Refine
Has Fulltext
- yes (506)
Is part of the Bibliography
- yes (506)
Year of publication
- 2012 (506) (remove)
Document Type
- Journal article (364)
- Doctoral Thesis (133)
- Preprint (3)
- Review (3)
- Book (1)
- Conference Proceeding (1)
- Report (1)
Language
- English (506) (remove)
Keywords
- Medizin (42)
- hadron-hadron scattering (15)
- Biologie (13)
- Psychologie (12)
- systematic uncertainty (9)
- cancer (8)
- gene expression (8)
- melanoma (8)
- expression (7)
- jet energy scale (7)
- protein (7)
- brain (6)
- differentiation (6)
- in vitro (6)
- ATLAS (5)
- Apoptosis (5)
- Chemie (5)
- Maus (5)
- apoptosis (5)
- binding (5)
- genome-wide association (5)
- mice (5)
- therapy (5)
- transverse momentum (5)
- Atlas detector (4)
- Drosophila (4)
- HIV (4)
- Melanom (4)
- Taufliege (4)
- Vaccinia-Virus (4)
- cells (4)
- disease (4)
- emotion (4)
- gene (4)
- genetics (4)
- identification (4)
- inhibitor (4)
- jet energy resolution (4)
- lung cancer (4)
- messenger RNA (4)
- metaanalysis (4)
- model (4)
- neuroprotection (4)
- oncolytic virotherapy (4)
- receptor (4)
- resistance (4)
- signal transduction (4)
- single-crystal X-ray study (4)
- survival (4)
- tumors (4)
- vaccinia virus (4)
- validation (4)
- Dendritische Zelle (3)
- Evolution (3)
- Fuchsbandwurm (3)
- Genexpression (3)
- Knockout <Molekulargenetik> (3)
- Lungenkrebs (3)
- MC simulation (3)
- MRI (3)
- Modellierung (3)
- Myc (3)
- Perylenderivate (3)
- Pneumolysin (3)
- SM background (3)
- T cells (3)
- Zelldifferenzierung (3)
- association (3)
- breast-tumors (3)
- central-nervous-system (3)
- children (3)
- classification (3)
- colony-stimulating factor (3)
- combination therapy (3)
- epithelial cells (3)
- escherichia coli (3)
- genes (3)
- jet energy scale uncertainty (3)
- light quark jet (3)
- lung (3)
- magnetic resonance imaging (3)
- malaria (3)
- multijet background (3)
- multiple sclerosis (3)
- non-prompt lepton (3)
- onkolytische Virotherapie (3)
- oxidative stress (3)
- progression (3)
- quality of life (3)
- serum (3)
- stem cells (3)
- stroke (3)
- top quark mass (3)
- top quark pair (3)
- trial (3)
- ubiquitin (3)
- 5-HT1A (2)
- 5-HT2C (2)
- ADHD (2)
- Alzheimers disease (2)
- Anti-k Jet (2)
- Apoptose (2)
- Arzneimitteldesign (2)
- Ausbreitung (2)
- BDNF (2)
- Bakteriengift (2)
- Biochemie (2)
- Cl Lowe limit (2)
- DNA repair (2)
- Datenbank (2)
- Dendritic cell (2)
- Deutschland (2)
- Diabetes mellitus (2)
- Drugs (2)
- EF-1A (2)
- Echinococcus (2)
- Embryonale Stammzelle (2)
- Extrazelluläre Matrix (2)
- Extremwertstatistik (2)
- FAAH (2)
- Geruchssinn (2)
- Graphen (2)
- Heterostruktur (2)
- Hey (2)
- Higgs (2)
- Hirnhautentzündung (2)
- Image-guidance (2)
- Integrated network analysis (2)
- JES uncertainty (2)
- Keldysh formalism (2)
- Klimaänderung (2)
- LHC (2)
- Landnutzung (2)
- Learning (2)
- Leishmania major (2)
- Lernen (2)
- MAP-Kinase (2)
- MC event generator (2)
- MODIS (2)
- MYC (2)
- Makrophage (2)
- Malaria (2)
- Meningitis (2)
- Metastase (2)
- Modell (2)
- Molekulargenetik (2)
- Monte Carlo (2)
- NPY (2)
- Netzwerkanalyse (2)
- Neurogenese (2)
- New Zealand (2)
- Newton-Verfahren (2)
- Numerisches Verfahren (2)
- Onkolyse (2)
- Optimale Kontrolle (2)
- Optische Spektroskopie (2)
- P300 (2)
- Photoelektronenspektroskopie (2)
- Pore (2)
- Porenbildung (2)
- Pp Collision (2)
- Proliferation (2)
- RNA-seq (2)
- Radiosurgery (2)
- Raf kinases (2)
- Rastertunnelmikroskop (2)
- Renormierungsgruppe (2)
- SMN (2)
- Serotonin (2)
- Simulation (2)
- Sinnesphysiologie (2)
- Spektroskopie (2)
- Strahlentherapie (2)
- Strahlungstransport (2)
- Supraleiter (2)
- Supraleitung (2)
- Systembiologie (2)
- T = 100 K (2)
- T cell (2)
- Thrombozyt (2)
- Toxin (2)
- Transkriptionsfaktor (2)
- West Africa (2)
- Zeitreihenanalyse (2)
- Zeitrichtung (2)
- ablation (2)
- acceptance time efficiency (2)
- acute kidney injury (2)
- adalimumab (2)
- african trypanosomes (2)
- angiogenesis (2)
- anti-k jet (2)
- antirheumatic agents (2)
- architecture (2)
- astrocytes (2)
- basal ganglia (2)
- biomarkers (2)
- blood pressure (2)
- blood-brain barrier (2)
- breast cancer (2)
- c-myc (2)
- calorimeter (2)
- cancer cells (2)
- carcinoma (2)
- cerebral ischemia (2)
- chemotherapy (2)
- ciliary neurotrophic factor (2)
- climate change (2)
- closed head injury (2)
- coagulation (2)
- comparative genomic hybridization (2)
- decision making (2)
- deficient mice (2)
- degeneration (2)
- dementia (2)
- dendritic cells (2)
- dependent protein-kinase (2)
- depression (2)
- disease progression (2)
- dispersal (2)
- diversity (2)
- domain (2)
- dopamine (2)
- down regulation (2)
- drug (2)
- endocannabinoid (2)
- endophenotype (2)
- endothelial cells (2)
- enterica serovar typhimurium (2)
- environment (2)
- evolution (2)
- experimental autoimmune encephalomyelitis (2)
- fake lepton (2)
- films (2)
- focal cerebral-ischemia (2)
- follow up (2)
- follow-up (2)
- functional characterization (2)
- giant ventral hernia (2)
- graphene (2)
- growth (2)
- ideomotor theory (2)
- immunoreactive neurons (2)
- in vivo (2)
- in-vitro (2)
- inflammation (2)
- injury (2)
- insect immunity (2)
- jet channel (2)
- jet reconstruction efficiency (2)
- jet transverse momentum (2)
- kinase (2)
- laparostomy (2)
- lines (2)
- linkage (2)
- living cells (2)
- localization (2)
- magnetic resonance (2)
- malignant melanoma (2)
- mass spectrometry (2)
- mechanisms (2)
- melanogaster (2)
- metastasis (2)
- microenvironment (2)
- microglia (2)
- migration (2)
- multi-jet background (2)
- muon channel (2)
- mutation (2)
- mutations (2)
- myelin (2)
- myocardial infarction (2)
- myocardial-infarction (2)
- neurons (2)
- nude-mice (2)
- olfactory memory (2)
- oncolysis (2)
- open abdomen (2)
- ovarian cancer (2)
- partial decay width (2)
- pathway (2)
- peptide vaccination (2)
- perception (2)
- perspectives (2)
- phosphorylation (2)
- prevalence (2)
- primary vertex (2)
- proteasome (2)
- randomized controlled trial (2)
- recognition (2)
- regression analysis (2)
- resolution (2)
- responses (2)
- rheumatoid arthritis (2)
- ribosomal RNA (2)
- sample (2)
- schizophrenia (2)
- senescence (2)
- signal cross section (2)
- simulated signal event (2)
- single top event (2)
- single top production (2)
- single top quark (2)
- single top quark production (2)
- sleep (2)
- sleep disorders (2)
- smooth muscle cells (2)
- speech perception (2)
- stability (2)
- staphylococcus aureus (2)
- startle reflex (2)
- surface (2)
- susceptibility gene (2)
- synthetic mesh (2)
- tissue (2)
- tissue engineering (2)
- tolerance (2)
- top quark decay (2)
- trabeculectomy (2)
- transcription (2)
- transmission (2)
- traumatic brain injury (2)
- treatment outcome (2)
- triple in situ hybridization (2)
- tumor (2)
- vaccine (2)
- vacuum conditioning (2)
- variability (2)
- variants (2)
- virulence (2)
- visible cross section (2)
- wR factor = 0.068 (2)
- . (1)
- 1/N expansion (1)
- 14.7K (1)
- 19F-MR (1)
- 1ES 1011+496 (1)
- 1ES 2344+514 (1)
- 1p13.3 (1)
- 1q21 (1)
- 2',7'-dichlorofluorescin (1)
- 2,5-diketopiperazines (1)
- 5-HT transporter (1)
- 68Ga-DOTATATE (1)
- 7000 GeV-cms (1)
- 7q11.2 (1)
- A-type lamins (1)
- ACC deaminase (1)
- AGT (1)
- ALK-1 (1)
- ALMT (1)
- ALS (1)
- AMD (1)
- AMP (1)
- AMPK (1)
- ARF (1)
- ATLAS <Teilchendetektor> (1)
- ATLAS detector (1)
- Abl (1)
- Acetylneuraminsäure <N-> (1)
- Actin (1)
- Actin nucleation (1)
- Actin-bindende Proteine (1)
- Activation induced cell death/AICD (1)
- AdS-CFT-Korrespondenz (1)
- AdS/CFT (1)
- Adiabatic Theorem of quantum mechanics (1)
- Advanced snowmelt (1)
- Ag(111) (1)
- Aharonov-Bohm effect (1)
- Aharonov-Bohm-Effekt (1)
- Ako na Uche (1)
- Aktinnukleation (1)
- Alcohol (1)
- Aldehyde (1)
- Alkohol (1)
- Allergie (1)
- Allergy (1)
- Alliances (1)
- Alps (1)
- Altern (1)
- Alternative Conflict Resolutions (1)
- Alveolar Echinococcosis (1)
- Alveoläre Echinokokkose (1)
- Alzheimer Dementia (1)
- Alzheimer's disease (1)
- Alzheimer-Krankheit (1)
- Alzheimer’s disease (1)
- Amazonia (1)
- Ambulantes Assessment (1)
- Ambulatory Assessment (1)
- Ameisen (1)
- Amyloid <beta-> (1)
- Ancistrocladus (1)
- Anergy (1)
- Aneuploidie (1)
- Angeregter Zustand (1)
- Animal Spirits (1)
- Animal models (1)
- Anoikis (1)
- Anthocyane (1)
- Anthrax toxin (1)
- Antibody (1)
- Anticipation (1)
- Antigen CD28 (1)
- Antikörper (1)
- Antimicrobial activity (1)
- Antizipation (1)
- Anämie (1)
- Arabidopsis (1)
- Araneae (1)
- Areal (1)
- Argumentation (1)
- Artverbreitungsmodellierung (1)
- Arzneimittel (1)
- Aspergillus fumigatus (1)
- Aspergillus niger (1)
- Astrozyt (1)
- Atherosclerotic plaque (1)
- Attentional performance (1)
- Aufmerksamkeits-Defizit-Syndrom (1)
- Ausfallsicheres System (1)
- Ausfallsicherheit (1)
- Autoaggressionskrankheit (1)
- AuxRE (1)
- Auxin-regulated transcription (1)
- B cell (1)
- B cells (1)
- B neisseria meningitidis (1)
- B-tagged jet (1)
- BBCH (1)
- BK virus (1)
- BL Lacertae (1)
- BL-Lacertae-Objekt (1)
- BRAF (1)
- BRCA1 (1)
- BRCA1 positive (1)
- BRCA1/2 negative (1)
- BRCA2 positive (1)
- Bacillus anthracis (1)
- Bacillus megaterium (1)
- Bacterial Toxins (1)
- Bacterial meningitis (1)
- Bakterielle Hirnhautentzündung (1)
- Bakterien (1)
- Basin-Hopping (1)
- Bayesian Estimation (1)
- Berry Phase (1)
- Betriebssystem (1)
- Beweistheorie (1)
- Bildgebendes Verfahren (1)
- Biochemistry (1)
- Biodiversität (1)
- Biogenese (1)
- Biokonjugate (1)
- Biolabelling (1)
- Biologische Aktivität (1)
- Biomarker (1)
- Bioorganometallchemie (1)
- Bioorthogonal (1)
- Biotechnologie (1)
- Biotechnologische Industrie (1)
- Biotechnology (1)
- Black lipid bilayer (1)
- Blazar (1)
- Bloch-Siegert (1)
- Blochmannia (1)
- Blumeria graminis (1)
- Blut-Hirn-Schranke (1)
- Blutbildendes Gewebe (1)
- Blutplättchen (1)
- Blutstammzelle (1)
- Bor (1)
- Boracumulen (1)
- Boracumulene (1)
- Boraheterocycles (1)
- Borheterocyclen (1)
- Boron (1)
- Borylene (1)
- Borylene complexes (1)
- Borylenkomplexe (1)
- Botanik (1)
- Bowen’s disease, periungual (1)
- Box-Jenkins-Verfahren (1)
- Box–Jenkins Program (1)
- Brain edema (1)
- Brain ischemia (1)
- Bre (1)
- Bre-knockout (1)
- Brugia Malayi (1)
- Bullous pemphigoid (1)
- Burkholderia (1)
- Burkholderia pseudomallei (1)
- C-13 NMR (1)
- C-MYC (1)
- C-reactive protein (1)
- C57BL/KALWRIJ mouse (1)
- C9orf72 (1)
- CC2 (1)
- CCL2 (MCP-1) (1)
- CD28 antigen (1)
- CD28-Superagonist (1)
- CD28-superagonist (1)
- CD30 (1)
- CD4(+) (1)
- CD4(+) T-cells (1)
- CD95 (1)
- CENP-A (1)
- CERN LHC Coll (1)
- CIS+ (1)
- CMR (1)
- COMT VAL(158)MET polymorphism (1)
- COPD diagnosis (1)
- CORM (1)
- CPP Peptide (1)
- CPP-peptide (1)
- CSE4, CENP-A (1)
- CSF (1)
- CSF-1 Rezeptor (1)
- CSF-1 receptor (1)
- CT-INT (1)
- CXCL8 (IL-8) (1)
