Refine
Has Fulltext
- yes (133)
Year of publication
Document Type
- Book article / Book chapter (133) (remove)
Language
- English (133) (remove)
Keywords
- Animal Studies (23)
- Cultural Animal Studies (23)
- Cultural Studies (23)
- Ecocriticism (23)
- Environmental Humanities (23)
- Human-Animal Studies (23)
- Literary Studies (23)
- cultural studies (13)
- Kulturwissenschaften (12)
- Psychologie (11)
- Adenosinrezeptor (5)
- India (5)
- Indien (5)
- Globalisierung (4)
- Hall, Stuart (4)
- Williams, Raymond (4)
- Feminismus (3)
- Internationalität (3)
- feminism (3)
- globalization (3)
- Adenosin (2)
- Alltagskultur (2)
- Aristeas (2)
- Aristeas-Brief (2)
- DNS (2)
- Entstehung (2)
- Fingerprint-Verfahren (2)
- Letter of Aristeas (2)
- Längsschnittuntersuchung (2)
- Marxismus (2)
- Marxist theory (2)
- Medizin (2)
- Nationale Minderheiten (2)
- Pädagogik (2)
- Rassismus (2)
- Social interaction (2)
- Spivak, Gayatri Chakravorty (2)
- Tumor (2)
- Wissen (2)
- education (2)
- internationalism (2)
- language (2)
- minorities (2)
- ordinary culture (2)
- politics of representation (2)
- racism (2)
- transnationalism (2)
- 2-acetylaminofluorene (1)
- Ad Philocratem (1)
- Alphabetisierung (1)
- Aminosäuren (1)
- Aquinas (1)
- Aristeas 〈Epistolographus, ca. v3. Jh.〉 (1)
- Aristeas, Epistolographus : Ad Philocratem (1)
- Ausgrabung (1)
- Barbiturat (1)
- Behinderung (1)
- Beifahrer (1)
- Bibel. Judit, 10-13 (1)
- Bildung (1)
- Burley (1)
- CNTF (1)
- Carcinogen (1)
- Carcinogenität (1)
- Contributors (1)
- Cyropaidia (1)
- DNA (1)
- DNS-Bindung (1)
- Differential psychopharmacology (1)
- Digitalisierung (1)
- Einfluss (1)
- Elektrofusion (1)
- Elektroporation (1)
- English (1)
- English youth slang (1)
- English-language digital discourse (1)
- Entwicklung (1)
- Ernährung (1)
- Eukaryonten / Chromosom (1)
- Expedition (1)
- Extremwertstatistik (1)
- FGF-5 (1)
- Film (1)
- Gedächtnis (1)
- Gedächtnisbildung (1)
- Gefühl (1)
- Genetik (1)
- Geschlecht (1)
- Gesetz der kleinen Zahlen (1)
- Gewalt / Frau (1)
- Gilroy, Paul: The Black Atlantic (1)
- God in 3 Macc (1)
- Gott (1)
- Hellenistic kingship (1)
- Hochbegabung (1)
- Holofernes (1)
- Humangenetik (1)
- IGF-I (1)
- Identitätsentwicklung (1)
- Informationsverarbeitung / Kognition (1)
- Interkulturalität (1)
- Irak (1)
- Isocrates (1)
- Jameson, Frederic (1)
- Japan (1)
- Judit <Buch> (1)
- Judith <Book> (1)
- Judith und Holofernes (1)
- Kaste (1)
- Kognitive Entwicklung / Informationsverarbeitung / Kind / Informationsintegration (1)
- Kraftfahrer (1)
- Kriminalpsychologie / Aufsatzsammlung (1)
- Kulturpolitik (1)
- Kulturtheorie (1)
- Kulturwissenschaft (1)
- Lebendgebärende Zahnkarpfen (1)
- Lebensalter (1)
- Lernerfolg (1)
- Lernpsychologie (1)
- Lerntheorie (1)
- Lokales Wissen (1)
- Maccabees (1)
- Mastzelle (1)
- Medien (1)
- Mehta, Deepa (1)
- Metagedächtnis (1)
- Methode (1)
- Molekularbiologie (1)
- Mord (1)
- Motorische Entwicklung (1)
- NGF gene family (1)
- Nahrung (1)
- Nationale Traditionen (1)
- Niere (1)
- Nigeria (1)
- Ockham (1)
- Oogenese (1)
- Orientalistik (1)
- Persönlichkeitsentwicklung (1)
- Pharmakologie (1)
- Poisson-Prozess (1)
- Politische Ethik (1)
- Postmarxismus (1)
- Praxis (1)
- Psychometrie (1)
- Pädagogische Psychologie (1)
- RNA (1)
- RNA cleavage (1)
- Ratte (1)
- Regressionsanalyse (1)
- Religion (1)
- Representation (1)
- Risikoanalyse (1)
- Saccharomyces cerevisiae (1)
- Schreiben (1)
- Schrift (1)
- Schulleistung (1)
- Schwertkärpfling (1)
- Selbstmordgefährdung (1)
- Septuagint (1)
- Septuaginta (1)
- Social role (1)
- Soziale Rolle (1)
- Sozialphilosophie (1)
- Sprache (1)
- Sprachgebrauch (1)
- Strategie (1)
- Styrol (1)
- Subjektivität (1)
- Suizidalität (1)
- Tell Jikan (1)
- Tell Khirbet Salih (1)
- Textverarbeitung <Psycholinguistik> (1)
- Theorie (1)
- Toxikologie (1)
- Transnationalismus (1)
- Trunkenheit im Verkehr (1)
- Tumor / Zellteilung (1)
