Refine
Year of publication
- 2019 (430) (remove)
Document Type
- Journal article (430) (remove)
Language
- English (430) (remove)
Keywords
- apoptosis (8)
- boron (6)
- inflammation (6)
- ischemic stroke (5)
- DNA methylation (4)
- cancer (4)
- cancer therapy (4)
- children (4)
- deep brain stimulation (4)
- infection (4)
- measles virus (4)
- multiple myeloma (4)
- sphingolipids (4)
- GABA (3)
- Meningitis (3)
- Monte-Carlo (3)
- Neisseria meningitidis (3)
- Physics (3)
- Survival (3)
- Ureaplasma parvum (3)
- Ureaplasma urealyticum (3)
- aging (3)
- blood–brain barrier (3)
- boranes (3)
- climate change (3)
- cytokines (3)
- cytotoxicity (3)
- death receptors (3)
- epigenetics (3)
- gephyrin (3)
- length of stenosis (3)
- leukemic cells (3)
- lysosome (3)
- machine learning (3)
- metagenomics (3)
- microbiome (3)
- remote sensing (3)
- stem cells (3)
- tissue engineering (3)
- virtual reality (3)
- 3D tissue model (2)
- Bees (2)
- Biomedical engineering (2)
- C-reactive protein (2)
- CXCR4 (2)
- Cancer (2)
- Candida albicans (2)
- Colonization (2)
- Constraints (2)
- Cross-Section (2)
- Cryo-EM (2)
- Decay (2)
- Exercise capacity (2)
- Expression (2)
- FKBP5 (2)
- GABAA receptors (2)
- HBMEC (2)
- HBV (2)
- HIV (2)
- Hadron colliders (2)
- HeLa cells (2)
- Imaging techniques (2)
- Impact (2)
- MSC (2)
- Metabolomics (2)
- Methylation (2)
- NHC (2)
- Neural circuits (2)
- Neurons (2)
- PIP2 (2)
- Pair Production (2)
- Parton Distributions (2)
- Parton distributions (2)
- Radiative-corrections (2)
- Reduction (2)
- S-ADAPT (2)
- Sentinel-1 (2)
- Solution-state NMR (2)
- Stem cells (2)
- TNF receptor superfamily (2)
- TNF superfamily (2)
- TNFR1 (2)
- TRAIL (2)
- Tanzania (2)
- Top-Quark (2)
- VEGF (2)
- adolescents (2)
- allometric scaling (2)
- antibody (2)
- antibody fusion proteins (2)
- artemisinin (2)
- autophagy (2)
- bacteria (2)
- blood-brain barrier (2)
- body composition (2)
- body size (2)
- cAArC (2)
- calcium phosphate cement (2)
- cardiomyopathy (2)
- carotid atherosclerosis (2)
- carotid stenosis (2)
- carotid ultrasound (2)
- caspase-8 (2)
- cell death (2)
- cell imaging (2)
- chemistry (2)
- colorectal cancer (2)
- complexes (2)
- copper (2)
- cystic fibrosis patients (2)
- degree of stenosis (2)
- dendritic cells (2)
- density functional calculations (2)
- depression (2)
- diazepam (2)
- ecology (2)
- fluorescence (2)
- genetics (2)
- genome annotation (2)
- genome assembly (2)
- geomorphology (2)
- glioblastoma multiforme (2)
- glucocorticoid receptor (2)
- healthy volunteers (2)
- immunotherapy (2)
- inhibitory neurotransmission (2)
- interleukin-8 (2)
- irradiation (2)
- knockout (2)
- magnetic resonance imaging (2)
- melt electrospinning writing (2)
- meningitis (2)
- mental health (2)
- mesencephalic locomotor region (2)
- metabolic adaptation (2)
- migration (2)
- mitochondria (2)
- mouse (2)
- multiple sclerosis (2)
- neuroinflammation (2)
- neurology (2)
- neuroprotection (2)
- oncolytic virus (2)
- outcome (2)
- p53 (2)
- pathogens (2)
- performance (2)
- photothrombotic stroke (2)
- polycyclic aromatic hydrocarbons (2)
- polymers (2)
- population pharmacokinetics (2)
- presence (2)
- psychiatric disorders (2)
- radicals (2)
- recurrence (2)
- relapse (2)
- ring-expansion reaction (2)
- risk factors (2)
- smartphone app (2)
- stroke (2)
- structure (2)
- surgery (2)
- survival (2)
- tight junction (2)
- trade-offs (2)
- two-photon excited fluorescence (2)
- ubiquitin (2)
- (classical and atypical) Werner syndrome (1)
- + (1)
- ++ (1)
- 18F-FDS (1)
- 2 Jets (1)
- 2-deoxy-2-18F-fluoro-D-sorbitol (1)
- 25-hydroxycholesterol 7 alpha-hydroxylase (1)
- 2Dimensionale Spektroskopie (1)
- 3-coordinate organoboron compounds (1)
- 3D (1)
- 3D printing (1)
- 3D remote sensing (1)
- 3 T (1)
- 4D flow (1)
- ABP1 (1)
- AHRR (1)
- ALAN (1)
- AMP-activated kinases (1)
- APRI (1)
- ARCI (1)
- ARCI EM type III (1)
- ATP generation (1)
- AUX1 (1)
- Accurate (1)
- Acids (1)
- Activation (1)
- Active disease (1)
- Acute myeloid leukemia (AML) (1)
- AdS-CFT Correspondence (1)
- Adherens junction (1)
- Adolescent (1)
- Adult (1)
- Akt/PKB (1)
- Alcohol dependence (1)
- Algorithm (1)
- Alien limb syndrome (1)
- Allogeneic transplantation (1)
- Alpine habitats (1)
- Alzheimer's disease (1)
- Anarchic limb syndrome (1)
- Andalusian varieties (1)
- Annotation (1)
- Anomalous magnetic-moment (1)
- Antarctica (1)
- Anthropocene (1)
- Antioxidants (1)
- Anxiety (1)
- Aortic arch (1)
- Apidae (1)
- Apis mellifera (1)
- Aplastic anemia (1)
- Apoptosis (1)
- Applied physics (1)
- Archaeology (1)
- Arylborylene Complexes (1)
- Ascaris lumbricoides (1)
- Aspergillus (1)
- Aspergillus fumigalus (1)
- Associative learning (1)
- Astrophysical neutrino sources (1)
- Atacama (1)
- Atmospheric muons (1)
- Atomic and molecular interactions with photons (1)
- Atrial fibrillation (1)
- Autologous hematopoietic stem cell transplantation (1)
- B cell malignancies (1)
- B cells (1)
- B,N-heterocylcles (1)
- B-B bond activation (1)
- B-MYB (1)
- B7-H1 (1)
- BAL (1)
- BCG (1)
- BMI (1)
- BRAF mutation (1)
- BRCA1 (1)
- Barrier (1)
- Behavioural ecology (1)
- Benzimidazole (1)
- Berberine (1)
- Bevacizumab (1)
- Bhabha Scattering (1)
- Binge drinking (1)
- Biomarke (1)
- Biophysics (1)
- Bipolar disorder (1)
- Bistability (1)
- Black Holes in String Theory (1)
- Black-hole (1)
- Blood (1)
- Body schema (1)
- Boson (1)
- Bosons (1)
- Brain cancer (1)
- Brain diseases (1)
- Brain endothelial cells (1)
- Branching fractions (1)
- Bronchopulmonary dysplasia (1)
- By-Light Scattering (1)
- B−H activation (1)
- C-60 fullerene (1)
- C-C coupling (1)
- C3a (1)
- C3aR (1)
- C5a (1)
- C5aR1 (1)
- C5aR2 (1)
- C60 fullerene (1)
- CAR T cells (1)
- CCI (1)
- CD274 (1)
- CD4+ T cells (1)
- CD8+ T cells (1)
- CD95 (1)
- CERN (1)
- CIDP (1)
- CMV (1)
- CO sensing (1)
- CO‐releasing molecules (CORMs) (1)
- CRH1 (1)
- CRMO (1)
- CXCL5 (1)
- CXCL8 (1)
- CXCR2 (1)
- CYP1B1 (1)
- C\(_{60}\) fullerene (1)
- Callyspongia siphonella (1)
- Cancer Cell (1)
- Cancer genetics (1)
- Capicua transcriptional repressor (1)
- Cardiac ventricles (1)
- Cardiovascular diseases (1)
- Cardiovascular risk factors (1)
- Cardiovascular risk prediction (1)
- Carotid intima-media thickness (CIMT) (1)
- Carotid segment (1)
- Carotid ultrasound (1)
- Caspase (1)
- Cell stainin (1)
- Cellular neuroscience (1)
- Central nervous system (1)
- Chambers (1)
- Characterization and analytical techniques (1)
- Chemical composition (1)
- Cherenkov underwater neutrino telescope (1)
- Children (1)
- Chile (1)
- Chili RNA Aptamer (1)
- Chlamydia trachomatis (1)
- Choice Behavior/physiology (1)
- Circinella (1)
- Circular dichroism (1)
- Clinically silent stroke (1)
- Cognitive behavior (1)
- Cognitive neuroscience (1)
- Community-acquired methicillin-resistant Staphylococcus aureus (1)
- Computational and Systems Biology (1)
- Computed axial tomography (1)
- Computer modelling (1)
- Conditioning regimen (1)
- Confocal microscopy (1)
- Conifers (1)
- Conservation (1)
- Consistent partial least squares (1)
- Corticobasal syndrome (1)
- Corticosteroids (1)
- Cosmic-rays (1)
- Couplings (1)
- CpG (1)
- Cranial sutures (1)
- Cross-section (1)
- Cushing’s disease (1)
- Cutaneous lymphoma (1)
- Cystic fibrosis (1)
- Cytochrome P 450 pathway (1)
- Cytosol (1)
- DC gate (1)
- DEM (1)
- DLS and AFM measurements (1)
- DNA damage (1)
- DNA electronic transport (1)
- DNA methyltransferases (1)
- DNA repair (1)
- DNA weight (1)
- DNA-repair (1)
- DNA-repair genes (1)