- Caco-2 (1)
- Calcineurin (1)
- Calciumtransport (1)
- Camponotus (1)
- Camponotus floridanus (1)
- Cancer (1)
- Carcinogenität (1)
- Cardiovascular risk factors (1)
- Caspase 12 (1)
- Cerebral blood flow (1)
- Cerebral vasospasm (1)
- Chaos (1)
- Chaostheorie (1)
- Chaotisches System (1)
- Charcot-Marie-Tooth (1)
- Charcot-Marie-Tooth disease (1)
- Charcot–Marie–Tooth disease (1)
- Chemotherapie (1)
- Chemotherapy (1)
- Chondrozyten (1)
- Circadian Rhythms (1)
- Circadiane Rhythmik (1)
- Cis-elements (1)
- Cisterna magna (1)
- City Planning in the USA (1)
- Click-Chemie (1)
- Climate change (1)
- Cluster-Entwicklung (1)
- Cobaltate (1)
- Cobaltates (1)
- Coexpression (1)
- Cognitive (1)
- Coherent 2D Spectroscopy (1)
- Colloids (1)
- Combination (1)
- Commercial preparations (1)
- Compressed Sensig (1)
- Computational chemistry (1)
- Computersimulation (1)
- Cone-beam CT (1)
- Conjugate gradient method (1)
- Contaminants (1)
- Coronary artery bypass graft (1)
- Cortison (1)
- Cryolesion (1)
- Crystalloids (1)
- Cuprates (1)
- Cushings syndrome (1)
- Cyclooctine (1)
- Cyclooctyne (1)
- Cymantren (1)
- Cystic fibrosis (1)
- Cytotoxizität (1)
- DCA (1)
- DNA Methylation (1)
- DNA Reparatur (1)
- DNA repeat expansion (1)
- DNA replication (1)
- DNA-binding vesicles (1)
- DNS-Reparatur (1)
- DOT1 (1)
- DRD2 (1)
- Danish hernia database (1)
- Darmkrebs (1)
- Database (1)
- Datenbanksystem (1)
- Decision-making (1)
- Defensine (1)
- Delay-Differential Equations (1)
- Delayed snowmelt (1)
- Demenz (1)
- Dendrimer (1)
- Depression (1)
- Design (1)
- Diabetes (1)
- Diabetes Typ 1 (1)
- Diarylethen (1)
- Diarylethene (1)
- Diarylethylene (1)
- Dickblattgewächse (1)
- Dielektrikum (1)
- Dimension 2 (1)
- Dimeric Naphthylisoquinoline Alkaloids (1)
- Dimermethode (1)
- Direkte numerische Simulation (1)
- Diskursanalyse (1)
- Dissipatives System (1)
- Disulfidbrücken (1)
- Domänenprotein (1)
- Dopamin (1)
- Double hemorrhage model (1)
- Drahtloses Sensorsystem (1)
- Dreiecksgitter (1)
- Driver Assistance System (1)
- Driving (1)
- Drogen (1)
- Duftintensität (1)
- Duftstoff (1)
- Dynamic Geometry Environment (1)
- Dynamic Memory Management (1)
- Dynamische Geometriesysteme (1)
- Dynamische Speicherverwaltung (1)
- Dynamisches System (1)
- E. coli Nissle 1917 (1)
- E3 14.7-kilodalton protein (1)
- E3 ubiquitin ligase (1)
- EBRT (1)
- ECG-recording (1)
- ECORN-CF Projekt (1)
- EHS classification (1)
- EMG (1)
- EORTC-BN20 (1)
- EORTC-QLQ-C15-PAL (1)
- EP Procedures (1)
- ERK signaling (1)
- ERP-BCI (1)
- ERPS (1)
- ETR (1)
- Echinococcus multilocularis (1)
- Echtzeitsystem (1)
- Ecological Momentary Assessment (1)
- Eierstockkrebs (1)
- Eindrucksbildung (1)
- Eingebettetes System (1)
- Einzelhandel (1)
- Eisen-basierte Supraleiter (1)
- Electromagnon (1)
- Electronic diary (1)
- Electrospinning (1)
- Elektrizitätserzeugung (1)
- Elektromagnon (1)
- Elektromigration (1)
- Elektronenflüssigkeit (1)
- Elektronengas (1)
- Elektronenstrahllithographie (1)
- Elektronentransfer (1)
- Elektronisches Tagebuch (1)
- Elektrostatisches Verspinnen (1)
- Elementarteilchenphysik (1)
- Embedded Systems (1)
- Embryo (1)
- Embryonalentwicklung (1)
- Emery-Dreifuss muscular dystrophy (1)
- Encephalomyelitis (1)
- Endogenous Glucocorticoids (1)
- Energie (1)
- Energielandschaft (1)
- Entscheidung (1)
- Entscheidungsprozess (1)
- Entzündung (1)
- Epigenese (1)
- Epigenetic (1)
- Epigenetik (1)
- Epitaxieschicht (1)
- Erysiphe graminis (1)
- Erythropoietin (1)
- Escherichia coli (1)
- European beech (1)
- European countries (1)
- European experience (1)
- Evakuierung (1)
- Excitotoxicity (1)
- Experimental brain trauma (1)
- Experimentellen Autoimmun-Enzephalomyelitis (1)
- Extended field irradiation (1)
- Extremwerttheorie (1)
- Extremwetterereignisse (1)
- Exziton (1)
- FAS (1)
- FAS-II (1)
- FGF (1)
- FGF Signaling (1)
- FIR-Spektroskopie (1)
- FMRI (1)
- FXII (1)
- FabI (1)
- FabV (1)
- Fabry disease (1)
- Factor XII (1)
- Fahren (1)
- Fahrerassistenz (1)
- Faktor XII (1)
- Fanconi Anemia (1)
- Fanconi Anämie (1)
- Fanconi-anemia subtype (1)
- Farbstoff (1)
- Fe3O4 (1)
- Femtosekundenspektroskopie (1)
- Fermionensystem (1)
- Fernerkundung (1)
- Fernwartung (1)
- Festkörperphysik (1)
- Festkörpertheorie (1)
- Fettsäurebiosynthese (1)
- Fettsäurestoffwechsel (1)
- Fibroblasten (1)
- Fibroblastenwachstumsfaktor (1)
- Flowering (1)
- Fluency (1)
- Fluidnetzwerk (1)
- Fluor-19 (1)
- Fluoreszenz (1)
- Fluoreszenzmikrosopie (1)
- Foamy virus (1)
- Follicular lymphoma (1)
- Fontan’s Operation (1)
- Forschung und Entwicklung (1)
- Fotovoltaik (1)
- Frabin/Fgd4 (1)
- Frame-based (1)
- Frame-less (1)
- Freies Molekül (1)
- Frequency Domain (1)
- Front Collision Warning (1)
- Frontkollisionswarnung (1)
- Fumonisin B1 (1)
- Fumonisine (1)
- Functional interaction (1)
- Functional module search (1)
- Functional modules (1)
- Funktionelle Bildgebung (1)
- Funktionelle Modulsuche (1)
- G protein coupled receptor (1)
- G-Protein gekoppelte Rezeptoren (1)
- GABA (1)
- GABA A Receptors (1)
- GABA A Rezeptoren (1)
- GABA(A) receptors (1)
- GABAA-Rezeptor (1)
- GABP (1)
- GATA4 (1)
- GMSB model (1)
- GO1 (1)
- GOLD (1)
- GRN (1)
- GagPol fusion protein (1)
- Gametozyt (1)
- Gammaastronomie (1)
- Garcinia biflavonoids (1)
- Gaudium et Spes (1)
- Gedächtnis (1)
- Geldpolitik (1)
- Gen (1)
- Gen Umweltinteraktion (1)
- Gen notch (1)
- Genomische Bildgebung (1)
- Genotoxizität (1)
- Genregulation (1)
- Geoinformationssystem (1)
- Gephyrin (1)
- Gerinnungsfaktor XII (1)
- Germanium (1)
- Gerste (1)
- Geschmack (1)
- Geschmackssinn (1)
- Gesundheitswesen (1)
- Gewebe (1)
- Geweberegeneration (1)
- Gliom (1)
- Glioma (1)
- Globale Optimierung (1)
- Glucosetransportproteine (1)
- GlyRs (1)
- Glycine Receptors (1)
- Glycoengineering (1)
- Glycosyltransferase (1)
- Glyzin Rezeptoren (1)
- Glyzinrezeptor (1)
- Gold (1)
- Graft-versus-host disease (1)
- Graphene (1)
- Grassmann Manifold (1)
- Grassmann-Mannigfaltigkeit (1)
- Guanin Nukleotid Austauschfaktor (1)
- Guaninnucleotid-Austauschfaktoren (1)
- Göttingen (1)
- H.264 SVC (1)
- H.264/SVC (1)
- HBD2 (1)
- HBL (1)
- HBO (1)
- HD5 (1)
- HES (1)
- HIV-1; subtype C; proviral plasmid; viral replication; resistance assays; Vpu; CD317; CD4 (1)
- HLA (1)
- HMI (1)
- HPLC-MS/MS method (1)
- HRAS (1)
- HaCaT cells (1)
- Hadron-Hadron Scattering (1)
- Halbleiterlaser (1)
- Halbleiteroberfläche (1)
- Handelsgeographie (1)
- Hautkrebs (1)
- Helicobacterpylori (1)
- Helminths (1)
- Heparin (1)
- Hepatitis C infection (1)
- Hepatotoxizität (1)
- Herbivor-Parasitoid Interaktion (1)
- Herz (1)
- Herzentwicklung (1)
- Herzhypertrophie (1)
- Heterostrukturen (1)
- Hfq (1)
- HgTe (1)
- Hidden Markov Model (1)
- Higgs boson signal (1)
- Hilfe-System (1)
- Hochauflösendes Verfahren (1)
- Hochtemperatursupraleitung (1)
- Holliday junction reolvass (1)
- Hormone Receptor Signaling (1)
- Hospitalization (1)
- Housing (1)
- Human papillomavirus (1)
- Humorale Immunität (1)
- II type-2 receptor (1)
- IL-12 production (1)
- IL-17 (1)
- IL-4 (1)
- IL-4 Rezeptor alpha (1)
- IL-4 receptor alpha chain (1)
- IL28B (1)
- IMpACT (1)
- IVF-methods (1)
- Image Registration (1)
- Imatinib (1)
- Imd pathway (1)
- Immobilienmarkt (1)
- Immunisierung (1)
- Immunmodulation (1)
- Immunoadsorption (1)
- Immunoapheresis (1)
- Immunologie (1)
- Immunomodulation (1)
- Immunsystem (1)
- Impfstoff (1)
- Impfung (1)
- Impulslaserbeschichten (1)
- Incommensurate spin structure (1)
- Infectious disease (1)
- Inferior vena cava (1)
- Inflammation (1)
- Influenza (1)
- Informationsverarbeitung (1)
- Inkommensurable Zykloide (1)
- Innovation (1)
- Insulin (1)
- Insulinrezeptor (1)
- Insulinsignalweg (1)
- Integrase (1)
- Integrated Knowledgebase (1)
- Integrierte Datenbank (1)
- Inter-observer variability (1)
- Interactive Help System (1)
- Interaktion (1)
- Interferon <gamma-> (1)
- Interleukin 12 (1)
- Interleukin 6 (1)
- Internationaler Konflikt (1)
- Intrazelluläre Symbiose (1)
- Invasion (1)
- Inverse Probleme (1)
- JES (1)
- Japanese population (1)
- Japankärpfling (1)
- KATP channel (1)
- Kapazität (1)
- Kardial Hypertrophy (1)
- Katholische Kirche (1)
- Keldysh Formalismus (1)
- Keramischer Supraleiter (1)
- Kernspintomografie (1)
- Kerntransport (1)
- Kirche (1)
- Kleinkern (1)
- Klima (1)
- Klimamodellierung (1)
- Klimaschutz (1)
- Klimaschutzkonzept (1)
- Klimaschwankung (1)
- Knochendichte (1)
- Knochenstoffwechsel (1)
- Knockout-Maus (1)
- Knorpelzelle (1)
- Knowledge Management System (1)
- Knowledge-based System (1)
- Kognitive Kontrolle (1)
- Kohärente 2D Spektroskopie (1)
- Kohärente Optik (1)
- Kombinationstherapie (1)
- Konfliktlösung (1)
- Konforme Feldtheorie (1)
- Konjugate (1)
- Konjugierte-Gradienten-Methode (1)
- Koran (1)
- Korruption (1)
- Kraftfeld-Rechnung (1)
- Krebs <Medizin> (1)
- Kreditmarkt (1)
- Kristallwachstum (1)
- Kulturelle Identität <Motiv> (1)
- Kuprate (1)
- Kutikularwachs (1)
- Körper <Motiv> (1)
- L cells (1)
- LIFR (1)
- LMNA mutations (1)
- LPHN3 (1)
- LTD (1)
- LaAlO3 (1)
- LaVO3 (1)
- Ladungstransfer (1)
- Lamto Reserve (1)
- Land use (1)
- Landkreis (1)
- Landschaft (1)
- Large Hadron Collider (1)
- Leber (1)
- Lebertoxizität (1)
- Leishmania (1)
- Leukaemia-inhibitory factor (1)
- Levothyroxine (1)
- Lin9 (1)
- Lipidmembran (1)
- Ljapunov-Funktion (1)
- Ljapunov-Stabilitätstheorie (1)
- Localization (1)
- Lokalisation (1)
- Lung Cancer metastasis (1)
- Lung cancer (1)
- Luttinger liquide (1)
- Luttinger-Flüssigkeit (1)
- Lyapunov Funktion (1)
- Lyapunov functions (1)
- MAGIC-Teleskop (1)
- MAP3K4 (1)
- MBE (1)
- MC expectation (1)
- MC program (1)
- MCPH1 (1)
- MK801 (1)
- MR guidance (1)
- MRSA (1)
- MS (1)
- MYB (1)
- Macrophage (1)
- Magnetfeld (1)
- Magnetischer Sensor (1)
- Magnetoelectric effect (1)
- Magnetoelektrischer Effekt (1)
- Magnon (1)
- Majorana Zustände (1)
- Makrophagen (1)
- Management System (1)
- Management-Systeme (1)
- Manganate (1)
- Manganverbindungen (1)
- Marker (1)
- Martensit (1)
- Mass Isotopomers Distribution Analysis (1)
- Massen-Isotopomer Verteilungs-Analyse (1)
- Mast cells (1)
- Mastzelle (1)
- Mathematikunterricht (1)
- Mausmodell (1)
- Maximum Entropy Algorithmus (1)
- Maximum Entropy algorithm (1)
- Maße für Quantenverschränkung (1)
- Medienanalyse (1)
- Medienkommunikation (1)
- Mehrpfadübertragung (1)
- Mehrschichtnetze (1)
- Mehrschichtsystem (1)
- Mehrskalenmodell (1)
- Melanophor (1)
- Melatonin (1)
- Memory (1)
- Meningioma (1)
- Merocyanin (1)
- Merocyanine (1)
- Mesh Augmentation (1)
- Messenger-RNS (1)
- Metabolic Flux Analysis (1)
- Metabolic pathways (1)
- Metabolic profiles (1)
- Metabolische Flux-Analyse (1)
- Metall-Isolator-Phasenumwandlung (1)
- Metallorganische Verbindungen (1)