- Unterricht (1)
- Unterrichtspsychologie (1)
- Vereinigte Staaten (1)
- Wallace, Michele (1)
- Widerstand (1)
- Wiliams, Raymond (1)
- Willams, Raymond (1)
- Xenophon (1)
- Zambian English (1)
- Zelle (1)
- Zellkern (1)
- Zellteilung (1)
- adduct (1)
- aflatoxin B1 (1)
- aggression (1)
- aphorism (1)
- background (1)
- basic learners (1)
- behavioural analysis (1)
- bilingualism (1)
- binding (1)
- blended learning (1)
- carcinogen (1)
- caste system (1)
- catalytic DNA (1)
- common human values and national values (1)
- communication (1)
- component (1)
- connection (1)
- contextual clues (1)
- covalent (1)
- cultural politics (1)
- cultural theory (1)
- culture (1)
- curriculum (1)
- cyber aggression (1)
- density gradient centrifugation (1)
- deoxyribozymes (1)
- depression (1)
- development (1)
- differential centrifugation (1)
- differential psychology (1)
- digit (1)
- digitalization (1)
- disability (1)
- discourses of gender and ethnicity (1)
- dose (1)
- drug-personality interaction (1)
- dyadic interaction (1)
- e-Government (1)
- epitranscriptomics (1)
- equivocation (1)
- expression (1)
- extrapolation (1)
- film analysis (1)
- food cultures (1)
- foreign (1)
- gender (1)
- gene targeting (1)
- grammar (1)
- heterogeneous population (1)
- imposition (1)
- in vitro selection (1)
- individual (1)
- interaction (1)
- intercultural pedagogy (1)
- justice (1)
- lIF (1)
- label-free quantification (1)
- language variation (1)
- learner (1)
- learning process (1)
- linguistics (1)
- local culture of knowledge (1)
- looking behaviour (1)
- majority (1)
- mass spectrometry (1)
- mathematical linguistics (1)
- metaphor (1)
- methodology of differential psychopharmacology (1)
- modified RNA nucleotides (1)
- moral elitism (1)
- national traditions (1)
- neologism (1)
- neurotrophic molecules (1)
- new normal (1)
- organellar mapping (1)
- perceptions (1)
- peroxisome purification (1)
- political discourse (1)
- post Marxism (1)
- presidential rhetoric (1)
- programming languages (1)
- proskynesis (1)
- protein localization (1)
- reactions (1)
- religion (1)
- risk (1)
- rules of syntax (1)
- second language acquisition (1)
- semiotics (1)
- signification (1)
- single case study (1)
- social (1)
- social philosophy (1)
- spatial proteomics (1)
- speech (1)
- speech community (1)
- subjectivity (1)
- subversiveness (1)
- suicidality (1)
- suppression of women (1)
- susceptibility (1)
- teaching process (1)
- text processing (1)
- transference (1)
- tumour (1)
- undergraduates of EFL and teachers (1)
- verbal and nonverbal behaviour (1)
- verbal and nonverbal communication (1)
- vocabulary (1)
- vocabulary knowledge (1)
- vocabulary retention (1)
- worship (1)
- xenophobia (1)
Institute
- Neuphilologisches Institut - Moderne Fremdsprachen (48)
- Institut für Psychologie (bis Sept. 2007) (23)
- Institut für deutsche Philologie (23)
- Institut für Pharmakologie und Toxikologie (14)
- Theodor-Boveri-Institut für Biowissenschaften (14)
- Institut für Psychologie (8)
- Institut für Biblische Theologie (7)
- Institut für Internationales Recht, Europarecht und Europäisches Privatrecht (3)
- Neuphilologisches Institut - Moderne Fremdsprachen (bis 2007) (3)
- Institut für Mineralogie und Kristallstrukturlehre (2)
- Institut für Molekulare Infektionsbiologie (2)
- Institut für Altertumswissenschaften (1)
- Institut für Altertumswissenschaften (bis Sept. 2007) (1)
- Institut für Klinische Neurobiologie (1)
- Institut für Mathematik (1)
- Institut für Organische Chemie (1)
- Institut für Philosophie (1)
- Institut für Politische Wissenschaft (1)
- Lehrstuhl für Biochemie (1)
Schriftenreihe
- Cultural Animal Studies, Band 3 (23)
- Deuterocanonical and Cognate Literature Studies (1)
- Deuterocanonical and Cognate Literature Yearbook (1)
- International Archives of the History of Ideas / Archives internationales d’histoire des idées 242 (1)
- Methods in Molecular Biology 2533 (1)