- DSB focus substructure (1)
- DSM (1)
- Dark-Matter (1)
- Dark-matter (1)
- Data acquisition (1)
- Deep Inelastic-scattering (1)
- Delbruck Scattering (1)
- Densovirus (1)
- Design (1)
- Developmental biology (1)
- Diagnosis prediction (1)
- Diagnostic medicine (1)
- Diffusion tensor imaging (1)
- Dihydroboranes (1)
- Disease severity (1)
- Dopamine (1)
- Double-Beta Decay (1)
- Doxorubicin (1)
- Drosophila (1)
- Drug discovery (1)
- Drug resistance (1)
- Dynamics (1)
- E(+)E(-) collicions (1)
- E2 conjugating enzyme (1)
- E3 ligating enzyme (1)
- EEA (1)
- ER-Stress (1)
- ERK (1)
- ERK signaling (1)
- ERK1/2 (1)
- ESAT‐6‐like secretion system (1)
- ESS (1)
- EUROASPIRE (1)
- EWAS (1)
- Earth observation (1)
- Echinococcosis (1)
- Echinococcus (1)
- Ecology (1)
- Efflux transport (1)
- Eigenvectors (1)
- Elderly (1)
- Electrical impedance tomography (1)
- Electromagnetic signals (1)
- Electron (1)
- Electroweak Measurements (1)
- Electroweak Phase-Transition (1)
- Electroweak interaction (1)
- Elissen-Palm flux (1)
- Embryonic induction (1)
- Embryos (1)
- Emergence (1)
- Endoplasmic-Reticulum Stress (1)
- Energy (1)
- Enhancer elements (1)
- Entanglement (1)
- Environmental impact (1)
- Epidemiology (1)
- Epigenetic (1)
- Epigenetic regulation (1)
- Epstein-Barr virus-induced gene 2 (1)
- Equipment (1)
- EsaA (1)
- Escherichia coli (1)
- European Spanish (1)
- European group (1)
- Event builder (1)
- Events GW150914 (1)
- Evolutionary developmental biology (1)
- Evolutionary emergence (1)
- Exercise testing (1)
- Extensions of gauge sector (1)
- Extracellular matrix (1)
- Extracellular volume (1)
- Extramedullary disease (1)
- Extreme flows (1)
- Exziton (1)
- Eye Movements/physiology (1)
- Eye development (1)
- FIB-4 (1)
- Fak regulation (1)
- Familial Beckwith-Wiedemann syndrome (1)
- FasL (1)
- Fatigue (1)
- Fats (1)
- Fear conditioning (1)
- Female (1)
- Fgf-signalling (1)
- Flavor Violation (1)
- Flowering plants (1)
- Flowers (1)
- Fludarabine (1)
- Fludarabine-treosulfan (FT) (1)
- Fluorescence spectroscopy (1)
- Forces (1)
- Forests (1)
- Fractional cover analysis (1)
- Full body ownership illusion (1)
- Fusarium (1)
- G-2 (1)
- GABAA (1)
- GAD1 (1)
- GRP78 (1)
- GSV (1)
- GVHD (1)
- Galactic sources (1)
- Gaseous detectors (1)
- Gauge bosons (1)
- Gauge-gravity correspondence (1)
- Gaussian approximation (1)
- Gene expression analysis (1)
- Gene silencing (1)
- General anaesthesia (1)
- Generation (1)
- Genome (1)
- Genomics (1)
- Genotype (1)
- Geriatric care (1)
- Geriatrics (1)
- Germany (1)
- Germline (1)
- Getz Ice Shelf (1)
- Glioblastoma (1)
- Glutathione (1)
- Google Earth Engine (1)
- Gravitons (1)
- Greenland ice sheet (1)
- Group B Streptococcus (1)
- Gruppo-italiano (1)
- H-infinity (1)
- HCV (1)
- HDAC (1)
- HEMA (1)
- HNSCC (1)
- HPA axis (1)
- HRQOL (1)
- Hadron-Hadron scattering (experiments) (1)
- Hadron-hadron interactions (1)
- Haemophilus influenzae (1)
- Health (1)
- Heart (1)
- Heart failure (1)
- Hematopoietic Stem (1)
- Hematopoietic cell transplant (1)
- Heme-regulated inhibitor (1)
- Hemipelvectomy (1)
- Hfq (1)
- Higgy-Boson (1)
- High grade glioma (1)
- High-Energies (1)
- Hindbrain (1)
- Histone deacetylase (1)
- Hodgkin lymphoma (1)
- Honey bees (1)
- Hordeum vulgare (1)
- Host-parasite interaction (1)
- Human Muse Cells (1)
- Human behaviour (1)
- Humans (1)
- Hunsrueck (1)
- Hyperosmotic Stress (1)
- Hypothalamus (1)
- Hypothetical gauge bosons (1)
- IFN (1)
- IL-10 (1)
- IP3 (1)
- Icecube (1)
- Immune system (1)
- Immune-related adverse event (1)
- Immunology (1)
- Immunoprecipitation (1)
- Impella (1)
- Implicit and explicit reward learning (1)
- InSAR (1)
- InSAR height (1)
- Incontinentia pigmenti (1)
- Induced apoptosis (1)
- Inducible Clindamycin Resistance (1)
- Infectious disease (1)
- Inflammatio (1)
- Inflammatory diseases (1)
- Insect flight (1)
- Interleukin-10 (1)
- Interleukin-6 (1)
- Ipilimumab (1)
- Ischemic stroke (1)
- JAK2 (1)
- KDELR2 (1)
- KIF (1)
- KIF11 (1)
- KM3NeT (1)
- Kilombero (1)
- Knee (1)
- LATE DEATHS (1)
- LC-HRESIMS (1)
- LHC (1)
- LSD1 (1)
- LST (1)
- Land Change Modeler (1)
- Landsat time series (1)
- Lantana camara (1)
- Laparoscopy (1)
- Large Hadron Collider (1)
- Late mortality (1)
- Latin America (1)
- Learning and memory (1)
- Learning/physiology (1)
- Leptonic (1)
- Lichtheimia (1)
- Lifetime spectroscopy (1)
- Limb development (1)
- Limb salvage (1)
- Limestone (1)
- Llullaillaco Volcano (1)
- Low risk alcohol use (1)
- Lung disease, (1)
- Lymph nodes (1)
- Lysine-specific methylase (1)
- M14 carboxypeptidasses (1)
- MASS (1)
- MCP1 (1)
- MDSC (1)
- MGMT promoter methylation (1)
- MIBG (1)
- MLST (1)
- MODIS (1)
- MOLLI (1)
- MRI spectroscopy (1)
- Maculinea butterfly (1)
- Magnetic resonance imaging (1)
- Male (1)
- Manganese Carbonyl ligands (1)
- Masticatory mucosa (1)
- Mastoid process (1)
- Matter (1)
- Mc4r (1)
- Measurement error correlation (1)
- Meat (1)
- Mechanisms (1)
- Medical research (1)
- Melanoma (1)
- Memory B cells (1)
- Mesenchymal stem/stromal cells (1)
- Messenger-RNAs (1)
- Methicillin-resistant Staphylococcus aureus (1)
- Mfn2 KO mice (1)
- Microbiology and Infectious Disease (1)
- Midollo-Osseo (1)
- Migration (1)
- Minimal change disease (1)
- Minimally invasive surgery (1)
- Missing Energy (1)
- Mitochondria (1)
- Mobile genetic element (1)
- Model specification (1)
- Monte Carlo simulation (1)
- Motor behaviour (1)
- Mouse (1)
- Movement behavior (1)
- Mucor (1)
- Mucorales (1)
- Multiple (1)
- Multiple myeloma (1)
- Multiple-Scattering (1)
- Multiplex PCR (1)
- Muon spectrometers (1)
- Muscle function (1)
- Muscle power (1)
- Myb-MuvB (1)
- Myrmica ant non-equilibrium dynamics (1)
- N-heterocyclic olefins (1)
- NAFLD (1)
- NASH (1)
- NCH93 (1)
- NCI-H295R (1)
- NF-Kappa-B (1)
- NF-κB/NFAT reporter cells (1)
- NFκB (1)
- NHCs (1)
- NH\(_{3}\) (1)
- NIPAL4 (1)
- NIR OLED (1)
- NLO Computations (1)
- Nanoparticles (1)
- Nasal Carriage (1)
- Necrotizing enterocolitis (1)
- Nectin‐2 (1)
- Neisseria gonorrhoeae (1)
- Neolithic period (1)
- Netherlands (1)
- Neural Differentiation (1)
- Neuroinflammation (1)
- Neuroscience (1)
- Neutrino Detectors and Telescopes (experiments) (1)
- Neutrino Mass (1)
- Nfatc1 (1)
- Nivolumab (1)
- Nonlinear Dynamics (1)
- Non‐ischaemic cardiogenic shock (1)
- Nursing homes (1)
- OSCC (1)
- OSI (1)
- Object recognition (1)
- Oculomotor Muscles/physiology (1)
- Oncology (1)
- Optical spectroscopy (1)
- Oral anticoagulation (1)
- Oscillation (1)
- Outer membrane proteins (1)
- P(P) over-bar collisions (1)
- P-glycoprotein (1)
- P-gp (1)
- PA-flexed view (1)
- PALS (1)
- PCR (1)
- PD-1 (1)
- PD-L1 (1)
- PET/CT (1)
- PP collisions (1)
- PTEN (1)
- Parkinson’s disease (1)
- Particle accelerators (1)
- Particle tracking detectors (Gaseous detectors) (1)
- Particle-acceleration (1)
- Parvovirus (1)
- Pathogenesis (1)
- Pathogens (1)
- Pavlovian-to-instrumental transfer (1)
- Pentixafor (1)
- Personalized medicine (1)
- Pflanzen (1)
- Phase- (1)
- Phenols (1)
- Phosphorylation (1)
- Photic (1)
- Physical activity (1)
- Plant signalling (1)
- Plants (1)
- Polygonum cuspidatum (1)
- Polymer-drug interaction (1)
- Polymers (1)
- Poplars (1)
- Positron annihilation spectroscopy (1)
- Positron-Emission Tomography (1)
- Positronen-Emissions-Tomografie (1)
- Postoperative complications (1)
- Premna (1)
- Preterm birth (1)
- Prevalence (1)
- ProQ (1)
- Prognostic markers (1)
- Prognostic scoring system (1)
- Protein (1)
- Protein folding (1)
- Protein kinase D3 (PKD3) (1)
