonov-Bohm (1)
- Aharonov-Bohm effect (1)
- Aharonov-Bohm-Effekt (1)
- Aharonov-Casher phase (1)
- Aharonov-Casher-Effekt (1)
- Ahmed (1)
- Air pollution (1)
- Airborne particles (1)
- Airway epithelia (1)
- Ajlun <Region> (1)
- Akaba (1)
- Ako na Uche (1)
- Akt/PKB (1)
- Aktienmarkt (1)
- Aktin (1)
- Aktin Zytoskelett (1)
- Aktinnukleation (1)
- Aktionsforschung (1)
- Aktionärsabstimmungen (1)
- Aktive Galaxie (1)
- Aktive Zone (1)
- Aktivierung (1)
- Aktivierungsenergie (1)
- Aktivist (1)
- Aktivsubstanzen (1)
- Akupunktur (1)
- Akutes Nierenversagen (1)
- Akzeptanz (1)
- Akzeptanz- und Commitment Therapie (1)
- Akzeptor <Chemie> (1)
- Akzeptorgruppe (1)
- Akzessibilität (1)
- Albendazol (1)
- Albino rat (1)
- Albrecht Achilles (1)
- Alcohol dependence (1)
- Aldehyde Bioconjugation (1)
- Aldehyde Complexes (1)
- AldoA (1)
- Aldosteronantagonist (1)
- Alemtuzumab (1)
- Alento hydrological observatory (1)
- Algebraic Curves (1)
- Algebraic signal processing (1)
- Algebraische Kurve (1)
- Algebraische Quantenfeldtheorie (1)
- Algebraische Signalverarbeitung (1)
- Algebraische Zahlentheorie (1)
- Algebraischer Funktionenkörper (1)
- Algen (1)
- Algorithmik (1)
- Alien limb syndrome (1)
- Aliphatics (1)
- Alkaline phosphatase (1)
- Alkamiden (1)
- Alkamides (1)
- Alkekengi (1)
- Alkine (1)
- Alkoxylradikale (1)
- Alkoxylradikals (1)
- Alkyl(amino)carbene (1)
- Alkylation (1)
- Alkylpyrazine (1)
- Alkyltransferase Ribozyme SAMURI (1)
- Alkyne (1)
- Allelic loss (1)
- Allergic rhinitis (1)
- Allgemeine Psychologie (1)
- Allgemeine Relativitätstheorie (1)
- Allgemeine Zelle (1)
- Alliances (1)
- Alloantigen (1)
- Alloantigen Expression (1)
- Allocation Planning (1)
- Allogene Zelle (1)
- Allogeneic transplantation (1)
- Allogenic hematopoietic stem cell transplantation (1)
- Allopeptidb (1)
- Allophrynidae (1)
- Allorhizobium vitis (1)
- Allosteric Modulator (1)
- Allosterie (1)
- Allosterisch Modurator (1)
- Allosterischer Effektor (1)
- Allotransplantatabstossung (1)
- Allotransplantation (1)
- Alpaca (1)
- Alpelisib (1)
- Alpha (1)
- Alpha Neurofeedback (1)
- Alpha galactosidase (1)
- Alpha power (1)
- Alpha therapy (1)
- Alpha-Aktivität (1)
- Alpha-Galactosidase (1)
- Alpha-dependent apoptosis (1)
- Alpha-galactosidase (1)
- Alpha-synuclein oligomers (1)
- Alphabetisierung (1)
- Alpine habitats (1)
- Altenpflege (1)
- Alter (1)
- Alter Druck (1)
- Alternaria (1)
- Alternative Conflict Resolutions (1)
- Alternative polyadenylation (1)
- Alternative test methods (1)
- Altersunterschied (1)
- Altertum (1)
- Alterung (1)
- Altproterozoikum (1)
- Aluminium (1)
- Aluminium-copper (1)
- Aluminiumhydridderivate (1)
- Alveolar Echinococcosis (1)
- Alveoläre Echinokokkose (1)
- Alvis (1)
- Alzheimer (1)
- Alzheimer Dementia (1)
- Alzheimer Erkrankung (1)
- Alzheimer's Dementia (1)
- Alzheimer's diseas (1)
- Alzheimer`s disease (1)
- Alzheimers-disease (1)
- Alzheimer’s dementia (1)
- Alzheimer′s disease (1)
- AmGr1 (1)
- AmGr1, AmGr2, AmGr3 (1)
- AmGr2 (1)
- AmGr3 (1)
- Amantadine (1)
- Amazon Molly (1)
- Amazonia (1)
- Amazonian forest (1)
- Ambipolarer Ladungstransport (1)
- Ambrosia beetles (1)
- Ambrosiakäfer (1)
- Ambulantes Assessment (1)
- Ambulatory Assessment (1)
- Amduat (1)
- Ameisengäste (1)
- Ameisenoogenese (1)
- American Studies (1)
- American Thyroid Association (1)
- American foulbrood (1)
- Amerikanisches Englisch (1)
- Amerikanistik (1)
- Amine (1)
- Aminerge Nervenzelle (1)
- Amino Acids (1)
- Amino acid composition (1)
- Aminobisphosphonat (1)
- Aminobisphosphonate (1)
- Aminobuttersäure <gamma-> (1)
- Aminosäure (1)
- Ammoniumpermease (1)
- Ampfer (1)
- Amphibia (1)
- Amphibians (1)
- Amphibien (1)
- Amphibiengemeinschaften (1)
- Amphibolit (1)
- Amphiphile Verbindungen (1)
- Amplicon Sequencing (1)
- Amplitude (1)
- Amu Darya (1)
- Amyloid <beta-> (1)
- Amyloid-beta oligomers; (1)
- Amyotrophe Lateralsklerose (1)
- Amyotrophic Lateral Sclerosis (1)
- Amyotrophic Lateral Sclerosis (ALS) (1)
- Amyotrophic Lateral Sclerosis Assessment Questionnaire 5 (ALSAQ-5) (1)
- Amyotrophic lateral sclerosis (1)
- Amyotrophic-lateral-sclerosis (1)
- Anabolieagent (1)
- Anacardic acid derivatives (1)
- Anacardsäurederivate (1)
- Analgesia (1)
- Analgesie (1)
- Analogschaltung (1)
- Analysis of RNA Modifications (1)
- Analysis of Variance (1)
- Analytical Quality by Design (1)
- Analytik (1)
- Analytische Zahlentheorie (1)
- Anaphylactic shock (1)
- Anaphylatoxine (1)
- Anaphylatoxinrezeptoren (1)
- Anarchic limb syndrome (1)
- Anas crecca (1)
- Anatomic reattachment (1)
- Anatomie (1)
- Anchimeric assistance in solvolysis (1)
- Ancistrocladus ealaensis (1)
- Ancistrocladus likoko (1)
- Ancistrolikokine E3 (1)
- Andalusian varieties (1)
- Anden (1)
- Anderson impurity model (1)
- Anderson-Fabry Disease (1)
- Anderson-Lokalisation (1)
- Androgenetic (1)
- Androgenetisch (1)
- Androstadienon (1)
- Anergy (1)
- Aneuploidie (1)
- Anger (1)
- Angewandte Geowissenschaften (1)
- Angewandte Linguistik (1)
- Angewandte Mathematik (1)
- Angewandte Mikrobiologie (1)
- Angiopoietin-2 (1)
- Angiopoietin-like 4 (1)
- Angiosperms ; Ant-plant interactions ; domatia ; Flora of Malaysia (1)
- Angiotensin-II-Blocker (1)
- Angle-resolved Photoemission Spectroscopy (1)
- Angola (1)
- Angst als Eigenschaft (1)
- Angst als Zustand (1)
- Angsterkrankung (1)
- Angstverarbeitung (1)
- Angular Density (1)
- Aniline derivatives (1)
- Animal Spirits (1)
- Animal Tracking (1)
- Animal behavior (1)
- Animal behavior IntelliCage system (1)
- Animal studies (1)
- Animales Nervensystem (1)
- Anion channel (1)
- Anionenkanal (1)
- Anisotropes Universum (1)
- Anisotropic Magnetoresistance (1)
- Anisotropic Universe (1)
- Anisotropic structures (1)
- Anisotropy (1)
- Ankerfibrillen (1)
- Ankerland (1)
- Ankyrin (1)
- Annaeherung (1)
- Annapurna Conservation Area (1)
- Annäherung-Vermeidung (1)
- Anoikis (1)
- Anomalie (1)
- Anomalieerkennung (1)
- Anomalous magnetic-moment (1)
- Anopheles stephensi (1)
- Anorganische Polymere (1)
- Anorthosit (1)
- Anoxie (1)
- Anpassungstest (1)
- Anrege-Abfrage-Spektroskopie (1)
- Anreize (1)
- Anreizsystem (1)
- Ant (1)
- Ant-following birds (1)
- Ant-plant interactions (1)
- Ant-plant interactions ; Herbivory Macaranga ; Mutualism ; Myrmecophytes (1)
- Ant/plant interaction (1)
- Antagonismus (1)
- Antagonist (1)
- Antarktis (1)
- Anterior chamber perfusion model (1)
- Anterior inferotemporal cortex (1)
- Anthracen (1)
- Anthraquinone glycosides (1)
- Anthrax Toxin (1)
- Anthrax toxin (1)
- Anthropogen (1)
- Anti-TNF-alpha agents (1)
- Anti-infectious activity (1)
- Anti-infective (1)
- Anti-tank rocket (1)
- Anti-tank weapon (1)
- Antiausterity activity (1)
- Antibacterial therapy (1)
- Antibacterials (1)
- Antibiotic (1)
- Antibiotic resistance (1)
- Antibiotics (1)
- Antibiotika (1)
- Antibody clearance (1)
- Antibody index (1)
- Antibody responses (1)
- Anticipation (1)
- Anticoagulants (1)
- Antidepressants (1)
- Antiferromagnet (1)
- Antiferromagnetikum (1)
- Antigen 4 (1)
- Antigen CD19 (1)
- Antigen CD23 (1)
- Antigen CD40 (1)
- Antigen CD44 (1)
- Antigen presentation (1)
- Antigen recognition (1)
- Antigenrezeptor (1)
- Antiinfektiva (1)
- Antikörperantworten (1)
- Antimalariamittel (1)
- Antimicrobial activities (1)
- Antimicrobial activity (1)
- Antimicrobial proteins (1)
- Antimikrobielle Aktivitäten (1)
- Antimikrobielle Peptide (1)
- Antimon (1)
- Antimonide (1)
- Antioxidans (1)
- Antioxidants (1)
- Antiparanodal Autoantibodies (1)
- Antisocial behavior (1)
- Antithrombotics (1)
- Antithrombotika (1)
- Antithrombotikum (1)
- Antitrypanosomal (1)
- Antitrypanosomen (1)
- Antitumor (1)
- Antitumor-Antibiotikum (1)
- Antitumor-antibitioc (1)
- Antiviral nucleoside analogues (1)
- Antonym (1)
- Antworthemmung (1)
- Antwortschwellen (1)
- Antwortverhalten (1)
- Anubispavian (1)
- Anwendungsfall (1)
- Anxiety Disorders (1)
- Anxiety disorders (1)
- Anxiety sensitivity (1)
- Anxiety-like behavior (1)
- Anxiolysis (1)
- Any Evil (1)
- Anämie (1)
- Anästhesiologie (1)
- Aortenaneurysma (1)
- Aortic arch (1)
- ApaH (1)
- ApaH like phosphatase (1)
- Apallisches Syndrom (1)
- Aphthae (1)
- Apicomplexan (1)
- Apidae (1)
- Apis dorsata (1)
- Apis mellifera carnica (1)
- Aplastic anemia (1)
- Aplysina aerophoba (1)
- ApoE\(^{(-/-)}\) (1)
- Apologetic (1)
- Apologetik (1)
- Apple Watch 7 (1)
- Application-Aware Resource Management (1)
- Applied physics (1)
- Approach-Avoidance (1)
- Approved immunomodulators (1)
- Aquaculture (1)
- Aquakultur (1)
- Aquaporin-4 antibodies (AQP4-Ig, NMO-IgG)G (1)
- Aquaporin-4 antibodies (AQP4-IgG) (1)
- Aquaporin-4 antibodies (AQP4-IgG, NMO-IgG) (1)
- Aquaporine (1)
- Aqueous Solution Photochemistry (1)
- Aquinas (1)
- Arabidopsis-thaliana (1)
- Arachidonsäure (1)
- Aragonien (1)
- Araneidae (1)
- Araneus diadematus (1)
- Arbeit (1)
- Arbeiterinnen Fortpflanzung (1)
- Arbeitsketten (1)
- Arbeitsmarkttheorie (1)
- Arbeitsmobilität (1)
- Arbeitsplatzsicherung (1)
- Arbeitsschutz (1)
- Arbeitssicherheit (1)
- Arbitrary Lagrangian-Eulerian (1)
- ArcCHECK (1)
- Archaebakterien (1)
- Archaeology (1)
- Archaikum <Geologie> (1)
- Archean (1)
- Archimedean copula (1)
- Archäometrie (1)
- Areal (1)
- Arena experiment (1)
- Arene-Fluoroarene (1)
- Argentina (1)
- Argonaute (1)
- Argumentation (1)
