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The septal bulge - an early echocardiographic sign in hypertensive heart disease

Zitieren Sie bitte immer diese URN: urn:nbn:de:bvb:20-opus-191433
  • Patients in the early stage of hypertensive heart disease tend to have normal echocardiographic findings. The aim of this study was to investigate whether pathology-specific echocardiographic morphologic and functional parameters can help to detect subclinical hypertensive heart disease. One hundred ten consecutive patients without a history and medication for arterial hypertension (AH) or other cardiac diseases were enrolled. Standard echocardiography and two-dimensional speckle tracking -imaging analysis were performed. Resting blood pressurePatients in the early stage of hypertensive heart disease tend to have normal echocardiographic findings. The aim of this study was to investigate whether pathology-specific echocardiographic morphologic and functional parameters can help to detect subclinical hypertensive heart disease. One hundred ten consecutive patients without a history and medication for arterial hypertension (AH) or other cardiac diseases were enrolled. Standard echocardiography and two-dimensional speckle tracking -imaging analysis were performed. Resting blood pressure (BP) measurement, cycle ergometer test (CET), and 24-hour ambulatory BP monitoring (ABPM) were conducted. Patients were referred to "septal bulge (SB)" group (basal-septal wall thickness >= 2 mm thicker than mid-septal wall thickness) or "no-SB" group. Echocardiographic SB was found in 48 (43.6%) of 110 patients. In this SB group, 38 (79.2%) patients showed AH either by CET or ABPM. In contrast, in the no-SB group (n = 62), 59 (95.2%) patients had no positive test for AH by CET or ABPM. When AH was solely defined by resting BP, SB was a reasonable predictive sign for AH (sensitivity 73%, specificity 76%). However, when AH was confirmed by CET or ABPM the echocardiographic SB strongly predicted clinical AH (sensitivity 93%, specificity 86%). In addition, regional myocardial deformation of the basal-septum in SB group was significantly lower than in no-SB group (14 +/- 4% vs. 17 +/- 4%; P < .001). In conclusion, SB is a morphologic echocardiographic sign for early hypertensive heart disease. Sophisticated BP evaluation including resting BP, ABPM, and CET should be performed in all patients with an accidental finding of a SB in echocardiography.zeige mehrzeige weniger

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Autor(en): Philipp Daniel Gaudron, Dan Liu, Friederike Scholz, Kai Hu, Christiane Florescu, Sebastian Herrmann, Bart Bijnens, Georg Ertl, Stefan Störk, Frank Weidemann
URN:urn:nbn:de:bvb:20-opus-191433
Dokumentart:Artikel / Aufsatz in einer Zeitschrift
Institute der Universität:Medizinische Fakultät / Medizinische Klinik und Poliklinik I
Medizinische Fakultät / Deutsches Zentrum für Herzinsuffizienz (DZHI)
Sprache der Veröffentlichung:Englisch
Titel des übergeordneten Werkes / der Zeitschrift (Englisch):Journal of the American Society of Hypertension
Erscheinungsjahr:2016
Band / Jahrgang:10
Heft / Ausgabe:1
Seitenangabe:70-80
Originalveröffentlichung / Quelle:Journal of the American Society of Hypertension (2016) 10:1, S. 70-80. https://doi.org/10.1016/j.jash.2015.11.006
DOI:https://doi.org/10.1016/j.jash.2015.11.006
Allgemeine fachliche Zuordnung (DDC-Klassifikation):6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Freie Schlagwort(e):Septal bulge; blood pressure monitoring; echocardiography; heart disease; hypertension
Datum der Freischaltung:26.02.2021
Lizenz (Deutsch):License LogoCC BY-NC-ND: Creative-Commons-Lizenz: Namensnennung, Nicht kommerziell, Keine Bearbeitungen 4.0 International