- Proteus vulgaris (1)
- Proton-Proton Collisions (1)
- Psychiatric disorders (1)
- Psychology (1)
- Psychomotor Performance/physiology (1)
- Pulmonary function tests (1)
- Quality-control (1)
- Quantum electrodynamics (1)
- R package (1)
- RCT (1)
- RNA expression (1)
- RNA metabolism (1)
- RNA-seq (1)
- RNA-seq transcriptome (1)
- RNAi (1)
- RNAlater (1)
- ROR1 (1)
- RSV-A ON1 (1)
- RT-qPCR (1)
- Radiation (1)
- Radiation exposure (1)
- Radiographs (1)
- Radiotherapy (1)
- RapidEye (1)
- Regimes (1)
- Relativistic heavy-ion collisions (1)
- Reminder e-mails (1)
- Remnant RX J1713.7-3946 (1)
- Research Article (1)
- Respiratory tract infection (1)
- Retinopathy (1)
- Rhizomucor (1)
- Rhizopus (1)
- Robotics (1)
- Ruthenium (1)
- Ruxolitinib (1)
- S. aureus (1)
- SASHA (1)
- SB332235 (1)
- SPOT-6 (1)
- SR/mitochondria metabolic feedback (1)
- ST 772 (1)
- ST18 (1)
- SWAT (1)
- SWAT model (1)
- Saccades/physiology (1)
- Salmo trutta fario (1)
- Scarabaeidae (1)
- Scattering (1)
- Scenario analysis (1)
- Screening (1)
- Secondary stroke prevention (1)
- Sediment (1)
- Self-navigation (1)
- Self-renewal (1)
- Sentinel-2 (1)
- Serine proteases (1)
- Serotonin (1)
- Sex chromosome (1)
- Sex determination (1)
- Sexual development and function (1)
- ShMOLLI (1)
- Shell (1)
- Sibling donor (MSD) (1)
- Silver (1)
- Simulation (1)
- Single Molecule Localization Microscopy (SMLM) (1)
- Single-Photon (1)
- Skin (1)
- Skull (1)
- Small interfering RNAs (1)
- Smoking (1)
- Societe Francaise (1)
- Soft tissues (1)
- Solid tumors (1)
- Somites (1)
- Species delimitation (1)
- Specimen grinding (1)
- Spektroskopie (1)
- Staphylococcus aureus (1)
- Staphylococcus aureus USA300 (1)
- Stem cell (1)
- Stem-cell biotechnology (1)
- Stereochemistry (1)
- Stimulation (1)
- Stokes-shifted fluorescence emission (1)
- Strains (1)
- Strange Baryon Production (1)
- Stratigraphy (1)
- Streptococcus agalactiae (1)
- Stroke unit (1)
- Stromal cells (1)
- Structural equation modelling (1)
- Structure elucidation (1)
- Subject (1)
- Subtercola vilae (1)
- Supernova (1)
- Support vector machine (1)
- Supportive therapy (1)
- Surgical and invasive medical procedures (1)
- Surgical oncology (1)
- Survey (1)
- Swine (1)
- Syap1 knockout (1)
- Symmetry (1)
- Systemic sclerosis (1)
- T cell (1)
- T cell receptor (1)
- T cell suppression (1)
- T cells (1)
- T-cell lymphoma (1)
- T1 mapping (1)
- TDDFT (1)
- TDMT (1)
- TEV (1)
- TGFβ/BMP signaling (1)
- TLR2 (1)
- TLR4 (1)
- TNF (1)
- TNF-alpha (1)
- TNFR family costimulatory receptors (1)
- TNFR2 (1)
- TNFR2 agonists (1)
- TNFR2 antagonism (1)
- TNFα (1)
- TNNI3 (1)
- TP53 (1)
- TPCA1 (1)
- TRAF1 (1)
- TRAF2 (1)
- TRAILR1 (1)
- TRAILR2 (1)
- TanDEM-X (1)
- TeV energies (1)
- Temozolomide (1)
- Terramechanics (1)
- Thiotepa-busulfan-fludarabine (TBF) (1)
- Time resolved measurements (1)
- Toddler (1)
- Top quark (1)
- Torque (1)
- Tractography (1)
- Transcription (1)
- Transcription factor NRF1 (1)
- Transcriptomic (1)
- Translation (1)
- Translation Initiation (1)
- Translational research (1)
- Transposable element (1)
- Transverse-Momentum (1)
- Trees (1)
- Tregs (regulatory T cells) (1)
- Triticeae (1)
- Triticum aestivum (1)
- Trousseau's syndrome (1)
- Tubulin (1)
- U-Net (1)
- UV/Vis spectroscopy (1)
- UV–Vis (1)
- Ultrarelativistic Heavy-Ion (1)
- Unrelated donor (UD) (1)
- Ustilago maydis (1)
- V-ATPase (1)
- VLBW (1)
- VMAT (1)
- Valentine Leukocidin Genes (1)
- Valgus osteoarthritis (1)
- Value at Risk (1)
- Vcsels (1)
- View (1)
- Visuo-tactile congruency (1)
- W & Z bosons (1)
- WSS (1)
- Weak-Interactions (1)
- Wheel (1)
- Wire chambers (MWPC, Thin-gap chambers, drift chambers, drift tubes, proportional chambers etc) (1)
- X-ray radiography (1)
- YAP (1)
- Yoga (1)
- Young Adult (1)
- Zebrafish (1)
- Zinc (1)
- ZnO-NP (1)
- [68Ga]Pentixafor (1)
- \(^{177}\)Lu-OPS201 (1)
- abdominal surgery (1)
- absolute bioavailability (1)
- accidents (1)
- accumulation (1)
- accuracy (1)
- acetate (1)
- acid ceramidase (1)
- acid ceramidase inhibitor ceranib-2 (1)
- acoustic radiation force impulse imaging (1)
- acrophobia (1)
- actin (1)
- action control (1)
- activated delayes flourescence (1)
- activation (1)
- active galactic nuclei (1)
- active ingredients (1)
- acute kidney injury (1)
- acute lymphoblastic leukemia (1)
- additive manufacturing (1)
- adenoma (1)
- adenotonsillectromy (1)
- adiposity (1)
- adrenocortical carcinoma (1)
- adult attention deficit/hyperactivity disorder (adult ADHD) (1)
- advanced breast cancer (1)
- aerobic fitness (1)
- affect bursts (1)
- age at onset (1)
- age groups (1)
- age-related macular degeneration (1)
- agriculture (1)
- airway management (1)
- alternative splicing (1)
- altitudinal gradients (1)
- alveolar epithelium (1)
- amphiphilic block copolymer (1)
- amsacrine (1)
- amyloidoma (1)
- amyotrophic lateral sclerosis (1)
- amyotrophic lateral sclerosis (ALS) (1)
- analysis of variance (1)
- anime (1)
- anomaly detection (1)
- anorexia nervosa (1)
- anti-contactin-1 (1)
- anti-depressant drug (1)
- antibacterial (1)
- antibacterial activity (1)
- antibiofilm (1)
- antibiotic resistance (1)
- anticancer (1)
- antifungal (1)
- antitrypanosomal (1)
- anti‐aging (1)
- anxiety generalization (1)
- anxiolytics (1)
- aortocaval fistula model (1)
- appraisal theory of emotion expression (1)
- arctic greening (1)
- arenes (1)
- artificial intelligence (1)
- artificial light at night (1)
- aspergillosis (1)
- asylum seekers (1)
- asylum status (1)
- atmospheric waves (1)
- atrial fibrillation (1)
- auto-planning (1)
- autoantibody (1)
- autobiography (1)
- auxin (1)
- axillary dissection (1)
- bacterial pathogen (1)
- bacterial physiology (1)
- bacteriology (1)
- baghdadite (1)
- balancing trade-offs (1)
- bank mergers (1)
- bariatric surgery (1)
- behavior (1)
- behavioral plasticity (1)
- bench press (1)
- bending strength (1)
- benige tumor (1)
- beta-lactam antibiotics (1)
- biceps tendinitis (1)
- biceps tendon (1)
- big earth data (1)
- bilateral internal carotid artery stenosis (1)
- binary species (1)
- biofabricated vascular graft (1)
- bioinformatics tool (1)
- bioink (1)
- biokinetics (1)
- biological rhythm (1)
- biomarker (1)
- biomarker signature (1)
- biomaterial ink (1)
- biomechanics (1)
- biomolecular processes (1)
- biotic interaction (1)
- bispecific antobodies (1)
- bisulfite pyrosequencing (1)
- black trout syndrome (1)
- bladder (1)
- blazars (1)
- blinatumoman (1)
- blinking (1)
- blocking phagocytosis (1)
- blood (1)
- blood-cerebrospinal fluid barrier (1)
- bone (1)
- bone adhesive (1)
- bone critical size defect (1)
- bone graft substitutes (1)
- bone marrow stromal cells (1)
- boolean modeling (1)
- boreholes (1)
- borohydrides (1)
- boronate (1)
- boronic acid (1)
- borylenes (1)
- bottom-up processing (1)
- brain (1)
- brain development (1)
- brain disorders (1)
- brain endothelial cell (1)
- brain endothelial cells (1)
- brain networks (1)
- brain plasticity (1)
- brain tumor (1)
- breast cancer (1)
- bridge-to-transplant (1)
- bronchoalveolar lavage fluid (1)
- bronchopulmonary dysplasia (1)
- brown trout (1)
- bullae (1)
- burn severity (1)
- burnt-wood (1)
- calcium (1)
- calcium phosphate (1)
- calnexin (1)
- calving front (1)
- cancer immunotherapy (1)
- cancer metabolism (1)
- carabid beetles (1)
- carbon (1)
- carbon monoxide (1)
- cardiac metabolism (1)
- cardiac remodelling (1)
- cardiac surgery (1)
- cardiolipin (1)
- cardiopulmonary bypass (1)
- cardiovascular genetics (1)
- cardiovascular risk factors (1)