- Arid biomes (1)
- Aristeas 〈Epistolographus, ca. v3. Jh.〉 (1)
- Aristeas, Epistolographus : Ad Philocratem (1)
- Aromaten (1)
- Aromatic Systems (1)
- Aromatic-hydrocarbon (1)
- Arp2/3 complex (1)
- Arrestine (1)
- Arrhenius equation (1)
- ArsZ (1)
- Artefakt (1)
- Artefakt <Bildgebende Diagnostik> (1)
- Artensterben (1)
- Artenvielfalt (1)
- Arterial Diameters (1)
- Arterial water (1)
- Arterie (1)
- Arterielles Blut (1)
- Arterioles (submucosal) (1)
- Artery (1)
- Artery Models (1)
- Artesunate (1)
- Arthrography (1)
- Arthroleptis amphibia (1)
- Arthropod (1)
- Arthropoda (1)
- Arthropodengemeinschaft (1)
- Arthropods (1)
- Arthrosis deformans (1)
- Arthur Hailey (1)
- Articular afferent (1)
- Articular-Cartilage (1)
- Articulation (1)
- Artificial Base Pair (1)
- Artificial Neural Networks (1)
- Artificial Nuclear Pores (1)
- Artificial photosynthesis (1)
- Artunterschiede (1)
- Artverbreitungsmodellierung (1)
- Aryl Halides (1)
- Aryl Hydrocarbon Hydroxylase (1)
- Aryl hydrocarbon rnonooxygenase (1)
- Arylborylene Complexes (1)
- Arzneimittelmarkt (1)
- Arzneimittelwechselwirkung (1)
- Arzneistoffanalytik (1)
- Asc-1 transporter (1)
- Ascaris lumbricoides (1)
- Aseptic loosening (1)
- Asia (1)
- Asian Englishes (1)
- Asisted Reproduction (1)
- Aspartate Aminotransferases (1)
- Aspergillose (1)
- Aspergillosis (1)
- Aspergillus fumigalus (1)
- Aspergillus medium (1)
- Aspergillus niger (1)
- Aspergillus sp. (1)
- Assay (1)
- Assemblages (1)
- Assistenzbedarf (1)
- Association study (1)
- AstA (1)
- Astrochemie (1)
- Astrocytes ; Schwann cells ; Interferon-gamma ; Fibroblast growth factor ; Cyclic AMP (1)
- Astrocytic tumor (1)
- Astronomie (1)
- Astronomische Beobachtung (1)
- Astrophysical Jet (1)
- Astrophysical neutrino sources (1)
- Astrophysics (1)
- Astroteilchenphysik (1)
- Astrozyten (1)
- Astrozytom (1)
- Asylpolitik (1)
- Asymmetric synthesis (1)
- Asymmetrie (1)
- Asymmetrische Information (1)
- Asymmetrische Synthese (1)
- Asymptomatic Bacteriuria (1)
- Asymptotic Preserving (1)
- Asymptotic independence (1)
- Atacama (1)
- Ataxia (1)
- Atemwegsschleimhaut (1)
- Atharvaveda (1)
- Atherosclerosis, intracranial arteries (1)
- Atherosclerotic plaque (1)
- Atmospheric muons (1)
- Atmosphäre (1)
- Atmungsinsuffizienz (1)
- Atom und Molekülphysik (1)
- Atomgitter (1)
- Atomic (1)
- Atomic force microscopy (1)
- Atomic-force-microscopy (1)
- Atomisierungsenergien (1)
- Atomketten (1)
- Atomphysik (1)
- Atria (1)
- Atrial fibrillation (1)
- Atrial natriuretic peptide (1)
- Atropisomere (1)
- Atropisomerie (1)
- Atta (1)
- Atta sexdens (1)
- Attention (1)
- Attention Deficit Hyperactivity Disorder (ADHD) (1)
- Attention deficit / hyperactivity disorder (1)
- Attentional performance (1)
- Attitude (1)
- Attitude Determination and Control (1)
- Attitude Dynamics (1)
- Attitude Heading Reference System (AHRS) (1)
- Attitudes towards immigrants (1)
- Attosekundenbereich (1)
- Attraction (1)
- Attraktion (1)
- Attraktor (1)
- Au/Ge(111) (1)
- AuNPs (1)
- Audiologie (1)
- Audiovisuelle Medien (1)
- Audit Quality (1)
- Auditing (1)
- Auditor Independence (1)
- Auditory pathway (1)
- Auditory targets (1)
- Aufgabenwechsel (1)
- Aufmerksamkeitsprozesse (1)
- Aufsatzsammlung (1)
- Auftauschicht (1)
- Augenkrankheit (1)
- Auger-Spektroskopie (1)
- Augmented Lagrangian (1)
- Augmented Lagrangian methods (1)
- Aulonocara (1)
- Aureobasidium (1)
- Aureobasidium pullulans (1)
- AurisID (1)
- Aurora B (1)
- Ausbeutung (1)
- Ausbreitungsdistanz (1)
- Ausbreitungsstrategie (1)
- Ausbreitungsverhalten (1)
- Ausgrabung (1)
- Ausländer (1)
- Ausschreibungen (1)
- Aussterbedynamik (1)
- Austauschaufspaltung (1)
- Australian stingless bees (1)
- Australien (1)
- Auswanderwahrscheinlichkeit (1)
- Autism (1)
- Autismus (1)
- Auto-antibodies (1)
- Autodetachment (1)
- Autofocus (1)
- Autoimmune diseases (1)
- Autoimmune-Diseases (1)
- Autoindustrie (1)
- Autoinflammation (1)
- Autoinhibition (1)
- Autologous (1)
- Automat <Automatentheorie> (1)
- Automata Theory (1)
- Automated Checkout (1)
- Automated Classification (1)
- Automated analysis (1)
- Automatentheorie (1)
- Automatic Text Reconition (1)
- Automatische Sprachanalyse (1)
- Automatische Texterkennung (ATR) (1)
- Automatisiertes Fahren (1)
- Automatization (1)
- Automobilindustrie (1)
- Automorphismengruppe (1)
- Automotive industry (1)
- Autonomes Fahrzeug (1)
- Autonomic Computing (1)
- Autonomie (1)
- Autonomous Robot (1)
- Autonomous multi-vehicle systems (1)
- Autoproteolysis (1)
- Autoradiographie (1)
- Autoreduzierbarkeit (1)
- Autoregulation (1)
- Autorotation (1)
- Autotransporter (1)
- Autökologie (1)
- AuxRE (1)
- Auxin-regulated transcription (1)
- Auxine (1)
- Außerschulische Bildung (1)
- Available soil water capacity (1)
- Aversive events (1)
- Aversive tension (1)
- Avionik (1)
- Aviophobia (1)
- Avirulent Salmonella (1)
- Avoidance (1)
- Avoidance behavior (1)
- Axl tyrosine kinase (1)
- Axon Branching (1)
- Axon growth (1)
- Axon guidance (1)
- Axonal transport (1)
- Axonschaden (1)
- Azathioprine (1)
- Aziridines (1)
- Azole (1)
- Azoles (1)
- Azospirillum brasilense (1)
- Aššur (1)
- Aδ- and C-fibers (1)
- B (1)
- B 37 CAG repeat locus (1)
- B Lymphocytes (1)
- B cell culture (1)
- B cell deficiency (1)
- B cell malignancies (1)
- B cell maturation (1)
- B cell receptor (1)
- B cell receptor (BCR) (1)
- B neisseria meningitidis (1)
- B physics (1)
- B,N-heterocycles (1)
- B,N-heterocylcles (1)
- B-0 (1)
- B-B bond (1)
- B-B bond activation (1)
- B-Lymphocyten (1)
- B-RAF (1)
- B-Zell-Leukämie (1)
- B-Zelldepletive Therapie (1)
- B-Zellen (1)
- B-Zellrepertoire (1)
Institute
- Theodor-Boveri-Institut für Biowissenschaften (1878)
- Graduate School of Life Sciences (780)
- Physikalisches Institut (579)
- Institut für Psychologie (484)
- Neurologische Klinik und Poliklinik (378)
- Institut für Organische Chemie (360)
- Medizinische Klinik und Poliklinik I (354)
- Institut für Anorganische Chemie (353)
- Medizinische Klinik und Poliklinik II (352)
- Institut für Molekulare Infektionsbiologie (346)
Schriftenreihe
- Cultural Animal Studies, Band 3 (24)
- Berichte aus der Informatik (1)
- Deuterocanonical and Cognate Literature Studies (1)
- Deuterocanonical and Cognate Literature Yearbook (1)
- International Archives of the History of Ideas / Archives internationales d’histoire des idées 242 (1)
- Methods in Molecular Biology 2533 (1)
- Methods in Molecular Biology; 2643 (1)
Sonstige beteiligte Institutionen
- VolkswagenStiftung (24)
- Johns Hopkins School of Medicine (17)
- IZKF Nachwuchsgruppe Geweberegeneration für muskuloskelettale Erkrankungen (7)
- Clinical Trial Center (CTC) / Zentrale für Klinische Studien Würzburg (ZKSW) (5)
- Fraunhofer-Institut für Silicatforschung ISC (5)
- Helmholtz Institute for RNA-based Infection Research (HIRI) (5)
- Johns Hopkins University School of Medicine (5)
- Wilhelm-Conrad-Röntgen-Forschungszentrum für komplexe Materialsysteme (5)
- Bernhard-Heine-Centrum für Bewegungsforschung (4)
- Johns Hopkins School of Medicine, Baltimore, MD, U.S. (4)
ResearcherID
- B-1911-2015 (1)
- B-4606-2017 (1)
- C-2593-2016 (1)
- D-1221-2009 (1)
- D-1250-2010 (1)
- I-5818-2014 (1)
- J-8841-2015 (1)
- M-1240-2017 (1)
- N-2030-2015 (1)
- N-3741-2015 (1)
Large-Scale Assessment of a Fully Automatic Co-Adaptive Motor Imagery-Based Brain Computer Interface
(2016)
In the last years Brain Computer Interface (BCI) technology has benefited from the development of sophisticated machine leaning methods that let the user operate the BCI after a few trials of calibration. One remarkable example is the recent development of co-adaptive techniques that proved to extend the use of BCIs also to people not able to achieve successful control with the standard BCI procedure. Especially for BCIs based on the modulation of the Sensorimotor Rhythm (SMR) these improvements are essential, since a not negligible percentage of users is unable to operate SMR-BCIs efficiently. In this study we evaluated for the first time a fully automatic co-adaptive BCI system on a large scale. A pool of 168 participants naive to BCIs operated the co-adaptive SMR-BCI in one single session. Different psychological interventions were performed prior the BCI session in order to investigate how motor coordination training and relaxation could influence BCI performance. A neurophysiological indicator based on the Power Spectral Density (PSD) was extracted by the recording of few minutes of resting state brain activity and tested as predictor of BCI performances. Results show that high accuracies in operating the BCI could be reached by the majority of the participants before the end of the session. BCI performances could be significantly predicted by the neurophysiological indicator, consolidating the validity of the model previously developed. Anyway, we still found about 22% of users with performance significantly lower than the threshold of efficient BCI control at the end of the session. Being the inter-subject variability still the major problem of BCI technology, we pointed out crucial issues for those who did not achieve sufficient control. Finally, we propose valid developments to move a step forward to the applicability of the promising co-adaptive methods.