- Metastasierung (1)
- Methodenentwicklung (1)
- Methylierung (1)
- Methylphenidat (1)
- Mexico (1)
- Mexiko (1)
- Mice (1)
- Michael addition (1)
- Michael-Addition (1)
- Micro-Hall Magnetometry (1)
- Micro-SQUID (1)
- Microarray (1)
- Microcirculation (1)
- Micromonospora (1)
- Mikro-SQUID (1)
- Mikrohallmagnetometrie (1)
- Milnesium tardigradum (1)
- Minischwein (1)
- Mitose (1)
- Mittelmeer (1)
- Mittelmeerraum (1)
- Miz1 (1)
- Mobile technology (1)
- Mobiler Roboter (1)
- Molecular probes (1)
- Molekularelektronik (1)
- Molekularstrahlepitaxie (1)
- Molybdän (1)
- Molybdäncarbonyle (1)
- Monetary Policy (1)
- Monetary Union (1)
- Monoklonaler Antikoerper (1)
- Monte Carlo methods (1)
- Monte Carlo simulation (1)
- Motoneuron (1)
- Motor cortex (1)
- Motor plasticity (1)
- Mott-Schottky Analyse (1)
- Multi-Layer (1)
- Multiferroikum (1)
- Multipath Transmission (1)
- Multiple sclerosis (1)
- Multiwellenlängen (1)
- Muskelkraft (1)
- Mutagenität (1)
- Mycobacterium caprae (1)
- Mycobacterium tuberculosis complex (1)
- Mycoplasma (1)
- Myelin (1)
- Myeloblast (1)
- Myeloide Suppressorzellen (1)
- Mykotoxin (1)
- Myon (1)
- N-Myc down regulated gene 1 (1)
- N-RAS (1)
- N170 (1)
- NA/I symporter (1)
- NADPH oxidase (1)
- NADPH oxidases (NOX) (1)
- NCAM1 (1)
- NDVI (1)
- NF-kappa-B (1)
- NF-κB (1)
- NFATc (1)
- NFATc1/αA (1)
- NI(111) (1)
- NIH-3T3 (1)
- NMDA-Antagonist (1)
- NMDA-Rezeptor (1)
- NMDAR (1)
- NMO-IGG (1)
- NMR-Bildgebung (1)
- NMR-Tomographie (1)
- NP-hardness (1)
- NRPS (1)
- Nahfeldoptik (1)
- Nail unit (1)
- Nanodraht (1)
- Nanoelektromechanik (1)
- Nanoelektromechanische Systeme (1)
- Nanofaser (1)
- Nanooptic (1)
- Naphthochinonen (1)
- Naphthoquinones (1)
- Nephrotoxizität (1)
- Nervendegeneration (1)
- Nervennetz (1)
- Nervenzelle (1)
- Network Analysis (1)
- Networks (1)
- Netzwerk (1)
- Netzwerkalgorithmen (1)
- Neurobiologie (1)
- Neurodegeneration (1)
- Neuropathie (1)
- Neuropsychologie (1)
- Neurotransmitter Receptors (1)
- Neurotransmitter Rezeptoren (1)
- Neurotransmitter-Rezeptor (1)
- Neuseeland (1)
- New mexico (1)
- Newton Methods (1)
- Newton method (1)
- Newtonverfahren (1)
- Next generation sequencing (1)
- Nicht-Transparente Medien (1)
- Nicht-kleinzelliges Bronchialkarzinom (1)
- Nichtkonvexe Optimierung (1)
- Nichtlineare Kontrolltheorie (1)
- Nichtlineares System (1)
- Nichtlineares dynamisches System (1)
- Niederschlag (1)
- Nigeria (1)
- Niveaustufen des Beweises (1)
- Non-Small Cell Lung Cancer (1)
- Non-transparency (1)
- Nonlinear Dynamics (1)
- Notfall (1)
- Nothotaxa (1)
- Nukleäre Hormonrezeptoren (1)
- OIS (1)
- OPUS (1)
- OSMR (1)
- Oberflächenfunktionalisierung (1)
- Oberflächenphysik (1)
- Oberflächenplasmonresonanz (1)
- Oberflächenproteine der Sexualstadien (1)
- Odour Intensity (1)
- Olfaction (1)
- Olfactory (1)
- Oligofructoside (1)
- Oncostatin M (1)
- Onkogen (1)
- Optimierung (1)
- Optimization on Lie Groups (1)
- Organische Solarzelle (1)
- Organometall-Komplexe (1)
- Ovarialkarzinom (1)
- Ovarian Cancer (1)
- Oxid (1)
- Oxidativer Stress (1)
- Oxide (1)
- O–I 1 fluorescence rise (1)
- P15(INK4B) (1)
- P21 (1)
- P300-Speller (1)
- P67(PHOX) (1)
- PALM (1)
- PAR (1)
- PARM (1)
- PBPK/PBTK model (1)
- PDF set (1)
- PDI (1)
- PG neurons (1)
- PIK3CA mutations (1)
- PLD (1)
- POZ domain (1)
- PPAR-gamme (1)
- PRMT5 (1)
- PRRT (1)
- PTPN22 (1)
- Pain (1)
- Papier-Solarzelle (1)
- Parasit (1)
- Parathormon (1)
- Parkinsons disease (1)
- Parkinson’s disease (1)
- Path Computation Element (1)
- Patulin (1)
- Pediatric (1)
- Peptide receptor radionuclide therapy (1)
- Perception (1)
- Perforine (1)
- Performance Modeling (1)
- Persistenz (1)
- Person Perception (1)
- Perylenbisimid (1)
- Perylene bisimide (1)
- Pfadberechnungselement (1)
- Phage Display (1)
- Phase II trial (1)
- Phasenumwandlung (1)
- Phosphoproteomic analysis (1)
- Photochemie (1)
- Photochemistry (1)
- Photochromie (1)
- Photorezeption (1)
- Photostrom (1)
- Phylogenie (1)
- Physikalische Eigenschaft (1)
- Physikalische Zeit (1)
- Physiologie (1)
- Physiology (1)
- Planung (1)
- Plasmodium falciparum (1)
- Platelet activating Factor (1)
- Platelets (1)
- Plättchennetzwerk (1)
- Plättchenphosphoproteom (1)
- Pnictide (1)
- Polarisationspulsformung (1)
- Polarisiertes Licht (1)
- Polychromophores System (1)
- Polymere (1)
- Polyomaviren (1)
- Polyomavirus JC (1)
- Pontryagin Maximum Principle (1)
- Pontryagin Maximum Prinzip (1)
- Populorum Progressio (1)
- Pore formation (1)
- Pore-formation (1)
- Porifera (1)
- Postcolonial literature (1)
- Postkoloniale Literatur (1)
- Pragmatik (1)
- Predictors (1)
- Prednisolon (1)
- Preemptive-strike (1)
- Prefrontal cortex (1)
- Prevalence (1)
- Probiotic (1)
- Probiotikum (1)
- Proof (1)
- Prostatakrebs (1)
- Protein Disulfid Isomerase (1)
- Protein p53 (1)
- Proteinfaltung (1)
- Proteinkinasen (1)
- Proteinsynthese (1)
- Proteomanalyse (1)
- Proteome (1)
- Proving Level (1)
- Prozessierung (1)
- Prädiktor (1)
- Präfrontaler Kortex (1)
- Präparative organische Chemie (1)
- Prävalenz (1)
- Psychiatrie (1)
- Psychologische Diagnostik (1)
- Psychologische Sicherheitsforschung (1)
- Psychology (1)
- Ptpn22 (1)
- QCD (1)
- QCD background (1)
- QDTI (1)
- QMC (1)
- QUAC (1)
- QoE (1)
- Quality-of-Experience (1)
- Quanten Spin Hall Effekt (1)
- Quanten-Hall-Effekt (1)
- Quantenchemie (1)
- Quantenfeldtheorie (1)
- Quantenkontrolle (1)
- Quantenmechanisches System (1)
- Quantenspinsystem (1)
- Quantum dynamics (1)
- Quantum spin Hall (1)
- Quecksilbertellurid (1)
- Quran (1)
- R factor = 0.018 (1)
- R factor = 0.025 (1)
- R factor = 0.027 (1)
- R-715 (1)
- RAD51C (1)
- REST (1)
- RNA (1)
- RNA denaturation (1)
- RNA sequencing (1)
- RNA structure (1)
- RNA synthesis (1)
- RNA-polymerase-II (1)
- Radioastronomie (1)
- Radiotherapy (1)
- Rare earth manganites (1)
- Rashba effect (1)
- Rashba-Effekt (1)
- Rat (1)
- Ratte (1)
- Rauschgift (1)
- Real-Time Operating Systems (1)
- Receptor Anchoring (1)
- Receptor Preference (1)
- Recombinant defensins (1)
- Regeneration (1)
- Registrierung <Bildverarbeitung> (1)
- Regulation of protease activity (1)
- Regulatorischer T-Lymphozyt (1)
- Regulatory T-cell (1)
- Rekombinante DNS (1)
- Rekombination (1)
- Rekonstruktion (1)
- Remote sensing (1)
- Renal cell carcinoma (1)
- Repression <Genetik> (1)
- Resilience (1)
- Resonanzstreuung (1)
- Resource Management (1)
- Respiration correlated imaging (1)
- Ressourcenallokation (1)
- Ressourcenmanagement (1)
- Resveratrol (1)
- Rezeptor Verankerung (1)
- Rho (1)
- Rho-GTPase Cdc42 (1)
- Ribosomale RNA (1)
- Riemannian optimization (1)
- Riemannsche Geometrie (1)
- Riemannsche Optimierung (1)
- Ring closing metathesis (1)
- Ringschlussmetathese (1)
- Risikoindex (1)
- Ruthenate (1)
- Röntgen-Photoelektronenspektroskopie (1)
- Röntgenastronomie (1)
- Rüsselkäfer (1)
- SAS <Programm> (1)
- SCF (1)
- SER/THR kinase (1)
- SGLT1 (1)
- SIRP-alpha (1)
- SKP1 (1)
- SLAC/SLAH (1)
- SLX4 (1)
- SM Background (1)
- SM proteins (1)
- SOD1 mutations (1)
- SST (1)
- ST1797 (1)
- ST88 (1)
- STAIR (1)
- SUSY breaking scale (1)
- SVR (1)
- SWI/SNF (1)
- SacB (1)
- Sahel (1)
- Salmonella (1)
- Salmonella enterica (1)
- Salmonella typhimurium (1)
- Salmonella-containing vacuole (1)
- Sandwich-Verbindungen (1)
- Savanna (1)
- Savannas (1)
- Schilddrüse (1)
- Schilddrüsenhormontherapie (1)
- Schlaganfall (1)
- Schwann cells (1)
- Scleroderma (1)
- Secondary traumatic brain damage (1)
- Secretion (1)
- Sedum rupestre L. subsp. erectum ‘t Hart (1)
- Selbstorganisation (1)
- Selbstverteidigung (1)
- Selbstverteidigung <Völkerrecht> (1)
- Self-Trapping (1)
- Self-defense (1)
- Seltene Erden (1)
- Seltenerdverbindungen (1)
- Semiconductor Lasers (1)
- Seneszenz (1)
- Sensory (1)
- Sepsis (1)
- Sequenz (1)
- Serengeti (1)
- Serotonintransporter (1)
- Sexuelle Entwicklung (1)
- Short dsRNA oligonucleotides (1)
- Sialic acids (1)
- Sialinsäuren (1)
- Signalkette (1)
- Signaltransduktion (1)
- Silicium (1)
- Similarity (1)
- Simkania Negevensis (1)
- Single-Molecule Transistor (1)
- Small RNA (1)
- Small nuclear RNP (1)
- Smartphone (1)
- Social Influence (1)
- Software (1)
- Somatostatin receptor (1)
- South Africa (1)
- Sozialer Einfluss (1)
- Sozialethik (1)
- Soziallehre (1)
- Sozialpsychologie (1)
- Species distribution modeling (1)
- Spectrofluorimetry (1)
- Speicher <Informatik> (1)
- Spezialisierung (1)
- Spin-Bahn-Wechselwirkung (1)
- Spinal metastasis (1)
- Spir (1)
- Spitzwegerich (1)
- Stabilität (1)
- Stadtplanung (1)
- Stammzelle (1)
- Standardmodell (1)
- Standortpolitik (1)
- Stat5 (1)
- State-Space Models (1)
- Stereotactic (1)
- Stereotactic body radiotherapy (1)
- Stereotype (1)
- Stereotypes (1)
- Steuerbarkeit (1)
- Stim (1)
- Stochastic Algorithms (1)
- Stochastische Optimierung (1)
- Stoffwechsel (1)
- Strassentunnel (1)
- Streptococcus pneumoniae (1)
- Stressreaktion (1)
- Stringtheorie (1)
- Strong correlations (1)
- Struktur (1)
- Struktur-basiertes Wirkstoff Design (1)
- Subarachnoid (1)
- Subarachnoid hemorrhage (1)
- Suc1 (1)
- Sumo (1)
- Sumoylierung (1)
- Superconductivity (1)
- Suppressorzelle (1)
- Surface plasmons (1)
- Synapse (1)
- Synchronisierung (1)
- Synchronization (1)
- Synthesis (1)
- Systems Biology (1)
- T = 173 K (1)
- T = 199 K (1)
- T cell development (1)
- T cell homing (1)
- T cell receptor (1)
- T helper cell (1)
- T(H)17 cells (1)
- T-Lymphozyten-Rezeptor (1)
- T-PA (1)
- T-Zellhoming (1)
- T-antigen (1)
- T-cell reactivity (1)
- T1 (1)
- T3s (1)
- TGF-BETA (1)
- TGN1412 (1)
- TIC disorder (1)
- TMS (1)
- TNF-R1 (1)
- TNF-R2 (1)
- TNF-alpha (1)
- TNF-α (1)
- TO-target interval (1)
- TOJ (1)
- TRPC6 (1)
- Tabu-Search (1)
- Tanzania (1)
- Tapeworm (1)
- Taste (1)
- Temperatur (1)
- Terahertz (1)
- Terahertz spectroscopy (1)
- Terrylenbisimid (1)
- Terrylenderivate (1)
- Terrylene bisimide (1)
- Text Mining (1)
- Theoretische Chemie (1)
- Therapie (1)
- Thiostrepton (1)
- Thrombectomy (1)
- Thrombozytenaggregation (1)
- Tiergesellschaft (1)
- Time Series Analysis (1)
- Time hole (1)
- Topolgical Phase (1)
- Topological Insulator (1)
- Topologische Isolatoren (1)
- Topologischer Isolator (1)
- Topology (1)
- Total nodal irradiation (1)
- Toulmin Modell (1)
- Toxikologie (1)
- Translokation (1)
- Transmissionsblockierende Impfstoffe (1)
- Transplantat-Wirt-Reaktion (1)
- Trend test (1)
- Triclosan (1)
- Trigger System (1)
- Tuberkulose (1)
- Tumor thrombus (1)
- Tumor-Nekrose-Faktor <alpha> (1)
- Tunnel emergencies (1)
- Tunneling spectroscopy (1)
- Typ 1 (1)
- Type 1 diabetes (1)
- USA (1)
- UV-VIS-Spektroskopie (1)
- Ultrafast spectroscopy (1)
- Ultrakurzzeit Spektroskopie (1)
- Ultrakurzzeitspektroskopie (1)
- Ultraschall (1)
- Ultraschalldiagnostik (1)
- Umweltgefährdung (1)