- care (1)
- cartilage repair (1)
- catchment (1)
- catheterization (1)
- catheters (1)
- caveolin-1 (Cav-1) (1)
- cefotiam (1)
- cell biology (1)
- cell differentiation (1)
- cell migration (1)
- cell therapy (1)
- cell therapy and immunotherapy (1)
- ceramide (1)
- cerebral microbleeds (1)
- cerebrospinal fluid (1)
- cervical dystonia (1)
- channelrhodopsins (1)
- chemokine (1)
- chemokine receptor (1)
- child behavior (1)
- chimeric antigen receptor (1)
- chirality (1)
- chirality-induced spin selectivity (1)
- chlamydia (1)
- chlorophyll fluorescence imaging (1)
- cholesterol (1)
- cholesterol 25 hydroxylase (1)
- cholesteryl ester (1)
- chondrocyte (1)
- chondrogenesis (1)
- chronic kidney disease (CKD) (1)
- chronic non-bacterial osteomyelitis (1)
- circRNA (1)
- circadian rhythm (1)
- circular transcriptome sequencing (1)
- cisplatin (1)
- claudin-5 (1)
- climate extremes (1)
- clinical characteristics (1)
- clinical imaging (1)
- clinical outcome (1)
- clinical trial (1)
- cluster analysis (1)
- co-culture (1)
- coastline (1)
- cognitive control (1)
- coherence (1)
- coherent risk measures (1)
- cold adaptation (1)
- collagen sponge (1)
- collimator (1)
- collodion baby (1)
- collybistin (1)
- colonization (1)
- common diseases (1)
- comparative genomics (1)
- comparison (1)
- competition (1)
- complement deposition (1)
- complement factor H (1)
- complex DNA damage (1)
- composite material (1)
- composition (1)
- computer-mediated communication (1)
- concealed information test (1)
- conditioning (1)
- congruency sequences (1)
- consensus (1)
- conservation (1)
- constructed trade-offs (1)
- context-based teaching (1)
- contextual fear conditioning (1)
- continuous theta burst stimulation (cTBS) (1)
- continuum limit (1)
- control levels (1)
- convolutional neural network (1)
- copeptin (1)
- coping (1)
- copy number variation (1)
- cortical excitability (1)
- cortical silent period (1)
- count time series (1)
- cristal engeneering (1)
- crop statistics (1)
- cross-coupling (1)
- cross-sectional study (1)
- cryosphere (1)
- cryostructured scaffolds (1)
- curcumin (1)
- curvature (1)
- cuticular permeability (1)
- cyclic compounds (1)
- cyclophosphamide (FLAMSA) (1)
- cytoskeleton (1)
- cytotoxic (1)
- daratumumab (1)
- data warehouse (1)
- dead-wood enrichment (1)
- decay (1)
- deception (1)
- deep learning (1)
- default-interventionist framework (1)
- definition (1)
- dehydrocoupling (1)
- dehydrogenaticve borylation (1)
- democracy (1)
- democracy profiles (1)
- dendritic cell (1)
- depth dose curves (1)
- desk-based (1)
- desmin (1)
- desmin-related myopathy (1)
- desminopathy (1)
- desmoglein (1)
- desmoplastic small round cell tumor (1)
- desmosome (1)
- deubiquitinases (1)
- developmental forms (1)
- dexamethasone (1)
- diabetes (1)
- diacylglycerol (1)
- diacylglycerol (DAG) (1)
- diagnostic markers (1)
- dialysis adequacy (1)
- diazadiborinines (1)
- diboration (1)
- diborenes (1)
- diborynes (1)
- differentiation potential (1)
- diffuse large B-cell lymphoma (1)
- diffusion weighted mri (1)
- digital health (1)
- dimeric peptide (1)
- direct muss spectrometric profiling (1)
- discrete systems (1)
- dissolution rates (1)
- distractor-response binding (1)
- distributed control (1)
- distributed learning (1)
- distributions (1)
- diversity gradients (1)
- document analysis (1)
- domain-specific language (1)
- donor (1)
- donor-acceptor systems (1)
- dopamine (1)
- dorsal root ganglion (1)
- dosimetry (1)
- double arc (1)
- doxorubicin (1)
- driving simulation (1)
- drought (1)
- drug delivery (1)
- drug release (1)
- drug resistance evolution (1)
- dual setting system (1)
- duchenne muscular dystrophy (1)
- duplication-deficiency (1)
- dyes (1)
- dynamic facial emotion expression (1)
- dystonia (1)
- e(+)e(-) Collisions (1)
- early brain injury (1)
- early-life stress (1)
- earlywood (1)
- eccentric hypertrophy (1)
- ecosystem service (1)
- effective point of measurement (1)
- efficient intervention points (1)
- electrical resistivity tomography (1)
- electrochemistry (1)
- electron-precise diborates (1)
- elementary body (1)
- eletrhydrodynamic (1)
- emission (1)
- emotion enactment (1)
- emotion processing (1)
- emotion recognition (1)
- emotional behavior (1)
- emotions (1)
- emulsions oil-in-water (1)
- en bloc transfer (1)
- enantiomers (1)
- end-stage renal disease (1)
- endocytosis (1)
- endothelin-1 (1)
- endothelium (1)
- endurance (1)
- enercy-richness hypothesis (1)
- energy homeostasis (1)
- enhancer (1)
- environmental justice (1)
- enzyme mechanism (1)
- epidural block (1)
- epithelial-mesenchymal transition (1)
- error estimation (1)
- estimation error (1)
- ethics (1)
- eugenol (1)
- evapotranspiration (1)
- exciton (1)
- exciton-exciton (1)
- exercise intervention (1)
- expansion microscopy (1)
- expected value of control (1)
- extinction (1)
- extinction dynamics (1)
- extracellular domain (1)
- extramedullary hematopoiesis (1)
- extreme phenotypes (1)
- eye movement (1)
- eye movements (1)
- face (1)
- face-voice integration (1)
- faces (1)
- fan culture (1)
- fatigue (1)
- fault detection (1)
- fear (1)
- fear learning (1)
- febrile seizures (1)
- feminist rap (1)
- femoral head (1)
- fertility (1)
- fibre length (1)
- fibromyalgia (1)
- fibrotest (1)
- fission (1)
- flash freezing (1)
- flora (1)
- flourescence quantum yield (1)
- flu-like symptoms (1)
- fluerescence (1)
- fluorenscence (1)
- fluorescent probes (1)
- fluorine (1)
- fluoroarene (1)
- fluorogen-activating RNA aptamer (FLAP) (1)
- fluoroquinolone (1)
- food colorings (1)
- food resources (1)
- foraging patterns (1)
- forensic sample (1)
- forest ecology (1)
- forest fire (1)
- forest management (1)
- forest resources inventory (1)
- formation control (1)
- fractional variability (1)
- fracture (1)
- fragmentation functions (1)
- free choice (1)
- free radical polymerization (1)
- friut fly behaviour (1)
- full arc (1)
- fully convolutional neural networks (1)
- function (1)
- functional MRI (1)
- functional analysis (1)
- functional training (1)
- fungal molecular diagnostics (1)
- fungal rhodopsins (1)
- games (1)
- gangliosides and lipid rafts (1)
- gastric-bypass surgery (1)
- gastrointestinal cancer (1)
- gastrointestinal tract (1)
- gaze control (1)
- gem-bisboronates (1)
- gene alleles (1)
- gene expression analysis (1)
- gene family evolution (1)
- gene regulation (1)
- genetic engineering (1)
- genetic recombination (1)
- genome (1)
- genome analysis (1)
- genome-wide association studies (1)
- genomic imprinting (1)
- genotoxicity (1)
- glacier front (1)
- glacier terminus (1)
- glioblastoma multiforme (GBM) (1)
- glioma (1)
- global (1)
- global change (1)
- glucose transporter (1)
- glycine transporter 2 (1)
- glycoprotein Ibα (1)
- glycoprotein VI (1)
- glyvine uptake (1)
- graft vs. host disease (1)
- graft-versus host (1)
- graft-versus-host-disease (1)
- granules (1)
- gravitational waves (1)
- green fluorescence protein (GFP) (1)
- ground penetrating radar (1)
- ground-dwelling predators (1)
- growth (1)
- growth patterns (1)
- growth ring width (1)
- guided bone regeneration (1)
- guideline adherent treatment (1)
- guidelines (1)
- gut–liver axis (1)
- hA<sub>3</sub>AR (1)
- habit (1)
- habit strength (1)
- haematopoietic stem cell (1)
- halogens (1)
- head and neck squamous cell carcinoma (1)
- heart-to-mediastinum ratio (1)
- heat wave (1)
- helical molecules (1)
- helicenes (1)
- hematopoietic stem cell transplantation (1)
- heme oxygenase-1 (1)
- hemicraniectomy (1)