Infants and young children (IYC) remain the most vulnerable population group to environmental hazards worldwide, especially in economically developing regions such as sub-Saharan Africa (SSA). As a result, several governmental and non-governmental institutions including health, environmental and food safety networks and researchers have been proactive toward protecting this group. Mycotoxins, toxic secondary fungal metabolites, contribute largely to the health risks of this young population. In SSA, the scenario is worsened by socioeconomic status, poor agricultural and storage practices, and low level of awareness, as well as the non-establishment and lack of enforcement of regulatory limits in the region. Studies have revealed mycotoxin occurrence in breast milk and other weaning foods. Of concern is the early exposure of infants to mycotoxins through transplacental transfer and breast milk as a consequence of maternal exposure, which may result in adverse health effects. The current paper presents an overview of mycotoxin occurrence in foods intended for IYC in SSA. It discusses the imperative evidence of mycotoxin exposure of this population group in SSA, taking into account consumption data and the occurrence of mycotoxins in food, as well as biomonitoring approaches. Additionally, it discusses the health implications associated with IYC exposure to mycotoxins in SSA.
Fungi possess diverse photosensory proteins that allow them to perceive different light wavelengths and to adapt to changing light conditions in their environment. The biological and physiological roles of the green light-sensing rhodopsins in fungi are not yet resolved. The rice plant pathogen Fusarium fujikuroi exhibits two different rhodopsins, CarO and OpsA. CarO was previously characterized as a light-driven proton pump. We further analyzed the pumping behavior of CarO by patch-clamp experiments. Our data show that CarO pumping activity is strongly augmented in the presence of the plant hormone indole-3-acetic acid and in sodium acetate, in a dose-dependent manner under slightly acidic conditions. By contrast, under these and other tested conditions, the Neurospora rhodopsin (NR)-like rhodopsin OpsA did not exhibit any pump activity. Basic local alignment search tool (BLAST) searches in the genomes of ascomycetes revealed the occurrence of rhodopsin-encoding genes mainly in phyto-associated or phytopathogenic fungi, suggesting a possible correlation of the presence of rhodopsins with fungal ecology. In accordance, rice plants infected with a CarO-deficient F. fujikuroi strain showed more severe bakanae symptoms than the reference strain, indicating a potential role of the CarO rhodopsin in the regulation of plant infection by this fungus.
Merkel Cell Carcinoma (MCC) is a rare and highly aggressive neuroendocrine skin cancer for which no effective treatment is available. MCC represents a human cancer with the best experimental evidence for a causal role of a polyoma virus. Large T antigens (LTA) encoded by polyoma viruses are oncoproteins, which are thought to require support of cellular heat shock protein 70 (HSP70) to exert their transforming activity. Here we evaluated the capability of MAL3-101, a synthetic HSP70 inhibitor, to limit proliferation and survival of various MCC cell lines. Remarkably, MAL3-101 treatment resulted in considerable apoptosis in 5 out of 7 MCC cell lines. While this effect was not associated with the viral status of the MCC cells, quantitative mRNA expression analysis of the known HSP70 isoforms revealed a significant correlation between MAL3-101 sensitivity and HSC70 expression, the most prominent isoform in all cell lines. Moreover, MAL3-101 also exhibited in vivo antitumor activity in an MCC xenograft model suggesting that this substance or related compounds are potential therapeutics for the treatment of MCC in the future.
Melanoma formation in the teleost Xiphophorus is caused by a dominant genetic locus, Tu. This locus includes the Xmrk oncogene, which encodes a receptor tyrosine kinase. Tumor induction is. suppressed in wild-type fish by a tumor suppressor locus, R. Molecular genetic analyses revealed that the Tu locus emerged by nonhomologaus recombination of the Xmrk proto-oncogene with a previously uncharacterized sequence, D. This event generated an additional copy of Xmrk with a new promoter. Suppression of the new Xmrk promoter by R in parental fish and its deregulation in hybrids explain the genetics of melanoma formation in Xiphophorus.
The melanoma inducing locus of Xiphophorus encodes a tumorigenic version of a novel putative receptor tyrosine kinase (Xmrk). To elucidate the mechanism of oncogenic activation of Xmrk, we compared the structure and expression of two oncogenic loci with the corresponding proto-oncogene. Only minor structural alterations were found to be specific for the oncogenic Xmrk genes. Marked overexpression of the oncogene transcripts in melanoma, which are approximately 1 kb shorter than the proto-oncogene transcript, correlates with the malignancy of the tumors. The tumor transcripts are derived from an alternative transcription start site that is used only in the oncogenic loci. Thus, oncogenic activation of the melanoma inducing Xmrk gene appears primarily to be due to novel transcriptional control and overexpression.
Background
Treatment options for poorly differentiated (PDTC) and anaplastic (ATC) thyroid carcinoma are unsatisfactory and prognosis is generally poor. Lenvatinib (LEN), a multi-tyrosine kinase inhibitor targeting fibroblast growth factor receptors (FGFR) 1-4 is approved for advanced radioiodine refractory thyroid carcinoma, but response to single agent is poor in ATC. Recent reports of combining LEN with PD-1 inhibitor pembrolizumab (PEM) are promising.
Materials and Methods
Primary ATC (n=93) and PDTC (n=47) tissue samples diagnosed 1997-2019 at five German tertiary care centers were assessed for PD-L1 expression by immunohistochemistry using Tumor Proportion Score (TPS). FGFR 1-4 mRNA was quantified in 31 ATC and 14 PDTC with RNAscope in-situ hybridization. Normal thyroid tissue (NT) and papillary thyroid carcinoma (PTC) served as controls. Disease specific survival (DSS) was the primary outcome variable.
Results
PD-L1 TPS≥50% was observed in 42% of ATC and 26% of PDTC specimens. Mean PD-L1 expression was significantly higher in ATC (TPS 30%) than in PDTC (5%; p<0.01) and NT (0%, p<0.001). 53% of PDTC samples had PD-L1 expression ≤5%. FGFR mRNA expression was generally low in all samples but combined FGFR1-4 expression was significantly higher in PDTC and ATC compared to NT (each p<0.001). No impact of PD-L1 and FGFR 1-4 expression was observed on DSS.
Conclusion
High tumoral expression of PD-L1 in a large proportion of ATCs and a subgroup of PDTCs provides a rationale for immune checkpoint inhibition. FGFR expression is low thyroid tumor cells. The clinically observed synergism of PEM with LEN may be caused by immune modulation.
1.2-Dioxetanes, very reactive and high energy molecules. are involved as labile intermediates in dioxygenase- activated aerobic metabolism and in physiological processes. Various toxico1ogica1 tests reveal that dioxetanes are indeed genotoxic. In supercoiled DNA of bacteriophage PM2 they induce endonucleasesensitive sites, most of them are FPG protein-sensitive base modifications (8-hydroxyguanine, fonnamidopyrimidines). Pyrimidinedimersand sites ofbase loss (AP sites) which were probed by UV endonuclease and exonuclease 111 are minor lesions in this system. While the alky1-substituted dioxetanes do not show any significant mutagenic activity in different Salmonella typhimurium strains, heteroarene dioxetanes such as benzofuran and furocoumarin dioxetanes are strongly mutagenic in S. typhimurium strain TA I 00. DNA adducts formed with an intermediary alkyJating agent appear to be responsible for the mutagenic activity of benzofuran dioxetane. We assume that the benzofuran epoxides, generated in situ from benzofuran dioxetanes by deoxygenation are the ultimate mutagens of the latter. since benzofuran epoxides are highly mutagenic in the S. typhimurium strain TAIOO and they form DNA adducts. as detected by the 212Ppostlabelling technique. Our results imply that the type of D NA darnage promoted by dioxetanes is dependent on the structural feature of dioxetanes. Furthermore, the direct photochemical DNA darnage by energy transfer. i.e., pyrimidine dimers, plays a minor role in the genotoxicity of dioxetanes. Instead, photooxidation dominates in isolated DNA. while radical darnage and alkylation prevail in the cellular system.
The idea that our observable Universe may have originated from a quantum tunneling event out of an eternally inflating false vacuum state is a cornerstone of the multiverse paradigm. Modern theories that are considered as an approach towards the ultraviolet-complete fundamental theory of particles and gravity, such as the various types of string theory, even suggest that a vast landscape of different vacuum configurations exists, and that gravitational tunneling is an important mechanism with which the Universe can explore this landscape. The tunneling scenario also presents a unique framework to address the initial conditions of our observable Universe. In particular, it allows to introduce deviations from the cosmological concordance model in a controlled and well-motivated way. These deviations are a central topic of this work. An important feature in most of the theories mentioned above is the presumed existence of additional space dimensions in excess of the three which we observe in our every-day experience. It was realized that these extra dimensions could avoid our detection if they are compactified to microscopic length scales far beyond the reach of current experiments. There also seem to be natural mechanisms available for dynamical compactification in those theories. These typically lead to a vast landscape of different vacuum configurations which also may differ in the number of macroscopic dimensions, only the total number of dimensions being determined by the theory. Transitions between these vacuum configurations may hence open up new directions which were previously compact, spontaneously compactify some previously macroscopic directions, or otherwise re-arrange the configuration of compact and macroscopic dimensions in a more general way. From within the bubble Universe, such a process may be perceived as an anisotropic background spacetime - intuitively, the dimensions which open up may give rise to preferred directions. If our 3+1 dimensional observable Universe was born in a process as described above, one may expect to find traces of a preferred direction in cosmological observations. For instance, two directions could be curved like on a sphere, while the third space direction is flat. Using a scenario of gravitational tunneling to fix the initial conditions, I show how the primordial signatures in such an anisotropic Universe can be obtained in principle and work out a particular example in more detail. A small deviation from isotropy also has phenomenological consequences for the later evolution of the Universe. I discuss the most important effects and show that backreaction can be dynamically important. In particular, under certain conditions, a buildup of anisotropic stress in different components of the cosmic fluid can lead to a dynamical isotropization of the total stress-energy tensor. The mechanism is again demonstrated with the help of a physical example.
In most foreign language learning contexts, there are only rare chance for contact with native speakers of the target language. In such a situation, reading plays an important role in language acquisition as well as in gaining cultural information about the target language and its speakers.
Previous research indicated that reading in foreign language is a complex process, which is influenced by various linguistic, cognitive and affective factors. The aim of the present study was to test two structural models of the relationship between reading comprehension in native language (L1), English language (L2) reading motivation, metacognitive awareness of L2 reading strategies, and reading comprehension of English as a foreign language among the two samples. Furthermore, the current study aimed to examine the differences between Egyptian and German students in their perceived usage of reading strategies during reading English texts, as well as to explore the pattern of their motivation toward reading English texts. For this purpose, 401 students were recruited from Germany (n=200) and Egypt (n=201) to participate in the current study. In order to have information about metacognitive awareness of reading strategies, a self-report questionnaire (SORS) developed by Moktari and Sheory (2002) was used. While the L2 reading motivation variable, was measured by a reading motivation survey (L2RMQ) which was based on reviewed reading motivation research. In addition, two reading tests were administrated one to measure reading comprehension for native language (German/Arabic) and the other to measure English reading comprehension.
To analyze the collected data, descriptive statistics and independent t-tests were performed. In addition, further analysis using structural equation modeling was applied to test the strength of relationships between the variables under study.
The results from the current research revealed that L1 reading comprehension, whether in a German or Arabic language, had the strongest relationship with L2 reading comprehension. However, the relationship between L2 intrinsic reading motivation was not proven to be significant in either the German or Egyptian models. On the other hand, the relationship between L2 extrinsic reading motivation, metacognitive awareness of reading strategies, and L2 reading comprehension was only proven significant in the German sample. The discussion of these results along with their pedagogical implications for education and practice will be illustrated in the following study.