- United States (1)
- Univted-States (1)
- Unternehmenskooperation (1)
- Unwetter (1)
- Uzbekistan (1)
- VAL66MET polymorphism (1)
- Vaccine (1)
- Vaccinia Virus Replikation (1)
- Vaccinia virus (1)
- Variationsrechnung (1)
- Variovorax paradoxus (1)
- Vektorboson (1)
- Verarbeitungsflüssigkeit (1)
- Verbrauch (1)
- Verbreitungsgrenzen (1)
- Verfahren der konjugierten Gradienten (1)
- Verhalten (1)
- Verkehrspsychologie (1)
- Verkehrsunfall (1)
- Verschränkung (1)
- Verteiltes System (1)
- Vertretbarkeit (1)
- Video Streaming (1)
- Videoübertragung (1)
- Virtuelle Realitaet (1)
- Visualisierung (1)
- Visualization (1)
- Vorurteil (1)
- WISP1/CCN4 (1)
- WNT signaling pathway (1)
- WW (1)
- WZ production (1)
- Wachstum (1)
- Wahrnehmung (1)
- Warnung (1)
- Warteschlangennetz (1)
- Weisheit (1)
- West-Africa (1)
- Wetter (1)
- Wireless Sensor/Actuator Systems (1)
- Wirkstofffreisetzung (1)
- Wirkungsquerschnitt (1)
- Wisdom and Justifiability (1)
- Wissensbanksystem (1)
- Wissensmanagement (1)
- Wohnbau (1)
- Währungsunion (1)
- Wärmekraftwerk (1)
- Würmer (1)
- XA (1)
- Xmrk (1)
- Yersinia (1)
- Yersinia pestis (1)
- Yolk protein (1)
- Z Boson (1)
- Z boson (1)
- Zebrabärbling (1)
- Zeitdifferenzierung (1)
- Zeitoptimale Regelung (1)
- Zelladhäsion (1)
- Zelltransport (1)
- Zellzyklus (1)
- Zusammenstoss (1)
- Zustandsraummodelle (1)
- a-posteriori error estimates (1)
- abdominal (1)
- abdominal wall hernia (1)
- abdominal wall surgery (1)
- abiotic formation (1)
- abscisic acid (1)
- absolute configuration (1)
- accelerated atherosclerosis (1)
- acetivorans C2A (1)
- acoustic communication (1)
- acoustic startle (1)
- actin cortex (1)
- actin cytoskeleton (1)
- actinomycetes (1)
- action planning (1)
- action-effects (1)
- activated-receptor gamma (1)
- activation (1)
- activation mechanism (1)
- acute ischemic stroke (1)
- acute myeloid leukemia (1)
- acute renal failure (1)
- adaptation (1)
- adaption (1)
- adaptive refinement (1)
- addiction (1)
- addicts (1)
- additional jet (1)
- adenovirus (1)
- adhesion (1)
- adipose tissue (1)
- adjuvant hormonal treatment (1)
- adolescence (1)
- adsorption (1)
- adult bee (1)
- adult drosophila (1)
- age (1)
- age-related osteoporosis (1)
- agency (1)
- aging (1)
- aging brain (1)
- agnoists (1)
- agonist (1)
- airway (1)
- akt (1)
- alagille syndrome (1)
- alias pilot trial (1)
- alignment (1)
- alkaline-phosphatase (1)
- alleles (1)
- alpha galactosidase (1)
- alpha-synuclein (1)
- alternative Konfliktlösung (1)
- alveoar echinococcosis (1)
- alveolar epithelium in vitro model, claudin-1, claudin-3, claudin-4, claudin-5 (1)
- aminoacyl-transfer-RNA (1)
- amplitude (1)
- amygdala (1)
- amyloid beta (1)
- amyotrophic lateral sclerosis (1)
- anal atresia (1)
- anaplastic large cell lymphoma (1)
- anemia (1)
- anesthetics (1)
- aneuploidy (1)
- aneurysm repair (1)
- angiography (1)
- angioplasty (1)
- angiotensin II (1)
- animal communication (1)
- animal ecology (1)
- animal model (1)
- animal models (1)
- animal-model (1)
- anion channel (1)
- annihilation (1)
- anoikis (1)
- anomaly mediation (1)
- anorectal malformation (1)
- ant communities (1)
- anterior insula (1)
- anthocyanins (1)
- anthropogenic noise (1)
- anti inflammation (1)
- anti-aquaporin-4 antibody (1)
- anti-proliferative effects (1)
- anti-protease (1)
- anti-tumor agents (1)
- antibacterial activity (1)
- antibiotic resistance (1)
- antibodies (1)
- antibody (1)
- anticipation (1)
- anticipatory mechanisms (1)
- antidepressant (1)
- antigen (1)
- antigen expression (1)
- antigen presentation (1)
- antigen-B (1)
- antimicrobial (1)
- antimicrobial activity (1)
- antioxidant (1)
- antisense RNA (1)
- antisense RNAs (1)
- ants (1)
- anxiety like (1)
- aortic-valve (1)
- apolipoprotein E (1)
- appliances (1)
- approximation algorithm (1)
- aquaporin 3 protein (1)
- aquaporin-4 autoantibodies (1)
- aquired resistance (1)
- arabidopsi (1)
- arabidopsis (1)
- arabidopsis thaliana (1)
- arabidpsis thaliana (1)
- aral sea basin (1)
- archwires (1)
- area (1)
- arf (1)
- arginine methylation (1)
- arm (1)
- artery occlusion (1)
- arthritis (1)
- aryl hydrocarbon receptor (AhR) (1)
- asbestos (1)
- asparaginase (1)
- asparagine (1)
- asparagine synthetase (1)
- aspergillosis (1)
- assessment (1)
- assisitvetechnology (1)
- assisted reproductive techniques (1)
- associative learning (1)
- astrocyte (1)
- astrocytic tumor (1)
- astroglia (1)
- astrogliosis (1)
- atherothrombosis (1)
- atomic-force microscopy (1)
- atrial fibrillation (1)
- atrial natriuretic peptide (1)
- attention (1)
- auditory discrimination (1)
- auditory masking (1)
- aureus infections (1)
- auto-calibration (1)
- autologous chondrocyte implantation (1)
- autophagy (1)
- avaliação de risco (1)
- axial skeletal defects (1)
- axonal degeneration (1)
- axonopathic changes (1)
- bZIP (1)
- bacillus calmette guerin (1)
- back pain (1)
- background (1)
- background cross section (1)
- background expectation (1)
- bacterial meningitis (1)
- bacterial persistence (1)
- bacterial signal molecule (1)
- bactericidal activity (1)
- balance (1)
- balloon distension (1)
- barley (1)
- baroreflex mechanism (1)
- basal cell (1)
- basin hopping (1)
- beaver-dam eye (1)
- bee larva (1)
- behavior (1)
- behavioral addiction (1)
- benzo[a]pyrene (1)
- beta actin (1)
- bi-steerable robot (1)
- biflavanoids (1)
- big brown bats (1)
- bilayers (1)
- binary tanglegram (1)
- biocompatibility (1)
- bioconjugate (1)
- bioengineering (1)
- biogenic amines (1)
- biolabelling (1)
- biomarker (1)
- bioorganometallic chemistry (1)
- bipolar disorder (1)
- birth defects (1)
- bitter taste (1)
- blastocysts (1)
- bleomicina (1)
- bleomycin (1)
- blood biomarker (1)
- blood brain barrier (1)
- blood sampling (1)
- blood-brain-barrier (1)
- blood-stream forms (1)
- blowfly calliphora-vomitoria (1)
- body <motif> (1)
- bone disease (1)
- bone marrow (1)
- bone metabolism (1)
- bone mineral density (1)
- bone-mineral density (1)
- brain barrier (1)
- brain cancer (1)
- brain computer interface (1)
- brain development (1)
- brain edema (1)
- brain tumours (1)
- brain-computer-interface (1)
- brain–computerinterface (1)
- brucei (1)
- burned savanna (1)
- cEND (1)
- caenorhabditis elegans (1)
- caffeine-induced anxiety (1)
- call (1)
- calorimeter response (1)
- camp signaling pathway (1)
- cancer patients (1)
- cancer-cells (1)
- candidate gene (1)
- canine cancer therapy (1)
- canopy fogging (1)
- capacity (1)
- capsid protein (1)
- carcinogenicity (1)
- cardiac aging (1)
- cardiac arrhythmia (1)
- cardiac fibrosis (1)
- cardiac hyperthrophy (1)
- cardiac protection (1)
- cardiovascular arousal (1)
- cardiovascular disease (1)
- cardiovascular events (1)
- cardiovascular magnetic resonance (1)
- cardiovascular risk factors (1)
- care (1)
- carotid artery (1)
- case-control study (1)
- cased-control studies (1)
- catalytic (1)
- catenin (1)
- catheter tip (1)
- causal belief (1)
- causality (1)
- caveolin-1 (1)
- cavity (1)
- cavity polaritons (1)
- cell adhesion (1)
- cell carcinoma (1)
- cell death (1)
- cell surface (1)
- cell-cycle arrest (1)
- cell-cycle regulation (1)
- cell-line (1)
- cell-penetrating peptides (1)
- cellular-trafficking (1)
- centomeres (1)
- central corneal thickness (1)
- central nervous system (1)
- centromere (1)
- cephalic-vagal influences (1)
- cerebrospina (1)
- cerebrospinal fluid (1)
- cerebrospinal fluid culture (1)
- cerebrospinal-fluid (1)
- chain (1)
- chalinolobus-tuberculatus (1)
- charge misidentification (1)
- chargino --> neutralino pi (1)
- chargino decay (1)
- chargino lifetime (1)
- chargino mass (1)
- charingo mass (1)
- chemistry (1)
- chemosensory protein (1)
- chemosensory system (1)
- childhood cancer (1)
- children born (1)
- chiral boson (1)
- chlorella (1)
- chlorophyll fluorescence (1)
- cholinergic neurons (1)
- choroid-plexus (1)
- chromatin (1)
- chronic kidney disease (1)
- church (1)
- cigarette smoking (1)
- ciliary neurotrophic factor (CNTF) (1)
- ciliolenticular block glaucoma (1)
- circadian photoreception (1)
- circular dichroism (1)
- cis-element modules (1)
- clara cell (1)
- classifiaction (1)
- climate action plan (1)
- climate modelling (1)
- clinical diagnosis (1)
- clinical practice (1)
- clinical trial (1)
- clinical trials (1)
- clock (1)
- cluster (1)
- co-infection (1)
- coa reductase inhibitors (1)
- cochlear implant (1)
- coding strategy (1)
- coexpression (1)
- cognitive control (1)
- coloteral cancer (1)
- commercial preparations (1)
- communication (1)
- community sample (1)
- compartmentalization (1)
- complement factor-H (1)
- complex stability (1)
- computational model (1)
- conditional promoter replacement (1)
- confinement (1)
- conformal field theory (1)
- congenital malformations (1)
- conjugate (1)
- connector (1)
- conservation (1)
- consolidation (1)
- consortium (1)
- contact force (1)
- containing GABA(A) receptors (1)
- containing neurons (1)
- contaminants (1)
- context (1)
- contingent negative-variation (1)
- continuous performance-test (1)
- contralateral breast cancer (1)
- contrast (1)
- contrast-enhanced MRI (1)
- contrast-enhanced ultrasound. (1)
- conversion (1)
- cooperative-oncology-group (1)
- coordination (1)
- copy number variants (1)
- core depression (1)
- coronary artery bypass (1)
- coronary disease (1)
- coronary-heart-disease (1)
- coronene (1)
- cortex (1)
- corticotropin-releasing hormone (1)
- coupling strength (1)
- courtship displays (1)
- crantiectomy (1)
- criteria (1)
- critically ill (1)
- cropland abandonment (1)
- cross section measurement (1)
- cross section time (1)
- cross-sectional studies (1)
- crossing minimization (1)
- crosstalk (1)
- crystal structure (1)
- ctdsp2 (1)
- cubic-monoclinic martensites (1)
- cultivation (1)
- cultural identity (1)
- cultured hippocampal-neurons (1)
- cyanelle (1)
- cymantrene (1)
- cystic fibrosis (1)
- cytogenetic effects (1)
- cytokine (1)
- cytokines (1)
- cytotoxicity (1)
- dSTORM (1)
- damage (1)
- damage cool aid (1)
- dart-poison frog (1)
- data-to-parameter ratio = 14.0. (1)
- data-to-parameter ratio = 14.6 (1)
- data-to-parameter ratio = 20.8 (1)
- data-to-parameter ratio = 22.3 (1)
- database (1)
- dead region (1)
- death (1)
- decay (1)
- decompressive surgery (1)
- deep sequencing (1)
- deep-vein thrombosis (1)
- defective Mitosis (1)
- deficit hyperactivity disorder (1)
- deficit-hyperactivity disorder (1)
- dehydrogenases (1)
- delays progression (1)
- demyelination (1)
- dendrimer (1)
- dental casting alloys (1)
- dentate gyrus (1)
- dependent magnetosensitvity (1)
- depth (1)
- derivates (1)
- derivation (1)
- dermatite flagelada (1)
- dermatitis (1)
- descriptive epidemiology (1)
- deseases (1)
- detector track (1)