- hemodiafiltration (1)
- hemodialysis (1)
- hemophagocytosis (1)
- hemorrhagic (1)
- hemostasis (1)
- henoch-schönlein purpura (1)
- hepatitis B virus (1)
- hereditary breast and ovarian cancer (1)
- heterotypic scaffold design (1)
- high LET irradiation (1)
- high efficiency (1)
- high risk (1)
- high-resolution tandem mass spectrometry (1)
- hip fracture (1)
- hippocampus (1)
- histological subtype (1)
- histone H2AX (1)
- historical document analysis (1)
- historical printings (1)
- homogeneous catalysis (1)
- homogenization (1)
- honeybee (1)
- honeybees (1)
- hospital exemption (1)
- hospital-acquired methicillin-resistant Staphylococcus aureus (1)
- human adipose-derived stromal cells (1)
- human cerebral endothelial cells (1)
- human plasma (1)
- human xenografted mouse models (1)
- hybrid fabrication (1)
- hybrid materials (1)
- hydroboration (1)
- hydrological regime (1)
- hydroxyapatite (1)
- hydroxylation (1)
- hyperosmolality (1)
- hyperpersonal communication (1)
- hypertension (1)
- hypothermia (1)
- ichthyosis (1)
- identification (1)
- iliac crest (1)
- illness-death model (1)
- image processing (1)
- imaging (1)
- imaging PAM (1)
- immediate-early gene (1)
- immune evasion (1)
- immunity (1)
- immunotherapy of cancer (1)
- in vitro (1)
- in vitro model (1)
- in vitro models (1)
- incidence (1)
- indole-3-acetic acid (1)
- indolylpyrimidylpiperazines (1)
- infection biology (1)
- infections (1)
- infectious diseases (1)
- inflammatory gene (1)
- information extraction (1)
- inherited cardiomyopathies (1)
- inhibition (1)
- inhibitor (1)
- injection site reactions (1)
- injury (1)
- inmates (1)
- innate immune evasions (1)
- insect abundance (1)
- insect collection (1)
- insurance medicine (1)
- integrative management strategy (1)
- integrin α2 (1)
- intercomparison (1)
- interface (1)
- interferon beta (1)
- interleukin (1)
- interleukin-6 (1)
- intermediate dose Ara-C (1)
- intermediate filaments (1)
- intermittent exercise (1)
- internal carotid artery stenosis (1)
- intersession experiences (1)
- intersession processes (1)
- interval training (1)
- intestine (1)
- intracellular bacterial pathogens (1)
- intracranial bleeding (1)
- invasive aspergillosis (1)
- inventory (1)
- ionization chambers (1)
- ionization energy (1)
- ionization potential (1)
- iron metabolism (1)
- ischemia reperfusion injury (1)
- ischemia time (1)
- jet shapes (1)
- jet stream (1)
- jets (1)
- keratinocytes (1)
- key structure - fluorescence activation relationships (SFARs) (1)
- kidney (1)
- kinesin (1)
- kinesthesia (1)
- lag effect (1)
- land sharing (1)
- land surface (1)
- land use (1)
- language in media (1)
- late onset sepsis (1)
- late positive potential (1)
- lateral process of the talus (1)
- latewood (1)
- leaf width (1)
- library screening (1)
- lichen planus (1)
- lifestyle (1)
- ligand binding (1)
- ligand-receptor promiscuity (1)
- light-emitting-diodes (1)
- lignan (1)
- lineage-specific genes (1)
- linear conversion (1)
- linguistic cues (1)
- linguistic politics (1)
- lipid metabolism (1)
- liponeurocytoma (1)
- liquid biopsy (1)
- liver (1)
- liver metastases (1)
- local field potentials (1)
- logical trade-offs (1)
- long head of biceps tendon (1)
- long-term potentiation (1)
- loss of function (1)
- low-cost photometer (1)
- lowland beech forests (1)
- luminescence (1)
- lung metastases (1)
- lying (1)
- lymph nodes (1)
- lymphohistiocytosis (1)
- lyso-phospholipids (1)
- mAb engineering (1)
- mRNA (1)
- mTOR (1)
- macrophage polarization (1)
- macrophages (1)
- magnesium phosphate cement (1)
- maintenance therapy (1)
- major river basins (1)
- management (1)
- manga (1)
- match load (1)
- maternal separation (1)
- mating (1)
- mating preference (1)
- measurement (1)
- mebendazole (1)
- mechanical performance (1)
- mechanisms of disease (1)
- mechanistic modelling (1)
- medaka (1)
- medical rehabilitation (1)
- medication extraction (1)
- medicinal plant (1)
- medicine (1)
- medieval manuscripts (1)
- medulloblastoma (1)
- melatonin (1)
- melt electrowriting (MEW) (1)
- meningioma (1)
- meningococcal disease (1)
- meningococcus (1)
- mesenchymal stem cell (1)
- mesenchymal stem cells (1)
- mesenchymal stromal cell (1)
- mesentery (1)
- meta-analysis (1)
- metabolic flux (1)
- metabolic modeling (1)
- metabolic modelling (1)
- metabolic switch (1)
- metabolism (1)
- metabolism of infected and uninfected host cells (1)
- metabolomic (1)
- metabolomic profiling (1)
- metal complexenes (1)
- metallo-supramolecular polymer (1)
- metaproteomics (1)
- metastasis (1)
- metastasis-associated in colon cancer 1 (MACC1) (1)
- methods (1)
- methylation array (1)
- methylprednisolone (1)
- miR-221-5p (1)
- micelles (1)
- micro-chambers (1)
- microbial rhodopsins (1)
- microbial surface component recognising adhesive matrix molecules (1)
- microbiota (1)
- microfilament (1)
- microtubules (1)
- migrant (1)
- minerals (1)
- minimal residual disease (1)
- minipig (1)
- minocycline (1)
- mitochondrial genome (1)
- mitochondrial mRyR1 (1)
- mitofusin 2 (1)
- mitotic genes (1)
- mixed methods (1)
- mobile app (1)
- mobile health intervention (1)
- model-based diagnosis (1)
- molecular biology (1)
- molecular imaging (1)
- molecular signature (1)
- molecular structures (1)
- molecular subtypes (1)
- monitoring (1)
- monocyte-derived DC (1)
- monotoring (1)
- moonlighting (1)
- motility (1)
- motor-evoked potentials (MEP) (1)
- mouse feeding model (1)
- movement (1)
- mucormycosis (1)
- multi-spectral (1)
- multiresistance (1)
- mutants (1)
- mycophenolic acid (1)
- myelination (1)
- myeloid-derived suppressor cell (MDSC) (1)
- nano-satellite (1)
- nanocomplex (1)
- nanoparticles (1)
- nasal mucosal barrier function (1)
- native populations (1)
- natural language processing (1)
- natural pest control (1)
- naturalistic scenes (1)
- naïve B cells (1)
- necroptosis (1)
- neonatal outcome (1)
- neonates (1)
- nerve injury (1)
- nervous system (1)
- nest microbiota (1)
- neume notation (1)
- neurocytoma (1)
- neurodegenerative disease (1)
- neuroendocrine tumors (1)
- neuromuscular disease (1)
- neuronal (1)
- neuronal apoptosis (1)
- neurooncology (1)
- neuropathic pain (1)
- neurovascular unit (1)
- neutral sphingomyelinase-2 (1)
- neutrinos (1)
- next generation sequencing (1)
- next-generation sequencing (1)
- next-generation-sequencing (1)
- niche (1)
- nicknames (1)
- non-invasive fibrosis assessment (1)
- nonalcoholic fatty liver disease (1)
- noncoding RNA (1)
- noncovalent complex (1)
- noncovalent nanocomplex (1)
- normal distribution (1)
- nu SVR (1)
- nuclear envelope (1)
- nuclear export (1)
- number of (1)
- obesity (1)
- obstructive sleep apnoea (1)
- office environment (1)
- office-workers (1)
- oligodendrocyte (1)
- oncogenes (1)
- oncology (1)
- oncolysis (1)
- oncolytic vaccinia virus (1)
- online dating (1)
- online survey (1)
- ontology (1)
- optical character recognition (1)
- optical music recognition (1)
- optimal drug combination (1)
- optimal drug targeting (1)
- optimal pharmacological modulation (1)
- optimal treatment strategies (1)
- optimization (1)
- optogenetics (1)
- orthoreovirus (1)
- osteochondral defect (1)
- otakuism (1)
- outcome devaluation (1)
- ovarian cancer (1)
- overuse injury (1)
- oxidative DNA damage (1)
- oxidative stress (1)
- oxindole alkaloids (1)
- p-block element (1)
- p21-activated kinase Mbt/PAK4 (1)
- paediatrics (1)
- pain generator (1)
- panel sequencing (1)
- panic disorder (1)
- panniculitis (1)
- paranodopathy (1)
- parasexual recombination (1)