- Methods in Molecular Biology; 2643 (1)
Sonstige beteiligte Institutionen
The ligand-binding subunit ofthe A1 adenosine receptor has been identified in membranes with the photoaffinity Iabel R-2-azido-N6-p-hydroxyphenylisopropyladenosine (R-AHPIA). Covalent labelling ofthe A1 receptor can also be achieved in intact cells. The dissociation of the radioiodinated label (1251-AHPIA) from isolated rat fat cells was incomplete after UV irradiation, leaving about 20°/o of irreversible specific binding. Such covalent labelling of the receptor led to a concentration-dependent reduction of cellular cyclic AMP levels. This persistent effect of covalent labeHing occurred with an IC50 value of 9 nM, as compared to an IC50 value of 0.9 nM for the direct reduction of cyclic AMP Ievels by the ligand. The difference in the IC5o values can be explained by assuming spare receptors. This hypothesis was verified in binding studies using [ 3HJPIA as a radioligand. R-AHPIA inhibited binding of [3H)PIA to intact fat cells with a K1 value of about 20 nM, which is about 20 tim es high er than the corresponding IC50 value of cyclic AMP reduction. These data show that the A1 receptor is activated according to the occupancy theory. The high sensitivity of the activation in intact ceJis is due to a large number of spare receptors.
Comprehensive geochemical investigations of rnetabasites yielded constraints for a correlation of, or discrimination between the different tectonic units within the northeast Bavarian crystalline basement. The Münchberg nappe pile consists of at least five large tectonic units which exhibit differences in lithology, in part also in metamorphie grade and in metamorphie history. The metabasites in each of these nappes show their own, significant geochemical characteristics. The lowermost tectonic unit, the Bavarian lithofacies, includes the anchimetamorphie Ordovician Randschieferserie which contains alkaline basalts. In their geochemistry, they are sirnilar to the metabasites of the Fichtelgebirge crystalline complex in the autochthonous Saxo-thuringian. The next higher tectonic unit of the Münchberg nappe pile, the Prasinit-Phyllit-Serie contains metabasites which can be derived from subalkaline basalts with a clear calc-alkaline tendency. There is a striking geochemical resemblance to the metabasites of the Erbendorf Greenschist Zone (EGZ) underscorinq the similar lithology of both allochthonous units which appear to be in a similar tectonic position. The Randamphibolit-Serie higher up in the Münchberg nappe pile consists of metabasites with tholeiitic characteristics and a pronounced differentiation trend. The next higher tectonic unit, the Liegendserie of the Münchberg gneiss cornplex s. str., contains metagabbros to metagabbronorites with a high-Al basaltic composition. The amphibolites and banded hornblende gneisses of the overlying Hangendserie are of subalkaline basaltic character with calc-alkaline affinity. The Zone Erbendorf-Vohenstrauss (ZEV) is currently regarded as an allochthonous unit equivalent to the higher crystalline nappes of the Münchberg pile. However, the geochemical character of the metabasites do not encourage such a correlation. Neither the schistose and striped amphibolites nor the flaseramphibolites of the ZEV with their N-KORB and E-MORB character respectively, find convincing counterparts in the crystalline nappes of the Münchberg pile. However, an interestingly close resemblance exists between the schistose and striped amphibolites in the ZEV, on the one hand, and in the autochthonous Zone Tirschenreuth- Mähring (ZTM) and the adjacent Moldanubian sensu strictu, on the other. Owing to the absence of age criteria, our results cannot be used, so far, to reconstruct the paleogeographical position of the individual tectonic units, based on the geochemical characteristics of their respective metabasites.
