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Sonstige beteiligte Institutionen
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Verbalkomplexe im \(Jarama\)
(2015)
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Maß und Exzess: Emotionalität in den Amor-Lauden des italienischen Mystikers Jacopone da Todi
(2015)
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"...using different names, as Zeus and Dis" (Arist 16). Concepts of "God" in the letter of Aristeas
(2016)
The “Letter of Aristeas” recounts the translations of the Hebrew Bible into Greek. Probably originating in the 2nd century BCE1, the book tells a legend of how the translation of the Torah into Greek came into being. This shows that translating a holy, canonical text or the first time needed explication. Notably, the translation of the godly nomos (Arist 3) comparatively takes up little space (Arist 301–307). And it has to be noted, that “God” is seldom a topic in the Book of Aristeas. The word (ὁ) θεός “God” is found in only three contexts: in the dialogue between king Ptolemaios and Aristeas (Arist 15–21), in the dialogue of the high priest Eleazar and Aristeas (Arist 121–171; above all 128; 130–141; 155–166; 168) and in the question-and-answer-speech during the symposium at the Ptolemaic royal court between the king and the Jewish scholars (Arist 184–294).
In analysing the different statements regarding God, the frame of the narrative is of decisive importance: In the Book of Aristeas, “Aristeas” (Ἀριστέας), who writes in Greek, presents himself as the author, but he is also part of the story. Accordingly, Aristeas is the narrator, who tells the story from his own point of view, and at the same time, he is a character in the ‘world’ of the text. This Aristeas presents himself as a Greek and a Non-Jew (Arist 16; 121–171), who already wrote a book (Arist 6) and plans further publications (Arist 322). In the double-role as narrator of the text and protagonist in the text, Aristeas has to be differentiated from the (real) writer/author of the Book of Aristeas, who possibly was Jewish. That means that the (real, probably Jewish) author of the Book of Aristeas presents (or invents) “Aristeas” and gives him the role of the narrator of his text.3 The author portrays Aristeas as a Greek, non-Jewish character, who is a servant of the royal court. This differentiation between narrator and writer/author is of crucial importance for the question of the different conceptions of God in the Book of Aristeas.
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Starting with a terminological and phenomenological perspective on the question “What is an emotion?”, particularly as developed by Aaron Ben Zeʾev , the kiling scene in the book of Judith (Jdt 12:10–13:9 is analysed. This crucial scene in the book’s plot reports the intense emotions of Holofernes but nothing is said about any emotions on the part of of Judith. The only emotional glimpse occurs in Judith’s short prayers in the killing scene. The highly emotional Holofernes and the unemotional Judith together reveal that Holofernes is already made “headless” by his own emotions, whereas the unemotional Judith, unencumbered by emotions, is able to behead the “headless” Holofernes.
59. Schale (Typus B)
(1991)
56. Schale (Typus B)
(1991)
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Following the narration of a rescue from a hopeless situation the book of Judith ends with a hymnically fashioned song, which combines the gratitude for the rescue with a review on what occurred. Remarkably, this narratological important part of the narrative ends with a phrasing which not only differs from the characteristic style of the final speech but also cites the end of the book of Isaiah (66:24). This is the point of departure for the considerations. They are going to trace the meaning and literary function of this foreign imagery from Isaiah 66:24 in the narrative of Judith.
Die Juditerzählung und das Danielbuch sind – auf den ersten Blick – so unterschiedliche Schriften, dass eine Beziehung zwischen ihnen anzunehmen wenig plausibel erscheint: auf der einen Seite die Juditerzählung, eine "sex and crime"-Geschichte, die schillernd und ambivalent die Geschichte der Bedrohung und Rettung Israels durch die schöne Judit mit einem Happy End erzählt; auf der anderen Seite eine gewachsene, mehrsprachige, apokalyptische Schrift mit brutalen Ermordungsversuchen, wundersamen Rettungen und verstörenden Visionsschilderungen.