Virotherapy on the basis of oncolytic vaccinia virus (VACV) strains is a novel approach for canine cancer therapy. Here we describe, for the first time, the characterization and the use of VACV strain GLV-5b451 expressing the anti-vascular endothelial growth factor (VEGF) single-chain antibody (scAb) GLAF-2 as therapeutic agent against different canine cancers. Cell culture data demonstrated that GLV-5b451 efficiently infected and destroyed all four tested canine cancer cell lines including: mammary carcinoma (MTH52c), mammary adenoma (ZMTH3), prostate carcinoma (CT1258), and soft tissue sarcoma (STSA-1). The GLV-5b451 virus-mediated production of GLAF-2 antibody was observed in all four cancer cell lines. In addition, this antibody specifically recognized canine VEGF. Finally, in canine soft tissue sarcoma (CSTS) xenografted mice, a single systemic administration of GLV-5b451 was found to be safe and led to anti-tumor effects resulting in the significant reduction and substantial long-term inhibition of tumor growth. A CD31-based immuno-staining showed significantly decreased neo-angiogenesis in GLV-5b451-treated tumors compared to the controls. In summary, these findings indicate that GLV-5b451 has potential for use as a therapeutic agent in the treatment of CSTS.
Virotherapy on the basis of oncolytic vaccinia virus (VACV) infection is a promising approach for cancer therapy. In this study we describe the establishment of a new preclinical model of feline mammary carcinoma (FMC) using a recently established cancer cell line, DT09/06. In addition, we evaluated a recombinant vaccinia virus strain, GLV-5b451, expressing the anti-vascular endothelial growth factor (VEGF) single-chain antibody (scAb) GLAF-2 as an oncolytic agent against FMC. Cell culture data demonstrate that GLV-5b451 virus efficiently infected, replicated in and destroyed DT09/06 cancer cells. In the selected xenografts of FMC, a single systemic administration of GLV-5b451 led to significant inhibition of tumor growth in comparison to untreated tumor-bearing mice. Furthermore, tumor-specific virus infection led to overproduction of functional scAb GLAF-2, which caused drastic reduction of intratumoral VEGF levels and inhibition of angiogenesis.
In summary, here we have shown, for the first time, that the vaccinia virus strains and especially GLV-5b451 have great potential for effective treatment of FMC in animal model.
We quantify the contemporaneous relationships among stock markets in the euro area, the United States, and a group of emerging economies over the period from 2008 to 2017. Exploiting the heteroskedasticity in the stock market data, we identify shocks that originated in the respective domestic markets and shocks that are common to all markets. Our results underline the leading role of the United States in international equity markets, but also point to the importance of indirect spillovers for all economies. Variance decompositions show that while domestic shocks explain the bigger part of the variation in each stock market, a substantial part of the variation in the euro area and the emerging economies can be attributed to foreign shocks. A comparison with a sample covering the pre‐crisis period from 1999 to 2007 suggests a strengthening of the linkages among global stock markets in recent years. In particular, the spillovers from advanced to emerging economies have become more pronounced.
The putative attachment protein G of pneumonia virus of mice (PVM), a member of the Pneumoviruses, is an important virulence factor with so far ambiguous function in a virus-cell as well as in virus-host context. The sequence of the corresponding G gene is characterized by significant heterogeneity between and even within strains, affecting the gene and possibly the protein structure. This accounts in particular for the PVM strain J3666 for which two differing G gene organizations have been described: a polymorphism in nucleotide 65 of the G gene results in the presence of an upstream open reading frame (uORF) that precedes the main ORF in frame (GJ366665A) or extension of the major G ORF for 18 codons (GJ366665U). Therefore, this study was designed to analyse the impact of the sequence variations in the respective G genes of PVM strains J3666 and the reference strain 15 on protein expression, replication and virulence.
First, the controversy regarding the consensus sequence of PVM J3666 was resolved. The analysis of 45 distinct cloned fragments showed that the strain separated into two distinct virus populations defined by the sequence and structure of the G gene. This division was further supported by nucleotide polymorphisms in the neighbouring M and SH genes. Sequential passage of this mixed strain in the cell line standardly used for propagation of virus stocks resulted in selection for the GJ366665A-containing population in one of two experiments pointing towards a moderate replicative advantage. The replacement of the G gene of the recombinant PVM 15 with GJ366665A or GJ366665U, respectively, using a reverse genetic approach indicated that the presence of uORF within the GJ366665A significantly reduced the expression of the main G ORF on translational level while the potential extension of the ORF in GJ366665U increased G protein expression. In comparison, the effect of the G gene-structure on virus replication was inconsistent and dependent on cell line and type. While the presence of uORF correlated with a replication advantage in the standardly used BHK-21 cells and primary murine embryonic fibroblasts, replication in the murine macrophage cell line RAW 264.7 did not. In comparison, the GJ366665U variant was not associated with any effect on replication in cultured cells at all. Nonetheless, in-vivo analysis of the recombinant viruses associated the GJ366665U gene variant, and hence an increased G expression, with higher virulence whereas the GJ366665A gene, and therefore an impaired G expression, conferred an attenuated phenotype to the virus.
To extend the study to other G gene organizations, a recombinant PVM expressing a G protein without the cytoplasmic domain and for comparison a G-deletion mutant, both known to be attenuated in vivo, were studied. Not noticed before, this structure of the G gene was associated with a 75% reduction in G protein expression and a significant attenuation of replication in macrophage-like cells. This attenuation was even more prominent for the virus lacking G. Taking into consideration the higher reduction in G protein levels compared to the GJ366665A variant indicates that a threshold amount of G is required for efficient replication in these cells.
In conclusion, the results gathered indicated that the expression levels of the G protein were modulated by the sequence of the 5’ untranslated region of the gene. At the same time the G protein levels modulated the virulence of PVM.
Cardio-respiratory changes and mortality in the conscious rat induced by (+)- and (±)- anatoxin-a
(1992)
0. M. ADEYEMO and A.-L. SIREN. Cardio-respiratory changes and mortality in the conscious rat induced by ( + )- and ( ± )-anatoxin-a. Toxicon 30, 899-905, 1992.-Anatoxin-a (AnTx-a) isapotent nicotinic cholinergic receptor agonist. The relative potencies of the ( + )-AnTx-a and the racemic mixture ( ± )-AnTxa were investigated in the conscious rat by comparing their effects on mean arterial blood pressure (BP), heart rate (HR), blood oxygen and carbon dioxide pressures (p02 and pC02, respective1y), acid-base balance (pH) and mortality. The present experiments show that while both forms of AnTx-a produce dose-dependent increases in BP and decreases in HR, ( + )-AnTx-a is about IO-fo1d morepotent than the optically inactive isomer. ( + )-AnTx-a was also 6-fo1d more potent than ( ± )-AnTx-a in produclog severe hypoxemia, and more than 4-fold as potent as the (±}-AnTx-a in producing significant hypercapnia accompanied with severe acidosis. The approximate median Iethai dose (Ln so) of ( + )-AnTx-a was about 5-fold less than that of ( ± )-AnTx-a. We conclude that ( + )-AnTx-a is more potent than the ( ± )-AnTx-a racemic mixture in causing detrimental cardio-respiratory changes and therefore increased mortality in the rat.
A Goldfish Model for Evaluation of the Neurotaxicity of \(\omega\)-Conotoxin GVI A and Screening of Monoclonal Antibodies. ADEYEMO, 0. M .. SHAPIRA, S., TOMBACCINI, D., POLLARD, H. 8 .• FEUERSTEIN, G .. AND SIREN, A-L. ( 1991 ). Toxicol. App/. Pharmaco/. 108, 489-496. The neurotoxicity of \(\omega\)-conotoxin (\(\omega\)-CgTx), a potent neuronal voltage-sensitive calcium channel blocker, was measured using a new bioassay. \(\omega\)-CgTx was administered intraperitoneally (ip) to goldfish weighing approximately 1.6 g, and dose-related changes were observed over a 2-hr period. \(\omega\)CgTx induced time- and dose-dependent abnormal swimming behavior (ASB) and mortality. The antitoxin activity of the antiborlies was investigated in vivo by either ( l) preincubation of the antibody with w-CgTx at 4°C overnight, or (2) pretreatment with antibody, 30 min before \(\omega\)CgTx injection in a 10:1 antibody/\(\omega\)-CgTx molar ratio. The LD50 dose of \(\omega\)-CgTx in goldfish was 5 nmol/kg ip, and preincubation of monoclonal antibody (50 nmol/kg ip) with \(\omega\)-CgTx (5 nmol/kg ip) significantly (p < 0.05) reduced mortality. ASB, and toxicity time. The antitoxin activity of the monoclonal antiborlies evidenced in the goldfish bioassay was further tested in the conscious rat. In the rat, the increases in mean arterial pressure and heart rate induced by \(\omega\)-CgTx (0.03 nmol/rat icv) were significantly (p < 0.02 and p < 0.0 l, respectively) attenuated by preincubation of the toxin with the antibody (0.3 nmol/rat). We conclude that the goldfish bioassay provides a simple. accurate, and inexpensive in vivo model for the study of the toxicity of \(\omega\)CgTx
The hallmark oncoprotein Myc is a major driver of tumorigenesis in various human cancer entities. However, Myc’s structural features make it challenging to develop small molecules against it. A promising strategy to indirectly inhibit the function of Myc is by targeting its interactors. Many Myc-interacting proteins have reported scaffolding functions which are difficult to target using conventional occupancy- driven inhibitors. Thus, in this thesis, the proteolysis targeting chimera (PROTAC) approach was used to target two oncoproteins interacting with Myc which promote the oncogenicity of Myc, Aurora-A and WDR5. PROTACs are bifunctional small molecules that bind to the target protein with one ligand and recruit a cellular E3- ligase with the other ligand to induce target degradation via the ubiquitin- proteasome system. So far, the most widely used E3-ligases for PROTAC development are Cereblon (CRBN) and von Hippel–Lindau tumor suppressor (VHL). Furthermore, there are cases of incompatibility between some E3-ligases and proteins to bring about degradation. Hence there is a need to explore new E3- ligases and a demand for a tool to predict degradative E3-ligases for the target protein in the PROTAC field.
In the first part, a highly specific mitotic kinase Aurora-A degrader, JB170, was developed. This compound utilized Aurora-A inhibitor alisertib as the target ligand and thalidomide as the E3-ligase CRBN harness. The specificity of JB170 and the ternary complex formation was supported by the interactions between Aurora-A and CRBN. The PROTAC-mediated degradation of Aurora-A induced a distinct S- phase defect rather than mitotic arrest, shown by its catalytic inhibition. The finding demonstrates that Aurora-A has a non-catalytic role in the S-phase. Furthermore, the degradation of Aurora-A led to apoptosis in various cancer cell lines.
In the second part, two different series of WDR5 PROTACs based on two protein- protein inhibitors of WDR5 were evaluated. The most efficient degraders from both series recruited VHL as a E3-ligase and showed partial degradation of WDR5. In addition, the degradation efficiency of the PROTACs was significantly affected by the linker nature and length, highlighting the importance of linker length and composition in PROTAC design. The degraders showed modest proliferation defects at best in cancer cell lines. However, overexpression of VHL increased the degradation efficiency and the antiproliferative effect of the PROTACs.
In the last part, a rapamycin-based assay was developed to predict the degradative E3-ligase for a target. The assay was validated using the WDR5/VHL and Aurora- A/CRBN pairs. The result that WDR5 is degraded by VHL but not CRBN and Aurora-A is degraded by CRBN, matches observations made with PROTACs. This technique will be used in the future to find effective tissue-specific and essential E3-ligases for targeted degradation of oncoproteins using PROTACs.
Collectively, the work presented here provides a strategy to improve PROTAC development and a starting point for developing Aurora-A and WDR5 PROTACs for cancer therapy.
