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No abstract available
Neoplasia in Xiphophorus can be classified into a) a large group that is triggered by carcinogens; b) a large group triggered by promoters; c) a small group that develops "spontaneously" following interpopulational and interracial hybridizations; and d) a small group that develops "spontaneously" following germ line mutation. The process leading to susceptibility for neoplasia is represented by the disintegration of gene systems that normally protect the fish from neoplasia. Hybridization is the most effective process that leads to disintegration of the protection gene systems. Environmental factors may complete disintegration and thus may trigger neoplasia. It is discussed whether the findings on Xiphophorus may also apply to humans.
Neoplasia in Xiphophorus can be classified into: a) a Jarge group triggered by carcinogens; b) a large group triggered by promoters; and c) a small group that develops "spontaneously" according to Mendelian Jaw. The process leading to susceptibility for neoplasia is represented by the disintegration of gene systems that normally protect the fish from neoplasia. Interpopulational arid interracial hybridization is the most effective process that Ieads to disintegration of the protective gene systems. Environmental factors may complete disintegration in somatic cells and thus may trigger neoplasia. The applications of the findings on Xiphophorus to humans are discussed.
No abstract available
Dargestellt werden die theoretischen Ziele, das methodische Vorgehen und die ersten Ergebnisse einer Longitudinalstudie zur Genese individueller Kompetenzen (LOGIK) im Vorschulalter. Dabei geht es vor allem um generelle Merkmale und differentielle Verläufe bei der Entwicklung kognitiver, sozialer und motivationaler Kompetenzen.
No abstract available
Zhao Ji (1082-1135), better known as Emperor Huizong (r. 1100-1126) of the Southern Song Dynasty (960-1127) gained a reputation as supreme perfectionist as artist, art collector and connoisseur, a ruler devoted to the faith of Daoism, squandering a fortune on building palaces and halls and on landscape gardening. A famous example of his costly ‘folie de grandeur’ is the Sacred Northeast Mountain Peak Genyue, a gigantic rock garden in the northeast part of the Old City of the capital Kaifeng. The garden is described in sources such as the Huayanggong jishi (Description of the Florescent Solitary Palace) by the Buddhist monk Zu Xiu from 1127 and Zhang Hao’s (ca. 1180-1250) Genyue ji (Record of the Northeast Marchmount). The project in search of auspicious blessing started in 1118, having originated in the emperor’s conviction that the Daoist Immortals would descend to this exquisite paradise situated in the centre of the world, his capital. In his conviction the landscape garden that exceeded nature’s beauty would prolong and glorify his rule for ten thousand years. The Genyue was completed in January 1123, and thus became part of Emperor Huizong’s Divine Empyrean Daoist ideology of statecraft. Contrary to all auspicious symbolism, the Song’s emblematic demonstrations of power, and the necessity to meet political expectations, Emperor Huizong proved incapable of finding a solution to the disastrous situation at the northern frontier with Jin troupes moving onto his capital. Completed in 1123 the Genyue Marchmount was destroyed in the cold winter of 1126/1127 by the inhabitants of Kaifeng in their desperate struggle for survival in their besieged town.
No abstract available
No abstract available
For the EU “effective multilateralism” in, with and within international organisations is the foundation of a system of global governance, so is laid down in the ESS. Therefore the term is used to label the EU’s activities in the UN-family and to characterise the relations with the UN in the wider context of global governance. It is the political argument for the EU’s commitment in military crisis management, side by side with UN peacekeepers. The UN in turn speaks of multilateralism to call for the EU’s loyalty and partnership. Both organisations build their partnership on the common normative ground of multilateralism. The paper questions these rhetorical denominations critically. It goes beyond the political declarations to analyse the degree and quality of “effective multilateralism” in reality in and with international organisations, using the example of UN-EU-relations in military crisis management. The theoretical approach of multilateralism serves as the starting point of the analysis and theoretical basis of the paper (Chapter 1). The special EU-touch in “effective multilateralism” in comparison to the “UN-touch” is subject of Chapter 2. This analysis is necessary due to the meanwhile inflationary use of the term “effective multilateralism” in almost every CSFP context. Are the institutional steps to a partnership in crisis management as well as the operational collaboration in DR Congo (2003/2006/2009) and Chad/CAR (2008/2009) in line with “multilateralism”? is the question that is answered in the paper (Chapter 3).
No abstract available
Es wird argumentiert, daß bei der Prüfung der Homgenität von Zentren in mehrfaktoriellen Multicenter-Studien vor allem entscheidend ist, daß sich die Zentren in den faktoriellen Variablen nicht unterscheiden, deren Effekte in der späteren Auswertung interpretiert werden sollen. Dazu wird folgendes Procedere vorgeschlagen: (1) überprüfe, ob in allen Zentren die Randomisierungsbedingungen eingehalten wurden, (2) überprüfe, ob die Zentren homogen bezogen auf die eingebrachten Schichtvariablen (z.B. Geschlecht, Indikation) sind und (3) überprüfe, ob die Zentren homogen sind bezogen auf die Wechselwirkungen zwischen den eingebrachten faktoriellen Variablen. Es wird gezeigt, daß vor allem Forderung (3) für die Interpretationsfähigkeit der Ergebnisse von entscheidender Bedeutung ist. Möglichkeiten der statistischen Prüfung dieser Voraussetzungen werden an einem Beispiel aus der klinischen Prüfung eines Psychopharmakons vorgestellt.
Digitalization is one of the global challenges for justice and This volume documents the presentations of a multilingual online conference on "Digitalization as a challenge for justice and administration" held in March 2022. The contributions of the international team of authors provide insights into central issues of this highly relevant subject from African, Japanese, U.S., Swiss, Latin American and German perspectives. The result is a multifaceted picture of digitalization in the context of public, private and even criminal law.