- detoxified lipooligosaccharide (1)
- developmental dyslexia (1)
- diabetes (1)
- diagnostic (1)
- diazepinomicin (1)
- differential diagnosis (1)
- diffractive dissociation (1)
- diketopiperazines (1)
- dilepton channel (1)
- dilepton invariant mass (1)
- dilepton invariant mass, (1)
- dilepton mass (1)
- dimer (1)
- dimer method (1)
- dimerer Naphthylisochinolin-Alkaloide (1)
- diphoton invariant mass (1)
- direct pair production (1)
- discourse analysis (1)
- discrete (1)
- disease-modifying therapies (1)
- disorder (1)
- disrupting chemicals (1)
- disruptor endócrino (1)
- dissipative Umgebung (1)
- dissipative environments (1)
- dissociation process, (1)
- district (1)
- disturbance (1)
- disulfide bonds (1)
- dogs (1)
- dosage (1)
- double knockout mice (1)
- double-blind (1)
- doublecortine-like (1)
- drosophila embryo (1)
- drosophila melanogaster (1)
- drosophila mushroom body (1)
- drug addiction (1)
- drug delivery (1)
- drug development (1)
- drug release (1)
- drug research and development (1)
- drug therapies (1)
- drug therapy (1)
- duchenne muscular dystrophy (1)
- dwelling bat (1)
- dyes (1)
- dynamics (1)
- dysfunction (1)
- dyspeptic symptoms (1)
- early diagnosis (1)
- eating disorders (1)
- ecosystem (1)
- electromagnetic calorimeter (1)
- electromigration (1)
- electron energy deposition (1)
- electron probe microanalysis (1)
- electronic states (1)
- electroweak background (1)
- elementary mode analysis (1)
- elements (1)
- elongation (1)
- embolic stroke (1)
- embryonale Maus (1)
- embryonic stem cells (1)
- emission-computed-tomography (1)
- emotional experience (1)
- enatnglement measure (1)
- encephalitis (1)
- endocrine disruptor (1)
- endogenous psychoses (1)
- endogenous shifts of attention (1)
- endothelial cell interactions (1)
- endothelial growth-factor (1)
- endotheliopathy (1)
- energy (1)
- energy conservation (1)
- energy dissipation (1)
- energy expenditure (1)
- energy landscapes (1)
- energy scale (1)
- energy scale uncertainty (1)
- engineered measles-virus (1)
- engineering (1)
- enoxaparin (1)
- entanglement (1)
- environmental phenols (1)
- environmental regulation (1)
- enzyme (1)
- enzyme replacement therapy (1)
- epicutaneous (1)
- epidemic (1)
- epidemiology (1)
- epigastric hernia (1)
- epimutation (1)
- epithelial-mesenchymal transition (1)
- epithelium (1)
- eptesicus-fuscus (1)
- erythropoietin (1)
- escherichia coli K-12 (1)
- estrogen receptor (1)
- estrogens (1)
- eucera berlandi (1)
- eukaryotes (1)
- evacuation behavior (1)
- event rates (1)
- event selcetion cut (1)
- event shape observable (1)
- event shape variable (1)
- event-related potential (1)
- event-related potentials (1)
- event-relatedpotentials (1)
- exchange factor collybistin (1)
- excited state (1)
- exciton (1)
- excitons (1)
- exercise (1)
- experimental (1)
- experimental results (1)
- experimental stroke (1)
- experimental systematic uncertainty (1)
- exposição humana (1)
- expressed sequence tag (1)
- expression pattern (1)
- expression signature (1)
- extensiv transverse myelitis (1)
- extracellular matrix (1)
- extractives (1)
- extrapolation factor (1)
- extreme value theory (1)
- extreme weather event (1)
- eyes (1)
- fMRI (1)
- face perception (1)
- facial expression (1)
- factor 1-alpha (1)
- factor EEF1A2 (1)
- factor H (1)
- factor prevents (1)
- failure (1)
- families (1)
- family (1)
- fear-potentiated startle (1)
- features (1)
- feeding behavior (1)
- fehlerhafte Mitose (1)
- femoral hernia (1)
- femtosecond spectroscopy (1)
- fetal liver (1)
- fibrosis progression (1)
- fiducial cross section (1)
- field gel-electrophoreresis (1)
- fine structure processing (1)
- fission yeast (1)
- fixed-parameter tractability (1)
- flagellar (1)
- flagellate dermatitis (1)
- flagellum (1)
- flavenoids (1)
- flavour changing (1)
- fluid (1)
- fluid networks (1)
- fluorescence detection (1)
- fluorescent protein (1)
- fluoride (1)
- forced-choice (1)
- forest (1)
- forest disturbance (1)
- forest soils (1)
- formaldehyde (1)
- fosfomycin (1)
- fracture (1)
- fragmin (1)
- free radical scavenger (1)
- free-choice (1)
- frontotemporal dementia (1)
- frontotemporal lobar degeneration (1)
- fruit fly (1)
- fumonisin B1 (1)
- functional D-norm (1)
- functional Renormalization Group (1)
- functional absorption cross section of PS II (1)
- functional imaging (1)
- functional neuroanatomy (1)
- functional neuroimaging (1)
- functional renormalization group (1)
- fungos shiitake (1)
- gadofluorine (1)
- gadolinium-DTPA (1)
- gait (1)
- galvanic corrosion (1)
- gametocyte (1)
- gamma (1)
- gamma-aminobutyric-acid (1)
- gamma-interferon (1)
- gene conversion (1)
- gene delivery (1)
- gene environment interaction (1)
- gene family targeting (1)
- geneexpression (1)
- general stress response (1)
- generalized anxiety disorder (1)
- genetic interaction (1)
- genetic loci (1)
- genetic modifiers (1)
- genetic renal disease (1)
- genetics of disease (1)
- genome-wide scan (1)
- genotoxicity (1)
- genotyping (1)
- geometrically linear elasticity (1)
- geometrisch lineare Elastizitätstheorie (1)
- gephyrin (1)
- glaucoma surgery (1)
- glia (1)
- glioblastoma cell-lines (1)
- glioblastoma multiforme (1)
- glomerulonephritis (1)
- glossy11 (1)
- glucagon-like peptide-1 (GLP-1) (1)
- glucokinase (1)
- glut1 (1)
- glv-1h68 (1)
- glycine (1)
- glycoprotein Ib (1)
- go/no-go task (1)
- goldmann applanation tonometer (1)
- good agreement (1)
- gp130 (1)
- gradient (1)
- grading system (1)
- graft surgery (1)
- granulosus (1)
- granzyme B (1)
- gravidez (1)
- growing escherichia coli (1)
- growth factor (1)
- growth rate control (1)
- growth regulator (1)
- growth-factor receptor (1)
- guanine nucleotide exchange factor (1)
- guttiferae (1)
- hadron hadron scattering (1)
- hadronic final state (1)
- hadronisation model (1)
- haemolymph (1)
- hardwood dust (1)
- harmonia axyridis (1)
- harmonine (1)
- head involution (1)
- health-related quality of life (1)
- hearing loss (1)
- heart (1)
- heart development (1)
- heart-rate-variability (1)
- heartbeat perception (1)
- heat shock protein Hsc-70 (1)
- heavy flavour (1)
- heavy flavour quark (1)
- heavy neutrino (1)
- helicase BRIP1 (1)
- helicity fraction (1)
- helper T cells (1)
- hemagglutinin (1)
- hemicraniectomy (1)
- hemodialysis (1)
- hemophilus influenzae (1)
- hepatotoxicity (1)
- herbivore-parasitoid interaction (1)
- hereditary motor and sensory neuropathy (1)
- heritability (1)
- hernia defect (1)
- hernia repair material (1)
- heterostructures (1)
- hexanucleotide repeat (1)
- hierarchy (1)
- high jet multiplicity (1)
- high-dose atorvastatin (1)
- high-resolution analysis (1)
- high-temperature NMR (1)
- higher pitch (1)
- highland malaria (1)
- highlands (1)
- hindbrain boundary (1)
- hippocampal neurogenesis (1)
- histidine kinase (1)
- homeostasis (1)
- homology modeling (1)
- honey bee (1)
- honey bees (1)
- honeybees (1)
- hormone flow modelling (1)
- hormone-related protein (1)
- host cell death (1)
- host genetics (1)
- human (1)
- human cancer diseases (1)
- human diseases (1)
- human endothelial cells (1)
- human exposure (1)
- human factor H (1)
- human genetics (1)
- human jagged1 (1)
- human keratinocytes (1)
- human monocytes (1)
- human parthenogenetic neural stem cells (1)
- human parthenogenetic stem cells (1)
- human pathogens (1)
- humaner Faktor H (1)
- humans (1)
- hybrid (1)
- hydatid disease (1)
- hydrodynamics (1)
- hymenoptera (1)
- hyper-IL-6 (1)
- hyperekplexia (1)
- hypertension (1)
- idiotype (1)
- imaging genetics (1)
- immortalization (1)
- immune response (1)
- immune suppression (1)
- immune-response (1)
- immunity (1)
- immunization (1)
- immunoglobulin-G (1)
- immunohistochemistry (1)
- immunology (1)
- immunosenescence (1)
- immunostaining (1)
- imperforate anus (1)
- imprinting. (1)
- in situ guided tissue regeneration (1)
- in vitro cell culture models (1)
- in vitro neural differentiation (1)
- in vivo imaging (1)
- in-vitro fertilization (1)
- in-vitro propagation (1)
- in-vivo (1)
- inactivation (1)
- incisional abdominal wall hernia (1)
- incisional hernia (1)
- inclusive cross section (1)
- inclusive jet sample (1)
- individual systematic uncertainty (1)
- individual-based simulation (1)
- induction (1)
- infants born (1)
- infected bee (1)
- infection (1)
- infiltrate (1)
- inflammatory cytokines (1)
- inflammatory mechanisms (1)
- influenza (1)
- information (1)
- ingle-molecule microscopy (1)
- inguinal hernia (1)
- inhibitory synapse (1)
- inos (1)
- insecticides (1)
- instrument (1)
- insulin pathway (1)
- insulin receptor (1)
- integration (1)
- intensity-modulated radiotherapy (1)
- intent (1)
- intentional binding (1)
- interacting species (1)
- interaction (1)
- interaktive Arten (1)
- interferon gamma (1)
- interferon-gamma (1)
- interleukin 6 (1)
- interleukin-1 receptor antagonist (1)
- interleukin-6-type cytokines (1)
- internal fixation (1)
- internal transcribed spacer 2 (1)
- internalization studies (1)
- intervention (1)
- intraarticular fractures (1)
- intracellular pathogen (1)
- intractable hiccup (1)
- intramolecular Michael addition (1)
- intravenous glucose tolerance test (1)
- invadopodia (1)
- invariant mass (1)
- invariant mass distribution (1)
- invariant mass resolution (1)
- investigators (1)
- iodine contrast (1)
- ionizing radiation (1)
- iron oxide nanoparticles (1)
- iron-pnictides (1)
- ischaemic stroke (1)
- ischemia (1)
- ischemia-reperfusion injury (1)
- ischemic cascade (1)
- ischemic stroke (1)
- isolation requirement (1)
- isthmic oragnizer (1)
- italian population (1)
- jet axis (1)
- jet background (1)
- jet calibration (1)
- jet cross section (1)
- jet energy (1)
- jet energy measurement (1)
- jet multiplicity (1)
- jet response (1)
- jet sample (1)
- jet scale energy (1)
- judgements (1)
- kidney (1)
- kingdom (1)
- kinin receptors (1)
- knock-out mice (1)
- knock-out mouse (1)
- knockout mice (1)
- knockout-mice (1)
- kubisch-monokliner Phasenübergang (1)
- label-free analysis (1)
- lacking (1)
- laminopathies (1)
- land (1)
- land use (1)
- landscape (1)
- large rapidity gap (1)
- larva (1)
- laser suture lysis (1)
- learning performances (1)
- legionella pneumophila (1)
- lepton flavour (1)
- leptonic final state (1)
- lesion formation (1)
- lesion size (1)
- leukemia-inhibitory factor (1)
- leukocyte adhesion (1)
- life events (1)
- life style (1)
- life-span regulation (1)
- light avoidance (1)
- lineage (1)
- linear trend analysis (1)
- lipid-lowering therapy (1)
- liver (1)
- livingstonei (1)
- local translation (1)
- locomotor activity (1)
- locus coeruleus (1)
- logistic regression modeling (1)
- lokale Proteinsynthese (1)
- long-term reuse (1)
- long-term-memory (1)