Als konfessionell gebundenes Unterrichtsfach (mit Notengebung) an staatlichen Schulen will der Religionsunterricht einen Vermittlungsprozess gestalten, in dem - abgestimmt auf Alter und Entwicklungsstand der Schülerinnen und Schüler - religiöses Lernen stattfindet, das kirchlicher Lehre und wissenschaftlicher Reflexion verpflichtet ist. Das Alte Testament ist als eine unter den anderen theologischen Disziplinen in dieses Spannungsfeld eingebunden. Exemplarisch soll für die alttestamentliche Exegese der Transfer von der Fachwissenschaft zur Fachdidaktik erörtert werden. In diesem Fall richtet sich somit die Frage, was Kinder und Jugendliche im Religionsunterricht im Umgang mit dem Alten Testament lernen sollen, nicht nur an die Religionspädagogik, sondern auch an die Bibelwissenschaften.
" ... der Schuld, Vergehen und Sünde vergibt" (Ex 34,7): Sünde und Schuld in der Hebräischen Bibel
(2012)
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Antiochus Epiphanes und der epiphane Gott. Gefühle, Emotionen und Affekte im Zweiten Makkabäerbuch
(2012)
Das Zweite Makkabäerbuch ist eine absichtsvoll komponierte Erzählung, die ihr Erzählinteresse in der Vorrede (2Makk 2,19–32) und im Epilog (2Makk 15,37–39) benennt. Die Erzählung soll – so die Selbstauskunft der Erzählung im Vorwort – den Leserinnen und Lesern zur Psnchagogia, „Seelenführung, Vergnügung, Lockung“, zur eukopia, „Leichtigkeit“ sowie zur opheleia, „Vorteil, Nutzen, nützlichen Kenntnis“ dienen (2Makk 2,25). Damit präsentiert sich das Zweite Makkabäerbuch als eine absichtsvolle literarische Erzählung, die ganz bewusst bei den Leserinnen und Lesern emotionale Wirkung, Gefühle und Affekte hervorrufen will.
Dieses Ziel wird gleich zu Beginn der Erzählung auf der Kommunikationsebene zwischen Erzählstimme und Lesenden benannt. Das auf diese Weise offengelegte Vorhaben der Erzählung lässt zunächst fragen, wie die emotionale Wirkung bei den Leserinnen und Lesern erzielt werden soll. Darüber hinaus ist die viel grundlegendere Frage zu stellen, warum es für das Zweite Makkabäerbuch von so zentralem Interesse ist, Emotionen bei den Rezipienten hervorzurufen.
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kulbābu
(1991)
Hymnen der Hethiter
(1994)
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EA 24
(1987)
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Der Beitrag diskutiert die Probleme der Veränderungsmessung im Rahmen der klassischen Testtheorie. Ausgehend von den Axiomen der klassischen Testtheorie (vgl. LoRD und NovrcK 1968) werden exemplarisch für den klinischen Bereich verschiedene Veränderungsindices abgeleitet. Diese werden zunächst vergleichend theoretisch diskutiert. In die Darstellung fließen dann herkömmliche Auswertungsstrategien der Veränderungsmessung ein (non parametrische Tests, Pfadanalyse, Cross-Lagged-Analysis, multivariate Varianzanalyse, Faktorenanalyse etc.). Eine Extension der klassischen Testtheorie stellt der Ansatz von BEREITER (1963), die Einführung änderungssensitiver Items, dar. - Alle methodischen Erwägungen sollen möglichst an Forschungsbeispielen der Klinischen Psychologie erörtert werden. Abschließend sollen für die Forschungspraxis Handlungskonzepte erkennbar sein.
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Hierarchical structures among male individuals in a population are frequently reflected in differences in aggressive and reproductive behaviour and access to the females. In general social dominance requires large investments which in turn may have to be compensated for by high reproductive success. However, this hypothesis has so far only been sufficiently tested in small mating groups due to the difficulties of determining paternity by classical methods using non-molecular markers. DNA fingerprinting overcomes these problems offering the possibility to determine genetic relationships and mating patterns within larger groups. Using this approach we have recently shown (Schartl et al., 1993) that in the poeciliid fish Limia perugiae in small mating groups the dominant male has 100% mating success, while in larger groups its contribution to the offspring unexpectedly drops to zero. The reproductive failure under such social conditions is explained by the inability of the ex-male to protect all the females simultaneously against mating attempts of his numerous subordinate competitors.