Two-dimensional triangular lattices of group IV adatoms on semiconductor substrates provide a rich playground for the investigation of Mott-Hubbard physics. The possibility to combine various types of adatoms and substrates makes members of this material class versatile model systems to study the influence of correlation strength, band filling and spin-orbit coupling on the electronic structure - both experimentally and with dedicated many-body calculation techniques. The latter predict exotic ground states such as chiral superconductivity or spin liquid behavior for these frustrated lattices, however, experimental confirmation is still lacking. In this work, three different systems, namely the \(\alpha\)-phases of Sn/SiC(0001), Pb/Si(111), and potassium-doped Sn/Si(111) are investigated with scanning tunneling microscopy and photoemission spectroscopy in this regard. The results are potentially relevant for spintronic applications or quantum computing.
For the novel group IV triangular lattice Sn/SiC(0001), a combined experimental and theoretical study reveals that the system features surprisingly strong electronic correlations because they are boosted by the substrate through its partly ionic character and weak screening capabilities. Interestingly, the spectral function, measured for the first time via angle-resolved photoemission, does not show any additional superstructure beyond the intrinsic \(\sqrt{3} \times \sqrt{3} R30^{\circ}\) reconstruction, thereby raising curiosity regarding the ground-state spin pattern.
For Pb/Si(111), preceding studies have noted a phase transition of the surface reconstruction from \(\sqrt{3} \times \sqrt{3} R30^{\circ}\) to \(3 \times 3\) at 86 K. In this thesis, investigations of the low-temperature phase with high-resolution scanning tunneling microscopy and spectroscopy unveil the formation of a charge-ordered ground state. It is disentangled from a concomitant structural rearrangement which is found to be 2-up/1-down, in contrast to previous predictions. Applying an extended variational cluster approach, a phase diagram of local and nonlocal Coulomb interactions is mapped out. Based on a comparison of theoretical spectral functions with scattering vectors found via quasiparticle interference, Pb/Si(111) is placed in said phase diagram and electronic correlations are found to be the driving force of the charge-ordered state.
In order to realize a doped Mott insulator in a frustrated geometry, potassium was evaporated onto the well-known correlated Sn/Si(111) system. Instead of the expected insulator-to-metal transition, scanning tunneling spectroscopy data indicates that the electronic structure of Sn/Si(111) is only affected locally around potassium atoms while a metallization is suppressed. The potassium atoms were found to be adsorbed on empty \(T_4\) sites of the substrate which eventually leads to the formation of two types of K-Sn alloys with a relative potassium content of 1/3 and 1/2, respectively. Complementary measurements of the spectral function via angle-resolved photoemission reveal that the lower Hubbard band of Sn/Si(111) gradually changes its shape upon potassium deposition. Once the tin and potassium portion on the surface are equal, this evolution is complete and the system can be described as a band insulator without the need to include Coulomb interactions.
The high failure rate of new drug candidates in preclinical or clinical studies due to hepatotoxicity represents a considerable problem in the drug development. Hence, there is an urgent need to develop new approaches for early and reliable prediction of drug-induced hepatotoxicity that enables a better identification of drug candidates with high potential for toxicity at early stages of drug development. Therefore, the aim of this work was to improve the prediction of drug-induced liver injury in preclinical studies through evaluation of more reliable and sensitive biomarkers of hepatotoxicity and a better understanding of the underlying mechanistic basis for drug-induced toxicity. First, the ability of a set of potential markers (NGAL, thiostatin, clusterin, PON1) to detect early signs of liver injury was assessed in rats treated with drug candidates that were dropped from further development, in part due to toxic adverse effects in the liver. In summary, PON1 and clusterin were not consistently altered in response to liver injury and thus provide no additive information to the traditional liver enzymes in detecting drug-induced hepatotoxicity. In contrast, thiostatin and NGAL were increased in serum and urine of treated animals in a time- and dose-dependent manner. These changes correlated well with mRNA expression in the target organ and generally reflected the onset and degree of drug-induced liver injury. Receiver-operating characteristics analyses supported serum thiostatin, but not NGAL, as a better indicator of drug-induced hepatobiliary injury than conventional clinical chemistry parameters, such as ALP, ALT and AST. Although thiostatin, an acute phase protein expressed in a range of tissues, may not be specific for liver injury, our results indicate that thiostatin may serve as a sensitive, minimally-invasive diagnostic marker of inflammation and tissue damage in preclinical safety assessment. In the second part of this work, combined application of genomics profiling technology and RNAi to inhibit the pharmacological target of a drug candidate BAY16, a glucagon receptor (GCGR) antagonist, was used to determine if interference with the pharmacological target plays a role in the toxic response to BAY16, and to narrow down those molecular changes that are associated with toxicity, and not the pharmacological action of BAY16. In contrast to Bay 16, which was found to be cytotoxic at concentrations of 75 µM, silencing of the glucagon receptor did not affect cell viability in primary rat hepatocytes. Thus, it can be concluded that hepatotoxicity of Bay 16 was not related to the drugs inhibitory effect on the glucagon receptor in vitro and in vivo. These findings were supported by the fact that most of BAY16-induced changes in gene expression occurred independently of the pharmacological modulation of GCGR. These off-target effects include altered xenobiotic metabolism, oxidative stress, increased fatty acid synthesis, and alterations in cholesterol and bile acid metabolic processes. Although it was not possible to draw a final conclusion about the mechanism of BAY16 hepatotoxicity, changes in these molecular mechanisms appear contribute to progression of hepatic injury. With regard to drug safety assessment in preclinical studies, the utilization of siRNA technology in vitro represents a new approach to improve mechanistic understanding of the nature of drug’s toxicity, being either chemically mediated or due to primary or secondary pharmacological mode of action.
Context
Primary aldosteronism (PA) is the most frequent form of endocrine hypertension. Besides its deleterious impact on cardiovascular target organ damage, PA is considered to cause osteoporosis.
Patients and methods
We assessed bone turnover in a subset of 36 postmenopausal women with PA. 18 patients had unilateral PA and were treated by adrenalectomy, whereas 18 patients had bilateral PA and received mineralocorticoid receptor antagonist (MRA) therapy respectively. 18 age- and BMI-matched females served as controls. To estimate bone remodeling, we measured the bone turnover markers intact procollagen 1 N-terminal propeptide, bone alkaline phosphatase, osteocalcin and tartrate resistant acid phosphatase 5b in plasma by chemiluminescent immunoassays at time of diagnosis and one year after initiation of treatment.
Study design
Observational longitudinal cohort study.
Setting
Tertiary care hospital.
Results
Compared with controls, patients with PA had mildly elevated osteocalcin at baseline (p = 0.013), while the other bone markers were comparable between both groups. There were no differences between the unilateral and the bilateral PA subgroup. One year after initiation of MRA treatment with spironolactone bone resorption and bone formation markers had significantly decreased in patients with bilateral PA. In contrast, patients adrenalectomized because of unilateral PA showed no significant change of bone turnover markers.
Conclusion
This study shows that aldosterone excess in postmenopausal women with PA is not associated with a relevant increase of bone turnover markers at baseline. However, we observed a significant decrease of bone markers in patients treated with spironolactone, but not in patients treated by adrenalectomy.
Background
The dmrt1 and sox9 genes have a well conserved function related to testis formation in vertebrates, and the group of fish presents a great diversity of species and reproductive mechanisms. The lambari fish (Astyanax altiparanae) is an important Neotropical species, where studies on molecular level of sex determination and gonad maturation are scarce.
Methods
Here, we employed molecular cloning techniques to analyze the cDNA sequences of the dmrt1 and sox9 genes, and describe the expression pattern of those genes during development and the male reproductive cycle by qRT-PCR, and related to histology of the gonad.
Results
Phylogenetic analyses of predicted amino acid sequences of dmrt1 and sox9 clustered A. altiparanae in the Ostariophysi group, which is consistent with the morphological phylogeny of this species. Studies of the gonad development revealed that ovary formation occurred at 58 days after hatching (dah), 2 weeks earlier than testis formation. Expression studies of sox9 and dmrt1 in different tissues of adult males and females and during development revealed specific expression in the testis, indicating that both genes also have a male-specific role in the adult. During the period of gonad sex differentiation, dmrt1 seems to have a more significant role than sox9. During the male reproductive cycle dmrt1 and sox9 are down-regulated after spermiation, indicating a role of these genes in spermatogenesis.
Conclusions
For the first time the dmrt1 and sox9 were cloned in a Characiformes species. We show that both genes have a conserved structure and expression, evidencing their role in sex determination, sex differentiation and the male reproductive cycle in A. altiparanae. These findings contribute to a better understanding of the molecular mechanisms of sex determination and differentiation in fish.
Arapaima gigas is one of the largest freshwater fish species of high ecological and economic importance. Overfishing and habitat destruction are severe threats to the remaining wild populations. By incorporating a chromosomal Hi-C contact map, we improved the arapaima genome assembly to chromosome-level, revealing an unexpected high degree of chromosome rearrangements during evolution of the bonytongues (Osteoglossiformes). Combining this new assembly with pool-sequencing of male and female genomes, we identified id2bbY, a duplicated copy of the inhibitor of DNA binding 2b (id2b) gene on the Y chromosome as candidate male sex-determining gene. A PCR-test for id2bbY was developed, demonstrating that this gene is a reliable male-specific marker for genotyping. Expression analyses showed that this gene is expressed in juvenile male gonads. Its paralog, id2ba, exhibits a male-biased expression in immature gonads. Transcriptome analyses and protein structure predictions confirm id2bbY as a prime candidate for the master sex-determiner. Acting through the TGF beta signaling pathway, id2bbY from arapaima would provide the first evidence for a link of this family of transcriptional regulators to sex determination. Our study broadens our current understanding about the evolution of sex determination genetic networks and provide a tool for improving arapaima aquaculture for commercial and conservation purposes.
Sex determination (SD) is a highly diverse and complex mechanism. In vertebrates, one of the first morphological differences between the sexes is the timing of initiation of the first meiosis, where its initiation occurs first in female and later in male. Thus, SD is intimately related to the responsiveness of the germ cells to undergo meiosis in a sex-specific manner. In some vertebrates, it has been reported that the timing for meiosis entry would be under control of retinoic acid (RA), through activation of Stra8. In this study, we used a fish model species for sex determination and lacking the stra8 gene, the Japanese medaka (Oryzias latipes), to investigate the connection between RA and the sex determination pathway. Exogenous RA treatments act as a stress factor inhibiting germ cell differentiation probably by activation of dmrt1a and amh. Disruption of the RA degrading enzyme gene cyp26a1 induced precocious meiosis and oogenesis in embryos/hatchlings of female and even some males. Transcriptome analyzes of cyp26a1–/–adult gonads revealed upregulation of genes related to germ cell differentiation and meiosis, in both ovaries and testes. Our findings show that germ cells respond to RA in a stra8 independent model species. The responsiveness to RA is conferred by sex-related genes, restricting its action to the sex differentiation period in both sexes.
In vertebrates, one of the first recognizable sex differences in embryos is the onset of meiosis, known to be regulated by retinoic acid (RA) in mammals. We investigated in medaka a possible meiotic function of RA during the embryonic sex determination (SD) period and in mature gonads. We found RA mediated transcriptional activation in germ cells of both sexes much earlier than the SD stage, however, no such activity during the critical stages of SD. In adults, expression of the RA metabolizing enzymes indicates sexually dimorphic RA levels. In testis, RA acts directly in Sertoli, Leydig and pre-meiotic germ cells. In ovaries, RA transcriptional activity is highest in meiotic oocytes. Our results show that RA plays an important role in meiosis induction and gametogenesis in adult medaka but contrary to common expectations, not for initiating the first meiosis in female germ cells at the SD stage.
Systemic chemotherapy of pediatric recurrent ependymomas: results from the German HIT-REZ studies
(2021)
Purpose
Survival in recurrent ependymoma (EPN) depends mainly on the extent of resection achieved. When complete resection is not feasible, chemotherapy is often used to extend progression-free and overall survival. However, no consistent effect of chemotherapy on survival has been found in patients with recurrent EPN.