No abstract available
Hierarchical structures among male individuals in a population are frequently reflected in differences in aggressive and reproductive behaviour and access to the females. In general social dominance requires large investments which in turn may have to be compensated for by high reproductive success. However, this hypothesis has so far only been sufficiently tested in small mating groups due to the difficulties of determining paternity by classical methods using non-molecular markers. DNA fingerprinting overcomes these problems offering the possibility to determine genetic relationships and mating patterns within larger groups. Using this approach we have recently shown (Schartl et al., 1993) that in the poeciliid fish Limia perugiae in small mating groups the dominant male has 100% mating success, while in larger groups its contribution to the offspring unexpectedly drops to zero. The reproductive failure under such social conditions is explained by the inability of the ex-male to protect all the females simultaneously against mating attempts of his numerous subordinate competitors.
Deoxyribozymes are artificially evolved DNA molecules with catalytic abilities. RNA-cleaving deoxyribozymes have been recognized as an efficient tool for detection of modifications in target RNAs and provide an alternative to traditional and modern methods for detection of ribose or nucleobase methylation. However, there are only few examples of DNA enzymes that specifically reveal the presence of a certain type of modification, including N6-methyladenosine, and the knowledge about how DNA enzymes recognize modified RNAs is still extremely limited. Therefore, DNA enzymes cannot be easily engineered for the analysis of desired RNA modifications, but are instead identified by in vitro selection from random DNA libraries using synthetic modified RNA substrates. This protocol describes a general in vitro selection stagtegy to evolve new RNA-cleaving DNA enzymes that can efficiently differentiate modified RNA substrates from their unmodified counterpart.
Nitrosation of dietary components has been combined with the 4-(para-nitrobenzyl)pyridine (NBP) colorimetric test for screening alkylating agents and with the Ames test for the detection of mutagenic activity. This allowed the investigation of short-hved nitrosation products of dietary components which generate electrophilic degradation products requiring no metabolic activation (natural amino acids and some derivatives, ureas, guanidines, primary alkyl and aryl amines). In a first system, precursor, nitrous acid and NBP were present simultaneously. All amino acids tested, except glutamic acid and glutamine, gave positive results. The reactivities spanned more than three orders of magnitude, with the aromatic amino acids and methionine the most active; two primary amines, tryptamine and histamine, were also strongly reactive. All guanidines tested, except the amino acid arginine, gave negative results. A second system consisted of two phases: NBP was added only after destruction of residual nitrite and adjustment of the pH to neutrality. This system was useful for the study of ureas, which are stable in acid but not in neutral media. The range of responses covered more than two orders of magnitude. Most amino acids and primary amines also gave positive results, but could be assessed only after analysing the kinetics of the competing reactions and choosing appropriate reaction times. In a third system, Salmonella typhimurium strain TA1OO replaced NBP. Representatives of the class of amino acids, ureas, the primary amine tryptamine, and aniline became higbly mutagenic upon nitrosation. Methylguanidine was only weakly mutagenic under the present assay conditions. The results indicate that further studies with unstable nitrosation products of dietary components are required to understand more thoroughly the role of endogenous nitrosation in gastric cancer.