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Die Arbeit geht von der allgemeinen Feststellung aus, daß die Repräsentation von Wissen der Reduktion des Aufwandes von zu erwartenden Informationsverarbeitungsprozessen dient. Es werden verschiedene Anforderungen an die menschliche Informationsverarbeitung betrachtet, und es wird jeweils gefragt, welche Eigenschaften die Wissensrepräsentation haben muß, um diesen Anforderungen zu genügen. Im einzelnen werden die Objektwahrnehmung, die anschauliche Vorstellungstätigkeit, die Aufmerksamkeitssteuerung, die Erkennung semantischer Relationen, die Handlungskontrolle und der Erwerb von Wortbedeutungen betrachtet. Es wird die Schlußfolgerung gezogen, daß eine Repräsentation in diskreten symbolischen Einheiten der Dynamik der Wissensnutzung unter den verschiedenen Anforderungen wenig gerecht wird. Es scheint naheliegender, Wissen direkt in Handlungseinheiten zu repräsentieren. Solche Einheiten sollten Informationen über einzelne Handlungen mit Informationen über Situationskontexte verbinden, in denen die Handlungen erfolgreich verwendet worden sind. Die Vorteile einer solchen handlungsorientierten Wissensrepräsentation werden diskutiert.
Memory development
(1994)
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A panel of simple repetitive oligonucleotide probes has been designed and tested for multilocus DNA fingerprinting in some 200 fungal, plant and animal species as well as man. To date at least one of the probes has been found to be informative in each species. The human genome, however, has been the major target of many fingerprintins studies. Using the probe (CAC)5 or (GTG)5, individualization of all humans is possible except for monozygotic twins. Paternity analyses are now perfonned on a routine basis by the use of multilocus fingerprints, inctuding also cases of deficiency, i.e. where one of the parents is not available for analysis. In forensie science stain analysis is feasible in all tissue remains containing nuc)eated cells. Depending on the degree of DNA degradation a variety of oligonucleotides are informative, and they have been proven useful in actual case work. Advantages in comparison to other methods including enzymatic DNA amplification techniques (PCR) are evident. Fingerprint patterns of tumors may be changed due to the gain or loss of chromosomes and/or intrachromosomal deletion and amplification events. Locus-specific probes were isolated from the human (CAC)5/( GTG)5 fingerprint with a varying degree of informativeness (monomorphic versus truly hypervariable markers). The feasibility of three different approaches. for the isolation of hypervariable mono-locus probes was evaluated. Finally, one particular mixed simple (gt)n(ga)m repeat locus in the second intron of the HLA-DRB genes has been scrutinized to allow comparison of the extent of exon-encoded (protein-) polymorphisms versus intronie bypervariability of simple repeats: adjacent to a single gene sequence (e.g. HLA-DRB1*0401) many different length alleles were found. Group-specific structures of basic repeats were identified within the evolutionarily related DRB alleles. As a further application it is suggested here that due to the ubiquitous interspersion of their targets, short probes for simple repeat sequences are especially useful tools for ordering genomic cosmid, yeast artificial chromosome and phage banks.
Tbe alkylating potency of unstable N-nitrosamino acids and N-nitrosopeptides was investigated in vitro using 4-(para-nitrobenzyl)pyridine (NBP) as nucleophile. Of the amino acids, Met and those with an aromatic side chain were the most potent. The relative overall alkylating potency was 23:10:5:4:2:1: for Trp, Met, His, 1)rr, Phe and Gly, respectively. The homo-dipeptides were much more potent than the amino acids, with relative potencies of 400:110:100:8:3:1, for Trp-Trp, l)T-'I)T, Met-Met, Asp-Asp, Phe-Phe and Gly, respectively. In the one-phase reaction system (in which NBP is already present durlog the nitrosation reaction at acidic pH), all amino acids tested showed a second-order reaction for nitrite. In the two-phase system (in which NBP is added only after bringing the nitrosation reaction mixture to neutrality), all amino acids tested except one again showed a second-order reaction for nitrite (Phe, His, Asp and the dipeptide artiticial sweetener aspartame); only Met under these conditions bad a reaction order of one for nitrite. This could mean that nitrosation of the side chain of Metproduces a second N-nitroso product which is relatively stable in acid but reacts with NBP under neutral conditions. In the human stomach, this side-chain nitrosation might become more important than the reactions at the primary amino group, firstly because of the greater stability of the product(s) in acid and secondly because of the tirst-order reaction rate for nitrite. A decrease in nitrite concentration from the millimolar concentrations ofthe in-vitro assay to the micromolar concentrations in the stomach reduces the reaction rate by a factor of 1000 for the side-chain nitrosation, whereas a million-fold reduction will be observed for nitrosation of the amino group.