- parent-child relationship (1)
- parental perception (1)
- partial agonists (1)
- partial arc (1)
- passive transfer (1)
- patch-clamp (1)
- pathogenesis (1)
- pathogenic bacteria (1)
- peatland (1)
- pediatrics (1)
- peer review (1)
- pefloxacin (1)
- peginterferon bet-1a (1)
- pemphigus (1)
- penetration bias (1)
- penumbra (1)
- peptide inhibitor design (1)
- peptidomoics (1)
- performativity (1)
- pericytes (1)
- persistence (1)
- person identity processing (1)
- personality judgments (1)
- personalized medicine (1)
- perylene bisimide (1)
- perylene bisimides (1)
- pesicicles (1)
- pharmacophore map (1)
- phenolic compounds (1)
- phosphorescence (1)
- phosphorescene spectra (1)
- photoconductive interlayer (1)
- photodynamic chemotherapy (1)
- photoelectron spectroscopy (1)
- photolysis (1)
- photophysical prosperties (1)
- photophysics (1)
- physical activity (1)
- physical activity promotion (1)
- physical saliency (1)
- phytic acid (1)
- pi-conjugation (1)
- piRNA (1)
- piscine orthoreovirus (1)
- pit membrane diameter (1)
- placebo and nocebo effects (1)
- plan comparison (1)
- plant reproduction (1)
- plant-derived metabolites (1)
- plants (1)
- plant–microbe–pollinator triangle (1)
- plant–pathogen interaction (1)
- plaque cross-sectional area (1)
- plasma membrane (1)
- plasma membrane depolarization (1)
- plasminogen (1)
- platelet (1)
- platelet degranulation (1)
- platelets (1)
- point shear wave elastography (1)
- pointing task (1)
- pol(2-oxazoline) (1)
- polarimetery (1)
- pollination (1)
- pollination network (1)
- poly(2-oxazine) (1)
- poly(2-oxazoline) (1)
- polycaprolactone (1)
- polyglycerol sulfates (1)
- polynomials (1)
- polyphenols (1)
- population genetics (1)
- position estimation (1)
- positron (1)
- positron annihilation lifetime spectroscopy (1)
- post-fire management (1)
- post-translational modification (1)
- posttranscriptional control (1)
- powerlifting (1)
- precision medicine (1)
- predictive performance (1)
- premature aging (1)
- presynaptic hyperekplexia (1)
- preterm infants (1)
- primary endpoint (1)
- primary healthcare (1)
- primary outcome (1)
- primary vascular smooth muscle‐like cells (vSMCs) (1)
- probe-based real-time PCR (1)
- production machines (1)
- prognosis (1)
- prognostic marker (1)
- proliferation (1)
- proliferative darkening syndrome (1)
- prostate cancer (1)
- protected forests (1)
- protein binding (1)
- protein processing (1)
- protein transport (1)
- protein-bound uremic toxins (1)
- protein-protein interaction (PPI) (1)
- proteomics (1)
- psychological pain modulation (1)
- psychometrics (1)
- psychosocial adaptation (1)
- psychosocial stress (1)
- psychotherapy (1)
- puberty (1)
- pyrolysis (1)
- quality assurance (1)
- quality of democracy (1)
- quality of life (QoL) (1)
- quantile forecasts (1)
- quantitative analysis (1)
- questionnaires (1)
- radiation (1)
- radiation sensitivity (1)
- radical (1)
- radiopacity (1)
- radiotherapy (1)
- ray (1)
- reaction times (1)
- reactive intermediates (1)
- reactive oxygen species (1)
- real life setting (1)
- real world evidence (1)
- reciprocal translocation (1)
- recombinant tissue-type plasminogen activator (1)
- reconstructive surgery (1)
- rectum (1)
- refractory aGvHD (1)
- regulatory T cells (Treg) (1)
- regulatory capital (1)
- regulatory dendritic cells (1)
- reliability (1)
- renal imaging (1)
- repeated sprint (1)
- reprogamming of host cell metabolism (1)
- required hydrophilic–lipophilic balance (1)
- rereading (1)
- resettlement refugees (1)
- resistance (1)
- resonance theory (1)
- restrictive cardiomyopathy (1)
- resveratrol biosynthesis (1)
- retention interval (1)
- reticulate body (1)
- retinal pigment epithelium (1)
- retrospective (1)
- review (1)
- rhBMP–2 (1)
- rheumatoid arthritis (1)
- ring-expansion reactions (1)
- ripk1 (1)
- ripk3 (1)
- risk stratification (1)
- robust control (1)
- ruthenium (1)
- saccades (1)
- sacha inchi oil (1)
- sample storage (1)
- saproxylic organisms (1)
- sarcomere (1)
- satellite formation flying (1)
- satellite remote sensing (1)
- scaffold (1)
- screening (1)
- search (1)
- secondary prevention (1)
- secreted effectors (1)
- segmental progeria (1)
- semantic segmentation (1)
- semileptonic & radiative decays (1)
- sensor data (1)
- sensor supports (1)
- sentinel (1)
- sentinel prey (1)
- sepsis (1)
- sequence analysis (1)
- sequential addition (1)
- serotonin (1)
- serotonin deficiency (1)
- setting reaction (1)
- sex robots (1)
- short-range order (1)
- shoulder (1)
- shoulder pain (1)
- shyness (1)
- sigma boranes (1)
- signal specification (1)
- signalling (1)
- silica supraparticles (1)
- simulation and modeling (1)
- simultaneous presentation paradigm (1)
- single arc (1)
- single photon (1)
- single-molecule tracking (1)
- sirolimus (1)
- skeletal progenitor cells (1)
- skewness (1)
- slope bogs (1)
- small intestinal submucosa scaffold (1)
- small-cell lung cancer (1)
- smart surfaces (1)
- snowboarder's ankle (1)
- snowboarder's fracture (1)
- soccer (football) (1)
- social anxiety disorder (1)
- social attention (1)
- sociophonetics (1)
- sodium (1)
- soft tissue sarcoma (1)
- software (1)
- soil fauna (1)
- solar cells (1)
- solid tumors (1)
- solid-state NMR spectroscopy (1)
- solid-state emitters (1)
- solitary bees (1)
- solubility enhancement (1)
- solvent-dependent fluorescence yield (1)
- somatic mutations (1)
- somatosensory evoked potential (1)
- somatosensory temporal discrimination (1)
- spa typing (1)
- spacing effect (1)
- spatial analyses (1)
- spatial heterogeneity (1)
- spatial scale (1)
- species richness (1)
- species‐area hypothesis (1)
- sphingomyelinase (1)
- sphingosine kinase (1)
- sphingosine kinase inhibitor SKI-II (1)
- sphingosine-1-phosphate (1)
- spin polarization (1)
- spin transport (1)
- spinal muscular atrophy (1)
- spleen (1)
- split renal function (1)
- sporidia (1)
- standing (1)
- starPEG hydrogel (1)
- startle response (1)
- static vs. dynamic faces (1)
- statistical distributions (1)
- statistical models (1)
- steering (1)
- stem Cells (1)
- stem cell transplantation (1)
- stereospecific sythesis (1)
- stereotactic body radiation therapy (1)
- stereotactic irradiation (1)
- steric effects (1)
- steroid-resistant aGvHD (1)
- storage-pool diseases (1)
- strength training (1)
- stress (1)
- stress fiber (1)
- stress tolerance (1)
- stromal vascular fraction (1)
- structural disruption (1)
- structure-activity (1)
- structure-activity relationships (1)
- structured illumination microscopy (1)
- subadditivity (1)
- subarachnoid hemorrhage (1)
- submicroscopic chromosome rearrangement (1)
- subsarcolemmal mitochondria (1)
- substituent (1)
- subsurface hydrology (1)
- subthalamic nucleus (1)
- sulfoimines (1)
- sulfur (1)
- super resolution microscopy (1)
- super-resolution microscopy (1)
- superresolution (1)
- suppressor mutation (1)
- surface transport (1)
- surface water (1)
- surgical and invasive medical procedures (1)
- surgical site infection (1)
- survival analysis (1)
- synchrotron radiation (1)
- synchrotron radiatoren (1)
- synergistic effect (1)
- synthesis (1)
- systematic affiliation (1)
- targeted bisulfite sequencing (1)
- targeted therapies (1)
- targeted therapy (1)
- taxonomy (1)
- temozolomide (1)
- temperature‐mediated resource exploitation hypothesis (1)
- temperature‐richness hypothesis (1)
- temporal discrimination threshold (1)
- temporal lobe epilepsy (1)
- tendon-derived stem cell (1)
- terrestrial LiDAR (1)
- theranostics (1)
- therapy (1)