Methods
Systemic chemotherapeutic treatment of 138 patients enrolled in the German HIT-REZ-studies was analyzed. Survival depending on the use of chemotherapy, disease-stabilization rates (RR), duration of response (DOR) and time to progression (TTP) were estimated.
Results
Median age at first recurrence was 7.6 years (IQR: 4.0–13.6). At first recurrence, median PFS and OS were 15.3 (CI 13.3–20.0) and 36.9 months (CI 29.7–53.4), respectively. The Hazard Ratio for the use of chemotherapy in local recurrences in a time-dependent Cox-regression analysis was 0.99 (CI 0.74–1.33). Evaluable responses for 140 applied chemotherapies were analyzed, of which sirolimus showed the best RR (50%) and longest median TTP [11.51 (CI 3.98; 14.0) months] in nine patients, with the strongest impact found when sirolimus was used as a monotherapy. Seven patients with progression-free survival > 12 months after subtotal/no-resection facilitated by chemotherapy were found. No definitive survival advantage for any drug in a specific molecularly defined EPN type was found.
Conclusion
No survival advantage for the general use of chemotherapy in recurrent EPN was found. In cases with incomplete resection, chemotherapy was able to extend survival in individual cases. Sirolimus showed the best RR, DOR and TTP out of all drugs analyzed and may warrant further investigation.
The main objectives of the KM3NeT Collaboration are (i) the discovery and subsequent observation of high-energy neutrino sources in the Universe and (ii) the determination of the mass hierarchy of neutrinos. These objectives are strongly motivated by two recent important discoveries, namely: (1) the high-energy astrophysical neutrino signal reported by IceCube and (2) the sizable contribution of electron neutrinos to the third neutrino mass eigenstate as reported by Daya Bay, Reno and others. To meet these objectives, the KM3NeT Collaboration plans to build a new Research Infrastructure consisting of a network of deep-sea neutrino telescopes in the Mediterranean Sea. A phased and distributed implementation is pursued which maximises the access to regional funds, the availability of human resources and the synergistic opportunities for the Earth and sea sciences community. Three suitable deep-sea sites are selected, namely off-shore Toulon (France), Capo Passero (Sicily, Italy) and Pylos (Peloponnese, Greece). The infrastructure will consist of three so-called building blocks. A building block comprises 115 strings, each string comprises 18 optical modules and each optical module comprises 31 photo-multiplier tubes. Each building block thus constitutes a three-dimensional array of photo sensors that can be used to detect the Cherenkov light produced by relativistic particles emerging from neutrino interactions. Two building blocks will be sparsely configured to fully explore the IceCube signal with similar instrumented volume, different methodology, improved resolution and
A highly significant excess of high-energy astrophysical neutrinos has been reported by the IceCube Collaboration. Some features of the energy and declination distributions of IceCube events hint at a North/South asymmetry of the neutrino flux. This could be due to the presence of the bulk of our Galaxy in the Southern hemisphere. The ANTARES neutrino telescope, located in the Mediterranean Sea, has been taking data since 2007. It offers the best sensitivity to muon neutrinos produced by galactic cosmic ray interactions in this region of the sky. In this letter a search for an extended neutrino flux from the Galactic Ridge region is presented. Different models of neutrino production by cosmic ray propagation are tested. No excess of events is observed and upper limits for different neutrino flux spectral indices Γ are set. For Γ=2.4 the 90% confidence level flux upper limit at 100 TeV for one neutrino flavour corresponds to Φ\(^{1f}_{0}\) (100 TeV) = 2.0 · 10\(^{−17}\) GeV\(^{−1}\) cm\(^{−2}\)s\(^{−1}\)sr\(^{−1}\). Under this assumption, at most two events of the IceCube cosmic candidates can originate from the Galactic Ridge. A simple power-law extrapolation of the Fermi-LAT flux to account for IceCube High Energy Starting Events is excluded at 90% confidence level.
A search for high-energy neutrino emission correlated with gamma-ray bursts outside the electromagnetic prompt-emission time window is presented. Using a stacking approach of the time delays between reported gamma-ray burst alerts and spatially coincident muon-neutrino signatures, data from the Antares neutrino telescope recorded between 2007 and 2012 are analysed. One year of public data from the IceCube detector between 2008 and 2009 have been also investigated. The respective timing profiles are scanned for statistically significant accumulations within 40 days of the Gamma Ray Burst, as expected from Lorentz Invariance Violation effects and some astrophysical models. No significant excess over the expected accidental coincidence rate could be found in either of the two data sets. The average strength of the neutrino signal is found to be fainter than one detectable neutrino signal per hundred gamma-ray bursts in the Antares data at 90% confidence level.
A search for Secluded Dark Matter annihilation in the Sun using 2007-2012 data of the ANTARES neutrino telescope is presented. Three different cases are considered: a) detection of dimuons that result from the decay of the mediator, or neutrino detection from: b) mediator that decays into a dimuon and, in turn, into neutrinos, and c) mediator that decays directly into neutrinos. As no significant excess over background is observed, constraints are derived on the dark matter mass and the lifetime of the mediator.
A search for muon neutrinos originating from dark matter annihilations in the Sun is performed using the data recorded by the ANTARES neutrino telescope from 2007 to 2012. In order to obtain the best possible sensitivities to dark matter signals, an optimisation of the event selection criteria is performed taking into account the background of atmospheric muons, atmospheric neutrinos and the energy spectra of the expected neutrino signals. No significant excess over the background is observed and 90% C.L. upper limits on the neutrino flux, the spin-dependent and spin-independent WIMP-nucleon cross-sections are derived for WIMP masses ranging from 50 GeV to 5 TeV for the annihilation channels WIMP + WIMP→ b\(\overline{b}\), W\(^{+}\)W\(^{−}\) and τ\(^{+}\)τ\(^{−}\).
With an increasing variety of radiopharmaceuticals for diagnostic or therapeutic nuclear medicine as valuable diagnostic or treatment option, radiobiology plays an important role in supporting optimizations. This comprises particularly safety and efficacy of radionuclide therapies, specifically tailored to each patient. As absorbed dose rates and absorbed dose distributions in space and time are very different between external irradiation and systemic radionuclide exposure, distinct radiation-induced biological responses are expected in nuclear medicine, which need to be explored. This calls for a dedicated nuclear medicine radiobiology. Radiobiology findings and absorbed dose measurements will enable an improved estimation and prediction of efficacy and adverse effects. Moreover, a better understanding on the fundamental biological mechanisms underlying tumor and normal tissue responses will help to identify predictive and prognostic biomarkers as well as biomarkers for treatment follow-up. In addition, radiobiology can form the basis for the development of radiosensitizing strategies and radioprotectant agents. Thus, EANM believes that, beyond in vitro and preclinical evaluations, radiobiology will bring important added value to clinical studies and to clinical teams. Therefore, EANM strongly supports active collaboration between radiochemists, radiopharmacists, radiobiologists, medical physicists, and physicians to foster research toward precision nuclear medicine.
Optimal open-loop control, i.e. the application of an analytically derived control rule, is demonstrated for nanooptical excitations using polarization-shaped laser pulses. Optimal spatial near-field localization in gold nanoprisms and excitation switching is realized by applying a shift to the relative phase of the two polarization components. The achieved near-field switching confirms theoretical predictions, proves the applicability of predefined control rules in nanooptical light–matter interaction and reveals local mode interference to be an important control mechanism.
Radiationless energy transfer is at the core of diverse phenomena, such as light harvesting in photosynthesis\(^1\), energy-transfer-based microspectroscopies\(^2\), nanoscale quantum entanglement\(^3\) and photonic-mode hybridization\(^4\). Typically, the transfer is efficient only for separations that are much shorter than the diffraction limit. This hampers its application in optical communication and quantum information processing, which require spatially selective addressing. Here, we demonstrate highly efficient radiationless coherent energy transfer over a distance of twice the excitation wavelength by combining localized and delocalized\(^5\) plasmonic modes. Analogous to the Tavis-Cummings model, two whispering-gallery-mode antennas\(^6\) placed in the foci of an elliptical plasmonic cavity\(^7\) fabricated from single-crystal gold plates act as a pair of oscillators coupled to a common cavity mode. Time-resolved two-photon photoemission electron microscopy (TR 2P-PEEM) reveals an ultrafast long-range periodic energy transfer in accordance with the simulations. Our observations open perspectives for the optimization and tailoring of mesoscopic energy transfer and long-range quantum emitter coupling.
The aim of the present study was to design different dosage forms as carrier systems to deliver sorafenib to the lung of BXB-23 transgenic mice using different routes of administration. Three dosage forms were used one of them was an oil-in-water emulsion and the oral route was chosen for this experiment. The other delivery system was a liposome preparation for intratracheal instillation. In this case the oral route was considered as a control experiment. The last dosage form was PLGA microspheres. Before sorafenib administration it was important to develop a HPLC method to assess sorafenib absorption after its administration and to determine its concentrations in mouse serum. The HPLC method allowed sorafenib quantification in small volumes (30 µl) of mouse serum and tissues. The developed HPLC method was validated resulting in satisfactory selectivity, good linearity, good accuracy and precision over the concentration range examined. Sorafenib was successfully incorporated in a fat emulsion (o/w) using a traditional method resulting in a white homogenous emulsion and no particle aggregation was observed. Sorafenib exhibited antitumor activity on the lung adenoma in BXB-23 transgenic mice when administered orally (2 mg sorafenib per mouse) in the emulsion preparation. The determined effect was an approximately 29 % reduction in the tumor area of the adenoma foci and a proliferation reduction. In order to improve the pharmacological effects of sorafenib on the lung adenoma in BXB-23 mice, the targeting of sorafenib directly to the site of action (the lung) was an attractive concept. For this purpose the intratracheal route was used. Since sorafenib administration by instillation required incorporation of sorafenib in a dosage form suitable for its lipophilic nature, a liposome suspension was the second dosage form used. A lyophilization method was employed for sorafenib liposome preparation utilizing dilauroylphosphatidylcholine (DLPC) which is safe and tolerable for the lung. Incorporation of sorafenib in the liposomes did not influence the particle size and its distribution. The sorafenib liposomes showed high encapsulation efficiency, good stability at 4 °C for one month and satisfactory in vitro release properties and inhibited Raf-1 mediated activation of ERK in cell culture assay. In a pharmacokinetic experiment sorafenib loaded liposomes were instilled directly into the lung. The results revealed that a significant level of sorafenib was achieved in the lung tissues after 2 hours and then reduced after 48 h and remained nearly constant for one week. On the other hand, only traces of sorafenib were found in the mice serum up to 48 h. Subsequently, the pharmacological activity of sorafenib (1 mg per mouse) was studied when delivered in a liposomal suspension intratracheally to treat the lung adenoma of BXB-23 mice. The data of this experiment demonstrated that sorafenib intratracheal instillation resulted in a reduction of tumor area of adenoma foci (67 %) and an elevation of the percent of apoptotic cells. In contrast, prolongation of the treatment period did not further enhance sorafenib activity on the lung adenoma. This previous finding suggested a development of multidrug resistance (MDR) by the adenoma foci cells against sorafenib instillation, which was examined by immunohistochemistry staining. The percent of MDR positive cells was higher after two and three weeks sorafenib liposome instillation treatment than that after one week treatment. The last dosage form used for sorafenib was microspheres, which were prepared by emulsion-diffusion-evaporation method using biodegradable PLGA 50:50 resulting in a white lyophilized powder. The system was characterized physicochemically and revealed a good microspheres yield, high encapsulation efficiency, a homogenous particle size distribution and slow in vitro release of sorafenib. The other strategy studied in the present research project was gene delivery to target the lung bearing tumor of BXB-23 mice using a non-viral vector (polyethylenimine). Polyethylenimine (PEI) was used to investigate its efficiency in transfecting lung bearing tumor of BXB-23 mice model and its ability to transfect the adenoma foci cells. LacZ, which encodes Beta-galactosidase was used in the present study as a reporter gene and was complexed with PEI before delivered intravenously. A high LacZ expression in the alveolar region with some expression in the adenoma foci was observed. On contrary, a low LacZ expression in the alveoli and in the adenoma foci was achieved after instillation of the same polyplex intratracheally.
