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Antimicrobial stewardship measures in cardiac surgery and its impact on surgical site infections
Please always quote using this URN: urn:nbn:de:bvb:20-opus-265533
- Objective The goal of this study was to monitor the compliance and impact on a protocol change of surgical antimicrobial prophylaxis in cardiac surgery favouring cefazolin instead cefuroxime, initiated by the hospital’s antimicrobial stewardship team. Methods This quality improvement study was performed in a tertiary care hospital in collaboration with the department of cardiothoracic surgery and the hospitals antimicrobial stewardship team following a revision of the standard for surgical antimicrobial prophylaxis including 1029 patientsObjective The goal of this study was to monitor the compliance and impact on a protocol change of surgical antimicrobial prophylaxis in cardiac surgery favouring cefazolin instead cefuroxime, initiated by the hospital’s antimicrobial stewardship team. Methods This quality improvement study was performed in a tertiary care hospital in collaboration with the department of cardiothoracic surgery and the hospitals antimicrobial stewardship team following a revision of the standard for surgical antimicrobial prophylaxis including 1029 patients who underwent cardiac surgery. 582 patients receiving cefuroxime and 447 patients receiving cefazolin respectively were compared without altering any other preventative perioperative measures including its postoperative duration of less than 24 h. Adherence and surgical site infections were compiled and analysed. Results A complete adherence was achieved. Overall surgical site infections occurred in 37 (3.6%) of the cases, 20 (3.4%) in cefuroxime patients and 17 (3.8%) in cefazolin patients (p value = 0.754). No statistically significant differences could be found in any of the primary endpoints, but there was a trend towards less deep sternal wound infections in the cefazolin group. Conclusions The study supports the role of antimicrobial stewardship in cardiac surgery and mirrors the success of a multidisciplinary team aiming to minimize adverse events by optimizing antibiotic use.…
Author: | Güzin Surat, Dominik Bernsen, Christoph Schimmer |
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URN: | urn:nbn:de:bvb:20-opus-265533 |
Document Type: | Journal article |
Faculties: | Medizinische Fakultät |
Medizinische Fakultät / Klinik und Poliklinik für Thorax-, Herz- u. Thorakale Gefäßchirurgie | |
Language: | English |
Parent Title (English): | Journal of Cardiothoracic Surgery |
Year of Completion: | 2021 |
Volume: | 16 |
Article Number: | 309 |
Source: | Journal of Cardiothoracic Surgery (2021) 16:309, https://doi.org/10.1186/s13019-021-01693-7 |
DOI: | https://doi.org/10.1186/s13019-021-01693-7 |
Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 617 Chirurgie und verwandte medizinische Fachrichtungen |
Tag: | antimicrobial stewardship; cardiac surgery; surgical antimicrobial prophylaxis; surgical site infections |
Release Date: | 2022/04/29 |
Open-Access-Publikationsfonds / Förderzeitraum 2021 | |
Licence (German): | CC BY: Creative-Commons-Lizenz: Namensnennung 4.0 International |