Experimental research on memory development has typically focused on the description of universal development trends across the life span and the identification of major sources of development within this domain. However, there is a lack of studies investigating the preconditions and effects of interindividual variability within age groups across different memory tasks. Similarly, our knowledge about the stability of interindividual differences across the life span as well as the sources and the amount of intraindividual variability across memory tasks is scarce. In the present chapter, we concentrate on these neglected issues. First, theoretical assumptions concerning the interindividual and intraindividual variability of memory development are discussed. Next, empirical evidence is presented that seems suited to document the importance of these neglected issues. While we try to give a representative account of the literature, the emphasis is on more recent studies of memory development in children and elderly adults conducted in our laboratory. The results demonstrate that age-related changes and individual differences in the knowledge base are particularly important for describing and explaining individual differences in memory develoment. In comparison, the rote of stable individual differences in basic memory capacities in explaining variations in memory development is less clear given tbe conflicting empirical evidence. In the final section of the chapter consequences for future research are discussed.
Children's information processing of risky choice alternatives was investigated in two studies without using verbal reports. In Study 1, the ability to integrate the probabilities and the payoffs of simple bets was examined using the rating scale methodology. Children's choices among three of those simple bets were recorded also. By cross-classifying the children's choice and rating behavior it was shown that a three-stage developmental hypothesis of decision making is not sufficient. A four-stage hypothesis is proposed. In Study 2, the influence of enlarging the presented number of alternatives from two to three and the influence of the similarity of the alternatives on children's choice probabilities was examined with those bets. Children's choice behavior was probabilistic and was influenced only by enlarging the presented number of alternatives. These results suggest that a Bayesian approach, based on two probabilistic choice models, should not be applied in order to analyze children's choice behavior. The functional measurement approach is, as was demonstrated in Study 1, a powerful implement to further the understanding of the development of decision making.
Starting with a terminological and phenomenological perspective on the question “What is an emotion?”, particularly as developed by Aaron Ben Zeʾev , the kiling scene in the book of Judith (Jdt 12:10–13:9 is analysed. This crucial scene in the book’s plot reports the intense emotions of Holofernes but nothing is said about any emotions on the part of of Judith. The only emotional glimpse occurs in Judith’s short prayers in the killing scene. The highly emotional Holofernes and the unemotional Judith together reveal that Holofernes is already made “headless” by his own emotions, whereas the unemotional Judith, unencumbered by emotions, is able to behead the “headless” Holofernes.
In 3 Maccabees, kingship as a form of rule is addressed on two levels: On the political level the question about a good king is addressed against the background of Hellenistic understandings of kingship, using the example of Ptolemy IV Philopator. This king is portrayed at the beginning of 3 Maccabees as a successful, positive, Hellenistic ruler, but one whose good rule goes off the rails. This analysis of the ideal of Hellenistic rule (cf. 3 Macc. 3:12-29; 6:24-28; 7:1-9) is then taken to a theological level: the God of Israel is portrayed as the true good king, the Soter who saves his people in their time of greatest trial (6:29, 32; 7:16). By these means the many divine epithets that are a striking feature of 3 Maccabees are incorporated into the narrative (cf. 2:2-3). Thereby 3 Maccabees not only thematises the conflict with a Hellenistic king who exploits his power in diverse ways but also focuses in a concentrated way the notion of a good (Hellenistic) king into the notion of God as king and ruler.
Memory development
(1994)
Metaphors, Dead and Alive
(2023)
This paper examins how the medieval distinction between proper and improper signification can give a plausible explanation of both metaphorical use and the usual transformations a language can undergo. I will show how Thomas Aquinas distinguishes between ordinary ambiguous terms and metaphors, whereas William of Ockham and Walter Burley do not leave room for this distinction. I will argue that Ockham’s conception of transfer of sense through subsequent institution of words is best thought of as an explanation of how ordinary usage can contain ambiguities, whereas Burley’s conception of transfer of sense without new imposition is more plausible when it comes to explaining metaphors. If metaphorical use is lumped together with equivocation, the account of how they work cannot do full justice to either, an insight that we already find in Peter Abelard, if not in Boethius.
The potential health risk posed by the endogenous formation of N-nitroso compounds (NOC) from nitrosation of dietary ureas, guanidines, amides, amino acids and amanes (primary, secondary and aromatic) was estimated according to the model:
Risk = ( daily intake of precursor] X (gastric concentration of nitrite ]n X [nitrosatability rate constant] X [cilrcinogenicity of derivative].