Background:
The interaction of eukaryotic host and prokaryotic pathogen cells is linked to specific changes in the cellular proteome, and consequently to infection-related gene expression patterns of the involved cells. To simultaneously assess the transcriptomes of both organisms during their interaction we developed dual 3'Seq, a tag-based sequencing protocol that allows for exact quantification of differentially expressed transcripts in interacting pro-and eukaryotic cells without prior fixation or physical disruption of the interaction.
Results:
Human epithelial cells were infected with Salmonella enterica Typhimurium as a model system for invasion of the intestinal epithelium, and the transcriptional response of the infected host cells together with the differential expression of invading and intracellular pathogen cells was determined by dual 3'Seq coupled with the next-generation sequencing-based transcriptome profiling technique deepSuperSAGE (deep Serial Analysis of Gene Expression). Annotation to reference transcriptomes comprising the operon structure of the employed S. enterica Typhimurium strain allowed for in silico separation of the interacting cells including quantification of polycistronic RNAs. Eighty-nine percent of the known loci are found to be transcribed in prokaryotic cells prior or subsequent to infection of the host, while 75% of all protein-coding loci are represented in the polyadenylated transcriptomes of human host cells.
Conclusions:
Dual 3'Seq was alternatively coupled to MACE (Massive Analysis of cDNA ends) to assess the advantages and drawbacks of a library preparation procedure that allows for sequencing of longer fragments. Additionally, the identified expression patterns of both organisms were validated by qRT-PCR using three independent biological replicates, which confirmed that RELB along with NFKB1 and NFKB2 are involved in the initial immune response of epithelial cells after infection with S. enterica Typhimurium.
Spatially restricting cAMP production to discrete subcellular locations permits selective regulation of specific functional responses. But exactly where and how cAMP signaling is confined is not fully understood. Different receptors and adenylyl cyclase isoforms responsible for cAMP production are not uniformly distributed between lipid raft and non-lipid raft domains of the plasma membrane. We sought to determine the role that these membrane domains play in organizing cAMP responses in HEK293 cells. The freely diffusible FRET-based biosensor Epac2-camps was used to measure global cAMP responses, while versions of the probe targeted to lipid raft (Epac2-MyrPalm) and non-raft (Epac2-CAAX) domains were used to monitor local cAMP production near the plasma membrane. Disruption of lipid rafts by cholesterol depletion selectively altered cAMP responses produced by raft-associated receptors. The results indicate that receptors associated with lipid raft as well as non-lipid raft domains can contribute to global cAMP responses. In addition, basal cAMP activity was found to be significantly higher in non-raft domains. This was supported by the fact that pharmacologic inhibition of adenylyl cyclase activity reduced basal cAMP activity detected by Epac2-CAAX but not Epac2-MyrPalm or Epac2-camps. Responses detected by Epac2-CAAX were also more sensitive to direct stimulation of adenylyl cyclase activity, but less sensitive to inhibition of phosphodiesterase activity. Quantitative modeling was used to demonstrate that differences in adenylyl cyclase and phosphodiesterase activities are necessary but not sufficient to explain compartmentation of cAMP associated with different microdomains of the plasma membrane.
Malaria still persists as one of the deadliest infectious disease in addition to AIDS and tuberculosis. lt is a leading cause of high mortality and morbidity rates in the developing world despite of groundbreaking research on global eradication of the disease initiated by WHO, about half a century ago. Lack of a commercially available vaccine and rapid spread of drug resistance have hampered the attempts of extinguishing malaria, which still leads to an annual death toll of about one million people. Resistance to anti-malarial compounds thus renders search for new target proteins imperative. The kinome of the human malaria parasite Plasmodium falciparum comprises representatives of most eukaryotic protein kinase groups, including kinases which regulate proliferation and differentiation processes. Several reports till date have suggested involvement of parasite kinases in the human host and as well as in the mosquito vector. Kinases essential for life cycle stages of the parasite represent promising targets for anti-malarial compounds thus, provoking characterization of additional malarial kinases. Despite extensive research on most plasmodial enzymes, very little information is available regarding the four identified members of the cyclin dependent kinase like kinase (CLK) family. Thus, the present thesis dealt with the functional characterization of four members of the PfCLK kinase family of the parasite denoted as PfCLK-1/Lammer, PfCLK-2, PfCLK-3 and PfCLK-4 with a special focus on the first two kinases. Additionally, one Ca2+/Calmodulin dependent putative kinase-related protein, PfPKRP, presumed to be involved in sexual stage development of the parasite, was investigated for its expression in the life cycle of the parasite. In other eukaryotes, CLK kinases regulate mRNA splicing through phosphorylation of Serine/Arginine-rich proteins. Transcription analysis revealed abundance of PfCLK kinase genes throughout the asexual blood stages and in gametocytes. By reverse genetics approach it was demonstrated that all four kinases are essential for completion of the asexual replication cycle of P. falciparum. PfCLK 1/Lammer possesses two nuclear localization signals and PfCLK-2 possesses one of these signals upstream of the C-terminal catalytic domains. Protein level expression and sub-cellular localization of the two kinases was determined by generation of antiserum directed against the kinase domains of the respective kinase. Indirect immunofluorescence, Western blot and electron microscopy data confirm that the kinases are primarily localized in the parasite nucleus, and in vitro assays show that both enzymes are associated with phosphorylation activity. Finally, mass spectrometric analysis of co immunoprecipitated proteins shows interactions of the two PfCLK kinases with proteins, which have putative nuclease, phosphatase or helicase functions. PfPKRP on the other hand is predominantly expressed during gametocyte differentiation as identified from transcriptional analysis. Antiserum directed against the catalytic domain of PfPKRP detected the protein expression profile in both asexual and gametocyte parasite lysates. Via immunofluorescence assay, the kinase was localized in the parasite cytoplasm in a punctuated manner, mostly in the gametocyte stages. Reverse genetics resulted in the generation of PfPKRP gene-disruptant parasites, thus demonstrating that unlike CLK kinases, PfPKRP is dispensable for asexual parasite survival and hence might have crucial role in sexual development of the parasite. On one hand, characterization of PfCLK kinases exemplified the kinases involved in parasite replication cycle. Successful gene-disruption and protein expression of PfPKRP kinase on the other hand, demonstrated a role of the kinase in sexual stage development of the parasite. Both kinase families therefore, represent potential candidates for anti-plasmodial compounds.
Streptococcus pneumoniae (pneumococci) are Gram-positive bacteria and commensals of the nasopharyngeal cavity. Besides colonization, pneumococci are responsible for severe local infections such as otitis media, sinusitis and life-threatening invasive diseases, including pneumonia, sepsis and meningitis. The surface of pneumococci is decorated with proteins that are covalently or non-covalently anchored to the cell wall. The most unique group of cell wall associated proteins in pneumococci are the choline-binding proteins (CBPs). PspC, also known as SpsA or CbpA, is a multifunctional choline-binding protein that plays an essential role in pneumococcal pathogenesis by functioning as an adhesin. PspC promotes adherence of pneumococci to mucosal epithelial cells by interacting in a human specific manner with the free secretory component (SC) or to SC as part of the secretory IgA (SIgA) or polymeric immunoglobulin receptor (pIgR). PspC also interacts specifically with the soluble complement Factor H. Apparently, PspC uses two different epitopes for binding the soluble host protein Factor H and SC of pIgR. However, the mechanism by which these independent interactions facilitate pneumococcal infections under physiological and host specific conditions have not yet been completely elucidated. This study aims to explore the impact of the PspC interaction with human pIgR (hpIgR) or complement regulator Factor H on pneumococcal virulence. Here the cellular and molecular basis of PspC-mediated adherence to and invasion of host epithelial and endothelial cells was demonstrated. The genetic approach, specific pharmacological inhibitors and immunoblot analysis demonstrated the complexity of the induced signal transduction pathways during PspC-hpIgR mediated pneumococcal uptake by host cells. Inhibition studies with specific inhibitors of actin cytoskeleton and microtubules demonstrated that the dynamics of host cell cytoskeleton are essential for pneumococcal uptake by mucosal epithelial cells. Moreover, this study reports for the first time that the small GTPase Cdc42 is essential for pneumococcal internalization into epithelial cells via the PspC-hpIgR mechanism. In addition, in infection experiments performed in presence of specific inhibitors of PI3-kinase/Akt and protein tyrosine kinase (PTKs), hpIgR-mediated pneumococcal uptake by host cells was significantly blocked. Amongst PTKs the Src kinase pathway, ERK1/2 and JNK pathways were implicated during pneumococcal ingestion by hpIgR expressing cells. In addition, inhibition experiments performed in the presence of individual inhibitors or with a combination of inhibitors suggested the independent activation of PI3-kinase/Akt and Src kinase pathways during pneumococcal infections of hpIgR expressing cells. By employing specific inhibitors and siRNA in cell culture infection experiments it was further demonstrated that pneumococcal endocytosis by host epithelial cells via the PspC-hpIgR mechanism depends on clathrin and dynamin. PspC recruits also Factor H to the pneumococcal cell surface. Consequently, the impact of pneumococcal cell surface bound Factor H on adherence to host cells and the molecular mechanism facilitating the uptake of Factor H bound pneumococci by epithelial cells was investigated. Flow cytometry and immunoblots revealed that S. pneumoniae has evolved the ability to recruit both purified Factor H as well as Factor H from human plasma or serum. Moreover, it was demonstrated that the recruitment of Factor H is independent of the PspC-subtypes and that capsular polysaccharide (CPS) interferes with its recruitment. Factor H bound to pneumococci significantly increased bacterial attachment to and invasion of host epithelial cells including nasopharyngeal cells (Detroit562), lung epithelial cells (A549), and human brain-derived endothelial cells (HBMEC). Blocking experiments demonstrated that bacteria bound Factor H interacts via the heparin binding sites on Factor H with eukaryotic cell surface glycosaminoglycans and that this interaction promotes pneumococcal adherence to host cells. In addition, inhibition studies with mAbs recognizing specifically different short consensus repeats (SCR) of Factor H suggested that SCR 19-20 of Factor H are essential for the pneumococcal interaction with host epithelial cells via Factor H. In the presence of Factor H, attachment of pneumococci to human polymorphonuclear leukocytes (PMNs) is enhanced. The integrin CD11b/CD18 was identified as the cellular receptor on PMNs. By using pharmacological inhibitors the impact of host cell cytoskeleton and signalling molecules, such as PTKs and PI3-kinase, for Factor H-mediated pneumococcal internalization into eukaryotic cells was shown. Taken together, the results revealed that Factor-H mediated pneumococcal infection requires a concerted role of host epithelial cell surface glycosaminoglycans, integrins and host cell signalling pathways.
Insights;
(2023)
The cluster of texts assembled here were imagined, crafted, and brought together as a collaborative writing project that emerged from the seminar titled "Words Matter Worlds: Activist Scholarship and Literary Praxis," which convened over the course of the 2021/22 winter semester as an offering of the American Studies department of the Julius-Maximilians-Universität Würzburg. Like the seminar that nurtured the considerations that evolve here, these contributions engage with how scholarly writing practices in general, and literary and cultural studies in particular, can remake the world.