- therapy response (1)
- thermal remote sensing (1)
- thrombo-inflammation (1)
- thrombosis (1)
- tight junctions (1)
- time lag (1)
- time series (1)
- tisindoline (1)
- top-down processing (1)
- topminnow (1)
- total body irradiation/busulfan (1)
- toxicity (1)
- transcranial magnetic simulation (TMS) (1)
- transcription (1)
- transcription deficiency (1)
- transient dynamics (1)
- transient elastography (1)
- transient ischemic attack (1)
- transient middle cerebral artery occlusion (1)
- transition metal (1)
- transmission (1)
- transplantation (1)
- transposable elements (1)
- tree cavities (1)
- triacylglycerides (1)
- triarylboranes (1)
- triple bonds (1)
- trivalent boron (1)
- trypanosomes (1)
- tryptophan hydroxylase 2 (1)
- tumor burden (1)
- tumor control probability (1)
- tumor heterogeneity (1)
- tumor suppressor miRNA (1)
- tumour-necrosis factors (1)
- two-photon absorption (1)
- tyloses (1)
- type VII secretion system (1)
- ubiquitin ligase (1)
- ubiquitylation (ubiquitination) (1)
- uncanny valley (1)
- uncertainties (1)
- uncertainty (1)
- uneven-aged mountainous (1)
- unmanaged broadleaved forests (1)
- unsaturated fatty acids (1)
- upconversion (1)
- uptake (1)
- urban environments (1)
- uremic toxins (1)
- urinary tract infections (1)
- vaccinia (1)
- variability (1)
- vasculitis (1)
- vertebral body (1)
- vertical and radial variation (1)
- very high energies (VHE) (1)
- very long-chain aliphatic compounds (1)
- vessel lumen diameter (1)
- vestibular schwannoma (1)
- video laryngoscopy (1)
- virotherapy (1)
- virtual isocenter (1)
- viruses (1)
- visual orientation (1)
- visual perception (1)
- visual realism (1)
- vitamin D (1)
- vitamins (1)
- voice-face matching (1)
- volume overload (1)
- walking (1)
- water balance (1)
- watershed (1)
- weightlifting (1)
- well-being (1)
- white matter lesions (1)
- whole-genome duplication (1)
- whole-genome sequencing (1)
- wild bees (1)
- wood anatomy (1)
- work (1)
- work capacity evaluation (1)
- work engagement (1)
- work performance (1)
- wound healing (1)
- youth (1)
- zinc oxide (1)
- zinc oxide nanoparticles (1)
- zonal construct (1)
Institute
- Theodor-Boveri-Institut für Biowissenschaften (72)
- Physikalisches Institut (24)
- Medizinische Klinik und Poliklinik II (23)
- Neurologische Klinik und Poliklinik (22)
- Institut für Anorganische Chemie (19)
- Institut für Psychologie (19)
- Institut für Geographie und Geologie (18)
- Medizinische Klinik und Poliklinik I (17)
- Institut für Hygiene und Mikrobiologie (16)
- Institut für Organische Chemie (16)
Sonstige beteiligte Institutionen
- Department of Hematology and Oncology, Sana Hospital Hof, Hof, Germany (1)
- Department of Laboratory Medicine and Medicine Huddinge, Karolinska Institutet and University Hospital, Stockholm, Sweden (1)
- Department of Medicine A, University Hospital of Münster, Münster, Germany (1)
- IZKF Nachwuchsgruppe Geweberegeneration für muskuloskelettale Erkrankungen (1)
- Interdisciplinary Center for Clinical Research (1)
- Johns Hopkins School of Medicine (1)
- University of Bari Medical School, Bari, Italy (1)
Fanconi anemia (FA) is a genetically heterogeneous disorder with 22 disease-causing genes reported to date. In some FA genes, monoallelic mutations have been found to be associated with breast cancer risk, while the risk associations of others remain unknown. The gene for FA type C, FANCC, has been proposed as a breast cancer susceptibility gene based on epidemiological and sequencing studies. We used the Oncoarray project to genotype two truncating FANCC variants (p.R185X and p.R548X) in 64,760 breast cancer cases and 49,793 controls of European descent. FANCC mutations were observed in 25 cases (14 with p.R185X, 11 with p.R548X) and 26 controls (18 with p.R185X, 8 with p.R548X). There was no evidence of an association with the risk of breast cancer, neither overall (odds ratio 0.77, 95%CI 0.44–1.33, p = 0.4) nor by histology, hormone receptor status, age or family history. We conclude that the breast cancer risk association of these two FANCC variants, if any, is much smaller than for BRCA1, BRCA2 or PALB2 mutations. If this applies to all truncating variants in FANCC it would suggest there are differences between FA genes in their roles on breast cancer risk and demonstrates the merit of large consortia for clarifying risk associations of rare variants.
Polymer micelles are an attractive means to solubilize water insoluble compounds such as drugs. Drug loading, formulations stability and control over drug release are crucial factors for drug‐loaded polymer micelles. The interactions between the polymeric host and the guest molecules are considered critical to control these factors but typically barely understood. Here, we compare two isomeric polymer micelles, one of which enables ultra‐high curcumin loading exceeding 50 wt.%, while the other allows a drug loading of only 25 wt.%. In the low capacity micelles, steady‐state fluorescence revealed a very unusual feature of curcumin fluorescence, a high energy emission at 510 nm. Time‐resolved fluorescence upconversion showed that the fluorescence life time of the corresponding species is too short in the high‐capacity micelles, preventing an observable emission in steady‐state. Therefore, contrary to common perception, stronger interactions between host and guest can be detrimental to the drug loading in polymer micelles.
Background
The vast majority of cases with Beckwith-Wiedemann syndrome (BWS) are caused by a molecular defect in the imprinted chromosome region 11p15.5. The underlying mechanisms include epimutations, uniparental disomy, copy number variations, and structural rearrangements. In addition, maternal loss-of-function mutations in CDKN1C are found. Despite growing knowledge on BWS pathogenesis, up to 20% of patients with BWS phenotype remain without molecular diagnosis.
Case presentation
Herein, we report an Iranian family with two females affected with BWS in different generations. Bisulfite pyrosequencing revealed hypermethylation of the H19/IGF2: intergenic differentially methylated region (IG DMR), also known as imprinting center 1 (IC1) and hypomethylation of the KCNQ1OT1: transcriptional start site (TSS) DMR (IC2). Array CGH demonstrated an 8 Mb duplication on chromosome 11p15.5p15.4 (205,827-8,150,933) and a 1 Mb deletion on chromosome 9p24.3 (209,020-1,288,114). Chromosome painting revealed that this duplication-deficiency in both patients is due to unbalanced segregation of a paternal reciprocal t(9;11)(p24.3;p15.4) translocation.
Conclusions
This is the first report of a paternally inherited unbalanced translocation between the chromosome 9 and 11 short arms underlying familial BWS. Copy number variations involving the 11p15.5 region are detected by the consensus diagnostic algorithm. However, in complex cases which do not only affect the BWS region itself, characterization of submicroscopic chromosome rearrangements can assist to estimate the recurrence risk and possible phenotypic outcomes.
For the understanding of the variable, transient and non-thermal universe, unbiased long-term monitoring is crucial. To constrain the emission mechanisms at the highest energies, it is important to characterize the very high energy emission and its correlation with observations at other wavelengths. At very high energies, only a limited number of instruments is available. This article reviews the current status of monitoring of the extra-galactic sky at TeV energies.