- low molecular weight (1)
- lower limit of normal (1)
- lower reaches of Amu Darya River (1)
- mRNA processing (1)
- macrophage (1)
- macrophages (1)
- macular degeneration (1)
- maculopathy (1)
- magnetic resonsance imaging (1)
- magnetic-resonance-spectroscopy (1)
- major depression (1)
- majorana bound states (1)
- malaria model (1)
- malaria projection (1)
- male bees (1)
- malignant MCA infarct (1)
- malignant glaucoma (1)
- malignant pleural mesothelioma (1)
- mammalian CRY1 (1)
- mammalian cells (1)
- mammographic density (1)
- mapping function (1)
- marathon running (1)
- marine sponge (1)
- markers (1)
- masked priming (1)
- mass spectometry (1)
- mast cells (1)
- matrix metalloproteinase (1)
- matrix metalloproteinases (1)
- maxillary sinus (1)
- mean σ(C–C) = 0.003 Å (1)
- mean σ(C–C) = 0.004 Å (1)
- measles virus (1)
- mechanism (1)
- mechanismofaction (1)
- medaka (1)
- media communication (1)
- mediated apoptosis (1)
- medicine (1)
- megavoltage computed-tomography (1)
- melatonin (1)
- memory (1)
- memory suppression (1)
- meningococcal disease (1)
- mesenchymal cells (1)
- mesenchymal stem cells (1)
- mesenchymal tissues (1)
- mesenchymale Stammzellen (1)
- mesh augmentation (1)
- mesh repair (1)
- metabolic flux (1)
- metabolism (1)
- metacestode vesicles (1)
- metagenomics (1)
- metal-to-insulator transition (1)
- metallurgical characterization (1)
- methane emissions (1)
- methanol methyltransferase isozymes (1)
- methanosarcina mazei GO1 (1)
- methicillin (1)
- method development (1)
- methyl-bromide (1)
- methylation (1)
- methylene blue (1)
- methylphenidate (1)
- miR-22 (1)
- miR-26b (1)
- miRNA (1)
- miRNS (1)
- mices (1)
- microRNA (1)
- microRNAs (1)
- microangiopathy (1)
- microarray (1)
- microarrays (1)
- microdeletion (1)
- microdomains (1)
- micronucleus assay (1)
- microscopy (1)
- microvascular density (1)
- microvascular endothelial cells (1)
- microvascular endothelial-cells (1)
- microvessel permeability (1)
- mimecan (1)
- mimicry (1)
- minimal inhibitory concentration (1)
- mirrorneuronsystem (1)
- mismatch negativity mmn (1)
- mitochondria (1)
- mitochondrial dysfunction (1)
- modelo PBPK/PBTK (1)
- models (1)
- modules (1)
- molecular epidemiology (1)
- molecular genetics (1)
- molecular systematics (1)
- molecular transport (1)
- molybdenum (1)
- molybdenum cofactor biosynthesis (1)
- momentum scale (1)
- monoamine transporters (1)
- monoclonal antibody (1)
- monocycline (1)
- monolayer graphite (1)
- mononuclear phagocytes (1)
- monozygotic twins (1)
- morphogenetic protein (1)
- moth manduca sexta (1)
- motility (1)
- motoneurons (1)
- motor function (1)
- motor neuron (1)
- motor preparation (1)
- motor-neuron protein (1)
- mouse (1)
- mouse model (1)
- movement ecology (1)
- movements (1)
- mulitple-sclerosis patients (1)
- multi-band superconductivity (1)
- multi-wavelength (1)
- multicenter (1)
- multicomponent Ugi-type reaction (1)
- multifactorial (1)
- multiflora (1)
- multijet event (1)
- multilocularis (1)
- multiparticle collision dynamics (1)
- multiple myeloma (1)
- multiple system atrophy (1)
- multiple-sclerosis (1)
- muon (1)
- muon decay channel (1)
- muon reconstruction efficiency (1)
- muon spectrometer (1)
- murine leishmaniasis (1)
- muscle force (1)
- mushroom bodies (1)
- music (1)
- mutagenicity (1)
- mutant mice (1)
- myasthenia gravis (1)
- mycobacterium-tuberculosis (1)
- mycotoxin (1)
- myelination (1)
- myeloid derived suppressor cells (1)
- myoelectric activity (1)
- myosin-VI (1)
- nano (1)
- nanoelectromechanical systems (1)
- nanographenes (1)
- nanowires (1)
- nasal cancer (1)
- nasal lavage (1)
- nasal snuff (1)
- nasal spray (1)
- nasopharyngeal carcinoma (1)
- nasopharyngeal colonization (1)
- natural history (1)
- necrosis-factor-alpha (1)
- neisseria gonorrhoeae (1)
- neisseria meningitidis (1)
- neobellieria bullata (1)
- neonates (1)
- nephrotoxicity (1)
- nervour system (1)
- nervous system (1)
- nervous-system (1)
- netcar-feeding bats (1)
- neural apoptosis (1)
- neural crest (1)
- neurite outgrowth (1)
- neurobehavioural deficits (1)
- neuroinflammation (1)
- neuronal differentiation (1)
- neuronale Differenzierung (1)
- neurons form (1)
- neuropathy (1)
- neuropsychology (1)
- neurorepair (1)
- neuroscience (1)
- neurothrophic factor (1)
- neurovirulence (1)
- neutral Higgs boson (1)
- neutral currents (1)
- neutral loss (1)
- neutrophils (1)
- nichtholonomes System (1)
- nickel (1)
- nickel release (1)
- nicotine addiction (1)
- nicotinic acetylcholine-receptors (1)
- nitric oxide synthase (1)
- nitricoxidesynthase (1)
- non-convex optimal control problems (1)
- nonalcoholic steatohepatitis (1)
- noncooperative binding (1)
- nonholonomic system (1)
- noninvasive detection (1)
- nonribosomal peptide synthetase (1)
- noradrenalin (1)
- norepinephrine (1)
- novelty detection (1)
- nuclear envelope (1)
- nuclear lamina (1)
- nuclear organization (1)
- nuclear transport (1)
- nucleosome (1)
- nucleotide exchange (1)
- nucleotide excision-repair (1)
- nucleus (1)
- nude mice (1)
- numerical approximations (1)
- nutrient uptake (1)
- nutrients (1)
- nyctalus noctula (1)
- obstructive pulmonary disease (1)
- occupational exposures (1)
- odourants (1)
- oncogenes (1)
- oncolytic therapy (1)
- oncolytic virus (1)
- one-dimensional (1)
- onset (1)
- open reduction (1)
- ophrys heldreichii (1)
- optical coherence tomography (1)
- organic bulk heterojunction solar cell (1)
- organic chemistry (1)
- organic photovoltaics (1)
- organic solvents (1)
- organische Photovoltaik (1)
- organische Solarzelle (1)
- organization (1)
- organogenesis (1)
- organometal complexes (1)
- organometallic complexes (1)
- organosilicon (1)
- orthodontic brackets (1)
- oscillator (1)
- osteoblast differentiation (1)
- osteochondral allografts (1)
- osteogenesis imperfecta (1)
- osteoglycin (1)
- osteoporosis (1)
- otitis media (1)
- outer membrane protein (1)
- outer-membrane proteins (1)
- oxide (1)
- p53 (1)
- pair invariant mass (1)
- pancreatic cancer (1)
- panic disorder (1)
- panton-valentine leukocidin (1)
- paradigm (1)
- paranasal sinuses (1)
- parastomal hernia (1)
- parathyroid hormone (1)
- parathyroid-hormone (1)
- parent-child agreement (1)
- parkinson disease (1)
- pars plana vitrectomy (1)
- partial purification (1)
- particle level jet (1)
- partitioning analysis RPA (1)
- parton shower (1)
- pathogenicity island 2 (1)
- pathophysiology (1)
- pathways (1)
- pea (1)
- pediatric lymphoma (1)
- people (1)
- peptide (1)
- peptides (1)
- percutaneous fixation (1)
- performance liquid-chromatography (1)
- perfusion (1)
- period variability (1)
- persistent ADHD (1)
- persistierende Infektion (1)
- perylene bisimide (1)
- pesticides (1)
- pet (1)
- pet dogs (1)
- phagocytosis (1)
- phagosomalescape (1)
- phase variation (1)
- photocurrent (1)
- photoelectron spectroscopy (1)
- photoemission (1)
- photoinhibition (1)
- photon energy scale (1)
- photoprotection (1)
- photosystem II (1)
- phylogenetic tree (1)
- phylogeny (1)
- physical activity (1)
- physical time (1)
- pig or swine (1)
- pioglitazone (1)
- pitch (1)
- placebo-controlled (1)
- placebo-controlled trial (1)
- planning (1)
- plant-microbe interaction (1)
- plant–microbe interaction (1)
- plasma cells (1)
- plasmodium falciparum (1)
- platelet adhesion (1)
- platelets (1)
- plexus epithelial-cells (1)
- pluripotent (1)
- polarisation pulse shaping (1)
- political discourse (1)
- politischer Diskurs (1)
- pollination (1)
- polyarcylamide gels (1)
- polymavirus (1)
- polymorphism (1)
- polymorphisms (1)
- polyomavirus (1)
- population (1)
- population biology (1)
- pore formation and translocation (1)
- positron-emission-tomography (1)
- post-transcriptionalregulation (1)
- posttraumatic-stress-disorder (1)
- pp collision (1)
- pragmatics (1)
- pre-messenger RNA (1)
- predation risk (1)
- prediction (1)
- predictivetextentry (1)
- predictors (1)
- pregnancy (1)
- prenatal stress (1)
- prepulse inhibition (1)
- preterm (1)
- preterm infants (1)
- primary prevention (1)
- primary ventral hernia (1)
- primary-care physicians (1)
- printed paper photovoltaics (1)
- probes (1)
- processing deficits (1)
- producation cross section (1)
- production cross section (1)
- progenitor cells (1)
- prognostic index (1)
- prognostic relevance (1)
- prognostic value (1)
- proliferation (1)
- promoter (1)
- promoter methylation (1)
- propagation (1)
- prophylaxis (1)
- propulsion (1)
- prostate (1)
- prostate cancer (1)
- protein argentine methyltranserase (1)
- protein disulfide isomerase (1)
- protein docking (1)
- protein familiy (1)
- protein folding (1)
- protein subunit (1)
- protein synthesis (1)
- protein-interaction networks (1)
- proteins (1)
- proteinuria (1)
- proteolipid protein gene (1)
- proton (1)
- präemptiver Schlag (1)
- pränataler Stress (1)
- pseudomas-syringae (1)
- psoas muscle (1)
- psychopathology (1)
- psychosis (1)
- pulmonary embolism (1)
- pulmonary gas-exchange (1)
- pyrococcus furiosus (1)
- pythia parton shower (1)
- quali-chick chimeras (1)
- quality-of-life (1)
- quantitative trait locus (1)
- quantized vortices (1)
- quantum chemistry (1)
- quantum field theory (1)
- queueing networks (1)
- radiation oncology (1)
- radiofrequency ablation (1)
- radiotherapy (1)
- rain forest (1)
- raman spectroscopy (1)
- randomized-trial (1)
- range formation (1)
- rapidity interval (1)
- rare (1)
- rare decays (1)
- rat (1)
- rat calyx (1)
- rat heart (1)
- rat spinal-cord (1)
- reaction centre (1)
- reactivity (1)
- reading disability (1)
- real-time glucose monitoring (1)
- receptor clustering (1)
- receptor-beta subunits (1)
- receptors (1)
- recolonization (1)
- recombination (1)
- recombination hotspot (1)
- reconstructed mass spectrum (1)
- reconstruction (1)
- recurrence (1)
- recurrent abdominal wall hernia (1)
- recursive Green's functions (1)
- regenerative medicine (1)
- region (1)
- regional climate model (1)
- regionales Klimamodell (1)
- registries (1)
- registry (1)
- regulation (1)
- regulatory RNA (1)
- regulatory T cell (1)
- regulatory T cells (1)
- relative abundance (1)
- releasable suture (1)
- relevance (1)
- renal disease (1)
- renal perfusion (1)
- renewable energies (1)
- renewal (1)
- replicating adenovirus (1)
- replicative senescence (1)
- reporter gene (1)
- reproductive medicine (1)
- rescue (1)
- resonant scattering (1)
- respiratory-distress-syndrome (1)
- response inhibition (1)
- response regulator (1)
- resting tremor (1)
- restricition enzymes (1)
- resummation (1)
- resurgence (1)
- resveratrol (1)
- retinal ganglion cells (1)
- retinocochleocerebral (1)
- retroviral infection (1)
- reward (1)
- rheumatoid (1)
- rhizobacteria (1)
- rhythm (1)
- ribonuclease-P (1)