A liquid chromatography tandem mass spectrometry method for the analysis of ten kinase inhibitors (afatinib, axitinib, bosutinib,cabozantinib, dabrafenib, lenvatinib, nilotinib, osimertinib, ruxolitinib, and trametinib) in human serum and plasma for theapplication in daily clinical routine has been developed and validated according to the US Food and Drug Administration andEuropean Medicines Agency validation guidelines for bioanalytical methods. After protein precipitation of plasma samples withacetonitrile, chromatographic separation was performed at ambient temperature using a Waters XBridge® Phenyl 3.5μm(2.1×50 mm) column. The mobile phases consisted of water-methanol (9:1, v/v) with 10 mM ammonium bicarbonate as phase A andmethanol-water (9:1, v/v) with 10 mM ammonium bicarbonate as phase B. Gradient elution was applied at a flow rate of 400μL/min. Analytes were detected and quantified using multiple reaction monitoring in electrospray ionization positive mode. Stableisotopically labeled compounds of each kinase inhibitor were used as internal standards. The acquisition time was 7.0 min perrun. All analytes and internal standards eluted within 3.0 min. The calibration curves were linear over the range of 2–500 ng/mLfor afatinib, axitinib, bosutinib, lenvatinib, ruxolitinib, and trametinib, and 6–1500 ng/mL for cabozantinib, dabrafenib, nilotinib,and osimertinib (coefficients of correlation≥0.99). Validation assays for accuracy and precision, matrix effect, recovery,carryover, and stability were appropriate according to regulatory agencies. The rapid and sensitive assay ensures high throughputand was successfully applied to monitor concentrations of kinase inhibitors in patients.
G protein-coupled receptor research looks out for new technologies to elucidate the complex
processes of receptor activation, function and downstream signaling with spatiotemporal
resolution, preferably in living cells and organisms. A thriving approach consists in making use
of the unsurpassed properties of light, including its high precision in space and time, noninvasiveness
and high degree of orthogonality regarding biological processes. This is realized
by the incorporation of molecular photoswitches, which are able to effectively respond to light,
such as azobenzene, into the structure of a ligand of a given receptor. The muscarinic
acetylcholine receptors belong to class A GPCRs and have received special attention in this
regard due to their role as a prototypic pharmacological system and their therapeutic potential.
They mediate the excitatory and inhibitory effects of the neurotransmitter acetylcholine and
thus regulate diverse important biological processes, especially many neurological functions in
our brain.
In this work, the application of photopharmacological tool compounds to muscarinic receptors
is presented, consisting of pharmacophores extended with azobenzene as light-responsive
motif. Making use of the dualsteric concept, such photochromic ligands can be designed to bind
concomitantly to the orthosteric and allosteric binding site of the receptor, which is
demonstrated for BQCAAI (M1) and PAI (M2) and may lead to subtype- and functionalselective
photoswitchable ligands, suitable for further ex vivo and in vivo studies.
Moreover, photoswitchable ligands based on the synthetic agonist iperoxo were investigated
extensively with regard to their photochemical behavior and pharmacological profile, outlining
the advantages and challenges of using red-shifted molecular photoswitches, such as tetraortho-
fluoro azobenzene. For the first time on a GPCR it was examined, which impact the
different substitution pattern has on both the binding and the activity on the M1 receptor. Results
show that substituted azobenzenes in photopharmacological compounds (F4-photoiperoxo and
F4-iper-azo-iper) not just represent analogs with other photophysical properties but can exhibit
a considerably different biological profile that has to be investigated carefully.
The achievements gained in this study can give important new insights into the binding mode
and time course of activation processes, enabling precise spatial and temporal resolution of the
complex signaling pathway of muscarinic receptors. Due to their role as exemplary model
system, these findings may be useful for the investigation into other therapeutically relevant
GPCRs.
Background: During early stages of brain development, secreted molecules, components of intracellular signaling pathways and transcriptional regulators act in positive and negative feed-back or feed-forward loops at the mid-hindbrain boundary. These genetic interactions are of central importance for the specification and subsequent development of the adjacent mid-and hindbrain. Much less, however, is known about the regulatory relationship and functional interaction of molecules that are expressed in the tectal anlage after tectal fate specification has taken place and tectal development has commenced.
Results: Here, we provide experimental evidence for reciprocal regulation and subsequent cooperation of the paired-type transcription factors Pax3, Pax7 and the TALE-homeodomain protein Meis2 in the tectal anlage. Using in ovo electroporation of the mesencephalic vesicle of chick embryos we show that (i) Pax3 and Pax7 mutually regulate each other's expression in the mesencephalic vesicle, (ii) Meis2 acts downstream of Pax3/7 and requires balanced expression levels of both proteins, and (iii) Meis2 physically interacts with Pax3 and Pax7. These results extend our previous observation that Meis2 cooperates with Otx2 in tectal development to include Pax3 and Pax7 as Meis2 interacting proteins in the tectal anlage.
Conclusion: The results described here suggest a model in which interdependent regulatory loops involving Pax3 and Pax7 in the dorsal mesencephalic vesicle modulate Meis2 expression. Physical interaction with Meis2 may then confer tectal specificity to a wide range of otherwise broadly expressed transcriptional regulators, including Otx2, Pax3 and Pax7.
Barley stripe mosaic virus (BSMV) RNA which was previously reported to contain poly(A) sequences (Agranovsky et al., 1978) can be specifically esterified with tyrosine in vitro in the presence of an aminoacyl-tRNA synthetase fraction from wheat embryos. All the three RNA components of the BSMV strain with a three-component genome (Norwich) and both RNA components of a two-component strain (Russian) can be tyrosylated. The poly(A)-containing (bound to oligo(dT)-cellulose) and poly(A)-deficient(not bound to oligo(dT)-cellulose) fractions of BSMV RNA display a similar amino acidaccepting ability. The nucleotide sequence which accepts tyrosine is coupled with the intact genomic polyadenylated BSMV RNA. The viral RNA isolated after sucrose density gradient centrifugation under drastic denaturing conditions retains its aminoacylating activity, which suggests that this activity is not due to the presence in a BSMV RNA preparation of a tyrosine tRNA associated with BSMV RNA. Inhibition of aminoacylation of the 3’-oxidized (treated with sodium metaperiodate) BSMV RNA suggests that the tyrosine-accepting structure is localized at the 3’ terminus of BSMV RNA molecules. It is shown that segments of different lengths obtained upon random fragmentation can be tyrosylated. The 3’-terminal (tyrosine-accepting) poly(A)+ segments can be isolated. The shortest segments of viral RNA capable of being aminoacylated [i.e., containing both tRNA-like structure and poly(A)] consists of approximately 150-200 nucleotides. The analysis of the oligonucleotides derived from individual BSMV RNA components labeled with 32P at the 3’ end revealed two types of 3’-terminal sequences different from poly(A). It is suggested that a poly(A) sequence is intercalated between a 3’-terminal tyrosineaccepting structure and the 5’-terminal portion of poly(A)+ BSMV RNA.
Expression of human foamy virus is differentially regulated during development in transgenic mice
(1992)
Tbe human foamy virus (HFV) is a recently characterized member ofthe spumavirus family. Although no diseases have been unequivocally associated with HFV infection, expression of HFV regulatory genes in transgenie mice induces a characteristic aeute neuro degenerative disease and a myopathy. To better eharaeterize the sequenee of events leading to disease, and to gain a better understanding of the underlying pathogenetic meehanisms, we have analyzed in detail the transgene expression pattern during development. Transcription of a construet containing all regulatory elements and aneillary genes of mv was analyzed by in situ hybridization and was shown to occur in two distinct phases. At midgestation, low but widespread expression was first deteeted in eells of extraembryonie tissues. Later, various tissues originating from embryonie mesoderm, neuroeetoderm, and neural erest transeribed the transgene at moderate levels. However, expression deereased dramatically during late gestation and was suppressed shortly after birth. After a latency period of up to 5 weeks, transeription of the transgene resumed in single eelJs distributed irregularly in the central nervous system and in the skeletal museIe. By the age of 8 weeks, an increasing number of eells displayed much higher expression levels than in embryonie Iife and eventually underwent severe degenerative ehanges. These findings demonstrate that HFV transgene expression is differentially regulated in development and that HFV cytotoxicity may be dose-dependent. Such biphasic pattern of expression differs from that of murine retroviruses and may be explained by the specificity of HFV regulatory elements in combination with cellular faetors. Future studies of this model system should, therefore, provide novel insights in the mechanisms controlling retrovirallatency.
Humanfoamy virus (HFV) is a retrovirus encoding structural genes and, like human immunodeficiency virus and human T ceU leukemia virus I, several anciUary reading frames collectively termed the belgenes. We have previously shown that HFV transgenic mice develop an encephalopathy with neuronal loss in hippocampus and cerebral cortex. We have now raised and characterized rabbit antisera to various recombinant portions of gag, pot, env, and bel-I, the viraltransactivator. Immunoreactivity for gag and bel-I was observed in nuclei and processes of hippocampal and cortical neurons before the onset of morphological lesions and correlated with the appearance of HFV mRNA. Astrocyte-derived multinucleated giant ceUs containing HFV proteins were present in the brain oftransgenic mice coexpressingfuU- length HFV genes but not in mice expressing truncated gag and env, suggesting that these genes contain afusogenic domain. Expression of fuU-length structural genes decreased the life expectancy oftransgenic mice, implying an a4Juvant rolefor these proteins in HFV-induced brain damage. (Am] Pathol 1993, 142:1061-1072)
Imprinted genes play important roles in brain development. As the neural developmental capabilities of human parthenogenetic embryonic stem cells (hpESCs) with only a maternal genome were not assessed in great detail, hence here the potential of hpESCs to differentiate into various neural subtypes was determined. In addition DNA methylation and expression of imprinted genes upon neural differentiation was also investigated. The results demonstrated that hpESC-derived neural stem cells (hpNSCs) showed expression of NSC markers Sox1, Nestin, Pax6, and Musashi1 (MS1), the silencing of pluripotency genes (Oct4, Nanog) and the absence of activation of neural crest (Snai2, FoxD3) and mesodermal (Acta1) markers. Moreover, confocal images of hpNSC cultures exhibited ubiquitous expression of NSC markers Nestin, Sox1, Sox2 and Vimentin. Differentiating hpNSCs for 28 days generated neural subtypes with neural cell type-specific morphology and expression of neuronal and glial markers, including Tuj1, NeuN, Map2, GFAP, O4, Tau, Synapsin1 and GABA. hpNSCs also responded to region-specific differentiation signals and differentiated into regional phenotypes such as midbrain dopaminergic- and motoneuron-type cells. hpESC-derived neurons showed typical neuronal Na+/K+ currents in voltage clamp mode, elicited multiple action potentials with a maximum frequency of 30 Hz. Cell depicted a typical neuron-like current pattern that responded to selective pharmacological blockers of sodium (tetrodotoxin) and potassium (tetraethylammonium) channels. Furthermore, in hpESCs and hpNSCs the majority of CpGs of the differentially methylated regions (DMRs) KvDMR1 were methylated whereas DMR1 (H19/Igf2 locus) showed partial or complete absence of CpG methylation, which is consistent with a parthenogenetic (PG) origin. Upon differentiation parent-of-origin-specific gene expression was maintained in hpESCs and hpNSCs as demonstrated by imprinted gene expression analyses. Together this shows that despite the lack of a paternal genome, hpNSCs are proficient in differentiating into glial- and neuron-type cells, which exhibit electrical activity similar to newly formed neurons. Moreover, maternal-specific gene expression and imprinting-specific DNA-methylation are largely maintained upon neural differentiation. hpESCs are a means to generate histocompatible and disease allele-free ESCs. Additionally, hpESCs are a unique model to study the influence of imprinting on neurogenesis.
Parent of origin imprints on the genome have been implicated in the regulation of neural cell type differentiation. The ability of human parthenogenetic (PG) embryonic stem cells (hpESCs) to undergo neural lineage and cell type-specific differentiation is undefined. We determined the potential of hpESCs to differentiate into various neural subtypes. Concurrently, we examined DNA methylation and expression status of imprinted genes. Under culture conditions promoting neural differentiation, hpESC-derived neural stem cells (hpNSCs) gave rise to glia and neuron-like cells that expressed subtype-specific markers and generated action potentials. Analysis of imprinting in hpESCs and in hpNSCs revealed that maternal-specific gene expression patterns and imprinting marks were generally maintained in PG cells upon differentiation. Our results demonstrate that despite the lack of a paternal genome, hpESCs generate proliferating NSCs that are capable of differentiation into physiologically functional neuron-like cells and maintain allele-specific expression of imprinted genes. Thus, hpESCs can serve as a model to study the role of maternal and paternal genomes in neural development and to better understand imprinting-associated brain diseases.