The daily intakes ofthese compound classes span five orders ofmagnitude (100 g/day amides, top; 1-10 mg/day secondary amines, ureas, bottom); the nitrosation rate constants span seven orders of magnitude (aryl amines, ureas, top; amides, secondary amines, bottom); and the carcinogenicity estimates span a 10 000-fold range from 'very strong' to 'virtually noncarcinogenic'. The resulting risk estimates likewise span an enormous range (nine orders of magnitude ): dietary ureas and aromatic amines combined with high nitrite concentration could pose as great a risk as the intake of preformed N-nitrosodimethylamine in the diet. In contrast, the risk posed by the in-vivo nitrosation of primary and secondary amines is probably negligible. The risk contributed by amides (including protein), guanidines and primary amino acids is intermediate between these two extremes.
A panel of simple repetitive oligonucleotide probes has been designed and tested for multilocus DNA fingerprinting in some 200 fungal, plant and animal species as well as man. To date at least one of the probes has been found to be informative in each species. The human genome, however, has been the major target of many fingerprintins studies. Using the probe (CAC)5 or (GTG)5, individualization of all humans is possible except for monozygotic twins. Paternity analyses are now perfonned on a routine basis by the use of multilocus fingerprints, inctuding also cases of deficiency, i.e. where one of the parents is not available for analysis. In forensie science stain analysis is feasible in all tissue remains containing nuc)eated cells. Depending on the degree of DNA degradation a variety of oligonucleotides are informative, and they have been proven useful in actual case work. Advantages in comparison to other methods including enzymatic DNA amplification techniques (PCR) are evident. Fingerprint patterns of tumors may be changed due to the gain or loss of chromosomes and/or intrachromosomal deletion and amplification events. Locus-specific probes were isolated from the human (CAC)5/( GTG)5 fingerprint with a varying degree of informativeness (monomorphic versus truly hypervariable markers). The feasibility of three different approaches. for the isolation of hypervariable mono-locus probes was evaluated. Finally, one particular mixed simple (gt)n(ga)m repeat locus in the second intron of the HLA-DRB genes has been scrutinized to allow comparison of the extent of exon-encoded (protein-) polymorphisms versus intronie bypervariability of simple repeats: adjacent to a single gene sequence (e.g. HLA-DRB1*0401) many different length alleles were found. Group-specific structures of basic repeats were identified within the evolutionarily related DRB alleles. As a further application it is suggested here that due to the ubiquitous interspersion of their targets, short probes for simple repeat sequences are especially useful tools for ordering genomic cosmid, yeast artificial chromosome and phage banks.
Adenosine modulates a variety of physiological functions via membrane-bound receptors. These receptors couple via G proteins to adenylate cyclase and K+channels. The A1 subtype mediates an inhibition of adenylate cyclase and an opening of K+-channels, and the A2 subtype a Stimulation of adenylate cyclase. Both subtypes have been characterized by radioligand binding. This has facilitated the development of agonists and antagonists with more than 1000-fold A1 selectivity. A1-selective photoaffinity labels have been used for the biochemical characterization of A1 receptors and the study of their coupling to adenylate cyclase. Such selective ligands allow the analysis of the involvement of adenosine receptors in physiological functions. Selective interference with adenosine receptors provides new pharmacological tools and eventually new therapeutic approaches to a number of pathophysiological states.
Internal characteristics such as depressed mood, anxiety and general negative emotions are accompanied, particularly during depressive illness, by changes in observable behaviour. Accordingly, the following questions may be examined: are intra-individual changes in speech and gaze behaviour related to changes in the internal psychopathological state? Further, do these changes occur synchronously to changes in the state of subjective well-being? A longitudinal study was made on depressed patients. Their behaviour was observed during standardised interviews and diagnostic-therapeutic discussions held at regu~ lar intervals. Various speech and gaze parameters were examined with respect to their coordination and their relationship to the subjective state of well-being. Considerable variation was found in the temporal relationship amongst these variables. The results are discussed with respect to the relevance of speech parameters and the coordination of verbal and nonverbal behaviour as indicators of the psychopathological condition.