Comparison of a second-generation trabecular bypass (iStent inject) to ab interno trabeculectomy (Trabectome) by exact matching
Please always quote using this URN: urn:nbn:de:bvb:20-opus-232613
- Purpose To achieve a highly balanced comparison of trabecular bypass stenting (IS2, iStent inject) with ab interno trabeculectomy (T, Trabectome) by exact matching. Methods Fifty-three IS2 eyes were matched to 3446 T eyes. Patients were matched using exact matching by baseline intraocular pressure (IOP), the number of glaucoma medications, and glaucoma type, and using nearest neighbor matching by age. Individuals without a close match were excluded. All surgeries were combined with phacoemulsification. Results A total of 78 eyes (39 inPurpose To achieve a highly balanced comparison of trabecular bypass stenting (IS2, iStent inject) with ab interno trabeculectomy (T, Trabectome) by exact matching. Methods Fifty-three IS2 eyes were matched to 3446 T eyes. Patients were matched using exact matching by baseline intraocular pressure (IOP), the number of glaucoma medications, and glaucoma type, and using nearest neighbor matching by age. Individuals without a close match were excluded. All surgeries were combined with phacoemulsification. Results A total of 78 eyes (39 in each group) could be matched as exact pairs with a baseline IOP of 18.3 ± 5.1 mmHg and glaucoma medications of 2.7 ± 1.2 in each. IOP in IS2 was reduced to 14.6 ± 4.2 mmHg at 3 months and in T to a minimum of 13.1 ± 3.2 mmHg at 1 month. In IS2, IOP began to rise again at 6 months, eventually exceeding baseline. At 24 months, IOP in IS2 was 18.8 ± 9.0 mmHg and in T 14.2 ± 3.5 mmHg. IS2 had a higher average IOP than T at all postoperative visits (p < 0.05 at 1, 12, 18 months). Glaucoma medications decreased to 2.0 ± 1.5 in IS2 and to 1.5 ± 1.4 in T. Conclusion T resulted in a larger and sustained IOP reduction compared with IS2 where a rebound occurred after 6 months to slightly above preoperative values.…
Author: | Yousef Al Yousef, Alicja Strzalkowska, Jost Hillenkamp, André Rosentreter, Nils A. Loewen |
---|---|
URN: | urn:nbn:de:bvb:20-opus-232613 |
Document Type: | Journal article |
Faculties: | Medizinische Fakultät / Augenklinik und Poliklinik |
Language: | English |
Parent Title (English): | Graefe's Archive for Clinical and Experimental Ophthalmology |
ISSN: | 0721-832X |
Year of Completion: | 2020 |
Volume: | 258 |
Pagenumber: | 2775–2780 |
Source: | Graefe's Archive for Clinical and Experimental Ophthalmology 258, 2775–2780 (2020). https://doi.org/10.1007/s00417-020-04933-z |
DOI: | https://doi.org/10.1007/s00417-020-04933-z |
Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Tag: | ab interno trabeculectomy; exact matching; glaucoma surgery; iStent; trabectome; trabecular bypass stent |
Release Date: | 2021/06/30 |
Licence (German): | CC BY: Creative-Commons-Lizenz: Namensnennung 4.0 International |