An improved 32P-postlabelling assay for detection and quantitation of styrene 7,8-oxide-DNA adducts
(1993)
Using DNA modified with [7-3H]styrene 7,8-oxide (SO) in vitro we have standardized the 32P-postlabelling assay for detecting SO-DNA adducts. Nuclease P 1-enriched adducts were 32P-labelled and purified by high-salt ( 4.0 M ammonium formate, pH 6.1} C1s reverse-phase TLC. After elution from the layer with 2-butoxyethanol:H20 (4:6), adducts were separated by two-dimensional PEI cellulose TLC in non-urea solvents (2.0 M ammonium formate, pH 3.5, and 2.7 M sodium phosphate, pH 5.6). One major, three minor and several trace adducts were detected. The efficiency of the kinase reaction depended on the ATP concentration. Use of standard labelling conditions (['Y· 32P]ATP, <3000 Ci/mmol; <2 Mikromol) resulted in poor ( 4-7%) adduct recovery. An ATP concentration of 40 Mikromol, however, increased the labeJling efficiency by a factor of 5-8 (35-55% based on 3H-SO labelied DNA). The results indicate that the new separation technique is suitable for the relatively polar SO-DNA adducts and that high labelling efficiency can be achieved.
Adenosine modulates a variety of physiological functions via membrane-bound receptors. These receptors couple via G proteins to adenylate cyclase and K+channels. The A1 subtype mediates an inhibition of adenylate cyclase and an opening of K+-channels, and the A2 subtype a Stimulation of adenylate cyclase. Both subtypes have been characterized by radioligand binding. This has facilitated the development of agonists and antagonists with more than 1000-fold A1 selectivity. A1-selective photoaffinity labels have been used for the biochemical characterization of A1 receptors and the study of their coupling to adenylate cyclase. Such selective ligands allow the analysis of the involvement of adenosine receptors in physiological functions. Selective interference with adenosine receptors provides new pharmacological tools and eventually new therapeutic approaches to a number of pathophysiological states.
Nitrosation of dietary components has been combined with the 4-(para-nitrobenzyl)pyridine (NBP) colorimetric test for screening alkylating agents and with the Ames test for the detection of mutagenic activity. This allowed the investigation of short-hved nitrosation products of dietary components which generate electrophilic degradation products requiring no metabolic activation (natural amino acids and some derivatives, ureas, guanidines, primary alkyl and aryl amines). In a first system, precursor, nitrous acid and NBP were present simultaneously. All amino acids tested, except glutamic acid and glutamine, gave positive results. The reactivities spanned more than three orders of magnitude, with the aromatic amino acids and methionine the most active; two primary amines, tryptamine and histamine, were also strongly reactive. All guanidines tested, except the amino acid arginine, gave negative results. A second system consisted of two phases: NBP was added only after destruction of residual nitrite and adjustment of the pH to neutrality. This system was useful for the study of ureas, which are stable in acid but not in neutral media. The range of responses covered more than two orders of magnitude. Most amino acids and primary amines also gave positive results, but could be assessed only after analysing the kinetics of the competing reactions and choosing appropriate reaction times. In a third system, Salmonella typhimurium strain TA1OO replaced NBP. Representatives of the class of amino acids, ureas, the primary amine tryptamine, and aniline became higbly mutagenic upon nitrosation. Methylguanidine was only weakly mutagenic under the present assay conditions. The results indicate that further studies with unstable nitrosation products of dietary components are required to understand more thoroughly the role of endogenous nitrosation in gastric cancer.