- ribonucleases (1)
- ribwort plantain (1)
- richtersius coronifer (1)
- risk (1)
- risk assessment (1)
- risk factor (1)
- risk genes (1)
- room temperature (1)
- root (1)
- rotational diffusion (1)
- rs112587690 (1)
- rs12628 (1)
- rules (1)
- rural domain (1)
- ruthenates (1)
- sDMA (1)
- sRNA (1)
- safety (1)
- safety research (1)
- salmonella enterica (1)
- salt lakes (1)
- satellite rainfall products (1)
- sationary phase (1)
- satisfiability problems (1)
- savanna woodland (1)
- scaffolding protein gephyryrin (1)
- scaffolds (1)
- scanning tunneling microscopy (1)
- scattering (1)
- scattering amplitudes (1)
- scenarios (1)
- schizosaccaromyces-pombe (1)
- scid mice (1)
- scintigraphy (1)
- screening (1)
- secondary cancer (1)
- secondary prevention (1)
- secondary structure (1)
- seed protein concentration (1)
- segmental collapse (1)
- selective attention (1)
- self-assembly (1)
- self-rating (1)
- self-trapping (1)
- semi-convex hulls (1)
- semi-konvexe Hüllen (1)
- semiconductor microavity (1)
- semiconductors (1)
- sensitization (1)
- sensor (1)
- sepsis (1)
- sequence (1)
- sequence alignment (1)
- sequence imaging protocol (1)
- sequence-structure (1)
- sequential standard model (1)
- sequestration (1)
- serogroup B (1)
- serotonin (1)
- serotonin deficiency (1)
- serotonin transporter (1)
- serotonin transporter gene (1)
- set (1)
- severe renal insufficiency (1)
- sexual deception (1)
- sexual stage surface proteins (1)
- sglt1 (1)
- sheep model (1)
- shiitake dermatitis (1)
- shiitake mushrooms (1)
- shiitake-dermatite (1)
- shock (1)
- shock sigma factor (1)
- signal peptides (1)
- signal template (1)
- signals (1)
- simulaed event sample (1)
- simulated event sample (1)
- simulation (1)
- sinonasal cancer (1)
- size (1)
- skeletal overexpression (1)
- skin (1)
- skin cancer (1)
- slow cortical potentials (1)
- small RNA (1)
- small noncoding RNAs (1)
- small nucleolar RNAs (1)
- small vessel disease (1)
- smoking (1)
- smoking habits (1)
- smoking-cessation (1)
- snRNP (1)
- social calls (1)
- social teachings (1)
- sodium (1)
- soil macrofauna (1)
- soils/sediments (1)
- solid-phase extraction (1)
- solvent (1)
- somatic mosaicism (1)
- sonic hedghog (1)
- sorbents (1)
- soybean (1)
- sparticle cascade decay (1)
- sparticle pair production (1)
- spatial attention (1)
- spatial cueing (1)
- specialization (1)
- species composition (1)
- species richness (1)
- species richness estimation (1)
- specification (1)
- spectrofluorimetry (1)
- spectroscopy (1)
- spectrum disorders (1)
- spin-orbit coupling (1)
- spinal-cord (1)
- spiroplasma (1)
- splicing factor (1)
- spontaneous mouse mutants (1)
- sporadic Parkinson's disease (1)
- sptPALM (1)
- squamous cell (1)
- stage pT1 (1)
- standard heparin (1)
- standard model (1)
- states (1)
- stationary phase (1)
- steady state (1)
- stent (1)
- still-face (1)
- stochastic processes (1)
- stochastischer Prozess (1)
- stocks (1)
- strain (1)
- strain MC58 (1)
- stranded DNAs (1)
- strategies (1)
- strategy (1)
- streptozotocin (1)
- stress perfusion (1)
- string theory (1)
- stroke therapy (1)
- stromal cells (1)
- subacute sclerosing-panencephalitis (1)
- subpopulation (1)
- subspace clustering (1)
- substantia nigra (1)
- subunit (1)
- sufficient optimality conditions (1)
- summer rainfall (1)
- sumo (1)
- sumoylation (1)
- superoxide-dismutase (1)
- superresolution (1)
- supersymmetric standard model (1)
- supersymmetry (1)
- supersymmetry phenomenology (1)
- surface analysis (1)
- surface functionalisation (1)
- surfactant (1)
- surfactant protein-A (1)
- surrogate endpoints (1)
- survivin (1)
- survivin T-cell reactivity (1)
- survivors (1)
- susceptibility (1)
- susceptibility loci (1)
- swiss model (1)
- symbiosis (1)
- symmetry breaking (1)
- symptoms (1)
- synapse formation (1)
- synaptic inhibition (1)
- synechocystis (1)
- synthesis (1)
- synthesis silicon (1)
- synthetic biology (1)
- synthetic surfactant (1)
- systematic effect (1)
- systems (1)
- tPA (1)
- tandem mass-spectrometry (1)
- tardigrada (1)
- target molecule (1)
- task force (1)
- technology (1)
- teleconnection (1)
- temperature (1)
- temperatures (1)
- temporal order judgments (1)
- temporal-lobe epilepsy (1)
- tensor rank (1)
- tergite (1)
- teriparatide (1)
- term memory (1)
- territory infaction (1)
- think/no-think paradigm (1)
- thiostrepton (1)
- thrombosis (1)
- thymus (1)
- tight junctions (1)
- time (1)
- time hole (1)
- time series (1)
- time-optimal control (1)
- tissue microarray (1)
- tissue-plasminogen activator (1)
- titanium (1)
- to-disc ratio (1)
- top event dilepton invariant mass (1)
- top physics (1)
- top quark (1)
- top quark contribution (1)
- top quark masse (1)
- topology (1)
- total pancreatectomy (1)
- total systematic uncertainty (1)
- toxicity (1)
- toxicocinética (1)
- toxicokinetics (1)
- track data analysis (1)
- track momentum (1)
- track multipilicty (1)
- tracking (1)
- traffic noise (1)
- transcription activation (1)
- transcription factor (1)
- transcription factor MIZ-1 (1)
- transcription factors (1)
- transcription-3 (STAT3) (1)
- transcriptional regulator (1)
- transcriptome (1)
- transcriptomeanalysis (1)
- transcutaneous (1)
- transduction (1)
- transgenic mouse model (1)
- transient absorption spectroscopy (1)
- transient ischemic attack (1)
- transiente Absorptionsspektroskopie (1)
- transistors (1)
- transitional cell carcinoma (1)
- translation (1)
- translational initiation (1)
- translational research (1)
- translocation (1)
- transmission blocking vaccine (1)
- transverse momentum momentum spectrum (1)
- transverse momentum vector (1)
- transverse plane (1)
- tremor (1)
- triangular lattice (1)
- trinervitermes (1)
- tropical North-Africa (1)
- true diversity (1)
- trypanosome lytic factor (1)
- tryptophan (1)
- tube formation (1)
- tuberculous meningitis (1)
- tumor microenvironment (1)
- tumor necrosis factor (1)
- tumor specific antigen (1)
- tumor subtypes (1)
- tumor suppressor (1)
- tumor-draining lymph node (1)
- tumor-necrosis-factor (1)
- type 2 diabetes mellitus (1)
- typification (1)
- tyrosine kinase (1)
- tyrosine phosphorylation (1)
- ultrasoft pseudopotentials (1)
- ultrasound (1)
- ultrastructure (1)
- umbilical hernia (1)
- unconscious processing (1)
- unconverted photon (1)
- underlying event tune (1)
- unfractionated heparin (1)
- univentricular heart (1)
- unpaired median neurons (1)
- up regulation (1)
- upside-down faces (1)
- urothelial bladder carcinoma (1)
- user-centered (1)
- utilization distributions (1)
- vaccination (1)
- vaccines (1)
- vaccinia virus replication (1)
- validation region (1)
- validity (1)
- variant genotypes (1)
- vascular dementia (1)
- vasculopathy (1)
- vav2 (1)
- ventilation (1)
- ventral hernia (1)
- ventral hernia model (1)
- ventricular tachycardia (1)
- very-long-chain aldehydes (1)
- vibrio cholerae (1)
- vicinal surfaces (1)
- viral therapy (1)
- virotherapy (1)
- virtual reality (1)
- virus-induced encephalitis (1)
- visceral leishmaniasis (1)
- viscosity (1)
- visual-evoked potentials (1)
- vitamin C (1)
- vitamin-D-receptor (1)
- vitellogenin (1)
- vivo (1)
- voltage dependent (1)
- volume determination (1)
- von Willebrand factor (1)
- voxel-based morphometry (1)
- wR factor = 0.038 (1)
- wR factor = 0.052 (1)
- waking states (1)
- walking (1)
- water channels (1)
- water load test (1)
- water stress (1)
- wax (1)
- well (1)
- whole-brain radiotherapy (1)
- wires (1)
- women (1)
- wood dust (1)
- work bee (1)
- workbench (1)
- worker bee larva (1)
- young work bee (1)
- zeitoptimale Steuerung (1)
- zweiachsgelenkter Roboter (1)
- Ähnlichkeit (1)
- Übergangsmetallkomplexe (1)
- Übergangszustand (1)
- β-APP (1)
- “basic emotion” (1)
Institute
- Theodor-Boveri-Institut für Biowissenschaften (83)
- Fakultät für Physik und Astronomie (38)
- Graduate School of Life Sciences (32)
- Institut für Psychologie (25)
- Neurologische Klinik und Poliklinik (24)
- Institut für Molekulare Infektionsbiologie (23)
- Klinik und Poliklinik für Psychiatrie, Psychosomatik und Psychotherapie (21)
- Physikalisches Institut (19)
- Rudolf-Virchow-Zentrum (16)
- Lehrstuhl für Biochemie (15)
Sonstige beteiligte Institutionen
A general theory for all classes of unconventional superconductors is still one of the unsolved key issues in condensed-matter physics. Actually, it is not yet fully settled if there is a common underlying pairing mechanism. Instead, it might be possible that several distinct sources for unconventional (not phonon-mediated) superconductivity have to be considered, or an electron-phonon interaction is not negligible. The focus of this thesis is on the most probable mechanism for the formation of Cooper pairs in unconventional superconductors, namely a strictly electronic one where spin fluctuations are the mediators. Studying different superconductors in this thesis, the emphasis is put on material-independent features of the pairing mechanism. In addition, the investigation of the phase diagrams enables a view on the vicinity of superconductivity. Thus, it is possible to clarify which competing quantum fluctuations enhance or weaken the propensity for a superconducting state. The broad range of superconducting materials requires the use of more than one numerical technique to study an appropriate microscopic description. This is not a problem but a big advantage because this facilitates the approach-independent description of common underlying physics. For this evaluation, the strongly correlated cuprates are simulated with the variational cluster approach. Especially the question of a pairing glue is taken into consideration. Furthermore, it is possible to distinguish between retarded and non-retarded contributions to the gap function. The cuprates are confronted with the cobaltate NaCoO and graphene. These weakly correlated materials are investigated with the functional renormalization group (fRG) and reveal a comprehensive phase diagram, including a d+id-wave superconductivity, which breaks time-reversal symmetry. The corresponding gap function is nodeless, but for NaCoO, it features a doping-dependent anisotropy. In addition, some general considerations on the kagome lattice are completing the discussion, where a sublattice interference dramatically affects the Fermi-surface instabilities, suppressing the usual spin-density wave and d+id-wave superconductivity. Thereby, some different fascinating charge and bond orders as well as a nematic are observable. In short, this thesis provides an insight to distinct classes of unconventional superconductors with appropriate simulation techniques. This facilitates to separate the material specific properties from the universal ones.