Understanding extinction debts: spatio-temporal scales, mechanisms and a roadmap for future research
(2019)
Extinction debt refers to delayed species extinctions expected as a consequence of ecosystem perturbation. Quantifying such extinctions and investigating long‐term consequences of perturbations has proven challenging, because perturbations are not isolated and occur across various spatial and temporal scales, from local habitat losses to global warming. Additionally, the relative importance of eco‐evolutionary processes varies across scales, because levels of ecological organization, i.e. individuals, (meta)populations and (meta)communities, respond hierarchically to perturbations. To summarize our current knowledge of the scales and mechanisms influencing extinction debts, we reviewed recent empirical, theoretical and methodological studies addressing either the spatio–temporal scales of extinction debts or the eco‐evolutionary mechanisms delaying extinctions. Extinction debts were detected across a range of ecosystems and taxonomic groups, with estimates ranging from 9 to 90% of current species richness. The duration over which debts have been sustained varies from 5 to 570 yr, and projections of the total period required to settle a debt can extend to 1000 yr. Reported causes of delayed extinctions are 1) life‐history traits that prolong individual survival, and 2) population and metapopulation dynamics that maintain populations under deteriorated conditions. Other potential factors that may extend survival time such as microevolutionary dynamics, or delayed extinctions of interaction partners, have rarely been analyzed. Therefore, we propose a roadmap for future research with three key avenues: 1) the microevolutionary dynamics of extinction processes, 2) the disjunctive loss of interacting species and 3) the impact of multiple regimes of perturbation on the payment of debts. For their ability to integrate processes occurring at different levels of ecological organization, we highlight mechanistic simulation models as tools to address these knowledge gaps and to deepen our understanding of extinction dynamics.
Alien limb phenomenon is a rare syndrome associated with a feeling of non-belonging and disowning toward one's limb. In contrast, anarchic limb phenomenon leads to involuntary but goal-directed movements. Alien/anarchic limb phenomena are frequent in corticobasal syndrome (CBS), an atypical parkinsonian syndrome characterized by rigidity, akinesia, dystonia, cortical sensory deficit, and apraxia. The structure function relationship of alien/anarchic limb was investigated in multi centric structural magnetic resonance imaging (MRI) data. Whole-group and single subject comparisons were made in 25 CBS and eight CBS-alien/anarchic limb patients versus controls. Support vector machine was used to see if CBS with and without alien/anarchic limb could be distinguished by structural MRI patterns. Whole-group comparison of CBS versus controls revealed asymmetric frontotemporal atrophy. CBS with alien/anarchic limb syndrome versus controls showed frontoparietal atrophy including the supplementary motor area contralateral to the side of the affected limb. Exploratory analysis identified frontotemporal regions encompassing the pre-/and postcentral gyrus as compromised in CBS with alien limb syndrome. Classification of CBS patients yielded accuracies of 79%. CBS-alien/anarchic limb syndrome was differentiated from CBS patients with an accuracy of 81%. Predictive differences were found in the cingulate gyrus spreading to frontomedian cortex, postcentral gyrus, and temporoparietoocipital regions. We present the first MRI-based group analysis on CBS-alien/anarchic limb. Results pave the way for individual clinical syndrome prediction and allow understanding the underlying neurocognitive architecture. (C) 2019 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Fungi of the order Mucorales colonize all kinds of wet, organic materials and represent a permanent part of the human environment. They are economically important as fermenting agents of soybean products and producers of enzymes, but also as plant parasites and spoilage organisms. Several taxa cause life-threatening infections, predominantly in patients with impaired immunity. The order Mucorales has now been assigned to the phylum Mucoromycota and is comprised of 261 species in 55 genera. Of these accepted species, 38 have been reported to cause infections in humans, as a clinical entity known as mucormycosis. Due to molecular phylogenetic studies, the taxonomy of the order has changed widely during the last years. Characteristics such as homothallism, the shape of the suspensors, or the formation of sporangiola are shown to be not taxonomically relevant. Several genera including Absidia, Backusella, Circinella, Mucor, and Rhizomucor have been amended and their revisions are summarized in this review. Medically important species that have been affected by recent changes include Lichtheimia corymbifera, Mucor circinelloides, and Rhizopus microsporus. The species concept of Rhizopus arrhizus (syn. R. oryzae) is still a matter of debate. Currently, species identification of the Mucorales is best performed by sequencing of the internal transcribed spacer (ITS) region. Ecologically, the Mucorales represent a diverse group but for the majority of taxa, the ecological role and the geographic distribution remain unknown. Understanding the biology of these opportunistic fungal pathogens is a prerequisite for the prevention of infections, and, consequently, studies on the ecology of the Mucorales are urgently needed.
Ureaplasma species are common colonizers of the adult genitourinary tract and often considered as low-virulence commensals. Intraamniotic Ureaplasma infections, however, facilitate chorioamnionitis and preterm birth, and cases of Ureaplasma-induced neonatal sepsis, pneumonia, and meningitis raise a growing awareness of their clinical relevance. In vitro studies are scarce but demonstrate distinct Ureaplasma-driven impacts on immune mechanisms. The current study addressed cytokine and chemokine responses upon exposure of native or lipopolysaccharide (LPS) co-stimulated human brain microvascular endothelial cells (HBMEC) to Ureaplasma urealyticum or U. parvum, using qRT-PCR, RNA sequencing, multi-analyte immunoassay, and flow cytometry. Ureaplasma exposure in native HBMEC reduced monocyte chemoattractant protein (MCP)-3 mRNA expression (p < 0.01, vs. broth). In co-stimulated HBMEC, Ureaplasma spp. attenuated LPS-evoked mRNA responses for C-X-C chemokine ligand 5, MCP-1, and MCP-3 (p < 0.05, vs. LPS) and mitigated LPS-driven interleukin (IL)-1α protein secretion, as well as IL-8 mRNA and protein responses (p < 0.05). Furthermore, Ureaplasma isolates increased C-X-C chemokine receptor 4 mRNA levels in native and LPS co-stimulated HBMEC (p < 0.05). The presented results may imply immunomodulatory capacities of Ureaplasma spp. which may ultimately promote chronic colonization and long-term neuroinflammation.
As structural membrane components and signaling effector molecules sphingolipids influence a plethora of host cell functions, and by doing so also the replication of viruses. Investigating the effects of various inhibitors of sphingolipid metabolism in primary human peripheral blood lymphocytes (PBL) and the human B cell line BJAB we found that not only the sphingosine kinase (SphK) inhibitor SKI-II, but also the acid ceramidase inhibitor ceranib-2 efficiently inhibited measles virus (MV) replication. Virus uptake into the target cells was not grossly altered by the two inhibitors, while titers of newly synthesized MV were reduced by approximately 1 log (90%) in PBL and 70–80% in BJAB cells. Lipidomic analyses revealed that in PBL SKI-II led to increased ceramide levels, whereas in BJAB cells ceranib-2 increased ceramides. SKI-II treatment decreased sphingosine-1-phosphate (S1P) levels in PBL and BJAB cells. Furthermore, we found that MV infection of lymphocytes induced a transient (0.5–6 h) increase in S1P, which was prevented by SKI-II. Investigating the effect of the inhibitors on the metabolic (mTORC1) activity we found that ceranib-2 reduced the phosphorylation of p70 S6K in PBL, and that both inhibitors, ceranib-2 and SKI-II, reduced the phosphorylation of p70 S6K in BJAB cells. As mTORC1 activity is required for efficient MV replication, this effect of the inhibitors is one possible antiviral mechanism. In addition, reduced intracellular S1P levels affect a number of signaling pathways and functions including Hsp90 activity, which was reported to be required for MV replication. Accordingly, we found that pharmacological inhibition of Hsp90 with the inhibitor 17-AAG strongly impaired MV replication in primary PBL. Thus, our data suggest that treatment of lymphocytes with both, acid ceramidase and SphK inhibitors, impair MV replication by affecting a number of cellular activities including mTORC1 and Hsp90, which alter the metabolic state of the cells causing a hostile environment for the virus.
Virotherapy on the basis of oncolytic vaccinia virus (VACV) strains is a promising approach for cancer therapy. Recently, we showed that the oncolytic vaccinia virus GLV-1h68 has a therapeutic potential in treating human prostate and hepatocellular carcinomas in xenografted mice. In this study, we describe the use of dynamic boolean modeling for tumor growth prediction of vaccinia virus-injected human tumors. Antigen profiling data of vaccinia virus GLV-1h68-injected human xenografted mice were obtained, analyzed and used to calculate differences in the tumor growth signaling network by tumor type and gender. Our model combines networks for apoptosis, MAPK, p53, WNT, Hedgehog, the T-killer cell mediated cell death, Interferon and Interleukin signaling networks. The in silico findings conform very well with in vivo findings of tumor growth. Similar to a previously published analysis of vaccinia virus-injected canine tumors, we were able to confirm the suitability of our boolean modeling for prediction of human tumor growth after virus infection in the current study as well. In summary, these findings indicate that our boolean models could be a useful tool for testing of the efficacy of VACV-mediated cancer therapy already before its use in human patients.