U.S. and German Approaches to Regulating Retail Development: Urban Planning Tools and Local Policies
(2012)
This dissertation examines retail development regulation in the U.S. and in Germany, comparing the various urban planning tools and policies in use by municipal governments. These similarities and differences are explored through research into three case study cities in each country, with special attention paid to how these governments regulate large-scale or "big box" retail.
Two-Dimensional Electron Systems at Surfaces — Spin-Orbit Interaction and Electronic Correlations
(2012)
This thesis addresses three different realizations of a truly two-dimensional electron system (2DES), established at the surface of elemental semiconductors, i.e., Pt/Si(111), Au/Ge(111), and Sn/Si(111). Characteristic features of atomic structures at surfaces have been studied using scanning tunneling microscopy and low energy electron diffraction with special emphasis on Pt deposition onto Si(111). Topographic inspection reveals that Pt atoms agglomerate as trimers, which represent the structural building block of phase-slip domains. Surprisingly, each trimer is rotated by 30° with respect to the substrate, which results in an unexpected symmetry breaking. In turn, this represents a unique example of a chiral structure at a semiconductor surface, and marks Pt/Si(111) as a promising candidate for catalytic processes at the atomic scale. Spin-orbit interactions (SOIs) play a significant role at surfaces involving heavy adatoms. As a result, a lift of the spin degeneracy in the electronic states, termed as Rashba effect, may be observed. A candidate system to exhibit such physics is Au/Ge(111). Its large hexagonal Fermi sheet is suggested to be spin-split by calculations within the density functional theory. Experimental clarification is obtained by exploiting the unique capabilities of three-dimensional spin detection in spin- and angle-resolved photoelectron spectroscopy. Besides verification of the spin splitting, the in-plane components of the spin are shown to possess helical character, while also a prominent rotation out of this plane is observed along straight sections of the Fermi surface. Surprisingly and for the first time in a 2DES, additional in-plane rotations of the spin are revealed close to high symmetry directions. This complex spin pattern must originate from crystalline anisotropies, and it is best described by augmenting the original Rashba model with higher order Dresselhaus-like SOI terms. The alternative use of group-IV adatoms at a significantly reduced coverage drastically changes the basic properties of a 2DES. Electron localization is strongly enhanced, and the ground state characteristics will be dominated by correlation effects then. Sn/Si(111) is scrutinized with this regard. It serves as an ideal realization of a triangular lattice, that inherently suffers from spin frustration. Consequently, long-range magnetic order is prohibited, and the ground state is assumed to be either a spiral antiferromagnetic (AFM) insulator or a spin liquid. Here, the single-particle spectral function is utilized as a fundamental quantity to address the complex interplay of geometric frustration and electronic correlations. In particular, this is achieved by combining the complementary strengths of ab initio local density approximation (LDA) calculations, state-of-the-art angle-resolved photoelectron spectroscopy, and the sophisticated many-body LDA+DCA. In this way, the evolution of a shadow band and a band backfolding incompatible with a spiral AFM order are unveiled. Moreover, beyond nearest-neighbor hopping processes are crucial here, and the spectral features must be attributed to a collinear AFM ground state, contrary to common expectation for a frustrated spin lattice.
Background
Animal models are frequently used to assess new treatment methods in cancer research. MRI offers a non-invasive in vivo monitoring of tumour tissue and thus allows longitudinal measurements of treatment effects, without the need for large cohorts of animals. Tumour size is an important biomarker of the disease development, but to our knowledge, MRI based size measurements have not yet been verified for small tumours (10−2–10−1 g). The aim of this study was to assess the accuracy of MRI based tumour size measurements of small tumours on mice.
Methods
2D and 3D T2-weighted RARE images of tumour bearing mice were acquired in vivo using a 7 T dedicated animal MR system. For the 3D images the acquired image resolution was varied. The images were exported to a PC workstation where the tumour mass was determined assuming a density of 1 g/cm3, using an in-house developed tool for segmentation and delineation. The resulting data were compared to the weight of the resected tumours after sacrifice of the animal using regression analysis.
Results
Strong correlations were demonstrated between MRI- and necropsy determined masses. In general, 3D acquisition was not a prerequisite for high accuracy. However, it was slightly more accurate than 2D when small (<0.2 g) tumours were assessed for inter- and intraobserver variation. In 3D images, the voxel sizes could be increased from 1603 μm3 to 2403 μm3 without affecting the results significantly, thus reducing acquisition time substantially.
Conclusions
2D MRI was sufficient for accurate tumour size measurement, except for small tumours (<0.2 g) where 3D acquisition was necessary to reduce interobserver variation. Acquisition times between 15 and 50 minutes, depending on tumour size, were sufficient for accurate tumour volume measurement. Hence, it is possible to include further MR investigations of the tumour, such as tissue perfusion, diffusion or metabolic composition in the same MR session.
Background: To evaluate oncological and clinical outcome in patients with renal cell carcinoma (RCC) and tumor thrombus involving inferior vena cava (IVC) treated with nephrectomy and thrombectomy. Methods: We identified 50 patients with a median age of 65 years, who underwent radical surgical treatment for RCC and tumor thrombus of the IVC between 1997 and 2010. The charts were reviewed for pathological and surgical parameters, as well as complications and oncological outcome. Results: The median follow-up was 26 months. In 21 patients (42%) distant metastases were already present at the time of surgery. All patients underwent radical nephrectomy, thrombectomy and lymph node dissection through a flank (15 patients/30%), thoracoabdominal (14 patients/28%) or midline abdominal approach (21 patients/42%), depending upon surgeon preference and upon the characteristics of tumor and associated thrombus. Extracorporal circulation with cardiopulmonary bypass (CPB) was performed in 10 patients (20%) with supradiaphragmal thrombus of IVC. Cancer-specific survival for the whole cohort at 5 years was 33.1%. Survival for the patients without distant metastasis at 5 years was 50.7%, whereas survival rate in the metastatic group at 5 years was 7.4%. Median survival of patients with metastatic disease was 16.4 months. On multivariate analysis lymph node invasion, distant metastasis and grading were independent prognostic factors. There was no statistically significant influence of level of the tumor thrombus on survival rate. Indeed, patients with supradiaphragmal tumor thrombus (n = 10) even had a better outcome (overall survival at 5 years of 58.33%) than the entire cohort. Conclusions: An aggressive surgical approach is the most effective therapeutic option in patients with RCC and any level of tumor thrombus and offers a reasonable longterm survival. Due to good clinical and oncological outcome we prefer the use of CPB with extracorporal circulation in patients with supradiaphragmal tumor thrombus. Cytoreductive surgery appears to be beneficial for patients with metastatic disease, especially when consecutive therapy is performed. Although sample size of our study cohort is limited consistent with some other studies lymph node invasion, distant metastasis and grading seem to have prognostic value.
Trypanosome Motion Represents an Adaptation to the Crowded Environment ofthe Vertebrate Bloodstream
(2012)
Blood is a remarkable habitat: it is highly viscous, contains a dense packaging of cells and perpetually flows at velocities varying over three orders of magnitude. Only few pathogens endure the harsh physical conditions within the vertebrate bloodstream and prosper despite being constantly attacked by host antibodies. African trypanosomes are strictly extracellular blood parasites, which evade the immune response through a system of antigenic variation and incessant motility. How the flagellates actually swim in blood remains to be elucidated. Here, we show that the mode and dynamics of trypanosome locomotion are a trait of life within a crowded environment. Using high-speed fluorescence microscopy and ordered micro-pillar arrays we show that the parasites mode of motility is adapted to the density of cells in blood. Trypanosomes are pulled forward by the planar beat of the single flagellum. Hydrodynamic flow across the asymmetrically shaped cell body translates into its rotational movement. Importantly, the presence of particles with the shape, size and spacing of blood cells is required and sufficient for trypanosomes to reach maximum forward velocity. If the density of obstacles, however, is further increased to resemble collagen networks or tissue spaces, the parasites reverse their flagellar beat and consequently swim backwards, in this way avoiding getting trapped. In the absence of obstacles, this flagellar beat reversal occurs randomly resulting in irregular waveforms and apparent cell tumbling. Thus, the swimming behavior of trypanosomes is a surprising example of micro-adaptation to life at low Reynolds numbers. For a precise physical interpretation, we compare our high-resolution microscopic data to results from a simulation technique that combines the method of multi-particle collision dynamics with a triangulated surface model. The simulation produces a rotating cell body and a helical swimming path, providing a functioning simulation method for a microorganism with a complex swimming strategy
Trypanosome Motion Represents an Adaptation to the Crowded Environment of the Vertebrate Bloodstream
(2012)
Blood is a remarkable habitat: it is highly viscous, contains a dense packaging of cells and perpetually flows at velocities varying over three orders of magnitude. Only few pathogens endure the harsh physical conditions within the vertebrate bloodstream and prosper despite being constantly attacked by host antibodies. African trypanosomes are strictly extracellular blood parasites, which evade the immune response through a system of antigenic variation and incessant motility. How the flagellates actually swim in blood remains to be elucidated. Here, we show that the mode and dynamics of trypanosome locomotion are a trait of life within a crowded environment. Using high-speed fluorescence microscopy and ordered micro-pillar arrays we show that the parasites mode of motility is adapted to the density of cells in blood. Trypanosomes are pulled forward by the planar beat of the single flagellum. Hydrodynamic flow across the asymmetrically shaped cell body translates into its rotational movement. Importantly, the presence of particles with the shape, size and spacing of blood cells is required and sufficient for trypanosomes to reach maximum forward velocity. If the density of obstacles, however, is further increased to resemble collagen networks or tissue spaces, the parasites reverse their flagellar beat and consequently swim backwards, in this way avoiding getting trapped. In the absence of obstacles, this flagellar beat reversal occurs randomly resulting in irregular waveforms and apparent cell tumbling. Thus, the swimming behavior of trypanosomes is a surprising example of micro-adaptation to life at low Reynolds numbers. For a precise physical interpretation, we compare our high-resolution microscopic data to results from a simulation technique that combines the method of multi-particle collision dynamics with a triangulated surface model. The simulation produces a rotating cell body and a helical swimming path, providing a functioning simulation method for a microorganism with a complex swimming strategy.
Background: Target values for cardiovascular risk factors in patients with coronary heart disease (CHD) are stated in guidelines for the prevention of cardiovascular disease. We studied secular trends in risk factors over a 12-year period among CHD patients in the region of Munster, Germany.
Methods: The cross-sectional EUROASPIRE I, II and III surveys were performed in multiple centers across Europe. For all three, the Munster region was the participating German region. In the three periods 1995/96, 1999/2000, and 2006/07, the surveys included (respectively) 392, 402 and 457 <= 70-year-old patients with CHD in Munster who had sustained a coronary event at least 6 months earlier.
Results: The prevalence of smoking remained unchanged, with 16.8% in EUROASPIRE I and II and 18.4% in EUROASPIRE III (p=0.898). On the other hand, high blood pressure and high cholesterol both became less common across the three EUROASPIRE studies (60.7% to 69.4% to 55.3%, and 94.3% to 83.4% to 48.1%, respectively; p<0.001 for both). Obesity became more common (23.0% to 30.6% to 43.1%, p<0.001), as did treatment with antihypertensive and lipid-lowering drugs (80.4% to 88.6% to 94.3%, and 35.0% to 67.4% to 87.0%, respectively; p<0.001 for both).
Conclusion: The observed trends in cardiovascular risk factors under-score the vital need for better preventive strategies in patients with CHD.
Background
Blood-born miRNA signatures have recently been reported for various tumor diseases. Here, we compared the miRNA signature in Wilms tumor patients prior and after preoperative chemotherapy according to SIOP protocol 2001.
Results
We did not find a significant difference between miRNA signature of both groups. However both, Wilms tumor patients prior and after chemotherapy showed a miRNA signature different from healthy controls. The signature of Wilms tumor patients prior to chemotherapy showed an accuracy of 97.5% and of patients after chemotherapy an accuracy of 97.0%, each as compared to healthy controls.
Conclusion
Our results provide evidence for a blood-born Wilms tumor miRNA signature largely independent of four weeks preoperative chemotherapy treatment.